1X0U

crystal structure of the carboxyl transferase subunit of putative pcc of sulfolobus tokodaii

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: B-E
  • Int. Res.: 423
  • Norm. En. per Res.: -4.243
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-51.9489	-62.8429	-310.709	-425.5008	128	11	6	13616	6	53	54
A-C	-74.5998	-67.7199	-331.601	-473.9207	135	18	7	14344	6	57	57
A-D	-186.975	-141.2249	-1439.08	-1767.2799	430	97	68	60577	15	105	135
A-E	0.0	0.0	-0.5337	-0.5337	12	2	1	528	0	2	5
A-F	-5.9676	-42.6954	-21.4124	-70.0754	28	0	0	1083	3	19	7
B-C	-82.0967	-95.4081	-362.348	-539.8528	138	23	7	15549	10	54	58
B-D	-18.4092	-61.4256	-16.0178	-95.8526	32	6	0	1249	5	23	7
B-E	-215.2344	-145.9365	-1433.6	-1794.7709	423	111	70	60749	14	107	134
B-F	0.0	0.0	-17.292	-17.292	12	0	1	633	0	2	5
C-D	0.0	0.0	-17.2855	-17.2855	13	0	1	711	0	2	5
C-E	-12.6552	-50.6541	-19.5022	-82.8115	26	1	0	1018	4	18	6
C-F	-199.1645	-141.4122	-1440.29	-1780.8667	425	84	71	58760	12	105	133
D-E	-76.5517	-57.7194	-308.806	-443.0771	125	20	5	13852	5	54	55
D-F	-60.636	-70.3299	-323.611	-454.577	132	21	7	14499	8	57	57
E-F	-42.5072	-62.4652	-343.184	-448.1565	134	13	7	14710	6	52	54

Interface residues

• A-B: ALA119B, ALA123B, ALA128B, ALA275A, ALA425A, ALA430A, ALA434A, ALA475A, ALA480A, ALA481A, ALA501A, ALA63B, ALA67B, ARG118B, ARG17B, ARG497A, ARG510A, ARG513A, ARG66B, ARG76B, ARG92B, ASN114B, ASN257B, ASN284A, ASN476A, ASN57B, ASP272A, ASP285A, ASP426A, ASP487A, ASP488A, ASP494A, ASP80B, GLN280A, GLU10B, GLU121B, GLU14B, GLU15B, GLU260B, GLU279A, GLU482A, GLU491A, GLU504A, GLU511A, GLU58B, GLY127B, GLY277A, GLY424A, GLY484A, GLY502A, GLY79B, GLY85B, GLY87B, GLY91B, ILE13B, ILE281A, ILE403A, ILE420A, ILE490A, ILE499A, ILE59B, LEU122B, LEU124B, LEU12B, LEU16B, LEU19B, LEU423A, LEU427A, LEU485A, LEU503A, LEU506A, LYS115B, LYS11B, LYS125B, LYS20B, LYS402A, LYS421A, LYS472A, LYS483A, LYS493A, LYS507A, LYS509A, LYS55B, LYS6B, LYS88B, MET259B, MET505A, MET60B, PHE62B, PHE77B, PHE95B, PRO283A, PRO401A, PRO432A, PRO477A, PRO492A, PRO7B, PRO8B, SER256B, SER422A, THR111B, THR276A, THR399A, THR433A, THR508A, THR61B, THR64B, THR65B, THR84B, THR93B, TRP431A, TRP479A, TRP86B, TYR24B, TYR429A, TYR478A, TYR512A, TYR78B, VAL126B, VAL278A, VAL282A, VAL428A, VAL486A, VAL489A, VAL498A, VAL500A, VAL94B, VAL9B
