1VRG

crystal structure of propionyl-coa carboxylase, beta subunit (tm0716) from thermotoga maritima at 2.30 a resolution

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 410
  • Norm. En. per Res.: -4.4057
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-78.9077	-36.5825	-230.875	-346.3652	115	15	7	11050	5	53	55
A-C	-48.6301	-15.2224	-235.06	-298.9125	112	11	8	10853	3	54	54
A-D	-199.9775	-213.1702	-1393.19	-1806.3377	410	51	74	56730	13	98	115
A-E	0.0	0.0	-9.3243	-9.3243	10	0	0	466	0	2	1
A-F	-14.0793	-13.1867	-36.6399	-63.9059	22	1	0	1246	10	22	14
B-C	-71.3874	-37.3859	-245.56	-354.3333	114	10	8	11257	5	53	55
B-D	-16.7788	-18.6608	-33.5797	-69.0194	22	2	0	1262	10	22	14
B-E	-185.5739	-198.2174	-1382.38	-1766.1714	412	51	75	56808	13	98	117
B-F	-12.2821	0.0	-4.0743	-16.3565	10	5	0	416	0	2	0
C-D	-8.9397	0.0	-6.9733	-15.913	10	1	0	388	0	3	1
C-E	-16.4647	-13.9226	-35.0574	-65.4447	24	1	0	1289	9	21	14
C-F	-184.0603	-205.718	-1373.08	-1762.8583	409	44	74	56420	10	98	116
D-E	-59.6073	-39.2328	-252.326	-351.166	117	10	7	11252	6	53	54
D-F	-71.681	-40.7588	-245.95	-358.3898	114	9	7	11230	6	55	55
E-F	-68.7959	-32.4241	-226.207	-327.427	117	14	7	10855	5	50	54

