1VYH

paf-ah holoenzyme: lis1/alfa2

• Total interactions analyzed: 190
• Total true interactions: 32
• Strongest Interaction:
  • Chains: H-P
  • Int. Res.: 8
  • Norm. En. per Res.: -7.4579
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-21.677	-87.6185	-278.365	-387.6604	123	22	0	11472	5	62	51
A-C	-33.6018	-18.7652	-97.4325	-149.7995	69	5	0	4301	7	60	61
A-D	0.0	8.034	-28.2017	-20.1677	25	3	0	1259	0	13	14
B-C	0.0	8.7949	-29.8698	-21.0749	27	10	0	1256	0	13	13
B-D	-45.5719	-19.4596	-95.0152	-160.0467	70	10	0	4381	6	59	62
B-G	-6.5262	-11.7509	-64.1689	-82.446	61	4	1	3042	1	16	20
C-F	-3.6681	-6.8049	-73.1364	-83.6094	59	6	1	3094	1	17	19
C-G	0.0	-4.9706	-13.5445	-18.5151	27	0	0	1049	0	14	14
E-F	-19.6205	-98.0986	-292.316	-410.0351	121	19	0	11707	7	61	49
E-G	-21.1678	-25.0411	-101.042	-147.2509	77	5	0	4447	9	58	60
E-H	0.0	9.6539	-25.9125	-16.2586	29	7	0	1188	0	13	14
F-G	0.0	4.3279	-35.7121	-31.3842	29	9	0	1435	0	13	14
F-H	-34.5615	-24.3409	-104.348	-163.2504	72	8	0	4413	9	60	61
F-P	0.0	-2.626	-75.9187	-78.5447	56	5	0	3391	0	16	18
G-K	0.0	0.912	-9.5053	-8.5932	29	0	0	744	0	9	14
H-L	-32.4024	-49.1773	-78.3972	-159.9769	44	10	1	3272	3	17	11
H-P	-10.6556	-41.0582	-7.9497	-59.6636	8	2	0	288	2	8	8
I-J	-31.0571	-94.8157	-288.215	-414.0878	125	20	0	11747	6	62	51
I-K	-34.7458	-17.4779	-95.35	-147.5737	71	5	0	4141	9	62	58
I-L	0.0	5.6969	-39.5448	-33.8479	28	2	0	1355	0	13	14
J-K	0.0	12.4438	-32.6267	-20.1829	28	3	0	1216	1	13	14
J-L	-54.6668	-12.1595	-60.6901	-127.5164	71	6	0	4212	8	57	60
M-N	-29.9063	-83.759	-301.784	-415.4493	121	20	0	11757	3	62	52
M-O	-37.3203	-20.2116	-92.3186	-149.8505	76	7	0	4223	6	59	61
M-P	0.0	11.0238	-26.5561	-15.5323	30	8	0	1246	0	13	14
N-O	0.0	11.2496	-23.081	-11.8314	29	2	0	1160	0	13	12
N-P	-23.1673	-22.2666	-93.2591	-138.693	66	5	0	4108	9	61	60
Q-R	-13.104	-66.624	-285.764	-365.4921	115	16	0	11482	3	62	51
Q-S	-49.8414	-30.4591	-102.929	-183.2295	71	7	0	4533	5	59	60
Q-T	-10.3096	8.3286	-29.5389	-31.5199	30	7	0	1312	0	13	14
R-S	0.0	6.0162	-28.4365	-22.4203	29	2	0	1151	0	13	13
R-T	-40.4559	-29.0074	-83.1369	-152.6002	72	6	0	4264	6	57	62

Interface residues

