1VT0

bacteriophage p22 portal protein bound to middle tail factor gp4. this file contain the second biological assembly

• Total interactions analyzed: 276
• Total true interactions: 84
• Strongest Interaction:
  • Chains: V-W
  • Int. Res.: 435
  • Norm. En. per Res.: -3.1517
• Hub Node: S(10)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
M-N	-138.7362	-202.5607	-994.988	-1336.2849	431	64	18	44425	16	196	180
M-O	-134.2755	-199.1413	-989.157	-1322.5738	432	61	17	44049	16	195	180
M-P	0.0	-2.1565	-2.166	-4.3225	21	0	0	274	0	4	7
M-V	0.0	-4.0124	-2.5938	-6.6062	21	0	0	313	0	4	7
M-k	-12.7861	8.283			6
M-l	-5.7048	-39.0298			15
M-m	-35.5131	18.149			8
M-n	-42.4165	-38.8109			13
N-O	0.0	-2.2539	-2.2552	-4.509	21	0	0	288	0	4	7
N-V	-144.4473	-197.2384	-992.46	-1334.1457	433	72	17	44655	16	195	183
N-W	0.0	-3.9787	-2.6313	-6.61	22	0	0	321	0	4	8
N-k	-39.3126	17.284			9
N-l	-43.3286	-39.9763			13
N-m	-6.0185	-36.8262			15
N-v	-14.2223	8.0929			6
O-P	-143.3092	-200.6065	-1011.58	-1355.4958	435	75	18	45605	16	201	183
O-Q	0.0	-2.6759	-2.1644	-4.8403	21	0	0	279	0	4	7
O-l	-36.4898	18.1814			8
O-m	-3.2446	8.353			3
O-n	-3.6498	-39.1167			15
O-o	-37.6149	-38.7217			13
P-Q	-135.2917	-200.6752	-998.772	-1334.739	433	69	18	44868	16	196	182
P-R	0.0	-4.7039	-2.2495	-6.9534	21	0	0	293	0	4	8
P-l	-10.8604	7.8766			7
P-n	-39.8733	17.0047			9
P-o	-5.8055	-36.6499			15
P-p	-36.3961	-38.5564			13
Q-R	-133.7948	-206.4898	-989.902	-1330.1866	435	73	17	44983	16	195	186
Q-X	0.0	-4.1937	-0.4905	-4.6843	12	0	0	81	0	2	5
Q-n	-17.7453	7.9177			8
Q-o	-38.5363	17.7662			8
Q-p	-6.3075	-36.6907			15
Q-r	-41.0445	-39.5698			18
R-U	0.0	-4.0307	-2.6346	-6.6653	21	0	0	313	0	4	7
R-X	-134.8868	-198.7855	-207.847	-541.5193	187	13	2	9901	2	81	77
R-o	-13.6273	8.2831			6
R-p	-35.142	18.4883			8
R-q	-41.5303	-38.6313			13
R-r	-3.6139	-38.8308			16
S-T	-133.8564	-201.7092	-991.993	-1327.5586	433	60	18	44636	16	200	182
S-U	-133.3643	-200.3568	-965.62	-1299.3411	429	53	17	43893	16	195	179
S-W	0.0	-2.1095	-2.1015	-4.211	21	0	0	274	0	4	7
S-X	0.0	-2.063	0.0	-2.063	3	0	0	0	0	0	0
S-q	-13.247	8.0728			6
S-s	-16.6755	-35.0442			17
S-t	-39.4741	17.5414			9
S-u	-36.388	-39.1244			13
T-U	0.0	-2.2393	-2.3091	-4.5484	20	0	0	286	0	4	6
T-V	0.0	-4.1597	-2.388	-6.5476	22	0	0	303	0	4	8
T-W	-131.2292	-196.4155	-993.584	-1321.2287	432	64	17	44449	16	193	180
T-s	-40.377	18.2186			9
T-t	-13.9063	8.2454			6
T-u	-7.8781	-38.0501			16
T-v	-36.5907	-38.8761			13
U-X	-139.3984	-200.9911	-417.041	-757.4305	263	20	4	20020	7	125	106
U-q	-39.3684	17.1127			10
U-r	-17.6893	8.023			10
U-s	-36.1142	-36.7985			13
U-t	-11.8301	-36.133			16
V-W	-148.67	-199.7394	-1022.6	-1371.0094	435	75	18	45227	16	193	182
V-k	-6.133	-36.5978			15
V-m	-37.2874	-35.9892			13
V-u	-14.6571	7.9708			6
V-v	-38.5722	17.5481			9
W-k	-34.9918	-37.2905			13
W-s	-15.1599	8.1618			6
W-u	-43.6526	17.9395			10
W-v	-7.2159	-38.6161			16
X-p	-6.6186	8.3298			5
X-q	-13.2027	-39.0414			18
X-r	-34.981	18.4161			8
X-t	-39.6147	-37.7386			13
k-m	-4.3166	85.95			16
k-v	0.0	85.3064			14
l-m	0.0	84.8124			14
l-n	-5.0873	84.2366			16
n-o	-3.343	86.286			16
o-p	-3.8367	87.6871			16
p-r	-3.3965	85.1468			16
q-r	-5.933	84.1708			16
q-t	-9.7121	87.1716			18
s-t	0.0	84.6631			14
s-u	-4.0697	85.3411			16
u-v	-4.5098	83.6656			16

Interface residues

• M-N: ALA107N, ALA110N, ALA17M, ALA195N, ALA21M, ALA338N, ALA342M, ALA342N, ALA357M, ALA390M, ALA390N, ALA400M, ALA402M, ALA402N, ALA407M, ALA408M, ALA411M, ALA416M, ALA424N, ALA431M, ALA442M, ALA572N, ALA86M, ALA90M, ALA91M, ARG103N, ARG116N, ARG145N, ARG146N, ARG14M, ARG171M, ARG269M, ARG26M, ARG273M, ARG274M, ARG27M, ARG321M, ARG328M, ARG330M, ARG330N, ARG343M, ARG343N, ARG376N, ARG37N, ARG441M, ARG511M, ARG513M, ARG532M, ARG532N, ARG54N, ARG569M, ARG569N, ARG61N, ARG65N, ARG72N, ARG81M, ARG87M, ARG99N, ASN105N, ASN112N, ASN141N, ASN161M, ASN182N, ASN203N, ASN205N, ASN31M, ASN337M, ASN337N, ASN366M, ASN366N, ASN375N, ASN380M, ASN394M, ASN394N, ASN401M, ASN401N, ASN426M, ASN436M, ASN439M, ASN452M, ASN531M, ASN531N, ASN573M, ASN6M, ASN74N, ASP131N, ASP134N, ASP159M, ASP166M, ASP169M, ASP16M, ASP186N, ASP196N, ASP206N, ASP215N, ASP23M, ASP312M, ASP325M, ASP339M, ASP339N, ASP364M, ASP364N, ASP367N, ASP368N, ASP378M, ASP383M, ASP383N, ASP421M, ASP42N, ASP433M, ASP43N, ASP443M, ASP519M, ASP561N, ASP570N, ASP58N, ASP84M, ASP89M, ASP92M, ASP92N, CYS516M, GLN135N, GLN142N, GLN181N, GLN214N, GLN218N, GLN270M, GLN327M, GLN327N, GLN355M, GLN355N, GLN387M, GLN387N, GLN399M, GLN399N, GLN40N, GLN429M, GLN437M, GLN525N, GLN529N, GLN530M, GLN530N, GLN544N, GLN550M, GLN555M, GLN555N, GLN56N, GLN575N, GLN591N, GLN73N, GLU117N, GLU120N, GLU133N, GLU147N, GLU185N, GLU189N, GLU227M, GLU230M, GLU24M, GLU28M, GLU296M, GLU306M, GLU311M, GLU314M, GLU317M, GLU354M, GLU360M, GLU379M, GLU393M, GLU393N, GLU396M, GLU396N, GLU406N, GLU414M, GLU423N, GLU445M, GLU495M, GLU515M, GLU534M, GLU537M, GLU548M, GLU548N, GLU566N, GLU585M, GLU588N, GLU5M, GLU70N, GLY183N, GLY305M, GLY308M, GLY318M, GLY326M, GLY358M, GLY365M, GLY365N, GLY382M, GLY382N, GLY419M, GLY427M, GLY428M, GLY512M, GLY545M, GLY55N, GLY562N, GLY564N, GLY580M, GLY85M, GLY96N, HIS104N, HIS150N, HIS155N, HIS172M, HIS177N, HIS361M, ILE109N, ILE113N, ILE119M, ILE149N, ILE176N, ILE217N, ILE271M, ILE333M, ILE333N, ILE340M, ILE340N, ILE356M, ILE356N, ILE510M, ILE535M, ILE535N, LEU164M, LEU212N, LEU322M, LEU329M, LEU33N, LEU373N, LEU374N, LEU384M, LEU384N, LEU389M, LEU389N, LEU405M, LEU405N, LEU418M, LEU438M, LEU444M, LEU453M, LEU536N, LEU538M, LEU539M, LEU539N, LEU551M, LEU552N, LEU553N, LEU554M, LEU559M, LEU559N, LEU560M, LEU560N, LEU576M, LEU67M, LEU67N, LEU79M, LYS108N, LYS163M, LYS167M, LYS190N, LYS229M, LYS248M, LYS272M, LYS30M, LYS313M, LYS324M, LYS346M, LYS346N, LYS347M, LYS347N, LYS348M, LYS348N, LYS413M, LYS413N, LYS528M, LYS528N, LYS541M, LYS563N, LYS574N, LYS582M, LYS583M, LYS66N, LYS83M, PHE187N, PHE209N, PHE222M, PHE309M, PHE336M, PHE350M, PHE351M, PHE351N, PHE359M, PHE359N, PHE35N, PHE432M, PHE449M, PHE524N, PHE557M, PHE557N, PHE57N, PRO137N, PRO148N, PRO204N, PRO210N, PRO302M, PRO345M, PRO345N, PRO349M, PRO349N, PRO353M, PRO370N, PRO385M, PRO385N, PRO388M, PRO388N, PRO395M, PRO395N, PRO398M, PRO398N, PRO543M, PRO547M, PRO587N, PRO62N, PRO75N, PRO82M, PRO88M, SER136N, SER13M, SER151N, SER154N, SER160M, SER162M, SER168M, SER178N, SER180N, SER22M, SER335N, SER36N, SER381M, SER39N, SER410M, SER523N, SER526N, SER69N, THR100N, THR106N, THR138N, THR20M, THR213N, THR216N, THR323M, THR344M, THR344N, THR377M, THR377N, THR386M, THR386N, THR409M, THR409N, THR417M, THR422M, THR434M, THR518M, THR542M, THR546M, THR558M, THR558N, TRP184N, TRP211N, TRP307M, TRP352M, TRP41N, TRP44N, TRP592N, TYR132N, TYR246M, TYR316M, TYR363M, TYR363N, TYR369N, TYR371N, TYR372N, TYR391M, TYR391N, TYR392M, TYR403M, TYR403N, TYR48N, TYR514M, TYR517M, TYR53N, TYR549N, TYR556N, TYR571N, TYR80M, VAL143N, VAL208N, VAL225M, VAL226M, VAL301M, VAL310M, VAL315M, VAL319M, VAL320M, VAL341N, VAL397M, VAL397N, VAL412M, VAL415M, VAL420M, VAL425M, VAL430M, VAL435M, VAL497M, VAL520M, VAL565N, VAL581M, VAL59N, VAL60N, VAL63M, VAL63N, VAL64N, VAL68N, VAL93M