• A-C: 2115CB6.4031, ALA119A, ALA123A, ALA128A, ALA286C, ALA425C, ALA430C, ALA434C, ALA468C, ALA475C, ALA480C, ALA481C, ALA501C, ALA63A, ALA67A, ARG118A, ARG17A, ARG273C, ARG471C, ARG497C, ARG510C, ARG513C, ARG66A, ARG76A, ARG92A, ASN114A, ASN257A, ASN284C, ASN476C, ASN57A, ASP272C, ASP285C, ASP426C, ASP487C, ASP488C, ASP494C, ASP80A, GLN18A, GLN280C, GLU10A, GLU121A, GLU14A, GLU15A, GLU21A, GLU260A, GLU279C, GLU482C, GLU491C, GLU504C, GLU511C, GLU58A, GLY127A, GLY424C, GLY484C, GLY502C, GLY79A, GLY85A, GLY87A, GLY91A, ILE13A, ILE281C, ILE403C, ILE420C, ILE490C, ILE499C, ILE59A, LEU122A, LEU124A, LEU12A, LEU16A, LEU19A, LEU427C, LEU485C, LEU503C, LEU506C, LYS115A, LYS11A, LYS125A, LYS20A, LYS402C, LYS421C, LYS464C, LYS472C, LYS483C, LYS493C, LYS507C, LYS509C, LYS55A, LYS6A, LYS6A5, LYS88A, MET259A, MET505C, MET60A, PHE56A, PHE62A, PHE77A, PHE95A, PRO283C, PRO401C, PRO432C, PRO477C, PRO492C, PRO7A, PRO8A, SER256A, SER422C, THR111A, THR399C, THR433C, THR508C, THR61A, THR64A, THR65A, THR68A, THR84A, THR93A, TRP431C, TRP479C, TRP86A, TYR24A, TYR429C, TYR478C, TYR512C, TYR78A, VAL126A, VAL278C, VAL282C, VAL428C, VAL486C, VAL489C, VAL498C, VAL500C, VAL94A, VAL9A
• A-D: ALA113A, ALA113D, ALA139A, ALA139D, ALA145A, ALA145D, ALA153A, ALA153D, ALA161A, ALA161D, ALA175A, ALA175D, ALA176A, ALA176D, ALA179A, ALA179D, ALA184A, ALA184D, ALA313A, ALA313D, ALA346D, ALA347A, ALA347D, ALA350A, ALA350D, ALA351A, ALA351D, ALA359A, ALA359D, ALA389A, ALA389D, ALA394A, ALA394D, ALA396A, ALA396D, ALA398A, ALA398D, ALA414A, ALA414D, ALA417A, ALA417D, ALA425A, ALA425D, ALA437A, ALA437D, ALA444A, ALA444D, ALA480A, ALA480D, ALA481A, ALA67A, ALA67D, ARG140A, ARG140D, ARG352A, ARG352D, ARG355A, ARG355D, ARG386A, ARG386D, ARG446A, ARG446D, ARG450A, ARG466A, ARG466D, ARG510A, ARG510D, ARG513A, ARG513D, ARG66A, ARG66D, ASN158A, ASN158D, ASN258A, ASN258D, ASN361A, ASN361D, ASN476A, ASN476D, ASN520A, ASN520D, ASP187A, ASP187D, ASP219A, ASP219D, ASP343A, ASP343D, ASP345A, ASP345D, ASP348A, ASP348D, ASP358A, ASP358D, ASP378A, ASP378D, CYS357A, CYS357D, GLN142A, GLN142D, GLN167A, GLN167D, GLN218A, GLN218D, GLN379A, GLN379D, GLU110A, GLU110D, GLU121A, GLU121D, GLU143A, GLU143D, GLU149A, GLU149D, GLU205A, GLU205D, GLU213A, GLU213D, GLU214A, GLU380A, GLU380D, GLU397A, GLU397D, GLU442A, GLU442D, GLU452D, GLU469A, GLU469D, GLU482A, GLU482D, GLU511A, GLU511D, GLU69A, GLU69D, GLY127A, GLY127D, GLY138A, GLY138D, GLY144A, GLY144D, GLY150A, GLY150D, GLY152A, GLY152D, GLY163A, GLY163D, GLY177A, GLY177D, GLY178A, GLY178D, GLY203A, GLY203D, GLY212A, GLY221A, GLY221D, GLY222A, GLY222D, GLY231A, GLY231D, GLY372A, GLY372D, GLY376A, GLY376D, GLY383A, GLY383D, GLY388A, GLY388D, GLY412A, GLY412D, GLY413A, GLY413D, GLY424A, GLY424D, GLY440A, GLY440D, GLY443A, GLY443D, GLY484A, GLY484D, GLY519A, GLY519D, GLY71A, HIS226A, HIS226D, HIS234A, HIS234D, HIS309A, HIS309D, HIS387A, HIS387D, HIS415A, HIS415D, HIS518A, HIS518D, ILE141A, ILE141D, ILE165A, ILE165D, ILE189A, ILE189D, ILE206A, ILE206D, ILE342A, ILE342D, ILE344A, ILE344D, ILE354A, ILE354D, ILE362A, ILE362D, ILE384A, ILE384D, ILE385A, ILE385D, ILE416A, ILE416D, ILE420A, ILE420D, ILE436A, ILE436D, ILE447A, ILE447D, ILE521A, ILE521D, LEU108A, LEU108D, LEU124A, LEU124D, LEU146A, LEU146D, LEU148A, LEU148D, LEU185A, LEU185D, LEU211A, LEU211D, LEU220A, LEU220D, LEU392A, LEU392D, LEU423A, LEU423D, LEU448A, LEU448D, LEU473A, LEU473D, LEU485A, LEU485D, LEU523A, LEU523D, LEU72A, LEU72D, LYS125A, LYS125D, LYS156A, LYS156D, LYS208A, LYS208D, LYS229A, LYS229D, LYS349A, LYS349D, LYS382A, LYS382D, LYS390A, LYS390D, LYS402A, LYS402D, LYS421A, LYS421D, LYS483A, LYS483D, LYS509A, LYS509D, LYS516A, LYS516D, LYS517A, LYS517D, MET157A, MET157D, MET160A, MET160D, MET171A, MET171D, MET191A, MET191D, MET199A, MET199D, MET259A, MET259D, MET391A, MET391D, PHE155A, PHE155D, PHE188A, PHE188D, PHE200A, PHE200D, PHE217A, PHE217D, PHE338D, PHE353A, PHE353D, PHE356A, PHE356D, PHE360A, PHE360D, PHE395A, PHE395D, PHE474A, PHE474D, PHE70A, PHE70D, PRO166A, PRO166D, PRO183A, PRO183D, PRO204A, PRO204D, PRO371D, PRO375A, PRO375D, PRO401A, PRO401D, PRO441A, PRO441D, PRO477A, PRO515A, PRO515D, PRO522A, PRO522D, SER107A, SER107D, SER147A, SER147D, SER162A, SER162D, SER182A, SER182D, SER216A, SER216D, SER230A, SER230D, SER341A, SER341D, SER410A, SER410D, SER419A, SER422A, SER422D, THR186A, THR186D, THR202A, THR202D, THR207A, THR207D, THR228A, THR228D, THR377A, THR377D, THR399A, THR399D, THR439A, THR439D, THR68A, THR68D, TRP312A, TRP312D, TRP479A, TRP479D, TYR120A, TYR120D, TYR151A, TYR151D, TYR181A, TYR181D, TYR198A, TYR198D, TYR373A, TYR373D, TYR381A, TYR381D, TYR393A, TYR393D, TYR411A, TYR411D, TYR449A, TYR449D, TYR470A, TYR470D, TYR512A, TYR512D, TYR514A, TYR514D, VAL117A, VAL117D, VAL126D, VAL154A, VAL154D, VAL159A, VAL159D, VAL164A, VAL164D, VAL180A, VAL180D, VAL201A, VAL201D, VAL209A, VAL209D, VAL210A, VAL210D, VAL215A, VAL215D, VAL225A, VAL225D, VAL232A, VAL232D, VAL233A, VAL233D, VAL374A, VAL374D, VAL400A, VAL400D, VAL428A, VAL428D, VAL438A, VAL438D, VAL445A, VAL445D, VAL486A, VAL486D
• A-E: ARG510A, ARG510E, ARG513A, ARG513E, GLU511A, GLU511E, PRO515A, PRO515E, TYR512A, TYR512E, TYR514A, TYR514E
• A-F: ALA145A, ALA67A, ALA67F, ARG118A, ARG66A, ARG66F, ARG76A, ARG76F, ASN114A, ASN114F, ASP73A, ASP73F, GLU110A, GLU110F, GLU143A, GLU143F, GLU149A, GLU149F, GLU69A, GLU69F, LEU146A, LEU146F, LYS125A, LYS125F, LYS156A, LYS156F, THR68A, THR68F