• A-B: ARG142A, ARG142B, ARG150A, ARG150B, ARG23A, ARG23B, ARG30A, ARG30B, ASN105A, ASN105B, ASN106A, ASN106B, ASN147A, ASN147B, ASN153A, ASN153B, ASN29A, ASN29B, ASN70A, ASP17A, ASP17B, ASP190A, ASP190B, ASP193A, ASP193B, ASP21A, ASP21B, ASP22A, ASP22B, ASP34A, ASP34B, CYS188A, CYS188B, GLN19A, GLN19B, GLN27A, GLN27B, GLN51A, GLN51B, GLN54A, GLN54B, GLN55A, GLN55B, GLU108A, GLU108B, GLU144A, GLU144B, GLU57A, GLU57B, GLY143A, GLY143B, GLY199A, GLY199B, GLY200A, GLY200B, GLY201A, GLY201B, GLY20A, GLY20B, GLY72A, GLY72B, GLY74A, GLY74B, HIS107A, HIS107B, HIS189A, HIS189B, HIS196A, HIS196B, HIS28A, HIS28B, ILE186A, ILE186B, ILE18A, ILE18B, ILE73A, ILE73B, LEU149A, LEU149B, LEU195A, LEU195B, LEU197A, LEU197B, LEU33A, LEU33B, LEU52A, LEU52B, LYS145A, LYS145B, LYS152A, LYS152B, LYS38B, MET191A, MET191B, MET25A, MET25B, PHE192A, PHE192B, PHE194A, PHE194B, PHE31A, PHE31B, PRO141A, PRO146A, PRO146B, PRO148A, PRO148B, SER187A, SER187B, SER26A, SER26B, SER48A, SER48B, THR104A, THR104B, THR198A, THR198B, TRP24A, TRP24B, TYR202A, TYR202B, TYR56A, TYR56B
• A-C: ALA170C, ALA357C, ALA68A, ARG212C, ARG238C, ARG276C, ARG316C, ARG342C, ARG60A, ASN194C, ASN254C, ASN339C, ASN92A, ASP151C, ASP171C, ASP255C, ASP338C, ASP34A, ASP358C, ASP359C, ASP37A, ASP41A, CYS35A, GLN154C, GLN256C, GLN54A, GLU128C, GLU222A, GLU223A, GLU235C, GLU280C, GLU380C, GLU39A, GLU61A, GLU91A, HIS193C, HIS275C, HIS277C, HIS381C, HIS67A, ILE93A, LEU33A, LEU66A, LYS318C, LYS360C, LYS36A, LYS38A, LYS94A, LYS96A, MET172C, MET214A, PHE382C, PHE63A, PRO110C, PRO221A, PRO40A, PRO65A, SER152C, SER169C, SER64A, THR112C, THR150C, THR384C, TRP236C, TRP340C, TRP59A, VAL278C, VAL341C, VAL400C
• A-D: ALA185A, ARG108D, ASP183A, ASP190A, CYS188A, GLN402D, GLU128D, GLY106D, GLY178A, GLY184A, HIS107D, HIS181A, HIS189A, HIS381D, ILE186A, LYS147D, LYS204A, MET191A, PHE179A, PRO110D, SER109D, SER182A, SER187A, VAL180A, VAL400D
• B-C: ALA185B, ARG108C, ASP129C, ASP183B, ASP190B, ASP401C, CYS188B, GLN402C, GLU128C, GLY106C, GLY178B, GLY184B, HIS107C, HIS181B, HIS189B, ILE186B, LYS133C, LYS147C, LYS204B, MET191B, PHE179B, PRO110C, SER109C, SER182B, SER187B, VAL180B, VAL400C
• B-D: ALA170D, ALA357D, ALA68B, ARG212D, ARG238D, ARG276D, ARG316D, ARG342D, ARG60B, ASN194D, ASN254D, ASN339D, ASN92B, ASP151D, ASP171D, ASP255D, ASP317D, ASP338D, ASP34B, ASP358D, ASP359D, ASP37B, ASP401D, ASP41B, CYS35B, GLN154D, GLN256D, GLN54B, GLU128D, GLU222B, GLU223B, GLU235D, GLU280D, GLU380D, GLU39B, GLU57B, GLU61B, HIS193D, HIS275D, HIS277D, HIS379D, HIS381D, HIS67B, ILE93B, LEU33B, LEU66B, LYS318D, LYS360D, LYS36B, LYS38B, LYS96B, MET172D, MET214B, PHE382D, PHE63B, PRO110D, PRO221B, PRO40B, PRO65B, SER152D, SER196D, SER64B, THR150D, TRP236D, TRP340D, TRP59B, VAL278D, VAL341D, VAL400D, VAL42B