• M-O: ALA107M, ALA110M, ALA17O, ALA195M, ALA21O, ALA338M, ALA342M, ALA342O, ALA357O, ALA390M, ALA390O, ALA400O, ALA402M, ALA402O, ALA407O, ALA408O, ALA411O, ALA416O, ALA424M, ALA431O, ALA442O, ALA572M, ALA86O, ALA90O, ALA91O, ARG103M, ARG116M, ARG145M, ARG146M, ARG14O, ARG171O, ARG269O, ARG26O, ARG273O, ARG274O, ARG27O, ARG321O, ARG328O, ARG330M, ARG330O, ARG343M, ARG343O, ARG376M, ARG37M, ARG441O, ARG511O, ARG513O, ARG532M, ARG532O, ARG54M, ARG569M, ARG569O, ARG61M, ARG65M, ARG72M, ARG81O, ARG87O, ARG99M, ASN105M, ASN112M, ASN141M, ASN161O, ASN182M, ASN203M, ASN205M, ASN31O, ASN337M, ASN337O, ASN366M, ASN366O, ASN375M, ASN380O, ASN394M, ASN394O, ASN401M, ASN401O, ASN426O, ASN436O, ASN439O, ASN452O, ASN531M, ASN531O, ASN573M, ASN573O, ASN6O, ASN74M, ASP131M, ASP134M, ASP159O, ASP166O, ASP169O, ASP16O, ASP186M, ASP196M, ASP206M, ASP215M, ASP23O, ASP312O, ASP325O, ASP339M, ASP339O, ASP364M, ASP364O, ASP367M, ASP368M, ASP378O, ASP383M, ASP383O, ASP421O, ASP42M, ASP433O, ASP43M, ASP443O, ASP519O, ASP561M, ASP570M, ASP58M, ASP84O, ASP89O, ASP92M, ASP92O, CYS516O, GLN135M, GLN142M, GLN181M, GLN214M, GLN218M, GLN270O, GLN327M, GLN327O, GLN355M, GLN355O, GLN387M, GLN387O, GLN399M, GLN399O, GLN40M, GLN429O, GLN437O, GLN525M, GLN529M, GLN530M, GLN530O, GLN544M, GLN550O, GLN555M, GLN555O, GLN56M, GLN575M, GLN591M, GLN73M, GLU117M, GLU120M, GLU133M, GLU147M, GLU185M, GLU189M, GLU227O, GLU230O, GLU24O, GLU28O, GLU296O, GLU306O, GLU311O, GLU314O, GLU317O, GLU354O, GLU360O, GLU379O, GLU393M, GLU393O, GLU396M, GLU396O, GLU406M, GLU414O, GLU423M, GLU445O, GLU495O, GLU515O, GLU534O, GLU537O, GLU548M, GLU548O, GLU566M, GLU585O, GLU588M, GLU595M, GLU5O, GLU70M, GLY183M, GLY305O, GLY308O, GLY318O, GLY326O, GLY358O, GLY365M, GLY365O, GLY382M, GLY382O, GLY419O, GLY427O, GLY428O, GLY512O, GLY545O, GLY55M, GLY562M, GLY564M, GLY580O, GLY85O, GLY96M, HIS104M, HIS150M, HIS155M, HIS172O, HIS177M, HIS361O, ILE109M, ILE113M, ILE119O, ILE149M, ILE176M, ILE217M, ILE271O, ILE333M, ILE333O, ILE340M, ILE340O, ILE356M, ILE356O, ILE510O, ILE535M, ILE535O, LEU164O, LEU212M, LEU322O, LEU329O, LEU33M, LEU373M, LEU374M, LEU384M, LEU384O, LEU389M, LEU389O, LEU405M, LEU405O, LEU418O, LEU438O, LEU444O, LEU453O, LEU536M, LEU538O, LEU539M, LEU539O, LEU551O, LEU552M, LEU553M, LEU554O, LEU559M, LEU560M, LEU560O, LEU576O, LEU67M, LEU67O, LEU79O, LYS108M, LYS163O, LYS167O, LYS190M, LYS229O, LYS248O, LYS272O, LYS30O, LYS313O, LYS324O, LYS346M, LYS346O, LYS347M, LYS347O, LYS348M, LYS348O, LYS413M, LYS413O, LYS528M, LYS528O, LYS541O, LYS563M, LYS574M, LYS582O, LYS583O, LYS66M, LYS83O, PHE187M, PHE209M, PHE222O, PHE309O, PHE336O, PHE350O, PHE351M, PHE351O, PHE359M, PHE359O, PHE35M, PHE432O, PHE449O, PHE524M, PHE557M, PHE557O, PHE57M, PRO137M, PRO148M, PRO204M, PRO210M, PRO302O, PRO345M, PRO345O, PRO349M, PRO349O, PRO353O, PRO370M, PRO385M, PRO385O, PRO388M, PRO388O, PRO395M, PRO395O, PRO398M, PRO398O, PRO543O, PRO547O, PRO587M, PRO62M, PRO75M, PRO82O, PRO88O, SER136M, SER13O, SER151M, SER154M, SER160O, SER162O, SER168O, SER178M, SER180M, SER22O, SER335M, SER36M, SER381O, SER39M, SER410O, SER523M, SER526M, SER69M, THR100M, THR106M, THR138M, THR20O, THR213M, THR216M, THR323O, THR344M, THR344O, THR377M, THR377O, THR386M, THR386O, THR409M, THR409O, THR417O, THR422O, THR434O, THR518O, THR542O, THR546O, THR558M, THR558O, TRP184M, TRP211M, TRP307O, TRP352O, TRP41M, TRP44M, TRP592M, TYR132M, TYR246O, TYR316O, TYR363M, TYR363O, TYR369M, TYR371M, TYR372M, TYR391M, TYR391O, TYR392O, TYR403M, TYR403O, TYR48M, TYR514O, TYR517O, TYR53M, TYR549M, TYR556M, TYR571M, TYR80O, VAL143M, VAL208M, VAL225O, VAL226O, VAL301O, VAL310O, VAL315O, VAL319O, VAL320O, VAL341M, VAL397M, VAL397O, VAL412O, VAL415O, VAL420O, VAL425O, VAL430O, VAL435O, VAL497O, VAL520O, VAL565M, VAL581O, VAL59M, VAL60M, VAL63M, VAL63O, VAL64M, VAL68M, VAL93O
• M-P: ALA86P, ARG343P, ASN366M, ASN394M, ASP339P, ASP367M, ASP368M, ASP84P, GLN399P, GLN52P, GLY85P, ILE340P, LYS563M, LYS83P, PRO345P, PRO370M, PRO88P, THR344P, TYR369M, TYR371M, TYR392P
• M-V: ALA86M, ARG343M, ASN366V, ASN394V, ASP339M, ASP367V, ASP368V, ASP84M, GLN399M, GLN52M, GLY85M, ILE340M, LYS563V, LYS83M, PRO345M, PRO370V, PRO88M, THR344M, TYR369V, TYR371V, TYR392M
• M-k: ARG131k, ARG54M, ASP325M, ASP339M, SER136k, TYR53M
• M-l: ARG122l, ARG125l, ARG90l, ASP364M, ASP378M, GLU112l, GLU354M, GLU360M, GLU379M, GLU46l, HIS361M, LYS108l, LYS111l, LYS124l, LYS52l
• M-m: ALA126m, ARG125m, ARG343M, ARG54M, ASN138m, GLY137m, TYR128m, TYR53M
• M-n: ARG125n, ARG376M, ASN380M, ASP367M, ASP368M, ASP378M, ASP383M, GLU112n, GLU379M, HIS85n, LYS102n, LYS108n, THR377M
• N-O: ALA86O, ARG343O, ASN366N, ASN394N, ASP339O, ASP367N, ASP368N, ASP84O, GLN399O, GLN52O, GLY85O, ILE340O, LYS563N, LYS83O, PRO345O, PRO370N, PRO88O, THR344O, TYR369N, TYR371N, TYR392O
• N-V: ALA107V, ALA110V, ALA17N, ALA195V, ALA21N, ALA338V, ALA342N, ALA342V, ALA357N, ALA390N, ALA390V, ALA400N, ALA402N, ALA402V, ALA407N, ALA408N, ALA411N, ALA416N, ALA424V, ALA431N, ALA442N, ALA572V, ALA86N, ALA90N, ALA91N, ARG103V, ARG116V, ARG145V, ARG146V, ARG14N, ARG171N, ARG269N, ARG26N, ARG273N, ARG274N, ARG275N, ARG27N, ARG321N, ARG328N, ARG330N, ARG330V, ARG343N, ARG343V, ARG376V, ARG37V, ARG441N, ARG511N, ARG513N, ARG532N, ARG532V, ARG54V, ARG569N, ARG569V, ARG61V, ARG65V, ARG72V, ARG81N, ARG87N, ARG99V, ASN105V, ASN112V, ASN141V, ASN161N, ASN182V, ASN203V, ASN205V, ASN31N, ASN337N, ASN337V, ASN366N, ASN366V, ASN375V, ASN380N, ASN394N, ASN394V, ASN401N, ASN401V, ASN426N, ASN436N, ASN439N, ASN452N, ASN531N, ASN531V, ASN573N, ASN573V, ASN6N, ASN74V, ASP131V, ASP134V, ASP159N, ASP166N, ASP169N, ASP16N, ASP186V, ASP196V, ASP206V, ASP215V, ASP23N, ASP312N, ASP325N, ASP339N, ASP339V, ASP364N, ASP364V, ASP367V, ASP368V, ASP378N, ASP383N, ASP383V, ASP421N, ASP42V, ASP433N, ASP43V, ASP443N, ASP519N, ASP561V, ASP570V, ASP58V, ASP84N, ASP89N, ASP92N, ASP92V, CYS516N, GLN135V, GLN142V, GLN181V, GLN214V, GLN218V, GLN270N, GLN327N, GLN327V, GLN355N, GLN355V, GLN387N, GLN387V, GLN399N, GLN399V, GLN40V, GLN429N, GLN437N, GLN525V, GLN529V, GLN530N, GLN530V, GLN544V, GLN550N, GLN555N, GLN555V, GLN56V, GLN575V, GLN591V, GLN73V, GLU117V, GLU120V, GLU133V, GLU147V, GLU185V, GLU189V, GLU227N, GLU230N, GLU24N, GLU28N, GLU296N, GLU306N, GLU311N, GLU314N, GLU317N, GLU354N, GLU360N, GLU379N, GLU393N, GLU393V, GLU396N, GLU396V, GLU406V, GLU414N, GLU423V, GLU445N, GLU462N, GLU495N, GLU515N, GLU534N, GLU537N, GLU548N, GLU548V, GLU566V, GLU585N, GLU588V, GLU595V, GLU5N, GLU70V, GLY183V, GLY305N, GLY308N, GLY318