1WEK

crystal structure of the conserved hypothetical protein tt1465 from thermus thermophilus hb8

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 43
  • Norm. En. per Res.: -5.933
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-89.7121	34.2373	-675.1	-730.5748	215	42	16	28272	7	57	72
A-C	0.0	3.8872	-69.5929	-65.7057	26	1	0	2353	0	9	10
A-D	0.0	0.0	-0.0531	-0.0531	7	0	0	22	0	0	0
A-E	0.0	-8.6815	-55.9561	-64.6376	24	1	1	1995	1	11	13
A-F	-3.1102	-123.5844	-110.309	-237.0036	43	8	8	4547	7	26	16
B-C	-10.7387	-132.7247	-111.655	-255.1184	43	7	8	4422	8	23	16
B-D	0.0	-1.8218	-58.4442	-60.266	23	0	1	1966	0	10	14
B-E	0.0	0.0	-0.122	-0.122	7	0	0	41	0	0	0
B-F	0.0	6.6627	-65.3003	-58.6376	28	1	0	2412	0	10	10
C-D	-66.2473	6.0166	-782.271	-842.5017	218	37	27	31506	10	66	72
C-E	0.0	-0.0852	-64.8485	-64.9337	22	0	0	1854	0	10	9
C-F	0.0	0.0	-8.1867	-8.1867	9	0	0	339	0	0	0
D-E	-29.5148	-122.7886	-143.011	-295.3144	72	9	6	5746	18	28	22
D-F	0.0	-2.519	-61.4934	-64.0124	20	2	0	1725	0	8	9
E-F	-75.267	-0.1313	-759.722	-835.1202	219	32	23	31100	8	61	66

Interface residues

• A-B: ALA181A, ALA181B, ALA188A, ALA188B, ALA23A, ALA23B, ALA46A, ALA46B, ALA54A, ALA54B, ARG119A, ARG119B, ARG124A, ARG124B, ARG130A, ARG130B, ARG162A, ARG178A, ARG178B, ARG17A, ARG17B, ARG184A, ARG184B, ARG20A, ARG47A, ARG47B, ASP146A, ASP146B, ASP14A, ASP14B, ASP169A, ASP169B, ASP185A, ASP185B, ASP193A, ASP193B, ASP8A, ASP8B, GLN106A, GLN156A, GLN156B, GLN186A, GLN186B, GLN195A, GLN195B, GLN36A, GLN36B, GLN9A, GLN9B, GLU101A, GLU101B, GLU105A, GLU105B, GLU13A, GLU13B, GLU147A, GLU147B, GLU150A, GLU150B, GLU158A, GLU158B, GLU174A, GLU174B, GLU192A, GLU192B, GLU24A, GLU24B, GLU27A, GLU27B, GLU30A, GLU30B, GLU34A, GLU34B, GLY140A, GLY140B, GLY141A, GLY141B, GLY143A, GLY143B, GLY171A, GLY171B, GLY175A, GLY175B, GLY190A, GLY190B, GLY28A, GLY28B, GLY44B, HIS104A, HIS104B, HIS11A, HIS11B, HIS12A, HIS12B, HIS52A, HIS52B, ILE100A, ILE100B, ILE21A, ILE21B, LEU102A, LEU102B, LEU10A, LEU10B, LEU118A, LEU118B, LEU145A, LEU145B, LEU148A, LEU148B, LEU152A, LEU152B, LEU154A, LEU154B, LEU155A, LEU155B, LEU167A, LEU167B, LEU176A, LEU176B, LEU180A, LEU180B, LEU183A, LEU183B, LEU18A, LEU18B, LEU194A, LEU194B, LEU196A, LEU196B, LEU22A, LEU22B, LEU32A, LEU32B, LEU35A, LEU35B, LEU39A, LEU39B, LYS125A, LYS125B, LYS159A, LYS159B, LYS187A, LYS187B, PHE121A, PHE121B, PHE122