1VU1

structure-function analysis of receptor-binding in adeno-associated virus serotype 6 (aav-6)

• Total interactions analyzed: 190
• Total true interactions: 39
• Strongest Interaction:
  • Chains: o-t
  • Int. Res.: 135
  • Norm. En. per Res.: -5.966
• Hub Node: O(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
o-p	-77.2113	-2.2454	-661.153	-740.6097	214	44	13	26347	1	19	18
o-q	0.0	0.0	-0.0275	-0.0275	5	0	0	15	0	0	1
o-r	0.0	0.0	-0.0276	-0.0276	5	0	0	15	0	0	1
o-s	-80.4299	-3.1083	-662.966	-746.5043	213	44	13	26445	1	19	18
o-t	-176.9014	-238.7201	-389.789	-805.4105	135	32	2	15533	16	32	35
o-w	0.0	0.0	-7.428	-7.428	12	0	2	511	0	0	1
o-x	-311.924	-22.3552	-1547.09	-1881.3692	342	135	27	59105	7	61	66
p-q	-77.4229	-2.9487	-667.21	-747.5816	213	47	13	26355	1	19	17
p-r	0.0	0.0	-0.0251	-0.0251	5	0	0	14	0	0	1
p-s	0.0	0.0	-0.0264	-0.0264	5	0	0	15	0	0	1
q-r	-77.607	-2.7289	-679.723	-760.0589	228	43	13	26414	1	19	18
q-s	0.0	0.0	-0.031	-0.031	5	0	0	16	0	0	1
r-s	-101.8074	-2.8887	-679.461	-784.1571	228	50	13	26754	1	19	18
r-t	0.0	0.0	-8.1705	-8.1705	12	0	2	519	0	0	1
s-t	-306.3886	-23.43	-1549.62	-1879.4386	341	131	26	58964	7	61	66
t-u	-84.334	-4.1106	-687.773	-776.2176	214	51	13	26914	1	19	18
t-v	0.0	0.0	-0.0326	-0.0326	5	0	0	18	0	0	1
t-w	0.0	0.0	-0.0271	-0.0271	5	0	0	16	0	0	1
t-x	-88.0137	-4.1686	-661.21	-753.3923	215	54	14	26611	1	19	17
u-v	-98.1528	-4.6416	-693.906	-796.7004	215	47	13	26907	1	19	18
u-w	0.0	0.0	-0.0296	-0.0296	5	0	0	16	0	0	1
u-x	0.0	0.0	-0.0265	-0.0265	5	0	0	16	0	0	1
v-w	-92.8846	-4.8081	-677.514	-775.2067	215	46	14	26608	1	19	18
v-x	0.0	0.0	-0.0265	-0.0265	5	0	0	15	0	0	1
w-x	-87.0577	-3.144	-654.844	-745.0457	213	47	13	26320	1	19	17
y-z	-83.5847	-2.1047	-675.467	-761.1564	213	48	13	26612	1	19	17
y-0	0.0	0.0	-0.0261	-0.0261	5	0	0	15	0	0	1
y-2	-82.7269	-4.643			24
y-3	-176.069	-237.1618			30
y-7	-325.3766	-27.0407			83
z-0	-76.7887	-4.1431	-454.785	-535.7167	168	33	9	18016	1	14	13
0-1	-73.3684	-3.0915			23
1-2	-73.8497	-2.7899			21
2-3	-306.3277	-23.4596			80
3-4	-83.8523	-4.9136			25
3-7	-79.0819	-2.8009			25
4-5	-83.87	-3.4186			25
5-6	-76.0337	-3.638			23
6-7	-77.0497	-3.7462			22

Interface residues

• o-p: ALA218o, ALA224p, ALA248p, ALA263o, ALA334o, ALA334p, ALA368p, ALA387o, ALA548p, ALA656o, ALA660o, ALA664o, ALA668o, ALA706p, ALA709p, ARG245p, ARG287p, ARG295p, ARG299p, ARG390o, ARG405o, ARG405p, ASN223o, ASN223p, ASN227p, ASN253o, ASN253p, ASN254p, ASN318p, ASN327o, ASN335o, ASN335p, ASN336o, ASN336p, ASN382o, ASN383o, ASN408o, ASN408p, ASN409o, ASN409p, ASN651p, ASN657o, ASN704p, ASN710p, ASN717p, ASN718p, ASP219o, ASP219p, ASP231p, ASP296p, ASP328o, ASP369p, ASP712p, ASP716p, CYS230p, CYS290p, CYS362p, CYS395o, GLN259o, GLN320p, GLN342o, GLN350o, GLN360p, GLN375p, GLN386o, GLN402o, GLN673o, GLN673p, GLN678p, GLU323o, GLU323p, GLU348o, GLU397o, GLU546p, GLU661o, GLY217o, GLY220o, GLY220p, GLY222o, GLY222p, GLY226p, GLY275o, GLY281p, GLY329p, GLY361p, GLY384o, GLY389o, GLY407o, GLY407p, GLY677p, GLY719p, HIS229p, HIS255o, HIS291p, HIS359p, ILE240p, ILE260o, ILE319o, ILE319p, ILE333p, ILE373p, ILE671o, LEU249p, LEU256o, LEU337o, LEU337p, LEU381o, LEU396o, LEU404o, LEU720p, LYS258o, LYS258p, LYS322p, LYS650o, LYS666o, LYS707p, MET372p, MET403o, PHE274o, PHE292p, PHE317p, PHE344o, PHE366p, PHE371p, PHE393o, PHE399o, PHE410o, PHE662o, PHE667o, PHE670o, PHE713p, PRO250p, PRO279o, PRO294p, PRO364p, PRO367p, PRO374p, PRO400o, PRO653o, PRO655o, PRO658o, PRO659o, SER225p, SER232p, SER243p, SER261o, SER277o, SER293p, SER339o, SER385o, SER391o, SER392o, SER401o, SER663o, SER669o, SER675p, SER703p, SER708p, THR233p, THR241p, THR242p, THR244p, THR246p, THR251p, THR278o, THR325o, THR325p, THR326o, THR326p, THR331p, THR332o, THR332p, THR338o, THR340o, THR380o, THR406o, THR406p, THR652o, THR665o, THR672o, THR672p, THR676p, THR702p, THR714p, THR722p, TRP228p, TRP234p, TRP247p, TRP280o, TRP297p, TYR252p, TYR257o, TYR276o, TYR282p, TYR376p, TYR378o, TYR394o, TYR398o, TYR674p, TYR705p, TYR721p, VAL221o, VAL221p, VAL321o, VAL321p, VAL324p, VAL330p, VAL341o, VAL343o, VAL370p, VAL388o, VAL654o, VAL711p, VAL715p
• o-q: ARG405o, GLY222q, LEU337o, LEU337q, THR338o
• o-r: ARG405r, GLY222o, LEU337o, LEU337r, THR338r