N, GLY326N, GLY365N, GLY365V, GLY382N, GLY382V, GLY419N, GLY427N, GLY428N, GLY512N, GLY545N, GLY55V, GLY562V, GLY564V, GLY580N, GLY85N, GLY96V, HIS104V, HIS150V, HIS155V, HIS172N, HIS177V, HIS361N, ILE109V, ILE113V, ILE119N, ILE149V, ILE176V, ILE217V, ILE271N, ILE333N, ILE333V, ILE340N, ILE340V, ILE356N, ILE356V, ILE510N, ILE535N, ILE535V, LEU164N, LEU212V, LEU322N, LEU329N, LEU33V, LEU373V, LEU374V, LEU384N, LEU384V, LEU389N, LEU389V, LEU405N, LEU405V, LEU418N, LEU438N, LEU444N, LEU453N, LEU536V, LEU538N, LEU539N, LEU539V, LEU551N, LEU552V, LEU553V, LEU554N, LEU559V, LEU560N, LEU560V, LEU576N, LEU67N, LEU67V, LEU79N, LYS108V, LYS163N, LYS167N, LYS190V, LYS229N, LYS248N, LYS272N, LYS30N, LYS313N, LYS324N, LYS346N, LYS346V, LYS347N, LYS347V, LYS348N, LYS348V, LYS413N, LYS413V, LYS528N, LYS528V, LYS541N, LYS563V, LYS574V, LYS582N, LYS583N, LYS66V, LYS83N, PHE187V, PHE209V, PHE222N, PHE309N, PHE336N, PHE350N, PHE351N, PHE351V, PHE359N, PHE359V, PHE35V, PHE432N, PHE449N, PHE524V, PHE557N, PHE557V, PHE57V, PRO137V, PRO148V, PRO204V, PRO210V, PRO302N, PRO345N, PRO345V, PRO349N, PRO349V, PRO353N, PRO370V, PRO385N, PRO385V, PRO388N, PRO388V, PRO395N, PRO395V, PRO398N, PRO398V, PRO543N, PRO547N, PRO587V, PRO62V, PRO75V, PRO82N, PRO88N, SER136V, SER13N, SER151V, SER154V, SER160N, SER162N, SER168N, SER178V, SER180V, SER22N, SER335V, SER36V, SER381N, SER39V, SER410N, SER523V, SER526V, SER69V, THR100V, THR106V, THR138V, THR20N, THR213V, THR216V, THR323N, THR344N, THR344V, THR377N, THR377V, THR386N, THR386V, THR409N, THR409V, THR417N, THR422N, THR434N, THR518N, THR542N, THR546N, THR558N, THR558V, TRP184V, TRP211V, TRP307N, TRP352N, TRP41V, TRP44V, TRP592V, TYR132V, TYR246N, TYR316N, TYR363N, TYR363V, TYR369V, TYR371V, TYR372V, TYR391N, TYR391V, TYR392N, TYR403N, TYR403V, TYR48V, TYR514N, TYR517N, TYR53V, TYR549V, TYR556V, TYR571V, TYR80N, VAL143V, VAL208V, VAL225N, VAL226N, VAL301N, VAL310N, VAL315N, VAL319N, VAL320N, VAL341V, VAL397N, VAL397V, VAL412N, VAL415N, VAL420N, VAL425N, VAL430N, VAL435N, VAL497N, VAL520N, VAL565V, VAL581N, VAL59V, VAL60V, VAL63N, VAL63V, VAL64V, VAL68V, VAL93N
• N-W: ALA86N, ARG343N, ASN366W, ASN394W, ASP339N, ASP367W, ASP368W, ASP84N, GLN399N, GLN52N, GLY85N, ILE340N, LYS347W, LYS563W, LYS83N, PRO345N, PRO370W, PRO88N, THR344N, TYR369W, TYR371W, TYR392N
• N-k: ALA126k, ARG125k, ARG343N, ARG54N, ASN138k, ASP339N, GLY137k, TYR128k, TYR53N
• N-l: ARG125l, ARG376N, ASN380N, ASP367N, ASP368N, ASP378N, ASP383N, GLU112l, GLU379N, HIS85l, LYS102l, LYS108l, THR377N
• N-m: ARG122m, ARG125m, ARG90m, ASP364N, ASP378N, GLU112m, GLU354N, GLU360N, GLU379N, GLU46m, HIS361N, LYS108m, LYS111m, LYS124m, LYS52m
• N-v: ARG131v, ARG54N, ASP325N, ASP339N, SER136v, TYR53N
• O-P: ALA107O, ALA110O, ALA17P, ALA195O, ALA21P, ALA338O, ALA342O, ALA342P, ALA357P, ALA390O, ALA390P, ALA400P, ALA402O, ALA402P, ALA407P, ALA408P, ALA411P, ALA416P, ALA424O, ALA431P, ALA442P, ALA572O, ALA86P, ALA90P, ALA91P, ARG103O, ARG116O, ARG145O, ARG146O, ARG14P, ARG171P, ARG269P, ARG26P, ARG273P, ARG274P, ARG27P, ARG321P, ARG328P, ARG330O, ARG330P, ARG343O, ARG343P, ARG376O, ARG37O, ARG441P, ARG511P, ARG513P, ARG532O, ARG532P, ARG54O, ARG569O, ARG569P, ARG61O, ARG65O, ARG72O, ARG81P, ARG87P, ARG99O, ASN105O, ASN112O, ASN141O, ASN161P, ASN182O, ASN203O, ASN205O, ASN31P, ASN331O, ASN337O, ASN337P, ASN366O, ASN366P, ASN375O, ASN380P, ASN394O, ASN394P, ASN401O, ASN401P, ASN426P, ASN436P, ASN439P, ASN452P, ASN531O, ASN531P, ASN573P, ASN6P, ASN74O, ASP131O, ASP134O, ASP159P, ASP166P, ASP169P, ASP16P, ASP186O, ASP196O, ASP206O, ASP215O, ASP23P, ASP312P, ASP325P, ASP339O, ASP339P, ASP364O, ASP364P, ASP367O, ASP368O, ASP378P, ASP383O, ASP383P, ASP421P, ASP42O, ASP433P, ASP43O, ASP443P, ASP519P, ASP561O, ASP570O, ASP58O, ASP84P, ASP89P, ASP92O, ASP92P, CYS516P, GLN135O, GLN142O, GLN181O, GLN214O, GLN218O, GLN270P, GLN327O, GLN327P, GLN355O, GLN355P, GLN387O, GLN387P, GLN399O, GLN399P, GLN40O, GLN429P, GLN437P, GLN525O, GLN529O, GLN530O, GLN530P, GLN544O, GLN550P, GLN555O, GLN555P, GLN56O, GLN575O, GLN591O, GLN73O, GLU117O, GLU120O, GLU133O, GLU147O, GLU185O, GLU189O, GLU227P, GLU230P, GLU24P, GLU28P, GLU296P, GLU306P, GLU311P, GLU314P, GLU317P, GLU354P, GLU360P, GLU379P, GLU393O, GLU393P, GLU396O, GLU396P, GLU406O, GLU414P, GLU423O, GLU423P, GLU445P, GLU495P, GLU515P, GLU534P, GLU537P, GLU548O, GLU548P, GLU566O, GLU588O, GLU595O, GLU5P, GLU70O, GLY183O, GLY305P, GLY308P, GLY318P, GLY326P, GLY358P, GLY365O, GLY365P, GLY382O, GLY382P, GLY419P, GLY427P, GLY428P, GLY512P, GLY545P, GLY55O, GLY562O, GLY564O, GLY580P, GLY85P, GLY96O, HIS104O, HIS150O, HIS155O, HIS172P, HIS177O, HIS361P, ILE109O, ILE113O, ILE119P, ILE149O, ILE176O, ILE217O, ILE271P, ILE333O, ILE333P, ILE340O, ILE340P, ILE356O, ILE356P, ILE510P, ILE535O, ILE535P, LEU164P, LEU212O, LEU322P, LEU329P, LEU33O, LEU373O, LEU374O, LEU384O, LEU384P, LEU389O, LEU389P, LEU405O, LEU405P, LEU418P, LEU438P, LEU444P, LEU453P, LEU536O, LEU538P, LEU539O, LEU539P, LEU551O, LEU551P, LEU552O, LEU553O, LEU554P, LEU559O, LEU559P, LEU560O, LEU560P, LEU576P, LEU67O, LEU67P, LEU79P, LYS108O, LYS163P, LYS167P, LYS190O, LYS229P, LYS248P, LYS272P, LYS30P, LYS313P, LYS324P, LYS346O, LYS346P, LYS347O, LYS347P, LYS348O, LYS348P, LYS413O, LYS413P, LYS528O, LYS528P, LYS541P, LYS563O, LYS574O, LYS582P, LYS583P, LYS66O, LYS83P, PHE187O, PHE209O, PHE222P, PHE309P, PHE336P, PHE350P, PHE351O, PHE351P, PHE359O, PHE359P, PHE35O, PHE432P, PHE449P, PHE524O, PHE557O, PHE557P, PHE57O, PRO137O, PRO148O, PRO204O, PRO210O, PRO302P, PRO345O, PRO345P, PRO349O, PRO349P, PRO353P, PRO370O, PRO385O, PRO385P, PRO388O, PRO388P, PRO395O, PRO395P, PRO398O, PRO398P, PRO543P, PRO547P, PRO587O, PRO62O, PRO75O, PRO82P, PRO88P, SER136O, SER13P, SER151O, SER154O, SER160P, SER162P, SER168P, SER178O, SER180O, SER22P, SER335O, SER36O, SER381P, SER39O, SER410P, SER523O, SER526O, SER69O, THR100O, THR106O, THR138O, THR20P, THR213O, THR216O, THR323P, THR344O, THR344P, THR377O, THR377P, THR386O, THR386P, THR409O, THR409P, THR417P, THR422P, THR434P, THR518P, THR542P, THR546P, THR558O, THR558P, TRP158P, TRP184O, TRP211O, TRP307P, TRP352P, TRP41O, TRP44O, TRP592O, TYR132O, TYR246P, TYR316P, TYR363O, TYR363P, TYR369O, TYR371O, TYR372O, TYR391O, TYR391P, TYR392P, TYR403O, TYR403P, TYR48O, TYR514P, TYR517P, TYR53O, TYR549O, TYR556O, TYR571O, TYR80P, VAL143O, VAL208O, VAL225P, VAL226P, VAL301P, VAL310P, VAL315P, VAL319P, VAL320P, VAL341O, VAL397O, VAL397P, VAL412P, VAL415P, VAL420P, VAL425P, VAL430P, VAL435P, VAL497P, VAL520P, VAL565O, VAL581P, VAL59O, VAL60O, VAL63O, VAL63P, VAL64O, VAL68O, VAL93P
• O-Q: ALA86Q, ARG343Q, ASN366O, ASN394O, ASP339Q, ASP367O, ASP368O, ASP84Q, GLN399Q, GLN52Q, GLY85Q, ILE340Q, LYS563O, LYS83Q, PRO345Q, PRO370O, PRO88Q, THR344Q, TYR369O, TYR371O, TYR392Q
• O-l: ALA126l, ARG125l, ARG343O, ARG54O, ASN138l, GLY137l, TYR128l, TYR53O
