1W9E

crystal structure of the pdz tandem of human syntenin in complex with tnefyf peptide

• Total interactions analyzed: 10
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-T
  • Int. Res.: 43
  • Norm. En. per Res.: -5.347
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-24.912	36.272	-284.728	-273.368	113	14	4	11584	2	28	18
A-R	-52.7599	2.2469	-104.637	-155.15	33	5	3	3432	0	5	3
A-T	-66.2544	-2.126	-161.542	-229.9224	43	8	7	5004	0	4	2
B-S	-65.4834	-2.725	-154.335	-222.5434	44	6	8	4860	0	4	2

Interface residues

• A-B: ALA167A, ALA167B, ALA227A, ALA227B, ALA228A, ALA228B, ALA272A, ALA272B, ARG191A, ARG191B, ARG193A, ARG193B, ARG197A, ARG197B, ARG229A, ARG229B, ASN134A, ASN134B, ASN165A, ASN165B, ASN230A, ASN230B, ASP133A, ASP133B, ASP192A, ASP192B, ASP224A, ASP224B, CYS166A, CYS166B, GLN157A, GLN157B, GLN160A, GLN160B, GLU164A, GLU164B, GLU196A, GLU196B, GLU235A, GLU235B, GLY135A, GLY135B, GLY163A, GLY163B, GLY168A, GLY168B, GLY231A, GLY231B, HIS236A, HIS236B, ILE132A, ILE132B, ILE136A, ILE136B, ILE199A, ILE199B, ILE218A, ILE218B, ILE221A, ILE221B, ILE269A, ILE269B, LEU159A, LEU159B, LEU232A, LEU232B, LEU233A, LEU233B, LYS173B, LYS223A, LYS223B, MET110A, MET110B, MET201A, MET201B, MET270A, MET270B, PHE137A, PHE137B, PHE195A, PHE195B, PHE273A, PHE273B, PRO112A, PRO112B, PRO194A, PRO194B, PRO271A, PRO271B, SER131A, SER131B, SER220A, SER220B, SER225A, SER225B, SER226A, SER226B, THR189A, THR189B, THR198A, THR198B, THR200A, THR200B, THR219A, THR219B, THR234A, THR234B, TRP169A, TRP169B, VAL158A, VAL158B, VAL222A, VAL222B
• A-R: ALA143A, ALA147A, ALA174A, ARG128A, ASP120A, ASP122A, ASP172A, GLN139A, GLN142A, GLN180A, GLU3R, GLY123A, GLY126A, HIS175A, ILE125A, ILE186A, LEU117A, LEU127A, LEU129A, LEU140A, LEU178A, LYS119A, LYS124A, LYS176A, LYS179A, PHE4R, PHE6R, PRO146A, SER145A, SER171A, TYR5R, VAL141A, VAL177A
• A-T: ALA227A, ALA255A, ASN215A, ASN2T, ASP204A, ASP251A, ASP256A, GLN253A, GLU3T, GLY207A, GLY210A, GLY216A, HIS208A, ILE212A, ILE218A, ILE221A, ILE238A, ILE241A, ILE254A, ILE257A, ILE267A, LEU232A, LEU258A, LYS203A, LYS214A, LYS217A, LYS250A, MET201A, PHE211A, PHE213A, PHE4T, PHE6T, SER220A, SER225A, SER252A, SER259A, THR206A, THR219A, TYR5T, VAL209A, VAL222A, VAL246A, VAL265A
• B-S: ALA227B, ALA255B, ASN215B, ASN2S, ASP204B, ASP251B, ASP256B, GLN253B, GLU3S, GLY207B, GLY210B, GLY216B, HIS208B, ILE212B, ILE218B, ILE221B, ILE238B, ILE241B, ILE254B, ILE257B, ILE267B, LEU232B, LEU258B, LYS203B, LYS214B, LYS217B, LYS223B, LYS250B, MET201B, PHE211B, PHE213B, PHE4S, PHE6S, SER220B, SER225B, SER252B, SER259B, THR206B, THR219B, TYR5S, VAL209B, VAL222B, VAL246B, VAL265B