• o-s: ALA218s, ALA224o, ALA248o, ALA263s, ALA334o, ALA334s, ALA368o, ALA387s, ALA548o, ALA656s, ALA660s, ALA664s, ALA668s, ALA706o, ALA709o, ARG245o, ARG287o, ARG295o, ARG299o, ARG390s, ARG405o, ARG405s, ASN223o, ASN223s, ASN227o, ASN253o, ASN253s, ASN254o, ASN318o, ASN327s, ASN335o, ASN335s, ASN336o, ASN336s, ASN382s, ASN383s, ASN408o, ASN408s, ASN409o, ASN409s, ASN651o, ASN657s, ASN704o, ASN710o, ASN717o, ASN718o, ASP219o, ASP219s, ASP231o, ASP296o, ASP328s, ASP369o, ASP712o, ASP716o, CYS230o, CYS290o, CYS362o, CYS395s, GLN259s, GLN320o, GLN342s, GLN350s, GLN360o, GLN375o, GLN386s, GLN402s, GLN673o, GLN673s, GLN678o, GLU323o, GLU323s, GLU348s, GLU397s, GLU546o, GLU661s, GLY217s, GLY220o, GLY220s, GLY222o, GLY222s, GLY226o, GLY275s, GLY281o, GLY329o, GLY361o, GLY384s, GLY389s, GLY407o, GLY407s, GLY677o, GLY719o, HIS229o, HIS255s, HIS291o, HIS359o, ILE240o, ILE260s, ILE319o, ILE319s, ILE333o, ILE373o, ILE671s, LEU249o, LEU256s, LEU337o, LEU337s, LEU381s, LEU396s, LEU404s, LEU720o, LYS258o, LYS258s, LYS322o, LYS650s, LYS666s, LYS707o, MET372o, MET403s, PHE274s, PHE292o, PHE317o, PHE344s, PHE366o, PHE371o, PHE393s, PHE399s, PHE410s, PHE662s, PHE667s, PHE670s, PHE713o, PRO250o, PRO279s, PRO294o, PRO364o, PRO367o, PRO374o, PRO400s, PRO653s, PRO655s, PRO658s, PRO659s, SER225o, SER232o, SER243o, SER261s, SER277s, SER293o, SER339s, SER385s, SER391s, SER392s, SER401s, SER663s, SER669s, SER675o, SER703o, SER708o, THR233o, THR241o, THR242o, THR244o, THR246o, THR251o, THR278s, THR325o, THR325s, THR326o, THR326s, THR331o, THR332o, THR338s, THR340s, THR380s, THR406o, THR406s, THR652s, THR665s, THR672o, THR672s, THR676o, THR702o, THR714o, THR722o, TRP228o, TRP234o, TRP247o, TRP280s, TRP297o, TYR252o, TYR257s, TYR276s, TYR282o, TYR376o, TYR378s, TYR394s, TYR398s, TYR674o, TYR705o, TYR721o, VAL221o, VAL221s, VAL321o, VAL321s, VAL324o, VAL330o, VAL341s, VAL343s, VAL370o, VAL388s, VAL654s, VAL711o, VAL715o
• o-t: ALA368o, ALA368t, ALA706o, ALA706t, ARG245o, ARG245t, ARG295o, ARG295t, ARG299o, ARG299t, ARG694o, ARG694t, ARG725o, ARG725t, ASN302o, ASN302t, ASN303o, ASN303t, ASN304o, ASN304t, ASN691o, ASN691t, ASN696o, ASN696t, ASN704o, ASN704t, ASP231o, ASP231t, ASP296o, ASP296t, ASP529o, ASP529t, ASP530o, ASP530t, ASP532o, ASP532t, ASP712o, ASP712t, CYS230o, CYS230t, CYS290o, CYS290t, GLN298o, GLN298t, GLN700o, GLN700t, GLU564o, GLU564t, GLU565o, GLU565t, GLU690o, GLU690t, GLU698o, GLU698t, GLU723o, GLU723t, GLY236o, GLY236t, HIS289o, HIS289t, HIS291o, HIS291t, ILE301o, ILE727o, ILE727t, LEU614o, LEU614t, LEU732o, LEU732t, LYS567o, LYS567t, LYS689o, LYS689t, LYS693o, LYS693t, LYS707o, LYS707t, PHE292o, PHE292t, PHE366o, PHE366t, PHE713o, PHE713t, PRO294o, PRO294t, PRO364o, PRO364t, PRO365o, PRO365t, PRO367o, PRO367t, PRO697o, PRO697t, PRO724o, PRO724t, SER232o, SER232t, SER243o, SER243t, SER293o, SER293t, SER692o, SER692t, SER703o, SER703t, THR233o, THR233t, THR702o, THR702t, THR714o, THR714t, THR733o, THR733t, TRP234o, TRP234t, TRP297o, TRP297t, TRP305o, TRP305t, TRP695o, TRP695t, TYR701o, TYR701t, TYR705o, TYR705t, TYR721o, TYR721t, TYR731o, TYR731t, VAL699o, VAL699t, VAL711o, VAL711t, VAL715o, VAL715t
• o-w: ALA664w, ARG465o, ASN436o, ASP440o, GLN441o, GLU661w, ILE439o, LEU438o, PHE662w, SER663w, THR665w, TYR442o
• o-x: ALA267x, ALA358x, ALA426o, ALA456o, ALA469o, ALA506x, ALA523x, ALA525o, ALA548x, ALA550x, ALA554x, ALA568o, ALA573x, ALA581o, ALA592o, ALA601o, ALA601x, ALA620x, ARG287x, ARG390x, ARG433o, ARG448o, ARG465o, ARG485o, ARG485x, ARG488x, ARG514x, ARG576o, ARG576x, ARG610o, ARG610x, ARG694o, ARG730o, ARG734o, ASN253x, ASN269x, ASN271x, ASN286x, ASN302o, ASN382x, ASN383x, ASN436o, ASN447o, ASN451o, ASN458o, ASN477o, ASN496x, ASN497x, ASN498x, ASN500x, ASN510o, ASN510x, ASN512x, ASN519x, ASN552x, ASN557x, ASN570o, ASN570x, ASN583o, ASN691o, ASN696o, ASP270x, ASP284x, ASP346x, ASP432o, ASP440o, ASP460o, ASP495x, ASP529o, ASP530o, ASP556x, ASP590o, ASP595o, ASP595x, ASP609o, ASP609x, ASP611o, ASP626x, CYS362x, CYS395x, CYS483o, CYS483x, GLN350x, GLN360x, GLN375x, GLN386x, GLN429o, GLN441o, GLN450o, GLN452o, GLN457o, GLN474o, GLN486x, GLN487x, GLN585o, GLN608o, GLN608x, GLN615x, GLN646x, GLN688o, GLN700o, GLU348x, GLU397x, GLU515x, GLU546x, GLU564o, GLU565o, GLU575o, GLU575x, GLU698o, GLY266x, GLY275x, GLY281x, GLY306o, GLY356x, GLY361x, GLY377x, GLY384x, GLY389x, GLY466o, GLY470o, GLY481o, GLY481x, GLY505x, GLY513x, GLY521x, GLY539x, GLY544x, GLY549x, GLY578o, GLY594o, GLY600o, GLY600x, GLY604o, GLY616x, GLY627o, GLY627x, GLY636x, GLY637o, GLY637x, GLY639x, HIS272x, HIS289x, HIS359x, HIS422o, HIS427o, HIS527o, HIS597o, HIS597x, HIS624x, HIS628o, HIS628x, HIS630o, HIS630x, ILE260x, ILE373x, ILE439o, ILE517x, ILE518x, ILE542x, ILE560x, ILE566o, ILE618x, ILE622x, LEU351x, LEU355x, LEU379x, LEU381x, LEU396x, LEU431o, LEU434o, LEU438o, LEU443o, LEU446o, LEU461o, LEU462o, LEU479o, LEU511x, LEU555x, LEU584o, LEU584x, LEU602o, LEU602x, LEU634x, LEU640x, LEU732o, LEU736o, LYS258x, LYS459o, LYS476o, LYS491x, LYS493x, LYS508x, LYS528o, LYS528x, LYS531o, LYS531x, LYS533x, LYS545x, LYS567o, LYS621x, LYS693o, MET435o, MET471o, MET524x, MET537x, MET541