• B-G: ALA154B, ALA185B, ARG150B, ARG186G, ASN147B, ASN153B, ASN157B, ASP174B, ASP176B, ASP183B, ASP192G, ASP205G, CYS184G, CYS226G, GLN151B, GLN158B, GLN222G, GLU183G, GLU220G, GLY138B, GLY148G, GLY177B, GLY178B, GLY184B, GLY190G, GLY224G, HIS181B, HIS189G, HIS191G, HIS206G, ILE185G, LEU139B, LEU140B, LEU159B, LEU160B, LEU172B, LEU176G, LYS145B, LYS155B, LYS161B, LYS175G, LYS217G, LYS228G, MET188G, MET218G, PHE179B, PRO141B, PRO146B, SER182B, THR173G, THR175B, THR187G, THR223G, THR229G, TRP177G, TRP219G, TYR225G, VAL156B, VAL162B, VAL180B, VAL227G
• C-F: ALA154F, ALA185F, ARG150F, ARG186C, ASN147F, ASN153F, ASN157F, ASP174F, ASP176F, ASP183F, ASP192C, ASP205C, CYS184C, CYS226C, GLN151F, GLN158F, GLN222C, GLU183C, GLU220C, GLY138F, GLY148C, GLY178F, GLY184F, GLY190C, GLY224C, HIS181F, HIS189C, HIS191C, HIS206C, ILE185C, LEU139F, LEU140F, LEU159F, LEU172F, LEU176C, LYS145F, LYS155F, LYS161F, LYS175C, LYS217C, LYS228C, MET188C, MET218C, PHE182C, PRO141F, PRO146F, SER182F, THR173C, THR175F, THR187C, THR223C, THR229C, TRP177C, TRP219C, TYR225C, VAL156F, VAL162F, VAL180F, VAL227C
• C-G: ARG144C, ARG144G, CYS184C, CYS184G, GLN180G, GLU143C, GLU143G, GLU183C, GLU183G, GLY148C, GLY148G, LEU146C, LYS133C, LYS133G, LYS147C, LYS147G, LYS175C, LYS175G, PHE142C, PHE142G, PHE182C, PHE182G, THR131C, THR145C, THR145G, TRP177C, TRP177G
• E-F: ARG142E, ARG142F, ARG150E, ARG150F, ARG23E, ARG23F, ARG30E, ARG30F, ASN105E, ASN105F, ASN147E, ASN147F, ASN153E, ASN153F, ASN29E, ASN29F, ASP17E, ASP17F, ASP190E, ASP190F, ASP193E, ASP193F, ASP21E, ASP21F, ASP22E, ASP22F, ASP34E, ASP34F, CYS188E, CYS188F, GLN151E, GLN19E, GLN19F, GLN27E, GLN27F, GLN51E, GLN51F, GLN54E, GLN54F, GLN55E, GLN55F, GLU108E, GLU108F, GLU144E, GLU144F, GLU57E, GLU57F, GLY143E, GLY143F, GLY199E, GLY199F, GLY200E, GLY200F, GLY201E, GLY201F, GLY20E, GLY20F, GLY72E, GLY72F, GLY74E, GLY74F, HIS107E, HIS107F, HIS189E, HIS189F, HIS196E, HIS196F, HIS28E, HIS28F, ILE186E, ILE186F, ILE18E, ILE18F, ILE73E, ILE73F, LEU149E, LEU149F, LEU195E, LEU195F, LEU197E, LEU197F, LEU33E, LEU52E, LEU52F, LYS145E, LYS145F, LYS152E, LYS152F, LYS38E, LYS38F, MET191E, MET191F, MET25E, MET25F, PHE192E, PHE192F, PHE194E, PHE194F, PHE31E, PHE31F, PRO141E, PRO146E, PRO146F, PRO148E, PRO148F, SER187E, SER187F, SER26E, SER26F, SER48E, SER48F, THR104E, THR104F, THR198E, THR198F, TRP24E, TRP24F, TYR202E, TYR202F, TYR56E, TYR56F
