1WX0

crystal structure of transaldolase from thermus thermophilus hb8

• Total interactions analyzed: 45
• Total true interactions: 25
• Strongest Interaction:
  • Chains: D-H
  • Int. Res.: 62
  • Norm. En. per Res.: -3.7242
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-51.2989	-21.7336	-330.378	-403.4104	112	9	9	13576	6	24	15
A-E	-32.0097	-17.9184	-337.009	-386.9371	113	12	8	14103	6	24	16
A-F	-12.1311	-45.663	-150.904	-208.6982	62	5	0	5992	0	50	41
A-G	0.0	0.0	-16.1287	-16.1287	12	0	0	899	0	2	2
A-J	0.0	25.7363	-83.8213	-58.085	51	0	0	3033	0	4	15
B-C	-48.096	-18.5241	-327.454	-394.0741	113	12	9	13598	6	24	16
B-F	0.0	0.0	-16.0306	-16.0306	13	0	0	893	0	2	2
B-I	0.0	18.0069	-83.2405	-65.2336	50	3	0	3015	0	4	14
B-J	-10.2106	-57.7092	-162.891	-230.8108	62	6	0	6431	0	52	43
C-D	-38.3246	-9.5924	-330.592	-378.5091	111	10	10	13702	5	23	16
C-H	0.0	18.0716	-78.0757	-60.0041	47	3	0	2888	0	4	13
C-I	-19.9639	-54.0245	-157.855	-231.8435	63	2	0	6270	0	53	43
C-J	0.0	0.0	-19.4315	-19.4315	15	0	0	1023	0	3	2
D-E	-46.9678	-16.621	-326.425	-390.0138	110	13	9	13458	5	23	14
D-G	-2.7286	23.49	-80.7083	-59.947	47	2	0	2819	0	4	14
D-H	-9.6671	-54.977	-166.259	-230.9031	62	4	0	6425	0	50	41
D-I	0.0	0.0	-17.4659	-17.4659	12	0	0	946	0	3	2
E-F	0.0	27.2503	-77.079	-49.8287	45	5	0	2865	0	4	15
E-G	-10.7175	-33.5774	-141.822	-186.1169	61	5	0	5718	0	47	40
E-H	0.0	0.0	-14.0787	-14.0787	12	1	0	849	0	2	2
F-G	-28.4318	-14.2678	-320.858	-363.5576	108	12	9	13170	5	24	14
F-J	-28.7427	-12.9313	-344.74	-386.414	110	9	12	13849	6	22	13
G-H	-36.8562	-19.9845	-319.797	-376.6377	114	10	9	13549	6	23	15
H-I	-53.6508	-14.7324	-333.448	-401.8312	112	15	9	13807	6	24	15
I-J	-53.0088	-19.3496	-339.337	-411.6955	112	12	8	13837	6	24	17

Interface residues

• A-B: ALA102A, ALA121A, ALA124A, ALA127A, ALA128A, ALA130A, ALA132A, ALA17B, ALA183B, ALA184B, ALA188B, ALA18B, ALA191B, ALA69A, ALA72A, ARG105A, ARG129A, ARG141A, ARG14B, ARG154A, ARG178B, ASN122A, ASP143A, ASP144A, ASP164A, ASP189B, ASP208B, CYS103A, GLN123A, GLN161A, GLN161B, GLN163A, GLN200B, GLU151A, GLU155A, GLU158A, GLU15B, GLU182B, GLU2B, GLU66A, GLU97A, GLU98A, GLY131A, GLY140A, GLY187B, GLY20B, GLY210B, GLY99A, HIS176B, HIS179B, HIS195B, HIS204B, ILE118A, ILE145A, ILE156A, ILE160A, ILE16B, ILE190B, ILE209B, LEU100A, LEU117A, LEU125A, LEU126A, LEU139A, LEU152A, LEU153B, LEU165A, LEU185B, LEU186B, LEU201B, LEU202B, LEU206B, LEU211B, LEU22B, LEU3B, LEU70A, LEU93A, LYS101A, LYS104A, LYS168B, LYS199B, LYS203B, MET115A, MET159A, MET193B, MET1B, MET75A, PHE119A, PHE138A, PHE198B, PRO166A, PRO177B, PRO205B, PRO94A, SER107A, SER120A, SER23B, THR116A, THR181B, THR207B, THR68A, THR95A, THR96A, TRP147A, TRP19B, VAL142A, VAL157A, VAL157B, VAL162A, VAL180B, VAL197B, VAL21B