x, MET559x, MET599o, MET599x, MET605o, MET605x, MET635x, PHE274x, PHE288x, PHE344x, PHE393x, PHE399x, PHE421o, PHE463o, PHE501x, PHE534x, PHE535x, PHE543x, PHE577o, PHE629o, PHE629x, PHE638x, PRO279x, PRO352x, PRO374x, PRO400x, PRO420o, PRO437o, PRO468o, PRO475o, PRO480o, PRO482o, PRO482x, PRO520x, PRO536x, PRO571o, PRO591o, PRO603o, PRO603x, PRO617x, PRO623x, PRO631x, PRO633x, PRO697o, PRO735o, SER261x, SER262x, SER268x, SER277x, SER357x, SER385x, SER391x, SER392x, SER423o, SER424o, SER428o, SER430o, SER464o, SER467o, SER472o, SER490x, SER499x, SER507x, SER516x, SER538x, SER547x, SER551x, SER586o, SER587o, SER588o, SER632o, SER632x, SER692o, THR265x, THR278x, THR380x, THR449o, THR492x, THR494x, THR502x, THR504x, THR522x, THR553x, THR561x, THR569o, THR574o, THR574x, THR579o, THR589o, THR593o, THR625x, THR729o, THR733o, TRP280x, TRP305o, TRP478o, TRP503x, TRP607o, TRP607x, TRP619x, TRP695o, TYR252x, TYR273x, TYR276x, TYR282x, TYR349x, TYR353x, TYR376x, TYR378x, TYR394x, TYR398x, TYR425o, TYR442o, TYR444o, TYR445o, TYR484x, TYR509x, TYR613x, TYR701o, TYR731o, VAL354x, VAL388x, VAL473o, VAL489x, VAL540x, VAL558x, VAL572o, VAL572x, VAL580o, VAL582o, VAL596o, VAL596x, VAL598o, VAL598x, VAL606o, VAL699o
• p-q: ALA218p, ALA224q, ALA248q, ALA263p, ALA334p, ALA334q, ALA368q, ALA387p, ALA548q, ALA656p, ALA660p, ALA664p, ALA668p, ALA706q, ALA709q, ARG245q, ARG287q, ARG295q, ARG299q, ARG390p, ARG405p, ARG405q, ASN223p, ASN223q, ASN227q, ASN253p, ASN253q, ASN254q, ASN318q, ASN327p, ASN335p, ASN335q, ASN336p, ASN336q, ASN382p, ASN383p, ASN408p, ASN408q, ASN409p, ASN409q, ASN651q, ASN657p, ASN704q, ASN710q, ASN717q, ASN718q, ASP219p, ASP219q, ASP231q, ASP296q, ASP328p, ASP369q, ASP712q, ASP716q, CYS230q, CYS290q, CYS362q, CYS395p, GLN259p, GLN320q, GLN342p, GLN350p, GLN360q, GLN375q, GLN386p, GLN402p, GLN673p, GLN673q, GLN678q, GLU323p, GLU323q, GLU348p, GLU397p, GLU546q, GLU661p, GLY217p, GLY220p, GLY220q, GLY222p, GLY222q, GLY226q, GLY275p, GLY281q, GLY329q, GLY361q, GLY384p, GLY389p, GLY407p, GLY407q, GLY677q, GLY719q, HIS229q, HIS255p, HIS291q, HIS359q, ILE240q, ILE260p, ILE319p, ILE319q, ILE333q, ILE373q, ILE671p, LEU249q, LEU256p, LEU337p, LEU337q, LEU381p, LEU396p, LEU404p, LEU720q, LYS258p, LYS258q, LYS322q, LYS650p, LYS666p, LYS707q, MET372q, MET403p, PHE274p, PHE292q, PHE317q, PHE344p, PHE366q, PHE371q, PHE393p, PHE399p, PHE410p, PHE662p, PHE667p, PHE670p, PHE713q, PRO250q, PRO279p, PRO294q, PRO364q, PRO367q, PRO374q, PRO400p, PRO653p, PRO655p, PRO658p, PRO659p, SER225q, SER232q, SER243q, SER261p, SER277p, SER293q, SER339p, SER385p, SER391p, SER392p, SER401p, SER663p, SER669p, SER675q, SER703q, SER708q, THR233q, THR241q, THR242q, THR244q, THR246q, THR251q, THR278p, THR325p, THR325q, THR326p, THR326q, THR331q, THR332q, THR338p, THR340p, THR380p, THR406p, THR406q, THR652p, THR665p, THR672p, THR672q, THR676q, THR702q, THR714q, THR722q, TRP228q, TRP234q, TRP247q, TRP280p, TRP297q, TYR252q, TYR257p, TYR276p, TYR282q, TYR376q, TYR378p, TYR394p, TYR398p, TYR674q, TYR705q, TYR721q, VAL221p, VAL221q, VAL321p, VAL321q, VAL324q, VAL330q, VAL341p, VAL343p, VAL370q, VAL388p, VAL654p, VAL711q, VAL715q
• p-r: ARG405p, GLY222r, LEU337p, LEU337r, THR338p
• p-s: ARG405s, GLY222p, LEU337p, LEU337s, THR338s
• q-r: ALA218q, ALA224r, ALA248r, ALA263q, ALA334q, ALA334r, ALA368r, ALA387q, ALA548r, ALA656q, ALA660q, ALA664q, ALA668q, ALA706r, ALA709r, ARG245r, ARG287r, ARG295r, ARG299r, ARG390q, ARG405q, ARG405r, ASN223q, ASN223r, ASN227r, ASN253q, ASN253r, ASN254r, ASN318r, ASN327q, ASN335q, ASN335r, ASN336q, ASN336r, ASN382q, ASN383q, ASN408q, ASN408r, ASN409q, ASN409r, ASN651r, ASN657q, ASN704r, ASN710r, ASN717r, ASN718r, ASP219q, ASP219r, ASP231r, ASP296r, ASP328q, ASP369r, ASP712r, ASP716-6.7485323.182206, ASP716r, CYS230r, CYS290r, CYS362r, CYS395q, GLN259q, GLN320r, GLN342q, GLN350q, GLN360r, GLN375r, GLN386q, GLN402q, GLN673q, GLN673r, GLN678r, GLU323q, GLU323r, GLU348q, GLU397q, GLU546r, GLU661q, GLY217q, GLY220q, GLY220r, GLY222-7.2360752.946953, GLY222q, GLY222r, GLY226r, GLY275q, GLY281r, GLY329r, GLY361r, GLY384q, GLY389q, GLY407q, GLY407r, GLY677r, GLY719-3.1086032.543409, GLY719r, HIS229r, HIS255q, HIS291r, HIS359r, ILE240r, ILE260q, ILE319-2.6526413.236165, ILE319q, ILE319r, ILE333r, ILE373r, ILE671q, LEU249r, LEU256q, LEU337q, LEU337r, LEU381q, LEU396q, LEU404q, LEU720r, LYS258q, LYS258r, LYS322r, LYS650q, LYS666q, LYS707r, MET372r, MET403q, PHE274q, PHE292r, PHE317r, PHE344q, PHE366r, PHE371r, PHE393q, PHE399q, PHE410q, PHE662q, PHE667q, PHE670q, PHE713r, PRO250r, PRO279q, PRO294r, PRO364r, PRO365r, PRO367r, PRO374r, PRO400q, PRO653q, PRO655q, PRO658q, PRO659q, SER225r, SER232r, SER