• O-m: ARG131m, ARG54O, ASP339O
• O-n: ARG122n, ARG125n, ARG90n, ASP364O, ASP378O, GLU112n, GLU354O, GLU360O, GLU379O, GLU46n, HIS361O, LYS108n, LYS111n, LYS124n, LYS52n
• O-o: ARG125o, ARG376O, ASN380O, ASP367O, ASP368O, ASP378O, ASP383O, GLU112o, GLU379O, HIS85o, LYS102o, LYS108o, THR377O
• P-Q: ALA107P, ALA110P, ALA17Q, ALA195P, ALA21Q, ALA338P, ALA342P, ALA342Q, ALA357Q, ALA390P, ALA390Q, ALA400Q, ALA402P, ALA402Q, ALA407Q, ALA408Q, ALA411Q, ALA416Q, ALA424P, ALA431Q, ALA442Q, ALA572P, ALA86Q, ALA90Q, ALA91Q, ARG103P, ARG116P, ARG145P, ARG146P, ARG14Q, ARG171Q, ARG269Q, ARG26Q, ARG273Q, ARG274Q, ARG27Q, ARG321Q, ARG328Q, ARG330P, ARG330Q, ARG343P, ARG343Q, ARG376P, ARG37P, ARG441Q, ARG511Q, ARG513Q, ARG532P, ARG532Q, ARG54P, ARG569P, ARG569Q, ARG61P, ARG65P, ARG72P, ARG81Q, ARG87Q, ARG99P, ASN105P, ASN112P, ASN141P, ASN161Q, ASN182P, ASN203P, ASN205P, ASN31Q, ASN337P, ASN337Q, ASN366P, ASN366Q, ASN375P, ASN380Q, ASN394P, ASN394Q, ASN401P, ASN401Q, ASN426Q, ASN436Q, ASN439Q, ASN452Q, ASN531P, ASN531Q, ASN573P, ASN573Q, ASN6Q, ASN74P, ASP131P, ASP134P, ASP159Q, ASP166Q, ASP169Q, ASP16Q, ASP186P, ASP196P, ASP206P, ASP215P, ASP23Q, ASP312Q, ASP325Q, ASP339P, ASP339Q, ASP364P, ASP364Q, ASP367P, ASP368P, ASP378Q, ASP383P, ASP383Q, ASP421Q, ASP42P, ASP433Q, ASP43P, ASP443Q, ASP519Q, ASP561P, ASP570P, ASP58P, ASP84Q, ASP89Q, ASP92P, ASP92Q, CYS516Q, GLN135P, GLN142P, GLN181P, GLN214P, GLN218P, GLN270Q, GLN327P, GLN327Q, GLN355P, GLN355Q, GLN387P, GLN387Q, GLN399P, GLN399Q, GLN40P, GLN429Q, GLN437Q, GLN525P, GLN529P, GLN530P, GLN530Q, GLN544P, GLN550Q, GLN555P, GLN555Q, GLN56P, GLN575P, GLN591P, GLN73P, GLU117P, GLU120P, GLU133P, GLU147P, GLU185P, GLU189P, GLU227Q, GLU230Q, GLU24Q, GLU28Q, GLU296Q, GLU306Q, GLU311Q, GLU314Q, GLU317Q, GLU354Q, GLU360Q, GLU379Q, GLU393P, GLU393Q, GLU396P, GLU396Q, GLU406P, GLU414Q, GLU423P, GLU423Q, GLU445Q, GLU495Q, GLU515Q, GLU534Q, GLU537Q, GLU548P, GLU548Q, GLU566P, GLU585Q, GLU588P, GLU595P, GLU5Q, GLU70P, GLY183P, GLY305Q, GLY308Q, GLY318Q, GLY326Q, GLY358Q, GLY365P, GLY365Q, GLY382P, GLY382Q, GLY419Q, GLY427Q, GLY428Q, GLY512Q, GLY545Q, GLY55P, GLY562P, GLY564P, GLY580Q, GLY85Q, GLY96P, HIS104P, HIS150P, HIS155P, HIS172Q, HIS177P, HIS361Q, ILE109P, ILE113P, ILE119Q, ILE149P, ILE176P, ILE217P, ILE271Q, ILE333P, ILE333Q, ILE340P, ILE340Q, ILE356P, ILE356Q, ILE510Q, ILE535P, ILE535Q, LEU164Q, LEU212P, LEU322Q, LEU329Q, LEU33P, LEU373P, LEU374P, LEU384P, LEU384Q, LEU389P, LEU389Q, LEU405P, LEU405Q, LEU418Q, LEU438Q, LEU444Q, LEU453Q, LEU536P, LEU538Q, LEU539P, LEU539Q, LEU551Q, LEU552P, LEU553P, LEU554Q, LEU559P, LEU560P, LEU560Q, LEU576Q, LEU67P, LEU67Q, LEU79Q, LYS108P, LYS163Q, LYS167Q, LYS190P, LYS229Q, LYS248Q, LYS272Q, LYS30Q, LYS313Q, LYS324Q, LYS346P, LYS346Q, LYS347P, LYS347Q, LYS348P, LYS348Q, LYS413P, LYS413Q, LYS528P, LYS528Q, LYS541Q, LYS563P, LYS574P, LYS582Q, LYS583Q, LYS66P, LYS83Q, PHE187P, PHE209P, PHE222Q, PHE309Q, PHE336Q, PHE350Q, PHE351P, PHE351Q, PHE359P, PHE359Q, PHE35P, PHE432Q, PHE449Q, PHE524P, PHE557P, PHE557Q, PHE57P, PRO137P, PRO148P, PRO204P, PRO210P, PRO302Q, PRO345P, PRO345Q, PRO349P, PRO349Q, PRO353Q, PRO370P, PRO385P, PRO385Q, PRO388P, PRO388Q, PRO395P, PRO395Q, PRO398P, PRO398Q, PRO543Q, PRO547Q, PRO587P, PRO62P, PRO75P, PRO82Q, PRO88Q, SER136P, SER13Q, SER151P, SER154P, SER160Q, SER162Q, SER168Q, SER178P, SER180P, SER22Q, SER335P, SER36P, SER381Q, SER39P, SER410Q, SER523P, SER526P, SER69P, THR100P, THR106P, THR138P, THR20Q, THR213P, THR216P, THR323Q, THR344P, THR344Q, THR377P, THR377Q, THR386P, THR386Q, THR409P, THR409Q, THR417Q, THR422Q, THR434Q, THR518Q, THR542Q, THR546Q, THR558P, THR558Q, TRP184P, TRP211P, TRP307Q, TRP352Q, TRP41P, TRP44P, TRP592P, TYR132P, TYR246Q, TYR316Q, TYR363P, TYR363Q, TYR369P, TYR371P, TYR372P, TYR391P, TYR391Q, TYR392Q, TYR403P, TYR403Q, TYR48P, TYR514Q, TYR517Q, TYR53P, TYR549P, TYR556P, TYR571P, TYR80Q, VAL143P, VAL208P, VAL225Q, VAL226Q, VAL301Q, VAL310Q, VAL315Q, VAL319Q, VAL320Q, VAL341P, VAL397P, VAL397Q, VAL412Q, VAL415Q, VAL420Q, VAL425Q, VAL430Q, VAL435Q, VAL497Q, VAL520Q, VAL565P, VAL581Q, VAL59P, VAL60P, VAL63P, VAL63Q, VAL64P, VAL68P, VAL93Q
• P-R: ALA86R, ARG343R, ASN366P, ASN394P, ASP339R, ASP367P, ASP368P, ASP84R, GLN399R, GLN52R, GLY85R, ILE340R, LYS563P, LYS83R, PRO345R, PRO370P, PRO88R, THR344R, TYR369P, TYR371P, TYR392R
• P-l: ARG131l, ARG54P, ASP325P, ASP339P, GLN52P, SER130l, SER136l
• P-n: ALA126n, ARG125n, ARG343P, ARG54P, ASN138n, GLN52P, GLY137n, TYR128n, TYR53P
• P-o: ARG122o, ARG125o, ARG90o, ASP364P, ASP378P, GLU112o, GLU354P, GLU360P, GLU379P, GLU46o, HIS361P, LYS108o, LYS111o, LYS124o, LYS52o
• P-p: ARG125p, ARG376P, ASN380P, ASP367P, ASP368P, ASP378P, ASP383P, GLU112p, GLU379P, HIS85p, LYS102p, LYS108p, THR377P
• Q-R: ALA107Q, ALA110Q, ALA17R, ALA195Q, ALA21R, ALA338Q, ALA342Q, ALA342R, ALA357R, ALA390Q, ALA390R, ALA400R, ALA402Q, ALA402R, ALA407R, ALA408R, ALA411R, ALA416R, ALA424Q, ALA431R, ALA442R, ALA572Q, ALA86R, ALA90R, ALA91R, ARG103Q, ARG116Q, ARG145Q, ARG146Q, ARG14R, ARG171R, ARG269R, ARG26R, ARG273R, ARG274R, ARG275R, ARG27R, ARG321R, ARG328R, ARG330Q, ARG330R, ARG343Q, ARG343R, ARG376Q, ARG37Q, ARG441R, ARG511R, ARG513R, ARG532Q, ARG532R, ARG54Q, ARG569Q, ARG569R, ARG61Q, ARG65Q, ARG72Q, ARG81R, ARG87R, ARG99Q, ASN105Q, ASN112Q, ASN141Q, ASN161R, ASN182Q, ASN203Q, ASN205Q, ASN31R, ASN337Q, ASN337R, ASN366Q, ASN366R, ASN375Q, ASN380R, ASN394Q, ASN394R, ASN401Q, ASN401R, ASN426R, ASN436R, ASN439R, ASN452R, ASN531Q, ASN531R, ASN573Q, ASN573R, ASN6R, ASN74Q, ASP131Q, ASP134Q, ASP159R, ASP166R, ASP169R, ASP16R, ASP186Q, ASP196Q, ASP206Q, ASP215Q, ASP23R, ASP312R, ASP325R, ASP339Q, ASP339R, ASP364Q, ASP364R, ASP367Q, ASP368Q, ASP378R, ASP383Q, ASP383R, ASP421R, ASP42Q, ASP433R, ASP43Q, ASP443R, ASP519R, ASP561Q, ASP570Q, ASP58Q, ASP84R, ASP89R, ASP92Q, ASP92R, CYS516R, GLN135Q, GLN142Q, GLN181Q, GLN214Q, GLN218Q, GLN270R, GLN327Q, GLN327R, GLN355Q, GLN355R, GLN387Q, GLN387R, GLN399Q, GLN399R, GLN40Q, GLN429R, GLN437R, GLN525Q, GLN529Q, GLN530Q, GLN530R, GLN544Q, GLN550R, GLN555Q, GLN555R, GLN56Q, GLN575Q, GLN591Q, GLN73Q, GLU117Q, GLU120Q, GLU133Q, GLU147Q, GLU185Q, GLU189Q, GLU227R, GLU230R, GLU24R, GLU28R, GLU296R, GLU306R, GLU311R, GLU314R, GLU317R, GLU354R, GLU360R, GLU379R, GLU393Q, GLU393R, GLU396Q, GLU396R, GLU406Q, GLU414R, GLU423Q, GLU445R, GLU462R, GLU495R, GLU515R, GLU534R, GLU537R, GLU548Q, GLU548R, GLU566Q, GLU585R, GLU588Q, GLU595Q, GLU5R, GLU70Q, GLY183Q, GLY305R, GLY308R, GLY318R, GLY326R, GLY358R, GLY365Q, GLY365R, GLY382Q, GLY382R, GLY419R, GLY427R, GLY428R, GLY512R, GLY545R, GLY55Q, GLY562Q, GLY564Q, GLY580R, GLY85R, GLY96Q, HIS104Q, HIS150Q, HIS155Q, HIS172R, HIS177Q, HIS361R, ILE109Q, ILE113Q, ILE119R, ILE149Q, ILE176Q, ILE271R, ILE333Q, ILE333R, ILE340Q, ILE340R, ILE356Q, ILE356R, ILE510R, ILE535Q, ILE535R, LEU164R, LEU212Q, LEU322R, LEU329R, LEU33Q, LEU373Q, LEU374Q, LEU384Q, LEU384R, LEU389Q, LEU389R, LEU405Q, LEU405R, LEU418R, LEU438R, LEU444R, LEU453R, LEU536Q, LEU538R, LEU539Q, LEU539R, LEU551R, LEU552Q, LEU553Q, LEU554R, LEU559Q, LEU560Q, LEU560R, LEU576R, LEU67Q, LEU67R, LEU79R, LYS108Q, LYS163R, LYS167R, LYS190Q, LYS229R, LYS248R, LYS272R, LYS30R, LYS313R, LYS324R, LYS346Q, LYS346R, LYS347Q, LYS347R, LYS348Q, LYS348R, LYS413Q, LYS413R, LYS528Q, LYS528R, LYS541R, LYS563Q, LYS574Q, LYS582R, LYS583R, LYS66Q, LYS83R, PHE187Q, PHE209Q, PHE222R, PHE309R, PHE336R, PHE34Q, PHE350R, PHE351Q, PHE351R, PHE359Q, PHE359R, PHE35Q, PHE432R, PHE449R, PHE524Q, PHE557Q, PHE557R, PHE57Q, PRO137Q, PRO148Q, PRO204Q, PRO210Q, PRO302R, PRO345Q, PRO345R, PRO349Q, PRO349R, PRO353R, PRO370Q, PRO385Q, PRO385R, PRO388Q, PRO388R, PRO395Q, PRO395R, PRO398Q, PRO398R, PRO543R, PRO547R, PRO587Q, PRO62Q, PRO75Q, PRO82R, PRO88R, SER136Q, SER13R, SER151Q, SER154Q, SER160R, SER162R, SER168R, SER178Q, SER180Q, SER22R, SER335Q, SER36Q, SER381R, SER39Q, SER410R, SER523Q, SER526Q, SER69Q, THR100Q, THR106Q, THR138Q, THR20R, THR213Q, THR216Q, THR323R, THR344Q, THR344R, THR377Q, THR377R, THR386Q, THR386R, THR409Q, THR409R, THR417R, THR422R, THR434R, THR446R, THR518R, THR542R, THR546R, THR558Q, THR558R, TRP184Q, TRP211Q, TRP307R, TRP352R, TRP41Q, TRP44Q, TRP592Q, TYR132Q, TYR246R, TYR316R, TYR363Q, TYR363R, TYR369Q, TYR371Q, TYR372Q, TYR391Q, TYR391R, TYR392R, TYR403Q, TYR403R, TYR48Q, TYR514R, TYR517R, TYR53Q, TYR549Q, TYR556Q, TYR571Q, TYR80R, VAL143Q, VAL208Q, VAL225R, VAL226R, VAL301R, VAL310R, VAL315R, VAL319R, VAL320R, VAL341Q, VAL397Q, VAL397R, VAL412R, VAL415R, VAL420R, VAL425R, VAL430R, VAL435R, VAL497R, VAL520R, VAL565Q, VAL581R, VAL59Q, VAL60Q, VAL63Q, VAL63R, VAL64Q, VAL68Q, VAL93R
• Q-X: ALA86X, ARG343X, ASN366Q, ASP339X, ASP367Q, ASP368Q, ASP84X, GLN52X, GLY85X, LYS563Q, LYS83X, PRO88X
• Q-n: ARG131n, ARG54Q, ASP325Q, ASP339Q, GLN52Q, SER130n, SER136n, TYR53Q
• Q-o: ALA126o, ARG125o, ARG343Q, ARG54Q, ASN138o, GLY137o, TYR128o, TYR53Q
• Q-p: ARG122p, ARG125p, ARG90p, ASP364Q, ASP378Q, GLU112p, GLU354Q, GLU360Q, GLU379Q, GLU46p, HIS361Q, LYS108p, LYS111p, LYS124p, LYS52p
• Q-r: ARG125-3.7496963.218826, ARG125r, ARG376Q, ASN380Q, ASP367Q, ASP368Q, ASP378Q, ASP383Q, GLU112-6.9030293.115915, GLU112-7.9612662.950319, GLU112r, GLU379Q, HIS85r, LYS102-10.8914942.766536, LYS102-11.5390592.714637, LYS102r, LYS108r, THR377Q
• R-U: ALA86U, ARG343U, ASN366R, ASN394R, ASP339U, ASP367R, ASP368R, ASP84U, GLN399U, GLN52U, GLY85U, ILE340U, LYS563R, LYS83U, PRO345U, PRO370R, PRO88U, THR344U, TYR369R, TYR371R, TYR392U
• R-X: ALA107R, ALA110R, ALA17X, ALA195R, ALA21X, ALA400X, ALA86X, ALA90X, ALA91X, ARG103R, ARG116R, ARG145R, ARG146R, ARG14X, ARG171X, ARG269X, ARG26X, ARG273X, ARG274X, ARG27X, ARG321X, ARG343X, ARG376R, ARG37R, ARG441X, ARG511X, ARG532R, ARG532X, ARG569R, ARG61R, ARG65R, ARG81X, ARG87X, ARG99R, ASN105R, ASN141R, ASN161X, ASN182R, ASN31X, ASN394R, ASN531R, ASN573R, ASN6X, ASP131R, ASP134R, ASP159X, ASP166X, ASP169X, ASP16X, ASP186R, ASP196R, ASP206R, ASP215R, ASP23X, ASP312X, ASP325X, ASP339X, ASP364R, ASP367R, ASP378X, ASP383X, ASP421X, ASP519X, ASP561R, ASP570R, ASP58R, ASP84X, ASP89X, ASP92R, ASP92X, GLN135R, GLN142R, GLN181R, GLN214R, GLN270X, GLN399X, GLN40R, GLN525R, GLN529R, GLN530R, GLU133R, GLU147R, GLU185R, GLU189R, GLU227X, GLU230X, GLU24X, GLU28X, GLU306X, GLU311X, GLU314X, GLU317X, GLU354X, GLU393X, GLU396R, GLU396X, GLU414X, GLU423R, GLU445X, GLU566R, GLU5X, GLU70R, GLY183R, GLY562R, GLY85X, GLY96R, HIS104R, HIS150R, HIS155R, HIS172X, HIS177R, ILE109R, ILE113R, ILE119X, ILE149R, ILE217R, ILE271X, LEU164X, LEU212R, LEU374R, LEU438X, LEU559R, LEU560R, LEU67X, LEU79X, LYS108R, LYS163X, LYS167X, LYS190R, LYS229X, LYS248X, LYS272X, LYS30X, LYS346R, LYS346X, LYS347R, LYS348X, LYS413R, LYS528R, LYS528X, LYS563R, LYS583X, LYS66R, LYS83X, PHE187R, PHE209R, PHE222X, PHE351X, PHE557R, PRO137R, PRO148R, PRO210R, PRO349X, PRO395R, PRO82X, PRO88X, SER136R, SER13X, SER160X, SER162X, SER168X, SER178R, SER180R, SER22X, SER526R, THR100R, THR106R, THR138R, THR20X, THR213R, THR434X, THR558R, TRP184R, TRP211R, TRP41R, TYR132R, TYR246X, TYR372R, TYR48R, TYR80X, VAL143R, VAL208R, VAL225X, VAL226X, VAL565R, VAL63X, VAL93X
• R-o: ARG131o, ARG54R, ASP325R, ASP339R, SER136o, TYR53R
• R-p: ALA126p, ARG125p, ARG343R, ARG54R, ASN138p, GLY137p, TYR128p, TYR53R
• R-q: ARG125q, ARG376R, ASN380R, ASP367R, ASP368R, ASP378R, ASP383R, GLU112q, GLU379R, HIS85q, LYS102q, LYS108q, THR377R
• R-r: ARG122r, ARG125r, ARG90-3.6138912.945175, ARG90r, ASP364R, ASP378R, GLU112r, GLU354R, GLU360R, GLU379R, GLU46r, HIS361R, LYS108r, LYS111r, LYS124r, LYS52r
• S-T: ALA107S, ALA110S, ALA17T, ALA195S, ALA21T, ALA338S, ALA342S, ALA342T, ALA357T, ALA390S, ALA390T, ALA400T, ALA402S, ALA402T, ALA407T, ALA408T, ALA411T, ALA416T, ALA424S, ALA431T, ALA442T, ALA572S, ALA86T, ALA90T, ALA91T, ARG103S, ARG116S, ARG145S, ARG146S, ARG14T, ARG171T, ARG269T, ARG26T, ARG273T, ARG274T, ARG27T, ARG321T, ARG328T, ARG330S, ARG330T, ARG343S, ARG343T, ARG376S, ARG37S, ARG441T, ARG511T, ARG513T, ARG532S, ARG532T, ARG54S, ARG569S, ARG569T, ARG61S, ARG65S, ARG72S, ARG81T, ARG87T, ARG99S, ASN105S, ASN112S, ASN141S, ASN161T, ASN182S, ASN203S, ASN205S, ASN31T, ASN337S, ASN337T, ASN366S, ASN375S, ASN380T, ASN394S, ASN394T, ASN401S, ASN401T, ASN426T, ASN436T, ASN439T, ASN452T, ASN531S, ASN531T, ASN573T, ASN6T, ASN74S, ASP131S, ASP134S, ASP159T, ASP166T, ASP169T, ASP16T, ASP186S, ASP196S, ASP206S, ASP215S, ASP23T, ASP312T, ASP325T, ASP339S, ASP339T, ASP364S, ASP364T, ASP367S, ASP368S, ASP378T, ASP383S, ASP383T, ASP421T, ASP42S, ASP433T, ASP43S, ASP443T, ASP519T, ASP561S, ASP570S, ASP58S, ASP84T, ASP89T, ASP92S, ASP92T, CYS516T, GLN135S, GLN142S, GLN181S, GLN214S, GLN218S, GLN270T, GLN327S, GLN327T, GLN355S, GLN355T, GLN387S, GLN387T, GLN399S, GLN399T, GLN40S, GLN429T, GLN437T, GLN525S, GLN529S, GLN530S, GLN530T, GLN544S, GLN550T, GLN555S, GLN555T, GLN56S, GLN575S, GLN591S, GLN73S, GLU117S, GLU120S, GLU133S, GLU147S, GLU185S, GLU189S, GLU224T, GLU227T, GLU230T, GLU24T, GLU28T, GLU296T, GLU306T, GLU311T, GLU314T, GLU317T, GLU354T, GLU360T, GLU379T, GLU393S, GLU393T, GLU396S, GLU396T, GLU406S, GLU414T, GLU423S, GLU445T, GLU495T, GLU515T, GLU534T, GLU537T, GLU548S, GLU548T, GLU566S, GLU585T, GLU588S, GLU595S, GLU5T, GLU70S, GLY183S, GLY305T, GLY308T, GLY318T, GLY326T, GLY358T, GLY365S, GLY365T, GLY382S, GLY382T, GLY419T, GLY427T, GLY428T, GLY512T, GLY545T, GLY55S, GLY562S, GLY564S, GLY580T, GLY85T, GLY96S, HIS104S, HIS150S, HIS155S, HIS172T, HIS177S, HIS361T, ILE109S, ILE113S, ILE119T, ILE149S, ILE176S, ILE217S, ILE271T, ILE333S, ILE333T, ILE340S, ILE340T, ILE356S, ILE356T, ILE510T, ILE535S, ILE535T, LEU164T, LEU212S, LEU322T, LEU329T, LEU33S, LEU373S, LEU374