1W2D

human inositol (1,4,5)-trisphosphate 3-kinase complexed with mn2+/adp/ins(1,3,4,5)p4

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 83
  • Norm. En. per Res.: -2.8152
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-65.8262	-2.3706	-165.461	-233.6578	83	22	2	7201	5	48	50

Interface residues

• A-B: ALA294A, ALA294B, ALA338A, ALA338B, ARG308A, ARG319A, ARG319B, ASP253B, ASP256A, ASP256B, ASP287A, ASP296A, ASP296B, ASP339A, ASP339B, ASP345A, ASP345B, ASP405A, ASP405B, CYS259A, CYS259B, CYS342A, CYS342B, CYS407A, CYS407B, GLN364A, GLN364B, GLU333A, GLU333B, GLU361A, GLU361B, GLY257A, GLY257B, GLY334A, GLY334B, GLY340A, GLY340B, HIS305A, HIS406A, HIS406B, HIS408A, ILE322A, ILE322B, ILE335A, ILE335B, LEU293A, LEU293B, LYS286A, LYS290A, LYS290B, LYS291A, LYS291B, LYS336A, LYS336B, LYS337A, LYS337B, LYS347A, LYS347B, MET292A, MET292B, PHE255A, PHE255B, PHE346A, PHE346B, PRO258A, PRO258B, PRO297A, PRO297B, SER341A, SER341B, SER343A, SER343B, THR344A, THR344B, THR348A, THR348B, TRP318A, TYR289A, TYR289B, TYR315A, TYR315B, VAL295A, VAL295B