243r, SER261q, SER277q, SER293r, SER339q, SER385q, SER391q, SER392q, SER401q, SER663q, SER669q, SER675r, SER703r, SER708-10.1882782.889916, SER708-7.4832953.070271, SER708r, THR233r, THR241r, THR242r, THR244r, THR246r, THR251r, THR278q, THR325q, THR325r, THR326q, THR326r, THR331r, THR332q, THR332r, THR338q, THR340q, THR380q, THR406-2.5247113.124796, THR406-4.7109492.905048, THR406q, THR406r, THR652q, THR665q, THR672q, THR672r, THR676r, THR702r, THR714r, THR722r, TRP228-10.9481602.836730, TRP228-9.3308732.918662, TRP228r, TRP234r, TRP247r, TRP280q, TRP297r, TYR252r, TYR257q, TYR276q, TYR282r, TYR376r, TYR378q, TYR394q, TYR398q, TYR674r, TYR705-10.4106332.935011, TYR705r, TYR721r, VAL221-2.2642792.848023, VAL221q, VAL221r, VAL239r, VAL321q, VAL321r, VAL324r, VAL330r, VAL341q, VAL343q, VAL370r, VAL388q, VAL654q, VAL711r, VAL715r
• q-s: ARG405q, GLY222s, LEU337q, LEU337s, THR338q
• r-s: ALA218r, ALA224s, ALA248s, ALA263r, ALA334r, ALA334s, ALA368s, ALA387-10.7227822.797779, ALA387-8.0284222.988687, ALA387r, ALA548s, ALA656r, ALA660r, ALA664r, ALA668r, ALA706s, ALA709s, ARG245s, ARG287s, ARG295s, ARG299s, ARG390r, ARG405-2.1181273.255907, ARG405-2.9252193.102890, ARG405-3.8086333.109376, ARG405-5.3768672.824514, ARG405r, ARG405s, ASN223r, ASN223s, ASN227s, ASN253r, ASN253s, ASN254s, ASN318s, ASN327r, ASN335r, ASN335s, ASN336r, ASN336s, ASN382r, ASN383r, ASN408r, ASN408s, ASN409r, ASN409s, ASN651s, ASN657r, ASN704s, ASN710s, ASN717s, ASN718s, ASP219r, ASP219s, ASP231s, ASP296s, ASP328r, ASP369s, ASP712s, ASP716s, CYS230s, CYS290s, CYS362s, CYS395r, GLN259-8.3885383.035570, GLN259r, GLN320s, GLN342r, GLN350r, GLN360s, GLN375s, GLN386r, GLN402r, GLN673r, GLN673s, GLN678s, GLU323r, GLU323s, GLU348r, GLU397r, GLU546s, GLU661r, GLY217r, GLY220r, GLY220s, GLY222r, GLY222s, GLY226s, GLY275r, GLY281s, GLY329s, GLY361s, GLY384r, GLY389-8.4847993.076027, GLY389r, GLY407-7.7252342.875744, GLY407r, GLY407s, GLY677s, GLY719s, HIS229s, HIS255r, HIS291s, HIS359s, ILE240s, ILE260r, ILE319r, ILE319s, ILE333s, ILE373s, ILE671r, LEU249s, LEU256r, LEU337r, LEU337s, LEU381r, LEU396r, LEU404r, LEU720s, LYS258r, LYS258s, LYS322s, LYS650r, LYS666-3.0746902.548201, LYS666r, LYS707s, MET372s, MET403-4.1771493.237752, MET403r, PHE274r, PHE292s, PHE317s, PHE344r, PHE366s, PHE371s, PHE393r, PHE399r, PHE410r, PHE662r, PHE667r, PHE670r, PHE713s, PRO250s, PRO279r, PRO294s, PRO364s, PRO367s, PRO374s, PRO400r, PRO653r, PRO655-15.9291412.587913, PRO655r, PRO658r, PRO659r, SER225s, SER232s, SER243s, SER261r, SER277r, SER293s, SER339r, SER385r, SER391r, SER392r, SER401-10.0477672.889735, SER401-11.0000302.810240, SER401r, SER663r, SER669r, SER675s, SER703s, SER708s, THR233s, THR241s, THR242s, THR244s, THR246s, THR251s, THR278r, THR325r, THR325s, THR326r, THR326s, THR331s, THR332s, THR338r, THR340r, THR380r, THR406r, THR406s, THR652r, THR665r, THR672r, THR672s, THR676s, THR702s, THR714s, THR722s, TRP228s, TRP234s, TRP247s, TRP280r, TRP297s, TYR252s, TYR257r, TYR276r, TYR282s, TYR376s, TYR378r, TYR394r, TYR398r, TYR674s, TYR705s, TYR721s, VAL221r, VAL221s, VAL239s, VAL321r, VAL321s, VAL324s, VAL330s, VAL341r, VAL343r, VAL370s, VAL388r, VAL654r, VAL711s, VAL715s
• r-t: ALA664r, ARG465t, ASN436t, ASP440t, GLN441t, GLU661r, ILE439t, LEU438t, PHE662r, SER663r, THR665r, TYR442t
• s-t: ALA267s, ALA358s, ALA426t, ALA456t, ALA469t, ALA506s, ALA523s, ALA525t, ALA548s, ALA550s, ALA554s, ALA568t, ALA573s, ALA581t, ALA592t, ALA601s, ALA601t, ALA620s, ARG287s, ARG390s, ARG433t, ARG448t, ARG465t, ARG485s, ARG485t, ARG488s, ARG514s, ARG576s, ARG576t, ARG610s, ARG610t, ARG694t, ARG730t, ARG734t, ASN253s, ASN269s, ASN271s, ASN286s, ASN302t, ASN382s, ASN383s, ASN436t, ASN447t, ASN451t, ASN458t, ASN477t, ASN496s, ASN497s, ASN498s, ASN500s, ASN510s, ASN510t, ASN512s, ASN519s, ASN552s, ASN557s, ASN570s, ASN570t, ASN583t, ASN691t, ASN696t, ASP270s, ASP284s, ASP346s, ASP432t, ASP440t, ASP460t, ASP495s, ASP529t, ASP530t, ASP556s, ASP590t, ASP595s, ASP595t, ASP609s, ASP609t, ASP611t, ASP626s, CYS362s, CYS395s, CYS483s, GLN350s, GLN360s, GLN375s, GLN386s, GLN429t, GLN441t, GLN450t, GLN452t, GLN457t, GLN474t, GLN486s, GLN487s, GLN585t, GLN608s, GLN608t, GLN615s, GLN646s, GLN688t, GLN700t, GLU348s, GLU397s, GLU515s, GLU546s, GLU564t, GLU565t, GLU575s, GLU575t, GLU698t, GLY266s, GLY275s, GLY281s, GLY306t, GLY356s, GLY361s, GLY377s, GLY384s, GLY389s, GLY466t, GLY470t, GLY481s, GLY481t, GLY505s, GLY513s, GLY521s, GLY539s, GLY544s, GLY549s, GLY578t, GLY594t, GLY600s, GLY600t, GLY604t, GLY616s, GLY627s, GLY627t, GLY636s, GLY637s, GLY637t, GLY639s, HIS272s, HIS289s, HIS359s, HIS422t, HIS427t, HIS527t, HIS597s, HIS597t, HIS624s, HIS628s, HIS628t, HIS630s, HIS630t, ILE260s, ILE373s, ILE439t, ILE517s, ILE518s, ILE542s, ILE560s, ILE566t, ILE618s, ILE622s, LEU351s, LEU355s, LEU379s, LEU381s, LEU396s, LEU431t, LEU434t, LEU438t, LEU443t, LEU446t, LEU461t, LEU462t, LEU479t, LEU511s, LEU555s, LEU584s, LEU584t, LEU602s, LEU602t, LEU634s, LEU640s, LEU732t, LEU736t, LYS258s, LYS459t, LYS476t, LYS491s, LYS493s, LYS508s, LYS528s, LYS528t, LYS531s, LYS531t, LYS533s, LYS545s, LYS567t, LYS621s, LYS693t, MET435t, MET471t, MET524s, MET537s, MET541s, MET559s, MET599s, MET599t, MET605s, MET605t, MET635s, PHE274s, PHE288s, PHE344s, PHE393s, PHE399s, PHE421t, PHE463t, PHE501s, PHE534s, PHE535s, PHE543s, PHE577t, PHE629s, PHE629t, PHE638s, PRO279s, PRO352s, PRO374s, PRO400s, PRO420t, PRO437t, PRO468t, PRO475t, PRO480t, PRO482s, PRO482t, PRO520s, PRO536s, PRO571t, PRO591t, PRO603s, PRO603t, PRO617s, PRO623s, PRO631s, PRO633s, PRO697t, PRO735t, SER261s, SER262s, SER268s, SER277s, SER357s, SER385s, SER391s, SER392s, SER423t, SER424t, SER428t, SER430t, SER464t, SER467t, SER472t, SER490s, SER499s, SER507s, SER516s, SER538s, SER547s, SER551s, SER586t, SER587t, SER588t, SER632s, SER632t, SER692t, THR265s, THR278s, THR380s, THR449t, THR492s, THR494s, THR502s, THR504s, THR522s, THR553s, THR561s, THR569t, THR574s, THR574t, THR579t, THR589t, THR593t, THR625s, THR729t, THR733t, TRP280s, TRP305t, TRP478t, TRP503s, TRP607s, TRP607t, TRP619s, TRP695t, TYR252s, TYR273s, TYR276s, TYR282s, TYR349s, TYR353s, TYR376s, TYR378s, TYR394s, TYR398s, TYR425t, TYR442t, TYR444t, TYR445t, TYR484s, TYR509s, TYR613s, TYR701t, TYR731t, VAL354s, VAL388s, VAL473t, VAL489s, VAL540s, VAL558s, VAL572s, VAL572t, VAL580t, VAL582t, VAL596s, VAL596t, VAL598s, VAL598t, VAL606t, VAL699t
• t-u: ALA218t, ALA224u, ALA248u, ALA263t, ALA334t, ALA334u, ALA368u, ALA387t, ALA548u, ALA656t, ALA660t, ALA664t, ALA668t, ALA706u, ALA709u, ARG245u, ARG287u, ARG295u, ARG299u, ARG390t, ARG405t, ARG405u, ASN223t, ASN223u, ASN227u, ASN253t, ASN253u, ASN254u, ASN318u, ASN327t, ASN335t, ASN335u, ASN336t, ASN336u, ASN382t, ASN383t, ASN408t, ASN408u, ASN409t, ASN409u, ASN651u, ASN657t, ASN704u, ASN710u, ASN717u, ASN718u, ASP219t, ASP219u, ASP231u, ASP296u, ASP328t, ASP369u, ASP712u, ASP716u, CYS230u, CYS290u, CYS362u, CYS395t, GLN259t, GLN320u, GLN342t, GLN350t, GLN360u, GLN375u, GLN386t, GLN402t, GLN673t, GLN673u, GLN678u, GLU323t, GLU323u, GLU348t, GLU397t, GLU546u, GLU661t, GLY217t, GLY220t, GLY220u, GLY222t, GLY222u, GLY226u, GLY275t, GLY281u, GLY329u, GLY361u, GLY384t, GLY389t, GLY407t, GLY407u, GLY677u, GLY719u, HIS229u, HIS255t, HIS291u, HIS359u, ILE240u, ILE260t, ILE319u, ILE333u, ILE373u, ILE671t, LEU249u, LEU256t, LEU337t, LEU337u, LEU381t, LEU396t, LEU404t, LEU720u, LYS258t, LYS258u, LYS322u, LYS650t, LYS666t, LYS707u, MET372u, MET403t, PHE274t, PHE292u, PHE317u, PHE344t, PHE366u, PHE371u, PHE393t, PHE399t, PHE410t, PHE662t, PHE667t, PHE670t, PHE713u, PRO250u, PRO279t, PRO294u, PRO364u, PRO367u, PRO374u, PRO400t, PRO653t, PRO655t, PRO658t, PRO659t, SER225u, SER232u, SER243u, SER261t, SER277t, SER293u, SER339t, SER385t, SER391t, SER392t, SER401t, SER663t, SER669t, SER675u, SER703u, SER708u, THR233u, THR241u, THR242u, THR244u, THR246u, THR251u, THR278t, THR325t, THR325u, THR326t, THR326u, THR331u, THR332t, THR332u, THR338t, THR340t, THR380t, THR406t, THR406u, THR652t, THR665t, THR672t, THR672u, THR676u, THR702u, THR714u, THR722u, TRP228u, TRP234u, TRP247u, TRP280t, TRP297u, TYR252u, TYR257t, TYR276t, TYR282u, TYR376u, TYR378t, TYR394t, TYR398t, TYR674u, TYR705u, TYR721u, VAL221t, VAL221u, VAL239u, VAL321t, VAL321u, VAL324u, VAL330u, VAL341t, VAL343t, VAL370u, VAL388t, VAL654t, VAL711u, VAL715u
• t-v: ARG405t, GLY222v, LEU337t, LEU337v, THR338t
• t-w: ARG405w, GLY222t, LEU337t, LEU337w, THR338w
• t-x: ALA218x, ALA224t, ALA248t, ALA263x, ALA334t, ALA334x, ALA368t, ALA387x, ALA548t, ALA656x, ALA660x, ALA664x, ALA668x, ALA706t, ALA709t, ARG245t, ARG287t, ARG295t, ARG299t, ARG390x, ARG405t, ARG405x, ASN223t, ASN223x, ASN227t, ASN253t, ASN253x, ASN254t, ASN318t, ASN327x, ASN335t, ASN335x, ASN336t, ASN336x, ASN382x, ASN383x, ASN408t, ASN408x, ASN409x, ASN651t, ASN657x, ASN704t, ASN710t, ASN717t, ASN718t, ASP219t, ASP219x, ASP231t, ASP296t, ASP328x, ASP369t, ASP712t, ASP716t, CYS230t, CYS290t, CYS362t, CYS395x, GLN259x, GLN320t, GLN342x, GLN350x, GLN360t, GLN375t, GLN386x, GLN402x, GLN673t, GLN673x, GLN678t, GLU323t, GLU323x, GLU348x, GLU397x, GLU546t, GLU661x, GLY217x, GLY220t, GLY220x, GLY222t, GLY222x, GLY226t, GLY275x, GLY281t, GLY329t, GLY361t, GLY384x, GLY389x, GLY407t, GLY407x, GLY677t, GLY719t, HIS229t, HIS255x, HIS291t, HIS359t, ILE240t, ILE260x, ILE319t, ILE319x, ILE333t, ILE373t, ILE671x, LEU249t, LEU256x, LEU337t, LEU337x, LEU381x, LEU396x, LEU404x, LEU720t, LYS258t, LYS258x, LYS322t, LYS650x, LYS666x, LYS707t, MET372t, MET403x, PHE274x, PHE292t, PHE317t, PHE344x, PHE366t, PHE371t, PHE393x, PHE399x, PHE410x, PHE662x, PHE667x, PHE670x, PHE713t, PRO250t, PRO279x, PRO294t, PRO364t, PRO365t, PRO367t, PRO374t, PRO400x, PRO653x, PRO655x, PRO658x, PRO659x, SER225t, SER232t, SER243t, SER261x, SER277x, SER293t, SER339x, SER385x, SER391x, SER392x, SER401x, SER663x, SER669x, SER675t, SER703t, SER708t, THR233t, THR241t, THR242t, THR244t, THR246t, THR251t, THR278x, THR325t, THR325x, THR326t, THR326x, THR331t, THR332t, THR332x, THR338x, THR340x, THR380x, THR406t, THR406x, THR652x, THR665x, THR672t, THR672x, THR676t, THR702t, THR714t, THR722t, TRP228t, TRP234t, TRP247t, TRP280x, TRP297t, TYR252t, TYR257x, TYR276x, TYR282t, TYR376t, TYR378x, TYR394x, TYR398x, TYR674t, TYR705t, TYR721t, VAL221t, VAL221x, VAL239t, VAL321t, VAL321x, VAL324t, VAL330t, VAL341x, VAL343x, VAL370t, VAL388x, VAL654x, VAL711t, VAL715t
• u-v: ALA218u, ALA224v, ALA248v, ALA263u, ALA334u, ALA334v, ALA368v, ALA387u, ALA548v, ALA656u, ALA660u, ALA664u, ALA668u, ALA706v, ALA709v, ARG245v, ARG287v, ARG295v, ARG299v, ARG390u, ARG405u, ARG405v, ASN223u, ASN223v, ASN227v, ASN253u, ASN253v, ASN254v, ASN318v, ASN327u, ASN335u, ASN335v, ASN336u, ASN336v, ASN382u, ASN383u, ASN408u, ASN408v, ASN409u, ASN409v, ASN651v, ASN657u, ASN704v, ASN710v, ASN717v, ASN718v, ASP219u, ASP219v, ASP231v, ASP296v, ASP328u, ASP369v, ASP712v, ASP716v, CYS230v, CYS290v, CYS362v, CYS395u, GLN259u, GLN320v, GLN342u, GLN350u, GLN360v, GLN375v, GLN386u, GLN402u, GLN673u, GLN673v, GLN678v, GLU323u, GLU323v, GLU348u, GLU397u, GLU546v, GLU661u, GLY217u, GLY220u, GLY220v, GLY222u, GLY222v, GLY226v, GLY275u, GLY281v, GLY329v, GLY361v, GLY384u, GLY389u, GLY407u, GLY407v, GLY677v, GLY719v, HIS229v, HIS255u, HIS291v, HIS359v, ILE240v, ILE260u, ILE319u, ILE319v, ILE333v, ILE373v, ILE671u, LEU249v, LEU256u, LEU337u, LEU337v, LEU381u, LEU396u, LEU404u, LEU720v, LYS258u, LYS258v, LYS322v, LYS650u, LYS666u, LYS707v, MET372v, MET403u, PHE274u, PHE292v, PHE317v, PHE344u, PHE366v, PHE371v, PHE393u, PHE399u, PHE410u, PHE662u, PHE667u, PHE670u, PHE713v, PRO250v, PRO279u, PRO294v, PRO364v, PRO367v, PRO374v, PRO400u, PRO653u, PRO655u, PRO658u, PRO659u, SER225v, SER232v, SER243v, SER261u, SER277u, SER293v, SER339u, SER385u, SER391u, SER392u, SER401u, SER663u, SER669u, SER675v, SER703v, SER708v, THR233v, THR241v, THR242v, THR244v, THR246v, THR251v, THR278u, THR325u, THR325v, THR326u, THR326v, THR331v, THR332u, THR332v, THR338u, THR340u, THR380u, THR406u, THR406v, THR652u, THR665u, THR672u, THR672v, THR676v, THR702v, THR714v, THR722v, TRP228v, TRP234v, TRP247v, TRP280u, TRP297v, TYR252v, TYR257u, TYR276u, TYR282v, TYR376v, TYR378u, TYR394u, TYR398u, TYR674v, TYR705v, TYR721v, VAL221u, VAL221v, VAL239v, VAL321u, VAL321v, VAL324v, VAL330v, VAL341u, VAL343u, VAL370v, VAL388u, VAL654u, VAL711v, VAL715v
• u-w: ARG405u, GLY222w, LEU337u, LEU337w, THR338u
• u-x: ARG405x, GLY222u, LEU337u, LEU337x, THR338x
• v-w: ALA218v, ALA224w, ALA248w, ALA263v, ALA334v, ALA334w, ALA368w, ALA387v, ALA548w, ALA656v, ALA660v, ALA664v, ALA668v, ALA706w, ALA709w, ARG245w, ARG287w, ARG295w, ARG299w, ARG390v, ARG405v, ARG405w, ASN223v, ASN223w, ASN227w, ASN253v, ASN253w, ASN254w, ASN318w, ASN327v, ASN335v, ASN335w, ASN336v, ASN336w, ASN382v, ASN383v, ASN408v, ASN408w, ASN409v, ASN409w, ASN651w, ASN657v, ASN704w, ASN710w, ASN717w, ASN718w, ASP219v, ASP219w, ASP231w, ASP296w, ASP328v, ASP369w, ASP712w, ASP716w, CYS230w, CYS290w, CYS362w, CYS395v, GLN259v, GLN320w, GLN342v, GLN350v, GLN360w, GLN375w, GLN386v, GLN402v, GLN673v, GLN673w, GLN678w, GLU323v, GLU323w, GLU348v, GLU397v, GLU546w, GLU661v, GLY217v, GLY220v, GLY220w, GLY222v, GLY222w, GLY226w, GLY275v, GLY281w, GLY329w, GLY361w, GLY384v, GLY389v, GLY407v, GLY407w, GLY677w, GLY719w, HIS229w, HIS255v, HIS291w, HIS359w, ILE240w, ILE260v, ILE319v, ILE319w, ILE333w, ILE373w, ILE671v, LEU249w, LEU256v, LEU337v, LEU337w, LEU381v, LEU396v, LEU404v, LEU720w, LYS258v, LYS258w, LYS322w, LYS650v, LYS666v, LYS707w, MET372w, MET403v, PHE274v, PHE292w, PHE317w, PHE344v, PHE366w, PHE371w, PHE393v, PHE399v, PHE410v, PHE662v, PHE667v, PHE670v, PHE713w, PRO250w, PRO279v, PRO294w, PRO364w, PRO367w, PRO374w, PRO400v, PRO653v, PRO655v, PRO658v, PRO659v, SER225w, SER232w, SER243w, SER261v, SER277v, SER293w, SER339v, SER385v, SER391v, SER392v, SER401v, SER663v, SER669v, SER675w, SER703w, SER708w, THR233w, THR241w, THR242w, THR244w, THR246w, THR251w, THR278v, THR325v, THR325w, THR326v, THR326w, THR331w, THR332v, THR332w, THR338v, THR340v, THR380v, THR406v, THR406w, THR652v, THR665v, THR672v, THR672w, THR676w, THR702w, THR714w, THR722w, TRP228w, TRP234w, TRP247w, TRP280v, TRP297w, TYR252w, TYR257v, TYR276v, TYR282w, TYR376w, TYR378v, TYR394v, TYR398v, TYR674w, TYR705w, TYR721w, VAL221v, VAL221w, VAL239w, VAL321v, VAL321w, VAL324w, VAL330w, VAL341v, VAL343v, VAL370w, VAL388v, VAL654v, VAL711w, VAL715w
