1WT5

the crystal structure of a humanized antibody fv 528

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 83
  • Norm. En. per Res.: -2.9284
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-40.4608	-40.4608	38	4	1	2558	0	3	0
A-C	-23.0055	9.6484	-229.7	-243.0571	83	4	6	8572	0	8	5
A-D	0.0	0.0	-25.535	-25.535	29	0	0	1358	0	7	3
B-C	0.0	0.0	-27.4773	-27.4773	29	0	0	1375	1	7	3
B-D	-16.6043	18.3285	-232.563	-230.8388	86	10	8	8693	0	8	5
C-D	0.0	0.0	-0.0099	-0.0099	2	0	0	1	0	0	0

Interface residues

• A-B: ALA40A, ALA40B, ALA92A, ALA92B, ALA9A, ALA9B, ASP89B, GLN39A, GLN39B, GLN43A, GLN43B, GLU10A, GLU10B, GLY42A, GLY42B, GLY44A, GLY44B, GLY8A, LEU113A, LEU113B, LYS12A, LYS12B, PRO41A, PRO41B, SER88A, SER88B, THR115A, THR115B, THR91A, THR91B, TYR95A, TYR95B, VAL114A, VAL114B, VAL11A, VAL11B, VAL93A, VAL93B
• A-C: ALA40A, ALA61A, ALA97A, ARG38A, ARG59C, ARG98A, ASN33C, ASN50A, ASN59A, ASP106A, ASP1C, ASP58C, CYS93C, CYS96A, GLN105C, GLN110A, GLN39A, GLN43A, GLN43C, GLN47C, GLN50C, GLN6A, GLN6C, GLN95C, GLU39C, GLU46A, GLU62A, GLY100A, GLY101A, GLY104C, GLY106C, GLY109A, GLY111A, GLY42A, GLY44A, GLY46C, GLY49A, GLY96C, HIS31C, HIS35A, HIS98C, ILE35C, ILE53C, ILE99C, LEU38C, LEU42C, LEU45A, LEU51C, LEU52C, LYS44C, LYS55C, LYS63A, MET48A, PHE103C, PHE104A, PHE105A, PHE60C, PHE94C, PRO100C, PRO101C, PRO102A, PRO49C, SER48C, SER61C, SER97C, SER99A, THR102C, THR36C, TRP108A, TRP36A, TRP47A, TYR103A, TYR107A, TYR37C, TYR41C, TYR54C, TYR60A, TYR91C, TYR92C, TYR95A, VAL37A, VAL90C, VAL93A
• A-D: ALA85D, ALA9A, GLN110A, GLN3A, GLN43D, GLN47D, GLN6A, GLU10A, GLU110D, GLU86D, GLY111A, GLY46D, GLY89D, GLY8A, ILE111D, ILE76A, LEU113A, LYS108D, LYS23A, LYS44D, PRO45D, SER21A, SER7A, THR112A, VAL11A, VAL5A, VAL88D, VAL90D, VAL93A
• B-C: ALA85C, ALA9B, GLN110B, GLN43C, GLN47C, GLN6B, GLU10B, GLU110C, GLU86C, GLY111B, GLY46C, GLY89C, GLY8B, ILE111C, LEU113B, LYS108C, LYS12B, LYS23B, LYS44C, PRO45C, SER21B, SER7B, THR112B, TYR92C, VAL11B, VAL5B, VAL88C, VAL90C, VAL93B
• B-D: ALA40B, ALA61B, ALA97B, ARG38B, ARG59D, ARG98B, ASN33D, ASN50B, ASN59B, ASP106B, ASP1D, ASP58D, CYS93D, CYS96B, GLN105D, GLN110B, GLN39B, GLN43B, GLN43D, GLN47D, GLN50D, GLN6B, GLN95D, GLU39D, GLU46B, GLU62B, GLY100B, GLY101B, GLY104D, GLY106D, GLY109B, GLY111B, GLY42B, GLY44B, GLY46D, GLY49B, GLY96D, HIS31D, HIS35B, HIS98D, ILE35D, ILE53D, ILE99D, LEU38D, LEU42D, LEU45B, LEU51D, LYS44D, LYS55D, LYS63B, MET48B, MET4D, PHE103D, PHE104B, PHE105B, PHE60D, PHE94D, PRO100D, PRO101D, PRO102B, PRO41B, PRO45D, PRO49D, SER48D, SER61D, SER97D, SER99B, THR102D, THR36D, TRP108B, TRP36B, TRP40D, TRP47B, TYR103B, TYR107B, TYR37D, TYR41D, TYR54D, TYR60B, TYR91D, TYR92D, TYR95B, VAL37B, VAL3D, VAL90D, VAL93B
• C-D: GLY46C, GLY46D