1W0M

triosephosphate isomerase from thermoproteus tenax

• Total interactions analyzed: 28
• Total true interactions: 12
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 146
  • Norm. En. per Res.: -4.3156
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-138.4474	-14.0489	-477.58	-630.0763	146	29	17	18036	0	44	39
A-C	-29.2592	-5.5499	-252.134	-286.9431	92	5	19	10951	0	23	25
A-D	0.0	0.0	-0.005	-0.005	3	0	0	6	0	0	0
B-C	0.0	0.0	-0.0053	-0.0053	2	0	0	5	0	0	0
B-D	-40.813	-5.6226	-246.638	-293.0736	92	7	19	10883	0	22	25
C-D	-139.2895	1.6363	-465.405	-603.0582	146	32	17	17896	0	45	38
E-F	-141.0913	1.173	-475.15	-615.0683	146	39	17	17927	0	44	38
E-G	-39.7103	-5.25	-250.984	-295.9444	92	9	19	10929	0	23	24
E-H	0.0	0.0	-0.0065	-0.0065	3	0	0	8	0	0	0
F-G	0.0	0.0	-0.0059	-0.0059	2	0	0	5	0	0	0
F-H	-38.9565	-4.7586	-253.802	-297.5171	92	10	19	10982	0	23	25
G-H	-137.9825	2.7118	-458.74	-594.0107	146	31	17	17644	0	45	39

Interface residues

• A-B: ALA12A, ALA12B, ALA16A, ALA16B, ALA17A, ALA17B, ALA202A, ALA202B, ALA21A, ALA21B, ALA42A, ALA42B, ALA61A, ALA61B, ALA64A, ALA64B, ALA68A, ALA68B, ALA71A, ALA71B, ALA74A, ALA74B, ALA84A, ALA84B, ALA96A, ALA96B, ARG20A, ARG20B, ASN44A, ASN44B, ASN80A, ASN80B, ASN92A, ASN92B, ASN9A, ASN9B, ASP65A, ASP65B, CYS120A, CYS120B, GLN53A, GLN53B, GLN62A, GLN62B, GLU141A, GLU141B, GLU15A, GLU15B, GLU47A, GLU47B, GLU79A, GLU79B, GLU83A, GLU83B, GLU95A, GLU95B, GLY147A, GLY147B, GLY14A, GLY14B, GLY18A, GLY18B, GLY49A, GLY49B, GLY63A, GLY63B, GLY69A, GLY69B, GLY70A, GLY70B, GLY85A, GLY85B, GLY86A, GLY86B, HIS45A, HIS45B, HIS72A, HIS72B, HIS75A, HIS75B, HIS93A, HIS93B, ILE146A, ILE146B, ILE81A, ILE81B, ILE90A, ILE90B, LEU200A, LEU200B, LEU46A, LEU46B, LEU48A, LEU48B, LEU50A, LEU50B, LEU78A, LEU78B, LEU91A, LEU91B, LEU98A, LEU98B, LYS11A, LYS11B, LYS19A, LYS19B, LYS207A, LYS207B, LYS82A, LYS82B, PHE10A, PHE10B, PRO43A, PRO43B, PRO97A, PRO97B, SER203A, SER203B, SER52A, SER52B, SER54A, SER54B, SER77A, SER77B, SER94A, SER94B, THR73A, THR73B, TYR13A, TYR13B, TYR60A, TYR60B, VAL206A, VAL206B, VAL22A, VAL22B, VAL51A, VAL51B, VAL59A, VAL59B, VAL66A, VAL66B, VAL76A, VAL76B, VAL89A, VAL89B