• v-x: ARG405v, GLY222x, LEU337v, LEU337x, THR338v
• w-x: ALA218w, ALA224x, ALA248x, ALA263w, ALA334w, ALA334x, ALA368x, ALA387w, ALA548x, ALA656w, ALA660w, ALA664w, ALA668w, ALA706x, ALA709x, ARG245x, ARG287x, ARG295x, ARG299x, ARG390w, ARG405w, ARG405x, ASN223w, ASN223x, ASN227x, ASN253w, ASN253x, ASN254x, ASN318x, ASN327w, ASN335w, ASN335x, ASN336w, ASN336x, ASN382w, ASN383w, ASN408w, ASN408x, ASN409w, ASN651x, ASN657w, ASN704x, ASN710x, ASN717x, ASN718x, ASP219w, ASP219x, ASP231x, ASP296x, ASP328w, ASP369x, ASP712x, ASP716x, CYS230x, CYS290x, CYS362x, CYS395w, GLN259w, GLN320x, GLN342w, GLN350w, GLN360x, GLN375x, GLN386w, GLN402w, GLN673w, GLN673x, GLN678x, GLU323w, GLU323x, GLU348w, GLU397w, GLU546x, GLU661w, GLY217w, GLY220w, GLY220x, GLY222w, GLY222x, GLY226x, GLY275w, GLY281x, GLY329x, GLY361x, GLY384w, GLY389w, GLY407w, GLY407x, GLY677x, GLY719x, HIS229x, HIS255w, HIS291x, HIS359x, ILE240x, ILE260w, ILE319x, ILE333x, ILE373x, ILE671w, LEU249x, LEU256w, LEU337w, LEU337x, LEU381w, LEU396w, LEU404w, LEU720x, LYS258w, LYS258x, LYS322x, LYS650w, LYS666w, LYS707x, MET372x, MET403w, PHE274w, PHE292x, PHE317x, PHE344w, PHE366x, PHE371x, PHE393w, PHE399w, PHE410w, PHE662w, PHE667w, PHE670w, PHE713x, PRO250x, PRO279w, PRO294x, PRO364x, PRO367x, PRO374x, PRO400w, PRO653w, PRO655w, PRO658w, PRO659w, SER225x, SER232x, SER243x, SER261w, SER277w, SER293x, SER339w, SER385w, SER391w, SER392w, SER401w, SER663w, SER669w, SER675x, SER703x, SER708x, THR233x, THR241x, THR242x, THR244x, THR246x, THR251x, THR278w, THR325w, THR325x, THR326w, THR326x, THR331x, THR332w, THR332x, THR338w, THR340w, THR380w, THR406w, THR406x, THR652w, THR665w, THR672w, THR672x, THR676x, THR702x, THR714x, THR722x, TRP228x, TRP234x, TRP247x, TRP280w, TRP297x, TYR252x, TYR257w, TYR276w, TYR282x, TYR376x, TYR378w, TYR394w, TYR398w, TYR674x, TYR705x, TYR721x, VAL221w, VAL221x, VAL239x, VAL321w, VAL321x, VAL324x, VAL330x, VAL341w, VAL343w, VAL370x, VAL388w, VAL654w, VAL711x, VAL715x
• y-z: ALA218y, ALA224z, ALA248z, ALA263y, ALA334y, ALA334z, ALA368z, ALA387y, ALA548z, ALA656y, ALA660y, ALA664y, ALA668y, ALA706z, ALA709z, ARG245z, ARG287z, ARG295z, ARG299z, ARG390y, ARG405y, ARG405z, ASN223y, ASN223z, ASN227z, ASN253y, ASN253z, ASN254z, ASN318z, ASN327y, ASN335y, ASN335z, ASN336y, ASN336z, ASN382y, ASN383y, ASN408y, ASN408z, ASN409y, ASN409z, ASN651z, ASN657y, ASN704z, ASN710z, ASN717z, ASN718z, ASP219y, ASP219z, ASP231z, ASP296z, ASP328y, ASP369z, ASP712z, ASP716z, CYS230z, CYS290z, CYS362z, CYS395y, GLN259y, GLN320z, GLN342y, GLN350y, GLN360z, GLN375z, GLN386y, GLN402y, GLN673y, GLN673z, GLN678z, GLU323y, GLU323z, GLU348y, GLU397y, GLU546z, GLU661y, GLY217y, GLY220y, GLY220z, GLY222y, GLY222z, GLY226z, GLY275y, GLY281z, GLY329z, GLY361z, GLY384y, GLY389y, GLY407y, GLY407z, GLY677z, GLY719z, HIS229z, HIS255y, HIS291z, HIS359z, ILE240z, ILE260y, ILE319z, ILE333z, ILE373z, ILE671y, LEU249z, LEU256y, LEU337y, LEU337z, LEU381y, LEU396y, LEU404y, LEU720z, LYS258y, LYS258z, LYS322z, LYS650y, LYS666y, LYS707z, MET372z, MET403y, PHE274y, PHE292z, PHE317z, PHE344y, PHE366z, PHE371z, PHE393y, PHE399y, PHE410y, PHE662y, PHE667y, PHE670y, PHE713z, PRO250z, PRO279y, PRO294z, PRO364z, PRO365z, PRO367z, PRO374z, PRO400y, PRO653y, PRO655y, PRO658y, PRO659y, SER225z, SER232z, SER243z, SER261y, SER277y, SER293z, SER339y, SER385y, SER391y, SER392y, SER401y, SER663y, SER669y, SER675z, SER703z, SER708z, THR233z, THR241z, THR242z, THR244z, THR246z, THR251z, THR278y, THR325y, THR325z, THR326y, THR326z, THR331z, THR332z, THR338y, THR340y, THR380y, THR406y, THR406z, THR652y, THR665y, THR672y, THR672z, THR676z, THR702z, THR714z, THR722z, TRP228z, TRP234z, TRP247z, TRP280y, TRP297z, TYR252z, TYR257y, TYR276y, TYR282z, TYR376z, TYR378y, TYR394y, TYR398y, TYR674z, TYR705z, TYR721z, VAL221y, VAL221z, VAL321y, VAL321z, VAL324z, VAL330z, VAL341y, VAL343y, VAL370z, VAL388y, VAL654y, VAL711z, VAL715z
• y-0: ARG405y, GLY2220, LEU3370, LEU337y, THR338y
• y-2: ALA3872, ARG245y, ARG4052, ASN335y, ASP2192, ASP219y, ASP369y, ASP716y, GLN2592, GLU3972, GLU546y, GLY222y, GLY3892, GLY4072, GLY719y, ILE319y, LYS2582, LYS6662, SER4012, SER708y, THR3382, THR406y, TRP228y, TYR705y