• A-E: ALA102E, ALA121E, ALA124E, ALA127E, ALA128E, ALA130E, ALA132E, ALA17A, ALA183A, ALA184A, ALA188A, ALA18A, ALA191A, ALA69E, ALA72E, ARG105E, ARG129E, ARG141E, ARG14A, ARG154E, ARG175E, ARG178A, ASN122E, ASP143E, ASP144E, ASP164E, ASP189A, ASP208A, CYS103E, GLN123E, GLN161A, GLN161E, GLN163E, GLN200A, GLU151E, GLU155E, GLU158E, GLU15A, GLU182A, GLU2A, GLU66E, GLU97E, GLU98E, GLY131E, GLY140E, GLY187A, GLY20A, GLY210A, GLY99E, HIS176A, HIS179A, HIS195A, HIS204A, ILE118E, ILE145E, ILE156E, ILE160E, ILE16A, ILE190A, ILE209A, LEU100E, LEU117E, LEU125E, LEU126E, LEU139E, LEU152E, LEU153A, LEU165E, LEU185A, LEU186A, LEU201A, LEU202A, LEU206A, LEU211A, LEU22A, LEU3A, LEU70E, LYS101E, LYS104E, LYS168A, LYS199A, LYS203A, MET115E, MET159E, MET193A, MET1A, MET75E, PHE119E, PHE138E, PHE198A, PRO166E, PRO177A, PRO205A, PRO94E, SER120E, SER23A, THR116E, THR181A, THR207A, THR58A, THR95E, THR96E, TRP147E, TRP19A, TYR4A, VAL142E, VAL157A, VAL157E, VAL162E, VAL180A, VAL197A, VAL21A, VAL59A
• A-F: ARG141A, ARG141F, ARG175A, ARG175F, ARG178A, ARG178F, ASP143A, ASP143F, ASP144A, ASP144F, ASP148A, ASP148F, ASP208A, ASP208F, GLN200A, GLN200F, GLU151A, GLU151F, GLU182A, GLU182F, GLY140A, GLY140F, GLY149A, GLY149F, GLY150A, GLY150F, HIS176A, HIS176F, HIS179A, HIS179F, HIS204A, HIS204F, ILE145A, ILE145F, LEU139A, LEU139F, LEU185A, LEU185F, LEU201A, LEU201F, LEU202A, LEU202F, LEU206A, LEU206F, LYS203A, LYS203F, PRO177A, PRO177F, PRO205A, PRO205F, SER146A, SER146F, THR181A, THR181F, THR207A, THR207F, TRP147A, TRP147F, VAL142A, VAL142F, VAL180A, VAL180F
• A-G: ASP208A, ASP208G, HIS204A, HIS204G, ILE209A, ILE209G, LEU206A, LEU206G, PRO205A, PRO205G, THR207A, THR207G
• A-J: ALA121A, ALA121J, ALA124A, ALA124J, ARG154A, ARG154J, ASN122A, ASN122J, ASP143A, ASP143J, ASP144A, ASP144J, ASP148A, ASP148J, GLN123A, GLN123J, GLU151A, GLU151J, GLU155A, GLU155J, GLY149A, GLY149J, GLY150A, GLY150J, ILE118A, ILE118J, ILE145A, ILE145J, ILE156A, ILE156J, LEU126A, LEU139A, LEU139J, LEU152A, LEU152J, LEU153A, LEU153J, PHE119A, PHE119J, PHE138A, PHE138J, PRO137A, PRO137J, SER120A, SER120J, SER146A, SER146J, TRP147A, TRP147J, VAL142A, VAL142J