• E-G: ALA170G, ALA357G, ALA68E, ARG212G, ARG238G, ARG276G, ARG316G, ARG342G, ARG60E, ASN194G, ASN254G, ASN339G, ASN92E, ASP151G, ASP171G, ASP192G, ASP255G, ASP317G, ASP338G, ASP34E, ASP358G, ASP359G, ASP37E, ASP401G, ASP41E, CYS35E, GLN154G, GLN256G, GLN54E, GLU128G, GLU222E, GLU223E, GLU235G, GLU280G, GLU380G, GLU39E, GLU91E, HIS193G, HIS275G, HIS277G, HIS379G, HIS381G, HIS67E, ILE93E, LEU217E, LEU33E, LEU66E, LEU69E, LYS318G, LYS360G, LYS36E, LYS38E, LYS94E, LYS96E, MET172G, MET214E, PHE382G, PHE63E, PRO110G, PRO221E, PRO40E, PRO65E, SER109G, SER152G, SER169G, SER196G, SER64E, THR112G, THR150G, THR220E, TRP236G, TRP340G, TRP59E, VAL278G, VAL341G, VAL400G, VAL42E
• E-H: ALA185E, ARG108H, ASP129H, ASP183E, ASP190E, ASP401H, CYS188E, GLN402H, GLU128H, GLU144E, GLY106H, GLY178E, GLY184E, HIS107H, HIS181E, HIS189E, HIS381H, ILE186E, LYS133H, LYS147H, LYS204E, PHE179E, PHE194E, PRO110H, SER109H, SER182E, SER187E, VAL180E, VAL400H
• F-G: ALA185F, ARG108G, ASP129G, ASP183F, ASP190F, ASP401G, CYS188F, GLN402G, GLU128G, GLY106G, GLY178F, GLY184F, HIS107G, HIS181F, HIS189F, ILE186F, LYS133G, LYS147G, LYS204F, MET191F, PHE142G, PHE179F, PHE194F, PRO110G, SER109G, SER182F, SER187F, VAL180F, VAL400G
• F-H: ALA170H, ALA357H, ALA68F, ARG212H, ARG238H, ARG276H, ARG316H, ARG342H, ARG60F, ASN194H, ASN254H, ASN339H, ASN92F, ASP151H, ASP171H, ASP255H, ASP338H, ASP34F, ASP358H, ASP359H, ASP37F, ASP41F, CYS35F, GLN154H, GLN256H, GLN54F, GLU128H, GLU222F, GLU223F, GLU235H, GLU280H, GLU380H, GLU39F, GLU61F, GLU91F, HIS193H, HIS275H, HIS277H, HIS379H, HIS381H, HIS67F, ILE93F, LEU33F, LEU66F, LYS318H, LYS360H, LYS36F, LYS38F, LYS94F, LYS96F, MET172H, MET214F, PHE382H, PHE63F, PRO110H, PRO221F, PRO40F, PRO65F, SER109H, SER152H, SER169H, SER196H, SER64F, THR150H, TRP236H, TRP340H, TRP59F, VAL195H, VAL278H, VAL341H, VAL400H, VAL42F
• F-P: ALA132F, ALA168F, ALA264P, ARG128F, ASN126F, ASN169F, ASN203P, ASP159P, ASP178P, ASP205P, ASP245P, GLN123F, GLN129F, GLN131F, GLN180P, GLN244P, GLU219F, GLU222F, GLU223F, GLU287P, GLY162P, GLY204P, GLY246P, HIS117P, HIS160P, HIS206P, ILE125F, ILE134F, ILE200P, LEU164F, LEU167F, LEU216F, LYS133F, LYS163P, LYS166F, LYS390P, LYS94F, LYS96F, MET201P, PHE120P, PHE179P, PRO118P, PRO130F, PRO165F, PRO202P, PRO221F, SER161P, SER163F, THR127F, THR220F, THR247P, THR391P, VAL119P, VAL122F, VAL170F, VAL263P