S, LEU384S, LEU384T, LEU389S, LEU389T, LEU405S, LEU405T, LEU418T, LEU438T, LEU444T, LEU453T, LEU536S, LEU538T, LEU539S, LEU539T, LEU551T, LEU552S, LEU553S, LEU554T, LEU559S, LEU559T, LEU560S, LEU560T, LEU576T, LEU67S, LEU67T, LEU79T, LYS108S, LYS163T, LYS167T, LYS190S, LYS229T, LYS248T, LYS272T, LYS30T, LYS313T, LYS324T, LYS346S, LYS346T, LYS347S, LYS347T, LYS348S, LYS348T, LYS413S, LYS413T, LYS528S, LYS528T, LYS541T, LYS563S, LYS574S, LYS582T, LYS583T, LYS66S, LYS83T, PHE187S, PHE209S, PHE222T, PHE309T, PHE336T, PHE34S, PHE350T, PHE351S, PHE351T, PHE359S, PHE359T, PHE35S, PHE432T, PHE449T, PHE524S, PHE557S, PHE557T, PHE57S, PRO137S, PRO148S, PRO204S, PRO210S, PRO302T, PRO345S, PRO345T, PRO349S, PRO349T, PRO353T, PRO370S, PRO385S, PRO385T, PRO388S, PRO388T, PRO395S, PRO395T, PRO398S, PRO398T, PRO543T, PRO547T, PRO587S, PRO62S, PRO75S, PRO82T, PRO88T, SER136S, SER13T, SER151S, SER154S, SER160T, SER162T, SER168T, SER178S, SER180S, SER22T, SER335S, SER36S, SER381T, SER39S, SER410T, SER523S, SER526S, SER69S, THR100S, THR106S, THR138S, THR20T, THR213S, THR216S, THR323T, THR344S, THR344T, THR377S, THR377T, THR386S, THR386T, THR409S, THR409T, THR417T, THR422T, THR434T, THR518T, THR542T, THR546T, THR558S, THR558T, TRP184S, TRP211S, TRP307T, TRP352T, TRP41S, TRP44S, TRP592S, TYR132S, TYR246T, TYR316T, TYR363S, TYR363T, TYR369S, TYR371S, TYR372S, TYR391S, TYR391T, TYR392T, TYR403S, TYR403T, TYR48S, TYR514T, TYR517T, TYR53S, TYR549S, TYR556S, TYR571S, TYR80T, VAL143S, VAL208S, VAL225T, VAL226T, VAL301T, VAL310T, VAL315T, VAL319T, VAL320T, VAL341S, VAL397S, VAL397T, VAL412T, VAL415T, VAL420T, VAL425T, VAL430T, VAL435T, VAL497T, VAL520T, VAL565S, VAL581T, VAL59S, VAL60S, VAL63S, VAL63T, VAL64S, VAL68S, VAL93T
• S-U: ALA107U, ALA110U, ALA17S, ALA195U, ALA21S, ALA338U, ALA342S, ALA342U, ALA357S, ALA390S, ALA390U, ALA400S, ALA402S, ALA402U, ALA407S, ALA408S, ALA411S, ALA416S, ALA424U, ALA431S, ALA442S, ALA572U, ALA86S, ALA90S, ALA91S, ARG103U, ARG116U, ARG145U, ARG146U, ARG14S, ARG171S, ARG269S, ARG26S, ARG273S, ARG274S, ARG27S, ARG321S, ARG328S, ARG330S, ARG330U, ARG343S, ARG343U, ARG376U, ARG37U, ARG441S, ARG511S, ARG513S, ARG532S, ARG532U, ARG54U, ARG569S, ARG569U, ARG61U, ARG65U, ARG72U, ARG81S, ARG87S, ARG99U, ASN105U, ASN112U, ASN141U, ASN161S, ASN182U, ASN203U, ASN205U, ASN31S, ASN337S, ASN337U, ASN366S, ASN366U, ASN375U, ASN380S, ASN394S, ASN394U, ASN401S, ASN401U, ASN426S, ASN436S, ASN439S, ASN452S, ASN531S, ASN531U, ASN573S, ASN6S, ASN74U, ASP131U, ASP134U, ASP159S, ASP166S, ASP169S, ASP16S, ASP186U, ASP196U, ASP206U, ASP215U, ASP23S, ASP312S, ASP325S, ASP339S, ASP339U, ASP364S, ASP364U, ASP367U, ASP368U, ASP378S, ASP383S, ASP383U, ASP421S, ASP42U, ASP433S, ASP43U, ASP443S, ASP519S, ASP561U, ASP570U, ASP58U, ASP84S, ASP89S, ASP92S, ASP92U, CYS516S, GLN135U, GLN181U, GLN214U, GLN218U, GLN270S, GLN327S, GLN327U, GLN355S, GLN355U, GLN387S, GLN387U, GLN399S, GLN399U, GLN40U, GLN429S, GLN437S, GLN525U, GLN529U, GLN530S, GLN530U, GLN544U, GLN550S, GLN555S, GLN555U, GLN56U, GLN575U, GLN591U, GLN73U, GLU117U, GLU120U, GLU133U, GLU147U, GLU185U, GLU189U, GLU227S, GLU230S, GLU24S, GLU28S, GLU296S, GLU306S, GLU311S, GLU314S, GLU317S, GLU354S, GLU360S, GLU379S, GLU393S, GLU393U, GLU396S, GLU396U, GLU406U, GLU414S, GLU423U, GLU445S, GLU495S, GLU515S, GLU534S, GLU537S, GLU548S, GLU548U, GLU566U, GLU585S, GLU588U, GLU5S, GLU70U, GLY183U, GLY305S, GLY308S, GLY318S, GLY326S, GLY358S, GLY365S, GLY365U, GLY382S, GLY382U, GLY419S, GLY427S, GLY428S, GLY512S, GLY545S, GLY55U, GLY562U, GLY564U, GLY580S, GLY85S, GLY96U, HIS104U, HIS150U, HIS155U, HIS172S, HIS177U, HIS361S, ILE109U, ILE113U, ILE119S, ILE149U, ILE176U, ILE217U, ILE271S, ILE333S, ILE333U, ILE340S, ILE340U, ILE356S, ILE356U, ILE510S, ILE535S, ILE535U, LEU164S, LEU212U, LEU322S, LEU329S, LEU33U, LEU373U, LEU374U, LEU384S, LEU384U, LEU389S, LEU389U, LEU405S, LEU405U, LEU418S, LEU438S, LEU444S, LEU453S, LEU536U, LEU538S, LEU539S, LEU539U, LEU551S, LEU552U, LEU553U, LEU554S, LEU559U, LEU560S, LEU560U, LEU576S, LEU67S, LEU67U, LEU79S, LYS108U, LYS163S, LYS167S, LYS190U, LYS229S, LYS248S, LYS272S, LYS30S, LYS313S, LYS324S, LYS346S, LYS346U, LYS347S, LYS347U, LYS348S, LYS348U, LYS413S, LYS413U, LYS528S, LYS528U, LYS541S, LYS563U, LYS574U, LYS582S, LYS583S, LYS66U, LYS83S, PHE187U, PHE209U, PHE222S, PHE309S, PHE336S, PHE350S, PHE351S, PHE351U, PHE359S, PHE359U, PHE35U, PHE432S, PHE449S, PHE524U, PHE557S, PHE557U, PHE57U, PRO137U, PRO148U, PRO204U, PRO210U, PRO302S, PRO345S, PRO345U, PRO349S, PRO349U, PRO353S, PRO370U, PRO385S, PRO385U, PRO388S, PRO388U, PRO395S, PRO395U, PRO398S, PRO398U, PRO543S, PRO547S, PRO587U, PRO62U, PRO75U, PRO82S, PRO88S, SER136U, SER13S, SER151U, SER154U, SER160S, SER162S, SER168S, SER178U, SER180U, SER22S, SER335U, SER36U, SER381S, SER39U, SER410S, SER523U, SER526U, SER69U, THR100U, THR106U, THR138U, THR20S, THR213U, THR216U, THR323S, THR344S, THR344U, THR377S, THR377U, THR386S, THR386U, THR409S, THR409U, THR417S, THR422S, THR434S, THR518S, THR542S, THR546S, THR558S, THR558U, TRP184U, TRP211U, TRP307S, TRP352S, TRP41U, TRP44U, TRP592U, TYR132U, TYR246S, TYR316S, TYR363S, TYR363U, TYR369U, TYR371U, TYR372U, TYR391S, TYR391U, TYR392S, TYR403S, TYR403U, TYR48U, TYR514S, TYR517S, TYR53U, TYR549U, TYR556U, TYR571U, TYR80S, VAL143U, VAL208U, VAL225S, VAL226S, VAL301S, VAL310S, VAL315S, VAL319S, VAL320S, VAL341U, VAL397S, VAL397U, VAL412S, VAL415S, VAL420S, VAL425S, VAL430S, VAL435S, VAL497S, VAL520S, VAL565U, VAL581S, VAL59U, VAL60U, VAL63S, VAL63U, VAL64U, VAL68U, VAL93S
• S-W: ALA86W, ARG343W, ASN366S, ASN394S, ASP339W, ASP367S, ASP368S, ASP84W, GLN399W, GLN52W, GLY85W, ILE340W, LYS563S, LYS83W, PRO345W, PRO370S, PRO88W, THR344W, TYR369S, TYR371S, TYR392W
• S-X: ARG343S, ASP339S, ASP367X
• S-q: ARG131q, ARG54S, ASP325S, ASP339S, SER136q, TYR53S
• S-s: ALA126s, ARG122s, ARG125s, ARG90s, ASP364S, ASP378S, GLU112s, GLU354S, GLU360S, GLU379S, GLU46s, HIS361S, LYS108s, LYS111s, LYS124s, LYS52s, TYR115s
• S-t: ALA126t, ARG125t, ARG343S, ARG54S, ASN138t, ASP339S, GLY137t, TYR128t, TYR53S
• S-u: ARG125u, ARG376S, ASN380S, ASP367S, ASP368S, ASP378S, ASP383S, GLU112u, GLU379S, HIS85u, LYS102u, LYS108u, THR377S
• T-U: ALA86T, ARG343T, ASN366U, ASN394U, ASP339T, ASP367U, ASP368U, ASP84T, GLN399T, GLN52T, GLY85T, ILE340T, LYS563U, PRO345T, PRO370U, PRO88T, THR344T, TYR369U, TYR371U, TYR392T
• T-V: ALA86V, ARG343V, ASN366T, ASN394T, ASP339V, ASP367T, ASP368T, ASP84V, GLN399V, GLN52V, GLY85V, ILE340V, LYS347T, LYS563T, LYS83V, PRO345V, PRO370T, PRO88V, THR344V, TYR369T, TYR371T, TYR392V