A, PHE122B, PHE137A, PHE142A, PHE142B, PHE182A, PHE182B, PHE197A, PHE197B, PHE19A, PHE19B, PHE25A, PHE25B, PHE29A, PHE29B, PHE48A, PHE48B, PRO103A, PRO103B, PRO139A, PRO139B, PRO191A, PRO191B, PRO53A, PRO53B, SER149A, SER149B, SER15A, SER15B, SER33A, SER33B, SER45A, SER45B, THR144A, THR144B, THR157A, THR157B, THR31A, THR31B, TRP16A, TRP16B, TRP173A, TRP173B, TRP179A, TRP179B, TYR120A, TYR120B, TYR131A, TYR131B, TYR172A, TYR172B, VAL123A, VAL123B, VAL126A, VAL126B, VAL129A, VAL129B, VAL151A, VAL151B, VAL153A, VAL153B, VAL160A, VAL160B, VAL177A, VAL177B, VAL189A, VAL189B, VAL26A, VAL26B
• A-C: ALA23A, ARG17A, ARG17C, ARG20A, ASP14A, ASP14C, GLN9A, GLN9C, GLU13A, GLU13C, HIS11C, HIS12C, ILE21A, ILE7A, LEU10A, LEU10C, LEU18A, LEU22A, LEU6A, PHE19A, PHE19C, PRO5A, SER15A, SER15C, TRP16A, TRP16C
• A-D: ARG130D, LEU22A, LEU22D, LEU6A, PHE19A, PHE19D, VAL26A
• A-E: ARG17A, ARG17E, ARG20E, ASP14A, ASP14E, GLU13A, GLU13E, HIS11A, HIS11E, HIS12E, ILE21E, ILE7A, LEU10A, LEU18A, LEU18E, LEU22A, LEU22E, LEU6A, PHE19A, PHE19E, SER15A, SER15E, TRP16A, TRP16E
• A-F: ALA23A, ALA23F, ARG119A, ARG119F, ARG17A, ARG17F, ARG20A, ARG20F, ASP14F, GLN9F, GLU24A, GLU24F, GLU27A, GLU27F, GLU30A, GLU30F, GLU34A, GLY28A, GLY28F, ILE21A, ILE21F, LEU10F, LEU116A, LEU18A, LEU18F, LEU22A, LEU22F, LYS3F, PHE19A, PHE19F, PHE25A, PHE25F, PHE29A, SER15A, SER15F, THR31A, THR31F, TRP16A, TRP16F, TYR120A, TYR120F, VAL26A, VAL26F
• B-C: ALA115B, ALA23B, ALA23C, ARG119B, ARG119C, ARG17B, ARG17C, ARG20B, ARG20C, ASP14C, GLU101B, GLU24B, GLU24C, GLU27B, GLU27C, GLU30B, GLU30C, GLU34B, GLY28B, GLY28C, ILE21B, ILE21C, LEU116B, LEU18B, LEU18C, LEU22B, LEU22C, LYS3C, PHE19B, PHE19C, PHE25B, PHE25C, PHE29B, PHE29C, SER117B, SER15C, THR31B, THR31C, TRP16B, TRP16C, TYR120C, VAL26B, VAL26C
• B-D: ARG17B, ARG17D, ARG20B, ARG20D, ASP14B, ASP14D, GLU13D, HIS11B, HIS11D, HIS12D, ILE21D, ILE7B, LEU10B, LEU18B, LEU18D, LEU22B, LEU22D, PHE19B, PHE19D, SER15B, SER15D, TRP16B, TRP16D
• B-E: ARG130E, LEU22B, LEU22E, LEU6B, PHE19B, PHE19E, VAL26B
• B-F: ALA23B, ARG17B, ARG17F, ARG20B, ASP14B, ASP14F, ASP8B, ASP8F, GLN9B, GLN9F, GLU13B, GLU13F, HIS11F, HIS12F, ILE21B, ILE7B, LEU10B, LEU10F, LEU18B, LEU22B, LEU6B, LYS4F, PHE19B, PHE19F, SER15B, SER15F, TRP16B, TRP16F