• B-C: ALA102B, ALA121B, ALA124B, ALA127B, ALA128B, ALA130B, ALA132B, ALA17C, ALA183C, ALA184C, ALA188C, ALA18C, ALA191C, ALA69B, ALA72B, ARG105B, ARG129B, ARG141B, ARG14C, ARG154B, ARG175B, ARG178C, ASN122B, ASP143B, ASP144B, ASP164B, ASP189C, ASP208C, CYS103B, GLN123B, GLN161B, GLN161C, GLN163B, GLN200C, GLU151B, GLU155B, GLU158B, GLU15C, GLU182C, GLU2C, GLU66B, GLU97B, GLU98B, GLY131B, GLY140B, GLY187C, GLY20C, GLY210C, GLY99B, HIS176C, HIS179C, HIS195C, HIS204C, ILE118B, ILE145B, ILE156B, ILE160B, ILE16C, ILE174C, ILE190C, ILE209C, LEU100B, LEU117B, LEU125B, LEU126B, LEU152B, LEU153C, LEU165B, LEU185C, LEU186C, LEU201C, LEU202C, LEU206C, LEU211C, LEU22C, LEU3C, LEU70B, LEU93B, LYS101B, LYS104B, LYS199C, LYS203C, MET115B, MET159B, MET193C, MET1C, MET75B, PHE119B, PHE138B, PHE198C, PRO166B, PRO177C, PRO205C, PRO94B, SER107B, SER120B, SER146B, SER23C, THR116B, THR181C, THR207C, THR68B, THR95B, THR96B, TRP147B, TRP19C, VAL142B, VAL157B, VAL157C, VAL162B, VAL180C, VAL197C, VAL21C
• B-F: ASP208B, ASP208F, HIS204B, HIS204F, ILE209B, ILE209F, LEU206B, LEU206F, LYS203F, PRO205B, PRO205F, THR207B, THR207F
• B-I: ALA121B, ALA121I, ALA124B, ARG154B, ARG154I, ASN122B, ASN122I, ASP143B, ASP143I, ASP144B, ASP144I, ASP148B, ASP148I, GLN123B, GLN123I, GLU151B, GLU151I, GLU155B, GLU155I, GLY149B, GLY149I, GLY150B, GLY150I, ILE118B, ILE118I, ILE145B, ILE145I, ILE156B, ILE156I, LEU126I, LEU139B, LEU139I, LEU152B, LEU152I, LEU153B, LEU153I, PHE119B, PHE119I, PHE138B, PHE138I, PRO137B, PRO137I, SER120B, SER120I, SER146B, SER146I, TRP147B, TRP147I, VAL142B, VAL142I
• B-J: ARG141B, ARG141J, ARG175B, ARG175J, ARG178B, ARG178J, ASP143B, ASP143J, ASP144B, ASP144J, ASP148B, ASP148J, ASP208B, GLN200B, GLN200J, GLU151B, GLU151J, GLU182B, GLU182J, GLY140B, GLY140J, GLY149B, GLY149J, GLY150B, GLY150J, HIS176B, HIS176J, HIS179B, HIS179J, HIS204B, HIS204J, ILE145B, ILE145J, LEU139B, LEU139J, LEU185B, LEU201B, LEU201J, LEU202B, LEU202J, LEU206B, LEU206J, LYS203B, LYS203J, PRO177B, PRO177J, PRO205B, PRO205J, SER146B, SER146J, THR181B, THR181J, THR207B, THR207J, TRP147B, TRP147J, VAL142B, VAL142J, VAL180B, VAL180J, VAL197B, VAL197J