• G-K: ALA296G, ARG276G, ARG371G, ASN369G, GLU287K, GLU295G, GLU93K, GLY298G, GLY308K, GLY349K, ILE293G, ILE293K, LEU334G, LYS321G, LYS351K, LYS368K, LYS370G, LYS92K, MET332G, SER288K, SER289K, SER294G, THR297G, THR319G, THR333G, THR391K, TRP365G, TYR290K, VAL335G
• H-L: ALA296L, ALA392H, ARG371L, ASN369L, ASP136H, ASP141H, ASP178H, ASP366L, GLN180H, GLU138H, GLU143H, GLU295L, GLY140H, GLY162H, GLY298L, HIS117H, HIS389H, ILE293L, LEU164H, LYS163H, LYS351L, LYS368L, LYS370L, MET332L, MET373L, PHE120H, PHE179H, PRO118H, SER121H, SER161H, SER291L, SER292L, SER294L, SER299L, THR139H, THR297L, THR391H, TRP135H, TYR137H, TYR290L, TYR367L, TYR394H, VAL119H, VAL122H
• H-P: ARG234H, ASP136P, GLU138P, LYS214H, SER121P, THR139P, TYR137P, TYR394P
• I-J: ARG142I, ARG142J, ARG150I, ARG150J, ARG23I, ARG23J, ARG30I, ARG30J, ARG60J, ASN105I, ASN105J, ASN106I, ASN106J, ASN147I, ASN147J, ASN153I, ASN153J, ASN29I, ASN29J, ASN70I, ASN70J, ASP17I, ASP17J, ASP190I, ASP190J, ASP193I, ASP193J, ASP21I, ASP21J, ASP22I, ASP22J, ASP34J, CYS188I, CYS188J, GLN151J, GLN19I, GLN19J, GLN27I, GLN27J, GLN51I, GLN51J, GLN54I, GLN54J, GLN55I, GLN55J, GLU108I, GLU108J, GLU144I, GLU144J, GLU57I, GLU57J, GLY143I, GLY143J, GLY199I, GLY199J, GLY200I, GLY200J, GLY201I, GLY201J, GLY20I, GLY20J, GLY72I, GLY72J, GLY74I, GLY74J, HIS107I, HIS107J, HIS189I, HIS189J, HIS196I, HIS196J, HIS28I, HIS28J, ILE186I, ILE186J, ILE18I, ILE18J, ILE73I, ILE73J, LEU149I, LEU149J, LEU195I, LEU195J, LEU197I, LEU197J, LEU52I, LEU52J, LYS145I, LYS145J, LYS152I, LYS152J, LYS38I, LYS38J, MET191I, MET191J, MET25I, MET25J, PHE192I, PHE192J, PHE194I, PHE194J, PHE31I, PHE31J, PRO141I, PRO141J, PRO146I, PRO146J, PRO148I, PRO148J, SER187I, SER187J, SER26I, SER26J, SER48I, SER48J, THR104I, THR104J, THR198I, THR198J, TRP24I, TRP24J, TYR202I, TYR202J, TYR56I, TYR56J
• I-K: ALA170K, ALA68I, ARG212K, ARG238K, ARG276K, ARG316K, ARG342K, ARG60I, ASN194K, ASN254K, ASN339K, ASN92I, ASP151K, ASP171K, ASP255K, ASP338K, ASP34I, ASP358K, ASP359K, ASP37I, ASP401K, ASP41I, CYS35I, GLN154K, GLN256K, GLN54I, GLU128K, GLU222I, GLU223I, GLU235K, GLU280K, GLU380K, GLU39I, GLU91I, HIS193K, HIS275K, HIS277K, HIS379K, HIS381K, HIS67I, ILE93I, LEU33I, LEU66I, LYS318K, LYS360K, LYS36I, LYS38I, LYS94I, LYS96I, MET172K, MET214I, PHE382K, PHE63I, PRO110K, PRO221I, PRO40I, PRO65I, SER109K, SER152K, SER169K, SER64I, THR112K, THR150K, THR220I, TRP236K, TRP340K, TRP59I, VAL278K, VAL341K, VAL400K, VAL42I