• B-C: ALA119C, ALA123C, ALA128C, ALA271B, ALA286B, ALA324B, ALA425B, ALA430B, ALA434B, ALA468B, ALA475B, ALA480B, ALA481B, ALA501B, ALA63C, ALA67C, ARG118C, ARG17C, ARG273B, ARG408B, ARG471B, ARG497B, ARG510B, ARG513B, ARG66C, ARG76C, ASN114C, ASN257C, ASN258C, ASN284B, ASN476B, ASN57C, ASP269B, ASP272B, ASP285B, ASP426B, ASP487B, ASP488B, ASP494B, ASP80C, GLN280B, GLU10C, GLU121C, GLU14C, GLU15C, GLU260C, GLU279B, GLU435B, GLU482B, GLU491B, GLU504B, GLU511B, GLU58C, GLY127C, GLY277B, GLY424B, GLY484B, GLY502B, GLY54C, GLY79C, GLY85C, GLY87C, GLY91C, ILE13C, ILE165C, ILE281B, ILE403B, ILE490B, ILE499B, ILE59C, LEU122C, LEU124C, LEU12C, LEU16C, LEU19C, LEU427B, LEU485B, LEU503B, LEU506B, LYS115C, LYS11C, LYS125C, LYS20C, LYS22C, LYS402B, LYS421B, LYS472B, LYS483B, LYS493B, LYS507B, LYS509B, LYS55C, LYS6C, LYS88C, MET259C, MET505B, MET60C, PHE56C, PHE62C, PHE77C, PHE95C, PRO283B, PRO401B, PRO432B, PRO477B, PRO492B, PRO7C, PRO8C, SER256C, SER422B, THR111C, THR276B, THR399B, THR433B, THR508B, THR61C, THR64C, THR65C, THR93C, TRP431B, TRP479B, TRP86C, TYR24C, TYR429B, TYR478B, TYR512B, TYR78C, VAL126C, VAL164C, VAL278B, VAL282B, VAL428B, VAL486B, VAL489B, VAL498B, VAL500B, VAL94C, VAL9C
• B-D: ALA145D, ALA67B, ALA67D, ARG118B, ARG118D, ARG66B, ARG66D, ARG76B, ARG76D, ASN114B, ASN114D, ASP73B, ASP73D, GLU110B, GLU110D, GLU143B, GLU143D, GLU149B, GLU149D, GLU69B, GLU69D, LEU146B, LEU146D, LYS125B, LYS125D, LYS156B, LYS156D, SER147D, THR111B, THR111D, THR68B, THR68D
• B-E: ALA113B, ALA139B, ALA139E, ALA145B, ALA145E, ALA153B, ALA153E, ALA161B, ALA161E, ALA175B, ALA175E, ALA176B, ALA176E, ALA179B, ALA179E, ALA184B, ALA184E, ALA313B, ALA313E, ALA347B, ALA347E, ALA350B, ALA350E, ALA351B, ALA351E, ALA359B, ALA359E, ALA389B, ALA389E, ALA394B, ALA394E, ALA396B, ALA396E, ALA398B, ALA398E, ALA414B, ALA414E, ALA417B, ALA417E, ALA425B, ALA425E, ALA437B, ALA437E, ALA444B, ALA444E, ALA480B, ALA480E, ALA481B, ALA481E, ALA67B, ALA67E, ARG140B, ARG140E, ARG352B, ARG352E, ARG355B, ARG355E, ARG386B, ARG386E, ARG446B, ARG446E, ARG450E, ARG466B, ARG466E, ARG510B, ARG510E, ARG513B, ARG513E, ARG66B, ARG66E, ASN114B, ASN158B, ASN158E, ASN258B, ASN258E, ASN361B, ASN361E, ASN476B, ASN476E, ASN520B, ASN520E, ASP187B, ASP187E, ASP219B, ASP219E, ASP343B, ASP345B, ASP345E, ASP348B, ASP348E, ASP358B, ASP358E, ASP378B, ASP378E, CYS357B, CYS357E, GLN142B, GLN142E, GLN167B, GLN167E, GLN218B, GLN218E, GLN379B, GLN379E, GLN465B, GLU110B, GLU110E, GLU121B, GLU121E, GLU143B, GLU143E, GLU149B, GLU149E, GLU205B, GLU205E, GLU213B, GLU213E, GLU214E, GLU380B, GLU380E, GLU397B, GLU397E, GLU442B, GLU442E, GLU469B, GLU469E, GLU482B, GLU482E, GLU511B, GLU511E, GLU69B, GLU69E, GLY138B, GLY138E, GLY144B, GLY144E, GLY150B, GLY150E, GLY152B, GLY152E, GLY163B, GLY163E, GLY177B, GLY177E, GLY178B, GLY178E, GLY203B, GLY203E, GLY221B, GLY221E, GLY222B, GLY222E, GLY231B, GLY231E, GLY372B, GLY372E, GLY376B, GLY376E, GLY383B, GLY383E, GLY388B, GLY388E, GLY412B, GLY412E, GLY413B, GLY413E, GLY424B, GLY424E, GLY440B, GLY440E, GLY443B, GLY443E, GLY484B, GLY484E, GLY519B, GLY519E, HIS226B, HIS226E, HIS234B, HIS234E, HIS309B, HIS309E, HIS387B, HIS387E, HIS415B, HIS415E, HIS518B, HIS518E, ILE141B, ILE141E, ILE165B, ILE165E, ILE189B, ILE189E, ILE206B, ILE206E, ILE342B, ILE342E, ILE344B, ILE344E, ILE354B, ILE354E, ILE362B, ILE362E, ILE384B, ILE384E, ILE385B, ILE385E, ILE416B, ILE416E, ILE420B, ILE420E, ILE436B, ILE436E, ILE447B, ILE447E, ILE521B, ILE521E, LEU108B, LEU108E, LEU124B, LEU124E, LEU146B, LEU146E, LEU148B, LEU148E, LEU185B, LEU185E, LEU211B, LEU211E, LEU220B, LEU220E, LEU364B, LEU392B, LEU392E, LEU423B, LEU423E, LEU448B, LEU448E, LEU463E, LEU473B, LEU473E, LEU485B, LEU485E, LEU523B, LEU523E, LEU72E, LYS125B, LYS125E, LYS156B, LYS156E, LYS208E, LYS229B, LYS229E, LYS349B, LYS349E, LYS382B, LYS382E, LYS390B, LYS390E, LYS402B, LYS402E, LYS421B, LYS421E, LYS483B, LYS483E, LYS509B, LYS509E, LYS516B, LYS516E, LYS517B, LYS517E, MET157B, MET157E, MET160B, MET160E, MET171B, MET171E, MET191B, MET191E, MET199B, MET199E, MET259B, MET259E, MET391B, MET391E, PHE155B, PHE155E, PHE188B, PHE188E, PHE200B, PHE200E, PHE217B, PHE217E, PHE338B, PHE353B, PHE353E, PHE356B, PHE356E, PHE360B, PHE360E, PHE395B, PHE395E, PHE474B, PHE474E, PHE70B, PHE70E, PRO166E, PRO183B, PRO183E, PRO204B, PRO204E, PRO371B, PRO371E, PRO375B, PRO375E, PRO401B, PRO401E, PRO441B, PRO441E, PRO515B, PRO515E, PRO522B, PRO522E, SER107B, SER147B, SER147E, SER162B, SER162E, SER182B, SER182E, SER216B, SER216E, SER230B, SER230E, SER341B, SER341E, SER410B, SER410E, SER419B, SER419E, SER422B, SER422E, THR186B, THR186E, THR202B, THR202E, THR207B, THR207E, THR228B, THR228E, THR377B, THR377E, THR399B, THR399E, THR439B, THR439E, THR68B, THR68E, TRP312B, TRP312E, TRP479B, TRP479E, TYR120B, TYR120E, TYR151B, TYR151E, TYR181B, TYR181E, TYR198B, TYR373B, TYR373E, TYR381B, TYR381E, TYR393B, TYR393E, TYR411B, TYR411E, TYR449B, TYR449E, TYR470B, TYR470E, TYR512B, TYR512E, TYR514B, TYR514E, VAL117B, VAL117E, VAL154B, VAL154E, VAL159B, VAL159E, VAL164B, VAL164E, VAL180B, VAL180E, VAL201B, VAL201E, VAL209B, VAL209E, VAL210B, VAL210E, VAL215B, VAL215E, VAL224B, VAL225B, VAL225E, VAL232B, VAL232E, VAL233B, VAL233E, VAL374B, VAL374E, VAL400B, VAL400E, VAL428B, VAL428E, VAL438B, VAL438E, VAL445B, VAL445E, VAL486B, VAL486E