• C-D: ALA102C, ALA121C, ALA124C, ALA127C, ALA128C, ALA130C, ALA132C, ALA17D, ALA183D, ALA184D, ALA188D, ALA18D, ALA191D, ALA69C, ALA72C, ARG105C, ARG129C, ARG141C, ARG14D, ARG154C, ARG178D, ASN122C, ASP143C, ASP144C, ASP164C, ASP189D, ASP208D, CYS103C, GLN123C, GLN161C, GLN161D, GLN163C, GLN200D, GLU151C, GLU155C, GLU158C, GLU15D, GLU182D, GLU2D, GLU66C, GLU97C, GLU98C, GLY131C, GLY140C, GLY187D, GLY20D, GLY210D, GLY99C, HIS176D, HIS179D, HIS195D, HIS204D, ILE118C, ILE145C, ILE156C, ILE160C, ILE16D, ILE174D, ILE190D, ILE209D, LEU100C, LEU117C, LEU125C, LEU126C, LEU139C, LEU152C, LEU153D, LEU165C, LEU185D, LEU186D, LEU201D, LEU202D, LEU206D, LEU211D, LEU22D, LEU3D, LEU70C, LEU93C, LYS101C, LYS104C, LYS199D, LYS203D, MET115C, MET159C, MET193D, MET1D, MET75C, PHE119C, PHE138C, PHE198D, PRO177D, PRO205D, PRO94C, SER120C, SER23D, THR116C, THR181D, THR207D, THR68C, THR95C, THR96C, TRP147C, TRP19D, VAL142C, VAL157C, VAL157D, VAL162C, VAL180D, VAL197D, VAL21D, VAL67C
• C-H: ALA121C, ALA121H, ALA124C, ALA124H, ARG141C, ARG154C, ARG154H, ASN122C, ASN122H, ASP143C, ASP143H, ASP144C, ASP144H, ASP148C, ASP148H, GLN123C, GLN123H, GLU151C, GLU151H, GLU155C, GLU155H, GLY149C, GLY149H, GLY150H, ILE118C, ILE118H, ILE145C, ILE145H, ILE156H, LEU126H, LEU139H, LEU152C, LEU152H, LEU153H, PHE119C, PHE119H, PHE138C, PHE138H, PRO137H, SER120C, SER120H, SER146C, SER146H, TRP147C, TRP147H, VAL142C, VAL142H
• C-I: ARG141C, ARG141I, ARG175C, ARG175I, ARG178C, ARG178I, ASP143C, ASP143I, ASP144C, ASP144I, ASP148C, ASP148I, ASP208C, ASP208I, GLN200C, GLN200I, GLU151C, GLU151I, GLU182C, GLU182I, GLY140C, GLY140I, GLY149C, GLY149I, GLY150C, GLY150I, HIS176C, HIS176I, HIS179C, HIS179I, HIS204C, HIS204I, ILE145C, ILE145I, LEU139C, LEU139I, LEU185C, LEU185I, LEU201C, LEU201I, LEU202C, LEU202I, LEU206C, LEU206I, LYS203C, LYS203I, PRO177C, PRO177I, PRO205C, PRO205I, SER146C, SER146I, THR181C, THR181I, THR207C, THR207I, TRP147C, TRP147I, VAL142C, VAL142I, VAL180C, VAL180I, VAL197C
• C-J: ASP208C, ASP208J, GLN200J, HIS204C, HIS204J, ILE209C, ILE209J, LEU206C, LEU206J, LYS203C, LYS203J, PRO205C, PRO205J, THR207C, THR207J
• D-E: ALA102D, ALA121D, ALA124D, ALA127D, ALA128D, ALA130D, ALA132D, ALA17E, ALA183E, ALA184E, ALA188E, ALA18E, ALA191E, ALA69D, ARG105D, ARG129D, ARG141D, ARG14E, ARG154D, ARG178E, ASN122D, ASP143D, ASP144D, ASP164D, ASP189E, ASP208E, CYS103D, GLN123D, GLN161D, GLN161E, GLN163D, GLN200E, GLU155D, GLU158D, GLU15E, GLU182E, GLU2E, GLU66D, GLU97D, GLU98D, GLY131D, GLY140D, GLY187E, GLY20E, GLY210E, GLY99D, HIS176E, HIS179E, HIS195E, HIS204E, ILE118D, ILE145D, ILE156D, ILE160D, ILE16E, ILE190E, ILE209E, LEU100D, LEU117D, LEU125D, LEU126D, LEU139D, LEU152D, LEU153E, LEU165D, LEU185E, LEU186E, LEU201E, LEU202E, LEU206E, LEU211E, LEU22E, LEU3E, LEU70D, LEU93D, LYS101D, LYS104D, LYS168E, LYS199E, LYS203E, MET115D, MET159D, MET193E, MET1E, MET75D, PHE119D, PHE138D, PHE198E, PRO166D, PRO177E, PRO205E, PRO94D, SER120D, SER173D, SER23E, THR116D, THR181E, THR207E, THR68D, THR95D, THR96D, TRP147D, TRP19E, VAL142D, VAL157D, VAL157E, VAL162D, VAL180E, VAL197E, VAL21E