• I-L: ALA185I, ARG108L, ASP129L, ASP183I, ASP190I, CYS188I, GLN402L, GLU128L, GLU144I, GLY106L, GLY178I, GLY184I, HIS107L, HIS181I, HIS189I, ILE186I, LYS133L, LYS147L, LYS204I, MET191I, PHE179I, PHE194I, PRO110L, SER109L, SER182I, SER187I, VAL180I, VAL400L
• J-K: ALA185J, ARG108K, ARG150J, ASP129K, ASP183J, ASP190J, CYS188J, GLN402K, GLU128K, GLU144J, GLY106K, GLY178J, GLY184J, HIS107K, HIS181J, HIS189J, ILE186J, LYS133K, LYS147K, LYS204J, PHE179J, PHE194J, PRO110K, SER109K, SER182J, SER187J, VAL180J, VAL400K
• J-L: ALA170L, ALA357L, ALA68J, ARG212L, ARG238L, ARG276L, ARG316L, ARG342L, ARG60J, ASN194L, ASN254L, ASN339L, ASN92J, ASP151L, ASP171L, ASP255L, ASP338L, ASP34J, ASP358L, ASP359L, ASP37J, ASP41J, CYS35J, GLN154L, GLN256L, GLN54J, GLU128L, GLU222J, GLU223J, GLU235L, GLU280L, GLU380L, GLU39J, GLU61J, GLU91J, HIS193L, HIS275L, HIS277L, HIS379L, HIS381L, HIS67J, ILE93J, LEU33J, LEU66J, LYS318L, LYS360L, LYS36J, LYS38J, LYS94J, LYS96J, MET172L, MET214J, PHE382L, PHE63J, PRO110L, PRO221J, PRO40J, PRO65J, SER109L, SER152L, SER169L, SER64J, THR112L, THR150L, THR220J, TRP236L, TRP340L, TRP59J, VAL195L, VAL278L, VAL400L
• M-N: ARG142M, ARG142N, ARG150M, ARG150N, ARG23M, ARG23N, ARG30M, ARG30N, ASN105M, ASN105N, ASN106M, ASN147M, ASN147N, ASN153N, ASN29M, ASN29N, ASP17M, ASP17N, ASP190M, ASP190N, ASP193M, ASP193N, ASP21M, ASP21N, ASP22M, ASP22N, ASP34M, CYS188M, CYS188N, GLN19M, GLN19N, GLN27M, GLN27N, GLN51M, GLN51N, GLN54M, GLN54N, GLN55M, GLN55N, GLU108M, GLU108N, GLU144M, GLU144N, GLU57M, GLU57N, GLY143M, GLY143N, GLY199M, GLY199N, GLY200M, GLY200N, GLY201M, GLY201N, GLY20M, GLY20N, GLY72M, GLY72N, GLY74M, GLY74N, HIS107M, HIS107N, HIS189M, HIS189N, HIS196M, HIS196N, HIS28M, HIS28N, ILE186M, ILE186N, ILE18M, ILE18N, ILE73M, ILE73N, LEU149M, LEU149N, LEU195M, LEU195N, LEU197M, LEU197N, LEU33M, LEU33N, LEU52M, LEU52N, LYS145M, LYS145N, LYS152M, LYS152N, LYS38M, LYS38N, MET191M, MET191N, MET25M, MET25N, PHE192M, PHE192N, PHE194M, PHE194N, PHE31M, PHE31N, PRO141M, PRO141N, PRO146M, PRO146N, PRO148M, PRO148N, SER187M, SER187N, SER26M, SER26N, SER48M, SER48N, THR104M, THR104N, THR198M, THR198N, TRP24M, TRP24N, TYR202M, TYR202N, TYR56M, TYR56N