• y-3: ARG2953, ARG295y, ARG2993, ARG299y, ARG6943, ARG694y, ASN3033, ASN303y, ASP2313, ASP231y, ASP5293, ASP529y, ASP5303, ASP530y, GLN2983, GLN298y, GLN700y, GLU6903, GLU690y, GLU6983, GLU698y, LYS6933, LYS693y, LYS7073, LYS707y, SER7033, SER703y, THR7023, TRP6953, TRP695y
• y-7: ALA3587, ALA5507, ALA6017, ALA601y, ARG3907, ARG433y, ARG465y, ARG5147, ARG576y, ARG694y, ARG734y, ASN2717, ASN436y, ASN477y, ASN4967, ASN4977, ASN4987, ASN5007, ASN5107, ASN583y, ASP2707, ASP3467, ASP432y, ASP440y, ASP460y, ASP4957, ASP529y, ASP609y, ASP611y, ASP6267, GLN3607, GLN3757, GLN450y, GLN4877, GLN585y, GLU3487, GLU5157, GLU564y, GLU565y, GLU575y, GLU698y, GLY3567, GLY3897, GLY604y, GLY6277, HIS2727, HIS3597, HIS422y, HIS427y, HIS6247, HIS6287, HIS630y, ILE5177, ILE5427, LEU6347, LEU736y, LYS459y, LYS4937, LYS5087, LYS528y, LYS693y, MET605y, MET6357, PHE3937, PHE463y, PHE577y, PHE6297, SER3917, SER3927, SER428y, SER472y, SER4997, SER587y, THR3807, THR449y, THR4947, THR5537, THR579y, TRP607y, TRP695y, TYR3987, TYR442y, TYR444y
• z-0: ALA218z, ALA2240, ALA2480, ALA3340, ALA334z, ALA3680, ALA387z, ALA656z, ALA660z, ALA664z, ALA668z, ARG2450, ARG2870, ARG2950, ARG2990, ARG4050, ARG405z, ASN2230, ASN223z, ASN2270, ASN2530, ASN2540, ASN3180, ASN327z, ASN3350, ASN335z, ASN3360, ASN336z, ASN4080, ASN408z, ASN4090, ASN409z, ASN657z, ASP2190, ASP219z, ASP2310, ASP2960, ASP328z, ASP3690, ASP7160, CYS2300, CYS2900, CYS3620, CYS395z, GLN259z, GLN3200, GLN342z, GLN350z, GLN3600, GLN3750, GLN402z, GLN673z, GLU3230, GLU323z, GLU348z, GLU397z, GLU5460, GLU661z, GLY217z, GLY2200, GLY220z, GLY2220, GLY222z, GLY2260, GLY2810, GLY3290, GLY3610, GLY389z, GLY4070, GLY407z, GLY7190, HIS2290, HIS255z, HIS2910, HIS3590, ILE2400, ILE3190, ILE319z, ILE3330, ILE3730, ILE671z, LEU2490, LEU256z, LEU3370, LEU337z, LEU396z, LEU404z, LYS2580, LYS258z, LYS3220, LYS650z, LYS666z, MET3720, MET403z, PHE2920, PHE3170, PHE344z, PHE3660, PHE3710, PHE393z, PHE399z, PHE410z, PHE662z, PHE667z, PHE670z, PRO2500, PRO279z, PRO2940, PRO3640, PRO3650, PRO3670, PRO3740, PRO400z, PRO653z, PRO655z, PRO658z, PRO659z, SER2250, SER2320, SER2430, SER2930, SER339z, SER401z, SER663z, SER669z, SER7080, THR2330, THR2410, THR2420, THR2440, THR2460, THR2510, THR278z, THR3250, THR325z, THR3260, THR326z, THR3310, THR3320, THR338z, THR340z, THR4060, THR406z, THR652z, THR665z, THR672z, TRP2280, TRP2340, TRP2470, TRP280z, TRP2970, TYR2520, TYR257z, TYR2820, TYR3760, TYR394z, TYR398z, TYR7050, VAL2210, VAL221z, VAL3210, VAL321z, VAL3240, VAL3300, VAL341z, VAL343z, VAL3700, VAL654z
• 0-1: ALA3870, ARG2451, ARG4050, ASN2271, ASP2190, ASP2191, ASP3691, ASP7161, GLN2590, GLU3970, GLY2221, GLY3890, GLY4070, GLY7191, LYS2580, LYS6660, MET4030, SER4010, SER7081, THR4061, TRP2281, TYR7051, VAL2211
• 1-2: ALA3871, ARG2452, ARG4051, ASP2191, ASP2192, ASP3692, ASP7162, GLN2591, GLU3971, GLY2222, GLY3891, GLY4071, GLY7192, LYS2581, LYS6661, SER4011, SER7082, THR4062, TRP2282, TYR7052, VAL2212
• 2-3: ALA3582, ALA5502, ALA6012, ALA6013, ARG3902, ARG4333, ARG4653, ARG5142, ARG5763, ARG6943, ARG7343, ASN2712, ASN4363, ASN4773, ASN4962, ASN4972, ASN4982, ASN5002, ASN5102, ASN5833, ASP2702, ASP3462, ASP4323, ASP4403, ASP4603, ASP4952, ASP5293, ASP6093, ASP6113, ASP6262, GLN3602, GLN3752, GLN4503, GLN4872, GLN5853, GLU3482, GLU5152, GLU5643, GLU5653, GLU5753, GLU6983, GLY3562, GLY3892, GLY6043, GLY6272, HIS2722, HIS3592, HIS4223, HIS4273, HIS6242, HIS6282, HIS6303, ILE5172, ILE5422, LEU6342, LEU7363, LYS4593, LYS4932, LYS5082, LYS5283, LYS6933, MET6053, MET6352, PHE3932, PHE4633, PHE5773, PHE6292, SER3912, SER4723, SER4992, SER5873, THR4493, THR4942, THR5532, THR5793, TRP6073, TRP6953, TYR3982, TYR4423, TYR4443
• 3-4: ALA3873, ARG2454, ARG4053, ASN2274, ASP2193, ASP2194, ASP3694, ASP7164, GLN2593, GLU3973, GLU5464, GLY2224, GLY3893, GLY4073, GLY7194, ILE3194, LYS2583, LYS6663, MET4033, SER4013, SER7084, THR4064, TRP2284, TYR7054, VAL2214
• 3-7: ALA3877, ARG2453, ARG4057, ASN2273, ASN3353, ASP2193, ASP2197, ASP3693, ASP7163, GLN2597, GLU3977, GLY2223, GLY3897, GLY4077, GLY7193, ILE3193, LYS2587, LYS6667, MET4037, SER4017, SER7083, THR3387, TRP2283, TYR7053, VAL2213
• 4-5: ALA3874, ARG2455, ARG4054, ASP2194, ASP2195, ASP3695, ASP7165, GLN2594, GLU3974, GLU5465, GLY2225, GLY3894, GLY4074, GLY7195, ILE3195, LYS2584, LYS6664, PRO6554, SER4014, SER7085, THR4065, TRP2285, TYR6745, TYR7055, VAL2215
• 5-6: ALA3875, ARG2456, ARG4055, ASP2195, ASP2196, ASP3696, ASP7166, GLN2595, GLU3975, GLU5466, GLY2226, GLY3895, GLY4075, GLY7196, ILE3196, LYS2585, LYS6665, SER4015, SER7086, THR4066, TRP2286, TYR7056, VAL2216
• 6-7: ALA3876, ARG2457, ARG4056, ASN2277, ASP2196, ASP2197, ASP3697, ASP7167, GLN2596, GLU3976, GLY2227, GLY3896, GLY4076, GLY7197, LYS2586, LYS6666, MET4036, SER4016, SER7087, THR4067, TRP2287, TYR7057