1X1X

water-mediate interaction at aprotein-protein interface

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: C-F
  • Int. Res.: 75
  • Norm. En. per Res.: -5.1113
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-0.6807	-73.484	-74.1647	27	2	1	2937	0	12	9
A-C	-14.0322	13.6304	-36.8061	-37.2079	42	3	0	1817	0	4	8
A-D	-68.3791	-56.404	-257.933	-382.7161	77	15	1	8804	6	33	27
B-C	0.0	-2.048	-35.5009	-37.5489	23	0	0	1413	0	9	7
B-E	-56.2756	-55.2343	-253.218	-364.7279	74	11	2	8787	7	33	26
C-E	0.0	0.0	-0.8452	-0.8452	10	0	0	108	0	9	3
C-F	-61.8013	-66.257	-255.286	-383.3443	75	10	2	8326	7	31	25

Interface residues

• A-B: ALA11A, ALA11B, ARG110A, ARG110B, ASP12A, ASP12B, ASP8A, ASP8B, GLN15A, GLN15B, ILE109A, ILE109B, ILE96A, ILE96B, LYS108A, LYS108B, LYS98A, LYS98B, PHE106A, PHE106B, PHE7A, PHE7B, THR100B, THR107A, THR107B, TYR97A, TYR97B
• A-C: ALA11C, ALA1A, ARG110C, ASN23A, ASN5A, ASN5C, ASN77A, ASN77C, ASN84A, ASP12C, ASP8A, ASP8C, GLN15C, GLN2A, GLN2C, GLY48A, GLY9A, GLY9C, ILE109C, ILE4A, ILE4C, ILE76A, LYS108C, LYS98C, PHE7A, PHE7C, PRO21A, SER80A, THR100C, THR107C, THR16C, THR6A, THR6C, THR79A, THR79C, TYR13C, TYR24A, TYR78A, VAL10A, VAL10C, VAL3A, VAL3C
• A-D: ALA25D, ALA36D, ALA37A, ALA40D, ALA76D, ALA77D, ALA82D, ARG59A, ARG75D, ARG83A, ARG87A, ASN33D, ASN58A, ASN84A, ASP101A, ASP35D, ASP39D, ASP54A, ASP75A, ASP83D, ASP86A, GLN104A, GLN31A, GLN72D, GLU28D, GLU32D, GLU46D, GLU60A, GLU73A, GLU80D, GLY31D, GLY40A, GLY43D, GLY61A, GLY81A, GLY81D, HIS102A, HIS17D, ILE13D, ILE51A, ILE55A, LEU26D, LEU34D, LEU37D, LEU41D, LEU63A, LEU89A, LYS1D, LYS27A, LYS39A, LYS62A, PHE106A, PHE56A, PHE74D, PHE82A, PRO27D, SER28A, SER38A, SER57A, SER69D, SER85A, THR100A, THR105A, THR42D, THR99A, TRP35A, TRP38D, TRP44D, TYR103A, TYR29D, TYR30D, TYR47D, TYR78A, VAL36A, VAL45D, VAL70D, VAL73D
• B-C: ARG59B, ASN58B, ASP101B, ASP93C, GLN104B, GLN15C, GLU60B, GLY61B, HIS18C, LEU14C, LEU63B, LYS19C, LYS62B, PHE106B, PRO64B, THR105B, THR107B, THR16C, TRP94C, TYR103B, TYR13C, TYR17C, TYR97B
• B-E: ALA36E, ALA37B, ALA40E, ALA76E, ALA77E, ALA82E, ARG59B, ARG75E, ARG83B, ARG87B, ASN33E, ASN58B, ASN84B, ASP101B, ASP35E, ASP39E, ASP54B, ASP75B, ASP83E, ASP86B, GLN104B, GLN31B, GLN72E, GLU28E, GLU32E, GLU46E, GLU60B, GLU73B, GLU80E, GLY31E, GLY40B, GLY43E, GLY61B, GLY81B, GLY81E, HIS102B, HIS17E, ILE13E, ILE51B, ILE55B, LEU26E, LEU34E, LEU37E, LEU41E, LEU63B, LEU89B, LYS27B, LYS39B, LYS62B, PHE106B, PHE56B, PHE74E, PHE82B, PRO27E, SER28B, SER38B, SER57B, SER69E, SER85B, THR100B, THR105B, THR42E, THR99B, TRP35B, TRP38E, TRP44E, TYR103B, TYR29E, TYR30E, TYR47E, VAL36B, VAL45E, VAL70E, VAL73E
• C-E: ARG72C, ASN33E, ASN65E, GLU64E, GLY68C, HIS18C, LYS19C, SER14E, SER92C, THR70C
• C-F: ALA36F, ALA37C, ALA40F, ALA76F, ALA77F, ALA82F, ARG59C, ARG75F, ARG83C, ARG87C, ASN33F, ASN58C, ASN84C, ASP101C, ASP35F, ASP39F, ASP54C, ASP75C, ASP83F, ASP86C, GLN104C, GLN31C, GLN72F, GLU28F, GLU32F, GLU46F, GLU60C, GLU73C, GLU80F, GLY31F, GLY40C, GLY43F, GLY61C, GLY81C, GLY81F, HIS102C, HIS17F, ILE13F, ILE51C, ILE55C, LEU26F, LEU34F, LEU37F, LEU41F, LEU63C, LEU89C, LYS1F, LYS27C, LYS39C, LYS62C, PHE106C, PHE56C, PHE74F, PHE82C, PRO27F, SER28C, SER38C, SER57C, SER69F, SER85C, THR100C, THR105C, THR42F, THR99C, TRP35C, TRP38F, TRP44F, TYR103C, TYR29F, TYR30F, TYR47F, VAL36C, VAL45F, VAL70F, VAL73F