• M-O: ALA170O, ALA357O, ALA68M, ARG212O, ARG238O, ARG276O, ARG316O, ARG342O, ARG60M, ASN194O, ASN254O, ASN339O, ASN92M, ASP151O, ASP171O, ASP255O, ASP317O, ASP338O, ASP34M, ASP358O, ASP359O, ASP37M, ASP41M, CYS35M, GLN154O, GLN256O, GLN54M, GLU128O, GLU218M, GLU222M, GLU223M, GLU235O, GLU280O, GLU380O, GLU39M, GLU57M, GLU61M, GLU91M, HIS193O, HIS275O, HIS277O, HIS381O, HIS67M, ILE93M, LEU33M, LEU66M, LYS318O, LYS360O, LYS36M, LYS38M, LYS94M, LYS96M, MET172O, MET214M, PHE382O, PHE63M, PRO110O, PRO221M, PRO40M, PRO65M, SER109O, SER152O, SER169O, SER196O, SER64M, THR150O, THR220M, THR384O, TRP236O, TRP340O, TRP59M, VAL195O, VAL278O, VAL341O, VAL400O, VAL42M
• M-P: ALA185M, ARG108P, ASP129P, ASP183M, ASP190M, ASP401P, CYS188M, GLN402P, GLU128P, GLU144M, GLY106P, GLY178M, GLY184M, HIS107P, HIS181M, HIS189M, HIS381P, ILE186M, LYS133P, LYS147P, LYS204M, MET191M, PHE179M, PRO110P, SER105P, SER109P, SER182M, SER187M, VAL180M, VAL400P
• N-O: ALA185N, ARG108O, ARG150N, ASP183N, ASP190N, ASP401O, CYS188N, GLN402O, GLU128O, GLU144N, GLY106O, GLY178N, GLY184N, HIS107O, HIS181N, HIS189N, HIS381O, ILE186N, LYS133O, LYS147O, LYS204N, PHE179N, PHE194N, PRO110O, SER109O, SER182N, SER187N, VAL180N, VAL400O
• N-P: ALA170P, ALA357P, ALA68N, ARG212P, ARG238P, ARG276P, ARG316P, ARG342P, ARG60N, ASN194P, ASN254P, ASN339P, ASN92N, ASP151P, ASP171P, ASP255P, ASP338P, ASP34N, ASP358P, ASP359P, ASP37N, ASP41N, CYS35N, GLN154P, GLN256P, GLU128P, GLU222N, GLU223N, GLU235P, GLU280P, GLU380P, GLU39N, GLU61N, HIS193P, HIS275P, HIS277P, HIS381P, HIS67N, ILE93N, LEU33N, LEU66N, LEU69N, LYS318P, LYS360P, LYS36N, LYS38N, LYS96N, MET172P, MET214N, PHE382P, PHE63N, PRO110P, PRO221N, PRO40N, PRO65N, SER109P, SER152P, SER196P, SER64N, THR150P, TRP236P, TRP340P, TRP59N, VAL278P, VAL341P, VAL400P
• Q-R: ARG142Q, ARG142R, ARG150Q, ARG150R, ARG23Q, ARG23R, ARG30Q, ARG30R, ASN105Q, ASN105R, ASN147Q, ASN147R, ASN29Q, ASN29R, ASP17Q, ASP17R, ASP190Q, ASP190R, ASP193Q, ASP193R, ASP21Q, ASP21R, ASP22Q, ASP22R, ASP34Q, ASP34R, CYS188Q, CYS188R, GLN19Q, GLN19R, GLN27Q, GLN27R, GLN51Q, GLN51R, GLN54Q, GLN54R, GLN55Q, GLN55R, GLU108Q, GLU108R, GLU144Q, GLU144R, GLU57Q, GLU57R, GLY143Q, GLY143R, GLY199Q, GLY199R, GLY200Q, GLY200R, GLY