• T-W: ALA107T, ALA110T, ALA17W, ALA195T, ALA21W, ALA338T, ALA342T, ALA342W, ALA357W, ALA390T, ALA390W, ALA400T, ALA400W, ALA402T, ALA402W, ALA407W, ALA408W, ALA411W, ALA416W, ALA424T, ALA431W, ALA442W, ALA572T, ALA86W, ALA90W, ALA91W, ARG103T, ARG116T, ARG145T, ARG146T, ARG14W, ARG171W, ARG269W, ARG26W, ARG273W, ARG274W, ARG27W, ARG321W, ARG328W, ARG330T, ARG330W, ARG343T, ARG343W, ARG376T, ARG37T, ARG441W, ARG511W, ARG513W, ARG532T, ARG532W, ARG54T, ARG569T, ARG569W, ARG61T, ARG65T, ARG72T, ARG81W, ARG87W, ARG99T, ASN105T, ASN112T, ASN141T, ASN161W, ASN182T, ASN203T, ASN205T, ASN31W, ASN337T, ASN337W, ASN366T, ASN375T, ASN380W, ASN394T, ASN394W, ASN401T, ASN401W, ASN426W, ASN436W, ASN439W, ASN452W, ASN531T, ASN531W, ASN573T, ASN573W, ASN6W, ASN74T, ASP131T, ASP134T, ASP159W, ASP166W, ASP169W, ASP16W, ASP186T, ASP196T, ASP206T, ASP215T, ASP23W, ASP312W, ASP325W, ASP339T, ASP339W, ASP364T, ASP364W, ASP367T, ASP368T, ASP378W, ASP383T, ASP383W, ASP421W, ASP42T, ASP433W, ASP43T, ASP443W, ASP519W, ASP561T, ASP570T, ASP58T, ASP84W, ASP89W, ASP92T, ASP92W, CYS516W, GLN135T, GLN142T, GLN181T, GLN214T, GLN218T, GLN270W, GLN327T, GLN327W, GLN355T, GLN355W, GLN387T, GLN387W, GLN399T, GLN399W, GLN40T, GLN429W, GLN437W, GLN525T, GLN529T, GLN530T, GLN530W, GLN544T, GLN550W, GLN555T, GLN555W, GLN56T, GLN575T, GLN591T, GLN73T, GLU117T, GLU120T, GLU133T, GLU147T, GLU185T, GLU189T, GLU227W, GLU230W, GLU24W, GLU28W, GLU296W, GLU306W, GLU311W, GLU314W, GLU317W, GLU354W, GLU360W, GLU379W, GLU393T, GLU393W, GLU396T, GLU396W, GLU406T, GLU414W, GLU423T, GLU423W, GLU445W, GLU495W, GLU515W, GLU534W, GLU537W, GLU548T, GLU548W, GLU566T, GLU585W, GLU588T, GLU595T, GLU5W, GLU70T, GLY183T, GLY305W, GLY308W, GLY318W, GLY326W, GLY365T, GLY365W, GLY382T, GLY382W, GLY419W, GLY427W, GLY428W, GLY512W, GLY545W, GLY55T, GLY562T, GLY564T, GLY580W, GLY85W, GLY96T, HIS104T, HIS150T, HIS155T, HIS172W, HIS177T, HIS361W, ILE109T, ILE113T, ILE119W, ILE149T, ILE176T, ILE217T, ILE271W, ILE333T, ILE333W, ILE340T, ILE340W, ILE356T, ILE356W, ILE510W, ILE535T, ILE535W, LEU164W, LEU212T, LEU322W, LEU329W, LEU33T, LEU373T, LEU374T, LEU384T, LEU384W, LEU389T, LEU389W, LEU405T, LEU405W, LEU418W, LEU438W, LEU444W, LEU453W, LEU536T, LEU538W, LEU539T, LEU539W, LEU551W, LEU552T, LEU553T, LEU554W, LEU559T, LEU560T, LEU560W, LEU576W, LEU67T, LEU67W, LEU79W, LYS108T, LYS163W, LYS167W, LYS190T, LYS229W, LYS248W, LYS272W, LYS30W, LYS313W, LYS324W, LYS346T, LYS346W, LYS347T, LYS347W, LYS348T, LYS348W, LYS413T, LYS413W, LYS528T, LYS528W, LYS541W, LYS563T, LYS574T, LYS582W, LYS583W, LYS66T, LYS83W, PHE187T, PHE209T, PHE222W, PHE309W, PHE336W, PHE350W, PHE351T, PHE351W, PHE359T, PHE359W, PHE35T, PHE432W, PHE449W, PHE524T, PHE557T, PHE557W, PHE57T, PRO137T, PRO148T, PRO204T, PRO210T, PRO302W, PRO345T, PRO345W, PRO349T, PRO349W, PRO353W, PRO370T, PRO385T, PRO385W, PRO388T, PRO388W, PRO395T, PRO395W, PRO398T, PRO398W, PRO543W, PRO547W, PRO587T, PRO62T, PRO75T, PRO82W, PRO88W, SER136T, SER13W, SER151T, SER154T, SER160W, SER162W, SER168W, SER178T, SER180T, SER22W, SER335T, SER36T, SER381W, SER39T, SER410W, SER523T, SER526T, SER69T, THR100T, THR106T, THR138T, THR20W, THR213T, THR216T, THR323W, THR344T, THR344W, THR377T, THR377W, THR386T, THR386W, THR409T, THR409W, THR417W, THR422W, THR434W, THR518W, THR542W, THR546W, THR558T, THR558W, TRP184T, TRP211T, TRP307W, TRP352W, TRP41T, TRP44T, TRP592T, TYR132T, TYR246W, TYR316W, TYR363T, TYR363W, TYR369T, TYR371T, TYR372T, TYR391T, TYR391W, TYR392W, TYR403T, TYR403W, TYR48T, TYR514W, TYR517W, TYR53T, TYR549T, TYR556T, TYR571T, TYR80W, VAL143T, VAL208T, VAL225W, VAL226W, VAL301W, VAL310W, VAL315W, VAL319W, VAL320W, VAL341T, VAL397T, VAL397W, VAL412W, VAL415W, VAL420W, VAL425W, VAL430W, VAL435W, VAL497W, VAL520W, VAL565T, VAL581W, VAL59T, VAL60T, VAL63T, VAL63W, VAL64T, VAL68T, VAL93W
• T-s: ALA126s, ARG125s, ARG343T, ARG54T, ASN138s, ASP339T, GLY137s, TYR128s, TYR53T
• T-t: ARG131t, ARG54T, ASP325T, ASP339T, SER136t, TYR53T
• T-u: ARG122u, ARG125u, ARG90u, ASP364T, ASP378T, GLU112u, GLU354T, GLU360T, GLU379T, GLU46u, HIS361T, LYS108u, LYS111u, LYS124u, LYS52u, TYR115u
• T-v: ARG125v, ARG376T, ASN380T, ASP367T, ASP368T, ASP378T, ASP383T, GLU112v, GLU379T, HIS85v, LYS102v, LYS108v, THR377T
• U-X: ALA107X, ALA110X, ALA17U, ALA195X, ALA21U, ALA400U, ALA407U, ALA408U, ALA411U, ALA416U, ALA431U, ALA442U, ARG103X, ARG116X, ARG145X, ARG146X, ARG14U, ARG171U, ARG269U, ARG26U, ARG273U, ARG274U, ARG27U, ARG321U, ARG328U, ARG330U, ARG343U, ARG376X, ARG37X, ARG441U, ARG511U, ARG513U, ARG532U, ARG54X, ARG61X, ARG65X, ARG72X, ARG81U, ARG87U, ARG99X, ASN105X, ASN112X, ASN141X, ASN161U, ASN182X, ASN203X, ASN205X, ASN31U, ASN394X, ASN426U, ASN436U, ASN439U, ASN452U, ASN6U, ASN74X, ASP131X, ASP134X, ASP159U, ASP166U, ASP169U, ASP16U, ASP186X, ASP196X, ASP206X, ASP215X, ASP23U, ASP312U, ASP325U, ASP339U, ASP364X, ASP367X, ASP378U, ASP383U, ASP421U, ASP42X, ASP433U, ASP43X, ASP443U, ASP519U, ASP561X, ASP570X, ASP58X, ASP84U, ASP89U, ASP92U, ASP92X, CYS516U, GLN135X, GLN142X, GLN181X, GLN214X, GLN218X, GLN270U, GLN327U, GLN399U, GLN40X, GLN429U, GLN437U, GLN56X, GLN73X, GLU117X, GLU120X, GLU133X, GLU147X, GLU185X, GLU189X, GLU227U, GLU230U, GLU24U, GLU28U, GLU296U, GLU306U, GLU311U, GLU314U, GLU317U, GLU354U, GLU393U, GLU396U, GLU396X, GLU414U, GLU423X, GLU445U, GLU515U, GLU566X, GLU5U, GLU70X, GLY183X, GLY305U, GLY308U, GLY318U, GLY326U, GLY419U, GLY427U, GLY428U, GLY512U, GLY55X, GLY96X, HIS104X, HIS150X, HIS155X, HIS172U, HIS177X, ILE109X, ILE113X, ILE119U, ILE149X, ILE176X, ILE217X, ILE271U, ILE510U, LEU164U, LEU212X, LEU322U, LEU329U, LEU33X, LEU374X, LEU418U, LEU438U, LEU444U, LEU453U, LEU67U, LEU67X, LYS108X, LYS163U, LYS167U, LYS190X, LYS229U, LYS248U, LYS272U, LYS30U, LYS313U, LYS324U, LYS346U, LYS346X, LYS347X, LYS348U, LYS413U, LYS413X, LYS528U, LYS528X, LYS563X, LYS583U, LYS66X, LYS83U, PHE187X, PHE209X, PHE222U, PHE309U, PHE351U, PHE35X, PHE432U, PHE449U, PHE57X, PRO137X, PRO148X, PRO204X, PRO210X, PRO302U, PRO349U, PRO395X, PRO62X, PRO75X, PRO82U, SER136X, SER13U, SER151X, SER154X, SER160U, SER162U, SER168U, SER178X, SER180X, SER22U, SER36X, SER39X, SER410U, SER69X, THR100X, THR106X, THR138X, THR20U, THR213X, THR216X, THR323U, THR409U, THR417U, THR434U, THR518U, TRP184X, TRP211X, TRP307U, TRP41X, TRP44X, TYR132X, TYR246U, TYR316U, TYR372X, TYR391X, TYR48X, TYR514U, TYR517U, TYR53X, VAL143X, VAL208X, VAL225U, VAL226U, VAL301U, VAL310U, VAL315U, VAL319U, VAL320U, VAL412U, VAL415U, VAL420U, VAL425U, VAL430U, VAL435U, VAL59X, VAL60X, VAL63U, VAL63X, VAL64X, VAL68X
• U-q: ALA126q, ARG125q, ARG343U, ARG54U, ASN138q, ASP339U, GLN52U, GLY137q, TYR128q, TYR53U
• U-r: ARG131-3.5389732.954599, ARG131-7.1314733.257084, ARG131r, ARG54U, ASP325U, ASP339U, GLN52U, SER130-3.8712433.238047, SER136-3.1476133.246829, TYR53U
• U-s: ARG125s, ARG376U, ASN380U, ASP367U, ASP368U, ASP378U, ASP383U, GLU112s, GLU379U, HIS85s, LYS102s, LYS108s, THR377U
• U-t: ARG122t, ARG125t, ARG90t, ASP364U, ASP378U, GLU112t, GLU354U, GLU360U, GLU379U, GLU46t, HIS361U, LYS108t, LYS111t, LYS124t, LYS52t, TYR115t
