1WWW

ngf in complex with domain 5 of the trka receptor

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: W-X
  • Int. Res.: 76
  • Norm. En. per Res.: -3.3794
• Hub Node: V(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
V-W	-76.9043	24.0639	-421.992	-474.8324	143	22	17	17522	0	24	38
V-X	-24.7765	0.0	-85.3967	-110.1732	46	4	1	3399	0	5	9
V-Y	-36.955	-49.0923	-163.637	-249.6844	74	11	1	6951	2	21	24
W-X	-32.6609	-39.8515	-184.319	-256.8314	76	16	1	7355	2	21	22
W-Y	-22.2928	0.0	-79.7057	-101.9985	45	5	1	3318	0	5	10

Interface residues

• V-W: ALA107V, ALA107W, ALA116W, ALA89V, ALA89W, ALA97V, ALA97W, ALA98V, ALA98W, ARG100V, ARG100W, ARG103V, ARG103W, ARG114V, ARG114W, ARG69V, ARG69W, ARG9V, ARG9W, ASN43V, ASN43W, ASN45V, ASN45W, ASN46V, ASN46W, ASN77V, ASN77W, ASP105V, ASP105W, ASP72V, ASP72W, CYS108V, CYS108W, CYS110V, CYS110W, CYS15V, CYS15W, CYS68V, CYS68W, CYS80W, GLN51V, GLN51W, GLU11V, GLU11W, GLU55V, GLU55W, GLY10V, GLY10W, GLY70V, GLY70W, HIS75V, HIS75W, HIS84V, HIS84W, HIS8V, HIS8W, ILE102V, ILE102W, ILE104V, ILE104W, ILE31V, ILE31W, ILE44V, ILE44W, ILE6V, ILE6W, ILE71V, ILE71W, LEU112V, LEU112W, LEU39V, LEU90V, LEU90W, LYS115V, LYS115W, LYS50V, LYS50W, LYS74V, LYS74W, LYS88V, LYS88W, PHE101V, PHE101W, PHE12V, PHE12W, PHE49V, PHE49W, PHE53V, PHE53W, PHE54V, PHE54W, PHE7V, PHE7W, PHE86V, PHE86W, SER113V, SER113W, SER13V, SER13W, SER17V, SER17W, SER19V, SER19W, SER47W, SER73V, SER73W, SER78V, SER78W, THR106V, THR106W, THR56V, THR56W, THR81V, THR81W, THR83V, THR83W, THR85V, THR85W, THR91V, TRP21V, TRP21W, TRP76V, TRP76W, TRP99V, TRP99W, TYR52V, TYR52W, TYR79V, TYR79W, VAL109V, VAL109W, VAL111V, VAL111W, VAL14V, VAL14W, VAL22V, VAL22W, VAL42V, VAL42W, VAL48V, VAL48W, VAL87V, VAL87W
• V-X: ALA107V, ALA28V, ARG103V, ARG347X, ASN349X, ASN355X, ASN381X, ASP105V, ASP30V, CYS110V, GLN350X, GLU35V, GLY33V, HIS297X, HIS298X, HIS353X, HIS84V, ILE104V, ILE31V, ILE328X, LEU112V, LEU348X, LYS32V, LYS34V, LYS88V, MET296X, MET379X, PHE101V, PHE327X, PHE86V, PRO351X, PRO382X, SER113V, SER326X, THR106V, THR29V, THR325X, THR352X, THR81V, THR82V, THR83V, THR85V, TYR79V, VAL109V, VAL111V, VAL354X
• V-Y: ALA107V, ALA293Y, ALA336Y, ARG342Y, ARG347Y, ARG59V, ARG69V, ARG9V, ASN356Y, ASN381Y, ASP16V, ASP24V, ASP380Y, CYS15V, CYS300Y, CYS345Y, GLN289Y, GLN350Y, GLU11V, GLU295Y, GLU331Y, GLU334Y, GLU339Y, GLU55V, GLY10V, GLY23V, GLY344Y, HIS291Y, HIS297Y, HIS298Y, HIS343Y, HIS353Y, HIS4V, HIS8V, ILE301Y, ILE6V, LEU290Y, LEU333Y, LEU346Y, LYS50V, MET296Y, MET379Y, PHE12V, PHE303Y, PHE332Y, PHE378Y, PHE54V, PHE7V, PRO302Y, PRO335Y, PRO351Y, PRO382Y, PRO5V, SER13V, SER17V, SER19V, SER2V, SER304Y, SER3V, THR106V, THR292Y, THR352Y, THR56V, TRP21V, TRP299Y, TYR52V, VAL14V, VAL18V, VAL20V, VAL22V, VAL294Y, VAL305Y, VAL341Y, VAL354Y
• W-X: ALA107W, ALA293X, ALA336X, ALA337X, ARG342X, ARG347X, ARG59W, ARG69W, ARG9W, ASN356X, ASN381X, ASP16W, ASP380X, CYS15W, CYS300X, CYS345X, GLN289X, GLN350X, GLU11W, GLU295X, GLU331X, GLU334X, GLU339X, GLU55W, GLY10W, GLY23W, GLY344X, HIS291X, HIS297X, HIS298X, HIS343X, HIS353X, HIS4W, HIS8W, ILE301X, ILE6W, LEU290X, LEU333X, LEU346X, LYS50W, MET296X, MET379X, PHE12W, PHE303X, PHE329X, PHE332X, PHE378X, PHE53W, PHE54W, PHE7W, PRO302X, PRO335X, PRO351X, PRO382X, PRO5W, SER13W, SER17W, SER19W, SER2W, SER304X, SER3W, THR106W, THR292X, THR352X, THR56W, TRP21W, TRP299X, TYR52W, VAL14W, VAL18W, VAL20W, VAL22W, VAL294X, VAL305X, VAL341X, VAL354X
• W-Y: ALA107W, ALA28W, ARG103W, ARG114W, ARG347Y, ASN349Y, ASN355Y, ASP105W, ASP30W, CYS108W, CYS110W, GLN350Y, GLU35W, GLY33W, HIS297Y, HIS298Y, HIS353Y, HIS84W, ILE104W, ILE31W, ILE328Y, LEU112W, LEU348Y, LYS32W, LYS34W, MET296Y, MET379Y, PHE101W, PHE327Y, PHE86W, PRO351Y, SER113W, SER326Y, THR106W, THR29W, THR325Y, THR352Y, THR81W, THR82W, THR83W, THR85W, TYR79W, VAL109W, VAL111W, VAL354Y