• A-C: ALA104A, ALA104C, ALA108A, ALA108C, ALA121A, ALA121C, ALA129A, ALA129C, ALA130A, ALA130C, ALA131A, ALA131C, ALA132A, ALA132C, ALA96A, ALA96C, ARG105A, ARG105C, ARG125A, ARG125C, ARG169A, ARG169C, ASN101A, ASN101C, ASN92A, ASN92C, ASP102A, ASP102C, ASP123A, ASP123C, CYS120A, CYS120C, GLU141A, GLU141C, GLU173A, GLU173C, GLU95A, GLU95C, GLY134A, GLY134C, HIS170A, HIS170C, HIS93A, HIS93C, LEU100A, LEU100C, LEU103A, LEU103C, LEU128A, LEU128C, LEU133A, LEU133C, LEU166A, LEU166C, LEU91A, LEU91C, LEU98A, LEU98C, LYS111A, LYS111C, LYS99A, LYS99C, PHE171A, PHE171C, PRO122A, PRO122C, PRO124A, PRO124C, PRO135A, PRO135C, PRO143A, PRO143C, PRO172A, PRO172C, PRO97A, PRO97C, SER127A, SER127C, SER94A, SER94C, THR126A, THR126C, VAL107A, VAL107C, VAL119A, VAL119C, VAL138A, VAL138C, VAL167A, VAL167C, VAL174A, VAL174C
• A-D: HIS75A, LYS99A, LYS99D
• B-C: LYS99B, LYS99C
• B-D: ALA104B, ALA104D, ALA108B, ALA108D, ALA121B, ALA121D, ALA129B, ALA129D, ALA130B, ALA130D, ALA131B, ALA131D, ALA132B, ALA132D, ALA96B, ALA96D, ARG105B, ARG105D, ARG125B, ARG125D, ARG169B, ARG169D, ASN101B, ASN101D, ASN92B, ASN92D, ASP102B, ASP102D, ASP123B, ASP123D, CYS120B, CYS120D, GLU141B, GLU141D, GLU173B, GLU173D, GLU95B, GLU95D, GLY134B, GLY134D, HIS170B, HIS170D, HIS93B, HIS93D, LEU100B, LEU100D, LEU103B, LEU103D, LEU128B, LEU128D, LEU133B, LEU133D, LEU166B, LEU166D, LEU91B, LEU91D, LEU98B, LEU98D, LYS111B, LYS111D, LYS99B, LYS99D, PHE171B, PHE171D, PRO122B, PRO122D, PRO124B, PRO124D, PRO135B, PRO135D, PRO143B, PRO143D, PRO172B, PRO172D, PRO97B, PRO97D, SER127B, SER127D, SER94B, SER94D, THR126B, THR126D, VAL107B, VAL107D, VAL119B, VAL119D, VAL138B, VAL138D, VAL167B, VAL167D, VAL174B, VAL174D
• C-D: ALA12C, ALA12D, ALA16C, ALA16D, ALA17C, ALA17D, ALA202C, ALA202D, ALA21C, ALA21D, ALA42C, ALA42D, ALA61C, ALA61D, ALA64C, ALA64D, ALA68C, ALA68D, ALA71C, ALA71D, ALA74C, ALA74D, ALA84C, ALA84D, ALA96C, ALA96D, ARG20C, ARG20D, ASN44C, ASN44D, ASN80C, ASN80D, ASN92C, ASN92D, ASN9C, ASN9D, ASP65C, ASP65D, CYS120C, CYS120D, GLN53C, GLN53D, GLN62C, GLN62D, GLU141C, GLU141D, GLU15C, GLU15D, GLU47C, GLU47D, GLU79C, GLU79D, GLU83C, GLU83D, GLU95C, GLU95D, GLY147C, GLY147D, GLY14C, GLY14D, GLY18C, GLY18D, GLY49C, GLY49D, GLY63C, GLY63D, GLY69C, GLY69D, GLY70C, GLY70D, GLY85C, GLY85D, GLY86C, GLY86D, HIS45C, HIS45D, HIS72C, HIS72D, HIS75C, HIS75D, HIS93C, HIS93D, ILE146C, ILE146D, ILE81C, ILE81D, ILE90C, ILE90