• C-D: ALA132C, ALA132D, ALA181C, ALA181D, ALA188C, ALA188D, ALA23C, ALA23D, ALA46C, ALA46D, ARG119C, ARG119D, ARG124C, ARG124D, ARG130C, ARG130D, ARG162C, ARG162D, ARG178C, ARG178D, ARG17C, ARG17D, ARG184C, ARG184D, ARG20C, ARG20D, ARG47C, ARG47D, ASP146C, ASP146D, ASP14C, ASP14D, ASP169C, ASP169D, ASP185C, ASP185D, ASP193C, ASP193D, ASP8C, ASP8D, GLN156C, GLN156D, GLN186C, GLN186D, GLN195C, GLN195D, GLN9C, GLN9D, GLU101D, GLU13C, GLU13D, GLU147C, GLU147D, GLU150C, GLU150D, GLU158C, GLU158D, GLU174C, GLU174D, GLU192C, GLU192D, GLU24C, GLU24D, GLU27C, GLU27D, GLU30C, GLU30D, GLU34C, GLU34D, GLY140C, GLY140D, GLY141C, GLY141D, GLY143C, GLY143D, GLY171C, GLY171D, GLY175C, GLY175D, GLY190C, GLY190D, GLY28C, GLY28D, HIS11C, HIS11D, HIS12C, HIS12D, HIS161C, HIS161D, HIS52C, HIS52D, ILE100C, ILE100D, ILE21C, ILE21D, ILE7C, ILE7D, LEU102C, LEU102D, LEU10C, LEU10D, LEU118D, LEU127C, LEU127D, LEU138C, LEU138D, LEU145C, LEU145D, LEU148C, LEU148D, LEU152C, LEU152D, LEU154C, LEU154D, LEU155C, LEU155D, LEU167C, LEU167D, LEU176C, LEU176D, LEU180C, LEU180D, LEU183C, LEU183D, LEU18C, LEU18D, LEU194C, LEU194D, LEU196C, LEU196D, LEU22C, LEU22D, LEU32D, LEU6C, LEU6D, LYS125C, LYS125D, LYS159C, LYS159D, LYS187C, LYS187D, LYS3D, LYS4C, LYS4D, PHE121C, PHE121D, PHE122C, PHE122D, PHE128C, PHE128D, PHE142C, PHE142D, PHE163C, PHE163D, PHE182C, PHE182D, PHE197C, PHE197D, PHE19C, PHE19D, PHE25C, PHE25D, PHE29C, PHE29D, PHE43C, PHE43D, PHE48C, PHE48D, PRO139C, PRO139D, PRO191C, PRO191D, PRO53C, PRO5C, PRO5D, SER149C, SER149D, SER15C, SER15D, SER33C, SER33D, SER45C, SER45D, THR144C, THR144D, THR157C, THR157D, THR31C, THR31D, TRP16C, TRP173C, TRP173D, TRP179C, TRP179D, TYR120C, TYR120D, TYR131C, TYR131D, TYR172C, TYR172D, VAL123C, VAL123D, VAL126C, VAL126D, VAL129C, VAL129D, VAL151C, VAL151D, VAL153C, VAL153D, VAL160C, VAL160D, VAL177C, VAL177D, VAL189C, VAL189D, VAL26C, VAL26D
• C-E: ALA23E, ARG119E, ARG17C, ARG17E, ARG20E, ASP14C, ASP14E, GLN9E, GLU13C, GLU13E, HIS11C, HIS12C, LEU18C, LEU18E, LEU22C, LEU22E, PHE19C, PHE19E, SER15C, SER15E, TRP16C, TRP16E
• C-F: ALA23F, LEU22C, LEU22F, PHE19C, PHE19F, TRP16C, TRP16F, VAL26C, VAL26F
• D-E: ALA115D, ALA115E, ALA23D, ALA23E, ARG119D, ARG119E, ARG17D, ARG17E, ARG20D, ARG20E, ASN109E, GLN112D, GLN112E, GLN9D, GLN9E, GLU101D, GLU101E, GLU24D, GLU24E, GLU27D, GLU27E, GLU30D, GLU30E, GLU34D, GLU34E, GLY28D, GLY28E, HIS114D, HIS114E, ILE21D, ILE21E, LEU116D, LEU116E, LEU118D, LEU118E, LEU18D, LEU18E, LEU22D, LEU22E, LEU32D, LEU32E, LEU35D, LEU35E, LEU6D, PHE19D, PHE19E, PHE25D, PHE25E, PHE29D, PHE29E, PRO108D, PRO108E, PRO110D, PRO110E, SER117D, SER117E, SER15D, SER15E, SER33D, SER33E, THR113D, THR113E, THR31D, THR31E, TRP16D, TRP16E, TYR111E, TYR120D, TYR120E, TYR89D, VAL26D, VAL26E