• B-F: ARG510B, ARG510F, ARG513B, ARG513F, GLU511B, GLU511F, PRO515B, PRO515F, TYR512B, TYR512F, TYR514B, TYR514F
• C-D: ARG510C, ARG510D, ARG513C, ARG513D, GLU511C, GLU511D, LYS509D, PRO515C, PRO515D, TYR512C, TYR512D, TYR514C, TYR514D
• C-E: ALA67C, ALA67E, ARG118C, ARG118E, ARG66C, ARG66E, ARG76E, ASN114C, ASN114E, ASP73C, ASP73E, GLU110C, GLU110E, GLU143C, GLU149C, GLU149E, GLU69C, GLU69E, LEU146C, LEU146E, LYS125C, LYS125E, LYS156C, LYS156E, THR68C, THR68E
• C-F: ALA123C, ALA123F, ALA139C, ALA139F, ALA145C, ALA145F, ALA153C, ALA153F, ALA161C, ALA161F, ALA175C, ALA175F, ALA176C, ALA176F, ALA179C, ALA179F, ALA184C, ALA184F, ALA313C, ALA313F, ALA347C, ALA347F, ALA350C, ALA350F, ALA351C, ALA351F, ALA359C, ALA359F, ALA389C, ALA389F, ALA394C, ALA394F, ALA396C, ALA396F, ALA398C, ALA398F, ALA414C, ALA414F, ALA417C, ALA417F, ALA425C, ALA425F, ALA437C, ALA437F, ALA444C, ALA444F, ALA480C, ALA480F, ALA481C, ALA481F, ALA67C, ALA67F, ARG140C, ARG140F, ARG352C, ARG352F, ARG355C, ARG355F, ARG386C, ARG386F, ARG446C, ARG446F, ARG450C, ARG466C, ARG466F, ARG510C, ARG510F, ARG513C, ARG513F, ARG66C, ARG66F, ASN158C, ASN158F, ASN258C, ASN258F, ASN361C, ASN361F, ASN476C, ASN520C, ASN520F, ASP187C, ASP187F, ASP219F, ASP343C, ASP345C, ASP345F, ASP348C, ASP348F, ASP358C, ASP358F, ASP378C, ASP378F, CYS357C, CYS357F, GLN142C, GLN142F, GLN167C, GLN167F, GLN218F, GLN379C, GLN379F, GLU110C, GLU110F, GLU121C, GLU121F, GLU143C, GLU143F, GLU149C, GLU149F, GLU205C, GLU205F, GLU213C, GLU213F, GLU380C, GLU380F, GLU397C, GLU397F, GLU442C, GLU442F, GLU469C, GLU469F, GLU482C, GLU482F, GLU511C, GLU511F, GLU69C, GLU69F, GLY105F, GLY127C, GLY127F, GLY137F, GLY138C, GLY138F, GLY144C, GLY144F, GLY150C, GLY150F, GLY152C, GLY152F, GLY163C, GLY163F, GLY177C, GLY177F, GLY178C, GLY178F, GLY203C, GLY203F, GLY221C, GLY221F, GLY222C, GLY222F, GLY231C, GLY231F, GLY372C, GLY372F, GLY376C, GLY376F, GLY383C, GLY383F, GLY388C, GLY388F, GLY412C, GLY412F, GLY413C, GLY413F, GLY424C, GLY424F, GLY440C, GLY440F, GLY443C, GLY443F, GLY484C, GLY484F, GLY519C, GLY519F, HIS226C, HIS226F, HIS234C, HIS234F, HIS309C, HIS309F, HIS387C, HIS387F, HIS415C, HIS415F, HIS518C, HIS518F, ILE141C, ILE141F, ILE165C, ILE165F, ILE189C, ILE189F, ILE206C, ILE206F, ILE342C, ILE342F, ILE344C, ILE344F, ILE354C, ILE354F, ILE362C, ILE362F, ILE384C, ILE384F, ILE385C, ILE385F, ILE416C, ILE416F, ILE420C, ILE420F, ILE436C, ILE436F, ILE447C, ILE447F, ILE521C, ILE521F, LEU108C, LEU108F, LEU122C, LEU122F, LEU124C, LEU124F, LEU146C, LEU146F, LEU148C, LEU148F, LEU185C, LEU185F, LEU211C, LEU211F, LEU220C, LEU220F, LEU392C, LEU392F, LEU423C, LEU423F, LEU448C, LEU448F, LEU473C, LEU473F, LEU485C, LEU485F, LEU523C, LEU523F, LEU72C, LEU72F, LYS125C, LYS125F, LYS156C, LYS156F, LYS208C, LYS208F, LYS229C, LYS229F, LYS349C, LYS349F, LYS382C, LYS382F, LYS390C, LYS390F, LYS402C, LYS402F, LYS421C, LYS421F, LYS451C, LYS483C, LYS483F, LYS509C, LYS509F, LYS516C, LYS516F, LYS517C, LYS517F, MET157C, MET157F, MET160C, MET160F, MET171C, MET171F, MET191F, MET199C, MET199F, MET259C, MET259F, MET391C, MET391F, PHE155C, PHE155F, PHE188C, PHE188F, PHE200C, PHE200F, PHE217F, PHE353C, PHE353F, PHE356C, PHE356F, PHE360C, PHE360F, PHE395C, PHE395F, PHE474C, PHE474F, PHE70C, PHE70F, PRO166C, PRO166F, PRO183C, PRO183F, PRO204C, PRO204F, PRO371C, PRO371F, PRO375C, PRO375F, PRO401C, PRO401F, PRO441C, PRO441F, PRO515C, PRO515F, PRO522C, PRO522F, SER107C, SER107F, SER147C, SER147F, SER162C, SER162F, SER182C, SER182F, SER216F, SER230C, SER230F, SER341C, SER341F, SER410C, SER410F, SER422C, SER422F, THR186C, THR186F, THR202C, THR202F, THR207C, THR207F, THR228C, THR228F, THR377C, THR377F, THR399C, THR399F, THR439C, THR439F, THR68C, THR68F, TRP312C, TRP312F, TRP479C, TRP479F, TYR120C, TYR120F, TYR151C, TYR151F, TYR181C, TYR181F, TYR198C, TYR198F, TYR373C, TYR373F, TYR381C, TYR381F, TYR393C, TYR393F, TYR411C, TYR411F, TYR449C, TYR449F, TYR470C, TYR470F, TYR512C, TYR512F, TYR514C, TYR514F, VAL117C, VAL117F, VAL126C, VAL126F, VAL154C, VAL154F, VAL159C, VAL159F, VAL164C, VAL164F, VAL180C, VAL180F, VAL201C, VAL201F, VAL209C, VAL209F, VAL210C, VAL210F, VAL215C, VAL215F, VAL224C, VAL224F, VAL225C, VAL225F, VAL232C, VAL232F, VAL233C, VAL233F, VAL374C, VAL374F, VAL400C, VAL400F, VAL428C, VAL428F, VAL438C, VAL438F, VAL445C, VAL445F, VAL486C, VAL486F
• D-E: ALA119D, ALA123D, ALA128D, ALA425E, ALA430E, ALA434E, ALA480E, ALA481E, ALA501E, ALA63D, ALA67D, ARG118D, ARG17D, ARG273E, ARG471E, ARG497E, ARG510E, ARG513E, ARG66D, ARG76D, ASN114D, ASN257D, ASN284E, ASN476E, ASN57D, ASP272E, ASP285E, ASP426E, ASP487E, ASP488E, ASP494E, ASP80D, GLN280E, GLU10D, GLU121D, GLU14D, GLU15D, GLU260D, GLU279E, GLU482E, GLU491E, GLU504E, GLU511E, GLU58D, GLY127D, GLY277E, GLY424E, GLY484E, GLY502E, GLY79D, GLY85D, GLY87D, GLY91D, ILE13D, ILE281E, ILE403E, ILE420E, ILE490E, ILE499E, ILE59D, LEU122D, LEU124D, LEU12D, LEU16D, LEU19D, LEU427E, LEU485E, LEU503E, LEU506E, LYS115D, LYS11D, LYS125D, LYS20D, LYS402E, LYS421E, LYS472E, LYS483E, LYS493E, LYS507E, LYS509E, LYS55D, LYS6D, LYS88D, MET259D, MET505E, MET60D, PHE56D, PHE62D, PHE95D, PRO283E, PRO401E, PRO432E, PRO477E, PRO492E, PRO7D, PRO8D, SER256D, SER422E, THR111D, THR276E, THR399E, THR433E, THR508E, THR61D, THR64D, THR65D, THR93D, TRP431E, TRP479E, TRP86D, TYR24D, TYR429E, TYR478E, TYR512E, TYR78D, VAL126D, VAL278E, VAL282E, VAL428E, VAL486E, VAL489E, VAL498E, VAL500E, VAL94D, VAL9D