D, LEU200C, LEU200D, LEU46C, LEU46D, LEU48C, LEU48D, LEU50C, LEU50D, LEU78C, LEU78D, LEU91C, LEU91D, LEU98C, LEU98D, LYS11C, LYS11D, LYS19C, LYS19D, LYS207C, LYS207D, LYS82C, LYS82D, PHE10C, PHE10D, PRO43C, PRO43D, PRO97C, PRO97D, SER203C, SER203D, SER52C, SER52D, SER54C, SER54D, SER77C, SER77D, SER94C, SER94D, THR73C, THR73D, TYR13C, TYR13D, TYR60C, TYR60D, VAL206C, VAL206D, VAL22C, VAL22D, VAL51C, VAL51D, VAL59C, VAL59D, VAL66C, VAL66D, VAL76C, VAL76D, VAL89C, VAL89D
• E-F: ALA12E, ALA12F, ALA16E, ALA16F, ALA17E, ALA17F, ALA202E, ALA202F, ALA21E, ALA21F, ALA42E, ALA42F, ALA61E, ALA61F, ALA64E, ALA64F, ALA68E, ALA68F, ALA71E, ALA71F, ALA74E, ALA74F, ALA84E, ALA84F, ALA96E, ALA96F, ARG20E, ARG20F, ASN44E, ASN44F, ASN80E, ASN80F, ASN92E, ASN92F, ASN9E, ASN9F, ASP65E, ASP65F, CYS120E, CYS120F, GLN53E, GLN53F, GLN62E, GLN62F, GLU141E, GLU141F, GLU15E, GLU15F, GLU47E, GLU47F, GLU79E, GLU79F, GLU83E, GLU83F, GLU95E, GLU95F, GLY147E, GLY147F, GLY14E, GLY14F, GLY18E, GLY18F, GLY49E, GLY49F, GLY63E, GLY63F, GLY69E, GLY69F, GLY70E, GLY70F, GLY85E, GLY85F, GLY86E, GLY86F, HIS45E, HIS45F, HIS72E, HIS72F, HIS75E, HIS75F, HIS93E, HIS93F, ILE146E, ILE146F, ILE81E, ILE81F, ILE90E, ILE90F, LEU200E, LEU200F, LEU46E, LEU46F, LEU48E, LEU48F, LEU50E, LEU50F, LEU78E, LEU78F, LEU91E, LEU91F, LEU98E, LEU98F, LYS11E, LYS11F, LYS19E, LYS19F, LYS207E, LYS207F, LYS82E, LYS82F, PHE10E, PHE10F, PRO43E, PRO43F, PRO97E, PRO97F, SER203E, SER203F, SER52E, SER52F, SER54E, SER54F, SER77E, SER77F, SER94E, SER94F, THR73E, THR73F, TYR13E, TYR13F, TYR60E, TYR60F, VAL206E, VAL206F, VAL22E, VAL22F, VAL51E, VAL51F, VAL59E, VAL59F, VAL66E, VAL66F, VAL76E, VAL76F, VAL89E, VAL89F
• E-G: ALA104E, ALA104G, ALA108E, ALA108G, ALA121E, ALA121G, ALA129E, ALA129G, ALA130E, ALA130G, ALA131E, ALA131G, ALA132E, ALA132G, ALA96E, ALA96G, ARG105E, ARG105G, ARG125E, ARG125G, ARG169E, ARG169G, ASN101E, ASN101G, ASN92E, ASN92G, ASP102E, ASP102G, ASP123E, ASP123G, CYS120E, CYS120G, GLU141E, GLU141G, GLU173E, GLU173G, GLU95E, GLU95G, GLY134E, GLY134G, HIS170E, HIS170G, HIS93E, HIS93G, LEU100E, LEU100G, LEU103E, LEU103G, LEU128E, LEU128G, LEU133E, LEU133G, LEU166E, LEU166G, LEU91E, LEU91G, LEU98E, LEU98G, LYS111E, LYS111G, LYS99E, LYS99G, PHE171E, PHE171G, PRO122E, PRO122G, PRO124E, PRO124G, PRO135E, PRO135G, PRO143E, PRO143G, PRO172E, PRO172G, PRO97E, PRO97G, SER127E, SER127G, SER94E, SER94G, THR126E, THR126G, VAL107E, VAL107G, VAL119E, VAL119G, VAL138E, VAL138G, VAL167E, VAL167G, VAL174E, VAL174G