• D-F: ARG119D, ARG17D, ARG20D, ASP14D, ASP14F, GLN9D, GLU13D, GLU13F, HIS11F, HIS12F, LEU18D, LEU18F, LEU22D, LEU22F, PHE19D, PHE19F, SER15D, SER15F, TRP16D, TRP16F
• E-F: ALA132E, ALA132F, ALA181E, ALA181F, ALA188E, ALA188F, ALA23E, ALA23F, ALA46E, ALA46F, ALA54F, ARG119E, ARG119F, ARG124E, ARG124F, ARG130E, ARG130F, ARG162E, ARG162F, ARG178E, ARG178F, ARG17E, ARG17F, ARG184E, ARG184F, ARG20E, ARG20F, ARG47E, ARG47F, ASP146E, ASP146F, ASP14E, ASP14F, ASP169E, ASP169F, ASP185E, ASP185F, ASP193E, ASP193F, ASP8E, ASP8F, GLN156E, GLN156F, GLN186E, GLN186F, GLN195E, GLN195F, GLN9E, GLN9F, GLU101E, GLU13E, GLU13F, GLU147E, GLU147F, GLU150E, GLU150F, GLU158E, GLU158F, GLU174E, GLU174F, GLU192E, GLU192F, GLU24E, GLU24F, GLU27E, GLU27F, GLU30E, GLU30F, GLU34E, GLU34F, GLY140E, GLY140F, GLY141E, GLY141F, GLY143E, GLY143F, GLY171E, GLY171F, GLY175E, GLY175F, GLY190E, GLY190F, GLY28E, GLY28F, GLY44F, HIS11E, HIS11F, HIS12E, HIS12F, HIS161E, HIS161F, HIS52E, HIS52F, ILE100E, ILE100F, ILE21E, ILE21F, ILE7E, ILE7F, LEU10E, LEU10F, LEU118E, LEU127E, LEU127F, LEU138E, LEU145E, LEU145F, LEU148E, LEU148F, LEU152E, LEU152F, LEU154E, LEU154F, LEU155E, LEU155F, LEU167E, LEU167F, LEU176E, LEU176F, LEU180E, LEU180F, LEU183E, LEU183F, LEU18E, LEU18F, LEU194E, LEU194F, LEU196E, LEU196F, LEU199E, LEU22E, LEU22F, LEU32E, LEU32F, LEU6E, LEU6F, LYS125E, LYS125F, LYS159E, LYS159F, LYS187E, LYS187F, LYS4E, LYS4F, PHE121E, PHE121F, PHE122E, PHE122F, PHE128E, PHE128F, PHE142E, PHE142F, PHE163E, PHE163F, PHE182E, PHE182F, PHE197E, PHE197F, PHE19E, PHE19F, PHE25E, PHE25F, PHE29E, PHE29F, PHE43E, PHE43F, PHE48E, PHE48F, PRO139E, PRO139F, PRO191E, PRO191F, PRO53E, PRO53F, PRO5E, PRO5F, SER149E, SER149F, SER15E, SER15F, SER33E, SER33F, SER45E, SER45F, THR144E, THR144F, THR157E, THR157F, THR31E, THR31F, TRP16F, TRP173E, TRP173F, TRP179E, TRP179F, TYR120E, TYR120F, TYR131E, TYR131F, TYR172E, TYR172F, VAL123E, VAL123F, VAL126E, VAL126F, VAL129E, VAL129F, VAL151E, VAL151F, VAL153E, VAL153F, VAL160E, VAL160F, VAL177E, VAL177F, VAL189E, VAL189F, VAL26E, VAL26F