• D-F: ALA123F, ALA128F, ALA286D, ALA425D, ALA430D, ALA434D, ALA468D, ALA475D, ALA480D, ALA481D, ALA501D, ALA63F, ARG118F, ARG17F, ARG273D, ARG408D, ARG471D, ARG497D, ARG510D, ARG513D, ARG66F, ARG76F, ASN114F, ASN257F, ASN258F, ASN284D, ASN476D, ASN57F, ASP272D, ASP285D, ASP426D, ASP487D, ASP488D, ASP494D, ASP80F, GLN280D, GLU10F, GLU121F, GLU14F, GLU15F, GLU260F, GLU279D, GLU435D, GLU482D, GLU491D, GLU504D, GLU511D, GLU58F, GLY127F, GLY424D, GLY484D, GLY502D, GLY79F, GLY85F, GLY87F, GLY91F, ILE13F, ILE165F, ILE281D, ILE403D, ILE420D, ILE490D, ILE499D, ILE59F, LEU122F, LEU124F, LEU12F, LEU16F, LEU19F, LEU427D, LEU485D, LEU503D, LEU506D, LYS115F, LYS11F, LYS125F, LYS20F, LYS288D, LYS402D, LYS421D, LYS472D, LYS483D, LYS493D, LYS507D, LYS509D, LYS55F, LYS6F, LYS88F, MET259F, MET505D, MET60F, PHE62F, PHE77F, PHE95F, PRO283D, PRO401D, PRO432D, PRO477D, PRO492D, PRO7F, PRO8F, SER256F, SER422D, THR111F, THR276D, THR399D, THR433D, THR508D, THR61F, THR64F, THR65F, THR93F, TRP431D, TRP479D, TRP86F, TYR24F, TYR429D, TYR478D, TYR512D, TYR78F, VAL126F, VAL164F, VAL278D, VAL282D, VAL400D, VAL428D, VAL486D, VAL489D, VAL498D, VAL500D, VAL94F, VAL9F
• E-F: ALA119E, ALA123E, ALA128E, ALA286F, ALA425F, ALA430F, ALA434F, ALA475F, ALA480F, ALA481F, ALA501F, ALA63E, ALA67E, ARG118E, ARG17E, ARG273F, ARG497F, ARG510F, ARG513F, ARG66E, ARG76E, ARG92E, ASN114E, ASN257E, ASN258E, ASN284F, ASN476F, ASN57E, ASP285F, ASP426F, ASP487F, ASP488F, ASP494F, ASP80E, GLN18E, GLN280F, GLU10E, GLU121E, GLU14E, GLU15E, GLU21E, GLU260E, GLU279F, GLU482F, GLU491F, GLU504F, GLU511F, GLU58E, GLY127E, GLY277F, GLY424F, GLY484F, GLY502F, GLY79E, GLY85E, GLY87E, GLY91E, ILE13E, ILE165E, ILE281F, ILE403F, ILE420F, ILE490F, ILE499F, ILE59E, LEU122E, LEU124E, LEU12E, LEU16E, LEU19E, LEU427F, LEU485F, LEU503F, LEU506F, LYS115E, LYS11E, LYS125E, LYS20E, LYS402F, LYS421F, LYS472F, LYS483F, LYS493F, LYS507F, LYS509F, LYS55E, LYS6E, LYS88E, MET157E, MET160E, MET259E, MET505F, MET60E, PHE62E, PHE77E, PHE95E, PRO283F, PRO401F, PRO432F, PRO477F, PRO492F, PRO7E, PRO8E, SER256E, SER422F, THR111E, THR276F, THR399F, THR433F, THR508F, THR61E, THR64E, THR65E, THR84E, THR93E, TRP431F, TRP479F, TRP86E, TYR24E, TYR429F, TYR478F, TYR512F, TYR78E, VAL126E, VAL164E, VAL278F, VAL282F, VAL428F, VAL486F, VAL489F, VAL498F, VAL500F, VAL94E, VAL9E