• E-H: HIS75E, LYS99E, LYS99H
• F-G: LYS99F, LYS99G
• F-H: ALA104F, ALA104H, ALA108F, ALA108H, ALA121F, ALA121H, ALA129F, ALA129H, ALA130F, ALA130H, ALA131F, ALA131H, ALA132F, ALA132H, ALA96F, ALA96H, ARG105F, ARG105H, ARG125F, ARG125H, ARG169F, ARG169H, ASN101F, ASN101H, ASN92F, ASN92H, ASP102F, ASP102H, ASP123F, ASP123H, CYS120F, CYS120H, GLU141F, GLU141H, GLU173F, GLU173H, GLU95F, GLU95H, GLY134F, GLY134H, HIS170F, HIS170H, HIS93F, HIS93H, LEU100F, LEU100H, LEU103F, LEU103H, LEU128F, LEU128H, LEU133F, LEU133H, LEU166F, LEU166H, LEU91F, LEU98F, LEU98H, LYS111F, LYS111H, LYS99F, LYS99H, PHE171F, PHE171H, PRO122F, PRO122H, PRO124F, PRO124H, PRO135F, PRO135H, PRO143F, PRO143H, PRO172F, PRO172H, PRO97F, PRO97H, SER127F, SER127H, SER94F, SER94H, THR126F, THR126H, VAL107F, VAL107H, VAL117H, VAL119F, VAL119H, VAL138F, VAL138H, VAL167F, VAL167H, VAL174F, VAL174H
• G-H: ALA12G, ALA12H, ALA16G, ALA16H, ALA17G, ALA17H, ALA202G, ALA202H, ALA21G, ALA21H, ALA42G, ALA42H, ALA61G, ALA61H, ALA64G, ALA64H, ALA68G, ALA68H, ALA71G, ALA71H, ALA74G, ALA74H, ALA84G, ALA84H, ALA96G, ALA96H, ARG20G, ARG20H, ASN44G, ASN44H, ASN80G, ASN80H, ASN92G, ASN92H, ASN9G, ASN9H, ASP65G, ASP65H, CYS120G, CYS120H, GLN53G, GLN53H, GLN62G, GLN62H, GLU141G, GLU141H, GLU15G, GLU15H, GLU47G, GLU47H, GLU79G, GLU79H, GLU83G, GLU83H, GLU95G, GLU95H, GLY147G, GLY147H, GLY14G, GLY14H, GLY18G, GLY18H, GLY49G, GLY49H, GLY63G, GLY63H, GLY69G, GLY69H, GLY70G, GLY70H, GLY85G, GLY85H, GLY86G, GLY86H, HIS45G, HIS45H, HIS72G, HIS72H, HIS75G, HIS75H, HIS93G, HIS93H, ILE146G, ILE146H, ILE81G, ILE81H, ILE90G, ILE90H, LEU200G, LEU200H, LEU46G, LEU46H, LEU48G, LEU48H, LEU50G, LEU50H, LEU78G, LEU78H, LEU91G, LEU91H, LEU98G, LEU98H, LYS11G, LYS11H, LYS19G, LYS19H, LYS207G, LYS207H, LYS82G, LYS82H, PHE10G, PHE10H, PRO43G, PRO43H, PRO97G, PRO97H, SER203G, SER203H, SER52G, SER52H, SER54G, SER54H, SER77G, SER77H, SER94G, SER94H, THR73G, THR73H, TYR13G, TYR13H, TYR60G, TYR60H, VAL206G, VAL206H, VAL22G, VAL22H, VAL51G, VAL51H, VAL59G, VAL59H, VAL66G, VAL66H, VAL76G, VAL76H, VAL89G, VAL89H