• D-G: ALA121D, ALA121G, ALA124G, ARG141D, ARG154D, ARG154G, ASN122D, ASN122G, ASP143D, ASP143G, ASP144D, ASP144G, ASP148D, ASP148G, GLN123D, GLN123G, GLU151D, GLU151G, GLU155D, GLU155G, GLY149D, GLY149G, GLY150G, ILE118D, ILE118G, ILE145D, ILE145G, ILE156G, LEU126D, LEU126G, LEU139G, LEU152D, LEU152G, LEU153G, PHE119D, PHE119G, PHE138D, PHE138G, PRO137G, SER120D, SER120G, SER146D, SER146G, TRP147D, TRP147G, VAL142D, VAL142G
• D-H: ARG141D, ARG141H, ARG175D, ARG175H, ARG178D, ARG178H, ASP143D, ASP143H, ASP144D, ASP144H, ASP148D, ASP148H, ASP208D, GLN200D, GLN200H, GLU151D, GLU151H, GLU182D, GLU182H, GLY140D, GLY140H, GLY149D, GLY149H, GLY150D, GLY150H, HIS176D, HIS176H, HIS179D, HIS179H, HIS204D, HIS204H, ILE145D, ILE145H, LEU139D, LEU139H, LEU185D, LEU185H, LEU201D, LEU201H, LEU202D, LEU202H, LEU206D, LEU206H, LYS203D, LYS203H, PRO177D, PRO177H, PRO205D, PRO205H, SER146D, SER146H, THR181D, THR181H, THR207D, THR207H, TRP147D, TRP147H, VAL142D, VAL142H, VAL180D, VAL180H, VAL197H
• D-I: ASP208D, ASP208I, HIS204D, HIS204I, ILE209D, ILE209I, LEU206D, LEU206I, PRO205D, PRO205I, THR207D, THR207I
• E-F: ALA121E, ALA121F, ALA124E, ARG141F, ARG154E, ARG154F, ASN122E, ASN122F, ASP143E, ASP143F, ASP144E, ASP144F, ASP148E, ASP148F, GLN123E, GLN123F, GLU151E, GLU151F, GLU155E, GLU155F, GLY149E, GLY149F, GLY150E, ILE118E, ILE118F, ILE145E, ILE145F, LEU126E, LEU139E, LEU152E, LEU152F, LEU153E, PHE119E, PHE119F, PHE138E, PHE138F, PRO137E, SER120E, SER120F, SER146E, SER146F, TRP147E, TRP147F, VAL142E, VAL142F
• E-G: ARG141E, ARG141G, ARG175E, ARG175G, ARG178E, ARG178G, ASP143E, ASP143G, ASP144E, ASP144G, ASP148E, ASP148G, ASP208G, GLN200E, GLN200G, GLU151E, GLU151G, GLU182E, GLU182G, GLY140E, GLY140G, GLY149E, GLY149G, GLY150E, GLY150G, HIS176E, HIS176G, HIS179E, HIS179G, HIS204E, HIS204G, ILE145E, ILE145G, LEU139E, LEU139G, LEU185E, LEU185G, LEU201E, LEU201G, LEU202E, LEU202G, LEU206E, LEU206G, LYS203E, LYS203G, PRO177E, PRO177G, PRO205E, PRO205G, SER146E, SER146G, THR181E, THR181G, THR207E, THR207G, TRP147E, TRP147G, VAL142E, VAL142G, VAL180E, VAL180G
• E-H: ASP208E, ASP208H, HIS204E, HIS204H, ILE209E, ILE209H, LEU206E, LEU206H, PRO205E, PRO205H, THR207E, THR207H