201Q, GLY201R, GLY20Q, GLY20R, GLY72Q, GLY72R, GLY74Q, GLY74R, HIS107Q, HIS107R, HIS189Q, HIS189R, HIS196Q, HIS196R, HIS28Q, HIS28R, ILE186R, ILE18Q, ILE18R, ILE73Q, ILE73R, LEU149Q, LEU149R, LEU195Q, LEU195R, LEU197Q, LEU197R, LEU33Q, LEU33R, LEU52Q, LEU52R, LYS145Q, LYS145R, LYS152Q, LYS152R, MET191Q, MET191R, MET25Q, MET25R, PHE192Q, PHE192R, PHE194Q, PHE194R, PHE31Q, PHE31R, PRO146Q, PRO146R, PRO148Q, PRO148R, SER187Q, SER187R, SER26Q, SER26R, SER48Q, SER48R, THR104Q, THR104R, THR198Q, THR198R, TRP24Q, TRP24R, TYR202Q, TYR202R, TYR56Q, TYR56R
• Q-S: ALA170S, ALA357S, ALA68Q, ARG212S, ARG238S, ARG273S, ARG276S, ARG316S, ARG342S, ARG60Q, ASN194S, ASN254S, ASN339S, ASN92Q, ASP151S, ASP171S, ASP255S, ASP338S, ASP34Q, ASP358S, ASP359S, ASP37Q, ASP401S, ASP41Q, CYS35Q, GLN154S, GLN256S, GLU128S, GLU222Q, GLU223Q, GLU235S, GLU280S, GLU380S, GLU39Q, GLU91Q, HIS193S, HIS275S, HIS277S, HIS379S, HIS381S, HIS67Q, ILE93Q, LEU33Q, LEU66Q, LYS318S, LYS360S, LYS36Q, LYS38Q, LYS94Q, LYS96Q, MET172S, MET214Q, PHE382S, PHE63Q, PRO110S, PRO221Q, PRO40Q, PRO65Q, SER152S, SER196S, SER64Q, THR112S, THR150S, THR220Q, TRP236S, TRP340S, TRP59Q, VAL278S, VAL341S, VAL400S, VAL42Q
• Q-T: ALA185Q, ARG108T, ARG150Q, ASP129T, ASP183Q, ASP190Q, ASP401T, CYS188Q, GLN402T, GLU128T, GLU144Q, GLY106T, GLY178Q, GLY184Q, HIS107T, HIS181Q, HIS189Q, ILE186Q, LYS133T, LYS147T, LYS204Q, MET191Q, PHE179Q, PHE194Q, PRO110T, SER109T, SER182Q, SER187Q, VAL180Q, VAL400T
• R-S: ALA185R, ARG108S, ARG150R, ASP129S, ASP183R, ASP190R, ASP401S, CYS188R, GLN402S, GLU128S, GLU144R, GLY106S, GLY178R, GLY184R, HIS107S, HIS181R, HIS189R, ILE186R, LYS133S, LYS147S, LYS204R, PHE179R, PHE194R, PRO110S, SER109S, SER182R, SER187R, VAL180R, VAL400S
• R-T: ALA170T, ALA357T, ALA68R, ARG212T, ARG238T, ARG276T, ARG316T, ARG342T, ARG60R, ASN194T, ASN254T, ASN339T, ASN92R, ASP151T, ASP171T, ASP255T, ASP317T, ASP338T, ASP34R, ASP358T, ASP359T, ASP37R, ASP401T, ASP41R, CYS35R, GLN154T, GLN256T, GLN54R, GLU128T, GLU222R, GLU223R, GLU235T, GLU280T, GLU380T, GLU39R, GLU91R, HIS193T, HIS275T, HIS277T, HIS379T, HIS381T, HIS67R, ILE93R, LEU33R, LEU66R, LYS318T, LYS360T, LYS36R, LYS38R, LYS94R, LYS96R, MET172T, MET214R, PHE382T, PHE63R, PRO110T, PRO221R, PRO40R, PRO65R, SER109T, SER152T, SER64R, THR150T, THR220R, THR384T, TRP236T, TRP340T, TRP59R, VAL278T, VAL341T, VAL400T, VAL42R