• V-W: ALA107W, ALA110W, ALA17V, ALA195W, ALA21V, ALA338W, ALA342V, ALA342W, ALA357V, ALA390V, ALA390W, ALA400V, ALA400W, ALA402V, ALA402W, ALA407V, ALA408V, ALA411V, ALA416V, ALA424W, ALA431V, ALA442V, ALA572W, ALA86V, ALA90V, ALA91V, ARG103W, ARG116W, ARG145W, ARG146W, ARG14V, ARG171V, ARG269V, ARG26V, ARG273V, ARG274V, ARG27V, ARG321V, ARG328V, ARG330V, ARG330W, ARG343V, ARG343W, ARG376W, ARG37W, ARG441V, ARG511V, ARG513V, ARG532V, ARG532W, ARG54W, ARG569V, ARG569W, ARG61W, ARG65W, ARG72W, ARG81V, ARG87V, ARG99W, ASN105W, ASN112W, ASN141W, ASN161V, ASN182W, ASN203W, ASN205W, ASN31V, ASN337V, ASN337W, ASN366V, ASN366W, ASN375W, ASN380V, ASN394V, ASN394W, ASN401V, ASN401W, ASN426V, ASN436V, ASN439V, ASN452V, ASN531V, ASN531W, ASN573V, ASN573W, ASN6V, ASN74W, ASP131W, ASP134W, ASP159V, ASP166V, ASP169V, ASP16V, ASP186W, ASP196W, ASP206W, ASP215W, ASP23V, ASP312V, ASP325V, ASP339V, ASP339W, ASP364V, ASP364W, ASP367W, ASP368W, ASP378V, ASP383V, ASP383W, ASP421V, ASP42W, ASP433V, ASP43W, ASP443V, ASP519V, ASP561W, ASP570W, ASP58W, ASP84V, ASP89V, ASP92V, ASP92W, CYS516V, GLN135W, GLN142W, GLN181W, GLN214W, GLN218W, GLN270V, GLN327V, GLN327W, GLN355V, GLN355W, GLN387V, GLN387W, GLN399V, GLN399W, GLN40W, GLN429V, GLN437V, GLN525W, GLN529W, GLN530V, GLN530W, GLN544W, GLN550V, GLN555V, GLN555W, GLN56W, GLN575W, GLN591W, GLN73W, GLU117W, GLU120W, GLU133W, GLU147W, GLU185W, GLU189W, GLU227V, GLU230V, GLU24V, GLU28V, GLU296V, GLU306V, GLU311V, GLU314V, GLU317V, GLU354V, GLU360V, GLU379V, GLU393V, GLU393W, GLU396V, GLU396W, GLU406W, GLU414V, GLU423V, GLU423W, GLU445V, GLU462V, GLU495V, GLU515V, GLU534V, GLU537V, GLU548V, GLU548W, GLU566W, GLU585V, GLU588W, GLU595W, GLU5V, GLU70W, GLY183W, GLY305V, GLY308V, GLY318V, GLY326V, GLY365V, GLY365W, GLY382V, GLY382W, GLY419V, GLY427V, GLY428V, GLY512V, GLY545V, GLY55W, GLY562W, GLY564W, GLY580V, GLY85V, GLY96W, HIS104W, HIS150W, HIS155W, HIS172V, HIS177W, HIS361V, ILE109W, ILE113W, ILE119V, ILE149W, ILE176W, ILE217W, ILE271V, ILE333V, ILE333W, ILE340V, ILE340W, ILE356V, ILE356W, ILE510V, ILE535V, ILE535W, LEU164V, LEU212W, LEU322V, LEU329V, LEU33W, LEU373W, LEU374W, LEU384V, LEU384W, LEU389V, LEU389W, LEU405V, LEU405W, LEU418V, LEU438V, LEU444V, LEU453V, LEU536W, LEU538V, LEU539V, LEU539W, LEU551V, LEU552W, LEU553W, LEU554V, LEU559W, LEU560V, LEU560W, LEU576V, LEU67V, LEU67W, LEU79V, LYS108W, LYS163V, LYS167V, LYS190W, LYS229V, LYS248V, LYS272V, LYS30V, LYS313V, LYS324V, LYS346V, LYS346W, LYS347V, LYS347W, LYS348V, LYS348W, LYS413V, LYS413W, LYS528V, LYS528W, LYS541V, LYS563W, LYS574W, LYS582V, LYS583V, LYS66W, LYS83V, PHE187W, PHE209W, PHE222V, PHE309V, PHE336V, PHE350V, PHE351V, PHE351W, PHE359V, PHE359W, PHE35W, PHE432V, PHE449V, PHE524W, PHE557V, PHE557W, PHE57W, PRO137W, PRO148W, PRO204W, PRO210W, PRO302V, PRO345V, PRO345W, PRO349V, PRO349W, PRO353V, PRO370W, PRO385V, PRO385W, PRO388V, PRO388W, PRO395V, PRO395W, PRO398V, PRO398W, PRO543V, PRO547V, PRO587W, PRO62W, PRO75W, PRO82V, PRO88V, SER136W, SER13V, SER151W, SER154W, SER160V, SER162V, SER168V, SER178W, SER180W, SER22V, SER335W, SER36W, SER381V, SER39W, SER410V, SER523W, SER526W, SER69W, THR100W, THR106W, THR138W, THR20V, THR213W, THR216W, THR323V, THR344V, THR344W, THR377V, THR377W, THR386V, THR386W, THR409V, THR409W, THR417V, THR422V, THR434V, THR446V, THR518V, THR542V, THR546V, THR558V, THR558W, TRP184W, TRP211W, TRP307V, TRP352V, TRP41W, TRP44W, TRP592W, TYR132W, TYR246V, TYR316V, TYR363V, TYR363W, TYR369W, TYR371W, TYR372W, TYR391V, TYR391W, TYR392V, TYR403V, TYR403W, TYR48W, TYR514V, TYR517V, TYR53W, TYR549W, TYR556W, TYR571W, TYR80V, VAL143W, VAL208W, VAL225V, VAL226V, VAL301V, VAL310V, VAL315V, VAL319V, VAL320V, VAL341W, VAL397V, VAL397W, VAL412V, VAL415V, VAL420V, VAL425V, VAL430V, VAL435V, VAL497V, VAL520V, VAL565W, VAL581V, VAL59W, VAL60W, VAL63V, VAL63W, VAL64W, VAL68W, VAL93V
• V-k: ARG122k, ARG125k, ARG90k, ASP364V, ASP378V, GLU112k, GLU354V, GLU360V, GLU379V, GLU46k, HIS361V, LYS108k, LYS111k, LYS124k, LYS52k
• V-m: ARG125m, ARG376V, ASN380V, ASP367V, ASP368V, ASP378V, ASP383V, GLU112m, GLU379V, HIS85m, LYS102m, LYS108m, THR377V
• V-u: ARG131u, ARG54V, ASP325V, ASP339V, SER136u, TYR53V
• V-v: ALA126v, ARG125v, ARG343V, ARG54V, ASN138v, ASP339V, GLY137v, TYR128v, TYR53V
• W-k: ARG125k, ARG376W, ASN380W, ASP367W, ASP368W, ASP378W, ASP383W, GLU112k, GLU379W, HIS85k, LYS102k, LYS108k, THR377W
• W-s: ARG131s, ARG54W, ASP325W, ASP339W, SER136s, TYR53W
• W-u: ALA126u, ARG125u, ARG343W, ARG54W, ASN138u, ASP339W, GLN52W, GLY137u, TYR128u, TYR53W
• W-v: ARG122v, ARG125v, ARG90v, ASP364W, ASP378W, GLU112v, GLU354W, GLU360W, GLU379W, GLU46v, HIS361W, LYS108v, LYS111v, LYS124v, LYS52v, TYR115v
• X-p: ARG131p, ARG54X, ASP325X, ASP339X, SER136p
• X-q: ARG122q, ARG125q, ARG90q, ASN380X, ASN86q, ASP364X, ASP378X, GLU112q, GLU354X, GLU360X, GLU379X, GLU46q, HIS361X, LYS108q, LYS111q, LYS124q, LYS52q, TYR115q
• X-r: ALA126-7.0568892.477346, ARG125r, ARG343X, ARG54X, ASN138-6.4961143.166672, GLY137-10.6451022.962501, TYR128-10.7829122.993889, TYR53X
• X-t: ARG125t, ARG376X, ASN380X, ASP367X, ASP368X, ASP378X, ASP383X, GLU112t, GLU379X, HIS85t, LYS102t, LYS108t, THR377X
• k-m: ARG15m, ARG76m, ARG90k, ASP22m, ASP27m, ASP35k, ASP38k, ASP39k, ASP50k, ASP94k, GLU46k, GLU98k, HIS85m, LYS102m, LYS111k, TYR109m
• k-v: ARG15k, ARG76k, ARG90v, ASP22k, ASP27k, ASP35v, ASP38v, ASP39v, ASP50v, ASP94v, GLU46v, GLU98v, HIS85k, LYS102k
• l-m: ARG15l, ARG76l, ARG90m, ASP22l, ASP27l, ASP35m, ASP38m, ASP39m, ASP50m, ASP94m, GLU46m, GLU98m, HIS85l, LYS102l
• l-n: ARG15n, ARG76n, ARG90l, ASP22n, ASP27n, ASP35l, ASP38l, ASP39l, ASP50l, ASP94l, GLU46l, GLU98l, HIS85n, LYS102n, LYS111l, TYR109n
• n-o: ARG15o, ARG76o, ARG90n, ASP22o, ASP27o, ASP35n, ASP38n, ASP39n, ASP50n, ASP94n, GLU46n, GLU98n, HIS85o, LYS102o, LYS111n, TYR109o
• o-p: ARG15p, ARG76p, ARG90o, ASP22p, ASP27p, ASP35o, ASP38o, ASP39o, ASP50o, ASP94o, GLU46o, GLU98o, HIS85p, LYS102p, LYS111o, TYR109p
• p-r: ARG15r, ARG76r, ARG90p, ASP22r, ASP27r, ASP35p, ASP38p, ASP39p, ASP50p, ASP94p, GLU46p, GLU98p, HIS85r, LYS102r, LYS111p, TYR109-3.3964752.995365
• q-r: ARG15q, ARG76q, ARG90r, ASP22q, ASP27q, ASP35r, ASP38r, ASP39r, ASP50r, ASP94r, GLN49-5.9330073.253578, GLU46r, GLU98r, HIS85q, LEU113q, LYS102q
• q-t: ARG15t, ARG76t, ARG90q, ASP22t, ASP27t, ASP35q, ASP38q, ASP39q, ASP50q, ASP94q, GLN49q, GLU46q, GLU98q, HIS85t, LEU113t, LYS102t, LYS111q, TYR109t
• s-t: ARG15s, ARG76s, ARG90t, ASP22s, ASP27s, ASP35t, ASP38t, ASP39t, ASP50t, ASP94t, GLU46t, GLU98t, HIS85s, LYS102s
• s-u: ARG15u, ARG76u, ARG90s, ASP22u, ASP27u, ASP35s, ASP38s, ASP39s, ASP50s, ASP94s, GLU46s, GLU98s, HIS85u, LYS102u, LYS111s, TYR109u
• u-v: ARG15v, ARG76v, ARG90u, ASP22v, ASP27v, ASP35u, ASP38u, ASP39u, ASP50u, ASP94u, GLU46u, GLU98u, HIS85v, LYS102v, LYS111u, TYR109v