• F-G: ALA102F, ALA121F, ALA124F, ALA127F, ALA128F, ALA130F, ALA132F, ALA171G, ALA17G, ALA183G, ALA184G, ALA188G, ALA18G, ALA191G, ALA69F, ALA72F, ARG105F, ARG129F, ARG141F, ARG154F, ARG175F, ARG178G, ASN122F, ASP143F, ASP144F, ASP164F, ASP189G, ASP208G, CYS103F, GLN123F, GLN161F, GLN161G, GLN163F, GLN200G, GLU155F, GLU158F, GLU15G, GLU182G, GLU2G, GLU97F, GLU98F, GLY131F, GLY140F, GLY187G, GLY20G, GLY210G, GLY99F, HIS176G, HIS179G, HIS204G, ILE118F, ILE145F, ILE156F, ILE160F, ILE16G, ILE190G, ILE209G, LEU100F, LEU117F, LEU125F, LEU126F, LEU152F, LEU153G, LEU165F, LEU185G, LEU186G, LEU201G, LEU202G, LEU206G, LEU211G, LEU22G, LEU3G, LEU70F, LEU93F, LYS101F, LYS104F, LYS168G, LYS199G, LYS203G, MET115F, MET159F, MET193G, MET1G, MET75F, PHE119F, PHE138F, PHE198G, PRO137F, PRO166F, PRO177G, PRO205G, PRO94F, SER120F, SER23G, THR116F, THR181G, THR207G, THR95F, THR96F, TRP147F, TRP19G, VAL142F, VAL157F, VAL157G, VAL162F, VAL180G, VAL197G, VAL21G
• F-J: ALA102J, ALA121J, ALA124J, ALA127J, ALA128J, ALA130J, ALA132J, ALA17F, ALA183F, ALA184F, ALA188F, ALA18F, ALA191F, ALA69J, ARG105J, ARG129J, ARG141J, ARG14F, ARG154J, ARG178F, ASN122J, ASP143J, ASP144J, ASP164J, ASP189F, ASP208F, CYS103J, GLN123J, GLN161F, GLN161J, GLN163J, GLN200F, GLU155J, GLU158J, GLU15F, GLU182F, GLU2F, GLU66J, GLU97J, GLU98J, GLY131J, GLY140J, GLY187F, GLY20F, GLY210F, GLY99J, HIS176F, HIS179F, HIS195F, HIS204F, ILE118J, ILE145J, ILE156J, ILE160J, ILE16F, ILE190F, ILE209F, LEU100J, LEU117J, LEU125J, LEU126J, LEU152J, LEU153F, LEU165J, LEU185F, LEU186F, LEU201F, LEU202F, LEU206F, LEU211F, LEU22F, LEU3F, LEU70J, LEU93J, LYS101J, LYS104J, LYS168F, LYS199F, LYS203F, MET115J, MET159J, MET193F, MET1F, MET75J, PHE119J, PHE138J, PHE198F, PRO177F, PRO205F, PRO94J, SER107J, SER120J, SER146J, SER23F, THR116J, THR181F, THR207F, THR68J, THR95J, THR96J, TRP147J, TRP19F, VAL142J, VAL157F, VAL157J, VAL162J, VAL180F, VAL197F, VAL21F, VAL67J
• G-H: ALA102G, ALA121G, ALA124G, ALA127G, ALA128G, ALA130G, ALA132G, ALA17H, ALA183H, ALA184H, ALA188H, ALA18H, ALA191H, ALA69G, ARG105G, ARG129G, ARG141G, ARG14H, ARG154G, ARG175G, ARG178H, ASN122G, ASP143G, ASP144G, ASP164G, ASP189H, ASP208H, CYS103G, GLN123G, GLN161G, GLN161H, GLN163G, GLN200H, GLU151G, GLU155G, GLU158G, GLU15H, GLU182H, GLU2H, GLU66G, GLU97G, GLU98G, GLY131G, GLY140G, GLY187H, GLY20H, GLY210H, GLY99G, HIS176H, HIS179H, HIS195H, HIS204H, ILE118G, ILE145G, ILE156G, ILE160G, ILE16H, ILE174H, ILE190H, ILE209H, LEU100G, LEU117G, LEU125G, LEU126G, LEU139G, LEU152G, LEU153H, LEU165G, LEU185H, LEU186H, LEU201H, LEU202H, LEU206H, LEU211H, LEU22H, LEU3H, LEU70G, LEU93G, LYS101G, LYS104G, LYS168H, LYS199H, LYS203H, MET115G, MET159G, MET193H, MET1H, MET75G, PHE119G, PHE138G, PHE198H, PRO166G, PRO177H, PRO205H, PRO94G, SER120G, SER146G, SER173G, SER23H, THR116G, THR181H, THR207H, THR95G, THR96G, TRP147G, TRP19H, TYR4H, VAL142G, VAL157G, VAL157H, VAL162G, VAL180H, VAL197H, VAL21H
• H-I: ALA102H, ALA121H, ALA124H, ALA127H, ALA128H, ALA130H, ALA132H, ALA17I, ALA183I, ALA184I, ALA188I, ALA18I, ALA191I, ALA69H, ALA72H, ARG105H, ARG129H, ARG141H, ARG14I, ARG154H, ARG178I, ASN122H, ASP143H, ASP144H, ASP164H, ASP189I, ASP208I, CYS103H, GLN123H, GLN161H, GLN161I, GLN163H, GLN200I, GLU151H, GLU155H, GLU158H, GLU15I, GLU182I, GLU2I, GLU66H, GLU97H, GLU98H, GLY131H, GLY140H, GLY187I, GLY20I, GLY210I, GLY99H, HIS176I, HIS179I, HIS195I, HIS204I, ILE118H, ILE145H, ILE156H, ILE160H, ILE16I, ILE174I, ILE190I, ILE209I, LEU100H, LEU117H, LEU125H, LEU126H, LEU152H, LEU153I, LEU165H, LEU185I, LEU186I, LEU201I, LEU202I, LEU206I, LEU211I, LEU22I, LEU3I, LEU70H, LEU93H, LYS101H, LYS104H, LYS199I, LYS203I, MET115H, MET159H, MET193I, MET1I, MET75H, PHE119H, PHE138H, PHE198I, PRO166H, PRO177I, PRO205I, PRO94H, SER120H, SER23I, THR116H, THR181I, THR207I, THR68H, THR95H, THR96H, TRP147H, TRP19I, TYR4I, VAL142H, VAL157H, VAL157I, VAL162H, VAL180I, VAL197I, VAL21I, VAL67H
• I-J: ALA102I, ALA121I, ALA124I, ALA127I, ALA128I, ALA130I, ALA132I, ALA17J, ALA183J, ALA184J, ALA188J, ALA18J, ALA191J, ALA69I, ALA72I, ARG105I, ARG129I, ARG141I, ARG14J, ARG154I, ARG175I, ARG178J, ASN122I, ASP143I, ASP144I, ASP164I, ASP189J, ASP208J, CYS103I, GLN123I, GLN161I, GLN161J, GLN163I, GLN200J, GLU151I, GLU155I, GLU158I, GLU15J, GLU182J, GLU2J, GLU66I, GLU97I, GLU98I, GLY131I, GLY140I, GLY187J, GLY20J, GLY210J, GLY99I, HIS176J, HIS179J, HIS195J, HIS204J, ILE118I, ILE145I, ILE156I, ILE160I, ILE16J, ILE190J, ILE209J, LEU100I, LEU117I, LEU125I, LEU126I, LEU139I, LEU152I, LEU165I, LEU185J, LEU186J, LEU201J, LEU202J, LEU206J, LEU211J, LEU22J, LEU3J, LEU70I, LEU93I, LYS101I, LYS104I, LYS168J, LYS199J, LYS203J, MET115I, MET159I, MET193J, MET1J, MET75I, PHE119I, PHE138I, PHE198J, PRO166I, PRO177J, PRO205J, PRO94I, SER107I, SER120I, SER23J, THR116I, THR181J, THR207J, THR68I, THR95I, THR96I, TRP147I, TRP19J, VAL142I, VAL157I, VAL157J, VAL162I, VAL180J, VAL197J, VAL21J