Interface residues

• A-B: ALA117B, ALA252B, ALA417A, ALA422A, ALA426A, ALA472A, ALA473A, ALA494A, ALA89B, ARG400A, ARG475A, ARG485A, ARG493A, ARG4B, ARG505A, ARG60B, ASN250B, ASN468A, ASP115B, ASP269A, ASP272A, ASP276A, ASP418A, ASP479A, ASP483A, ASP54B, ASP5B, ASP74B, CYS498A, GLN316A, GLN464A, GLU14B, GLU253B, GLU268A, GLU427A, GLU486A, GLU496A, GLU499A, GLU503A, GLU52B, GLU58B, GLU82B, GLU8B, GLU9B, GLY121B, GLY416A, GLY476A, GLY48B, GLY79B, GLY81B, HIS59B, ILE122B, ILE13B, ILE17B, ILE270A, ILE273A, ILE471A, ILE482A, ILE53B, ILE7B, LEU10B, LEU116B, LEU118B, LEU264A, LEU271A, LEU274A, LEU399A, LEU3B, LEU421A, LEU495A, LYS108B, LYS109B, LYS112B, LYS119B, LYS11B, LYS12B, LYS394A, LYS413A, LYS463A, LYS489A, LYS501A, LYS55B, LYS6B, LYS87B, PHE50B, PHE56B, PRO275A, PRO278A, PRO393A, PRO424A, PRO469A, PRO47B, PRO484A, SER249B, SER2B, SER425A, SER474A, THR391A, THR49B, THR500A, TRP423A, TYR470A, TYR477A, TYR490A, TYR504A, VAL158B, VAL420A, VAL478A, VAL481A, VAL497A, VAL502A, VAL51B, VAL57B, VAL80B, VAL88B
• A-C: ALA117A, ALA252A, ALA417C, ALA422C, ALA426C, ALA472C, ALA473C, ALA494C, ALA89A, ARG400C, ARG475C, ARG485C, ARG493C, ARG4A, ARG505C, ARG60A, ARG73A, ASN250A, ASN468C, ASP269C, ASP272C, ASP276C, ASP418C, ASP479C, ASP483C, ASP54A, ASP5A, ASP74A, CYS498C, GLN316C, GLN464C, GLU14A, GLU253A, GLU268C, GLU427C, GLU486C, GLU496C, GLU499C, GLU503C, GLU52A, GLU58A, GLU82A, GLU8A, GLU9A, GLY121A, GLY416C, GLY476C, GLY48A, GLY81A, HIS59A, ILE122A, ILE13A, ILE17A, ILE270C, ILE273C, ILE471C, ILE482C, ILE53A, ILE7A, LEU10A, LEU116A, LEU118A, LEU271C, LEU274C, LEU399C, LEU3A, LEU421C, LEU495C, LYS108A, LYS109A, LYS112A, LYS119A, LYS11A, LYS394C, LYS413C, LYS463C, LYS489C, LYS501C, LYS55A, LYS6A, LYS87A, PHE50A, PHE56A, PRO275C, PRO278C, PRO393C, PRO424C, PRO469C, PRO47A, PRO484C, SER249A, SER2A, SER425C, SER474C, THR391C, THR49A, THR500C, TRP423C, TYR470C, TYR477C, TYR490C, TYR504C, VAL158A, VAL420C, VAL478C, VAL481C, VAL497C, VAL502C, VAL51A, VAL57A, VAL80A, VAL88A
• A-D: ALA133A, ALA133D, ALA141A, ALA141D, ALA143A, ALA143D, ALA155A, ALA155D, ALA170A, ALA170D, ALA173A, ALA173D, ALA178A, ALA178D, ALA202A, ALA202D, ALA226A, ALA226D, ALA252A, ALA252D, ALA305A, ALA305D, ALA342A, ALA342D, ALA343A, ALA343D, ALA351A, ALA351D, ALA370A, ALA370D, ALA381A, ALA381D, ALA386A, ALA386D, ALA390A, ALA390D, ALA402A, ALA402D, ALA406A, ALA406D, ALA409A, ALA409D, ALA417A, ALA417D, ALA429A, ALA429D, ALA436A, ALA436D, ALA437A, ALA437D, ALA467A, ALA467D, ALA472A, ALA472D, ALA473A, ALA473D, ARG134A, ARG134D, ARG151A, ARG151D, ARG191A, ARG191D, ARG344A, ARG344D, ARG347A, ARG347D, ARG378A, ARG378D, ARG475A, ARG475D, ARG505A, ARG505D, ARG60A, ARG60D, ASN152A, ASN152D, ASN198A, ASN198D, ASN225A, ASN225D, ASN251A, ASN251D, ASN353A, ASN353D, ASN438A, ASN438D, ASN468A, ASN468D, ASN512A, ASN512D, ASN61A, ASN61D, ASP140A, ASP140D, ASP181A, ASP181D, ASP212A, ASP212D, ASP335A, ASP335D, ASP337A, ASP337D, ASP340A, ASP340D, ASP350A, ASP350D, CYS169A, CYS169D, GLN136A, GLN136D, GLN161A, GLN161D, GLN210A, GLN210D, GLN301A, GLN301D, GLN371A, GLN371D, GLN465A, GLN465D, GLU104A, GLU104D, GLU137A, GLU137D, GLU147A, GLU147D, GLU206A, GLU206D, GLU207A, GLU207D, GLU211A, GLU211D, GLU372A, GLU372D, GLU389A, GLU389D, GLU444A, GLU444D, GLU461A, GLU461D, GLU503A, GLU503D, GLY132A, GLY132D, GLY138A, GLY138D, GLY144A, GLY144D, GLY146A, GLY146D, GLY157A, GLY157D, GLY171A, GLY171D, GLY172A, GLY172D, GLY196A, GLY196D, GLY205A, GLY205D, GLY214A, GLY214D, GLY215A, GLY215D, GLY224A, GLY224D, GLY364A, GLY364D, GLY368A, GLY368D, GLY374A, GLY374D, GLY375A, GLY375D, GLY380A, GLY380D, GLY404A, GLY404D, GLY405A, GLY405D, GLY416A, GLY416D, GLY432A, GLY432D, GLY435A, GLY435D, GLY511A, GLY511D, GLY65A, GLY65D, HIS219A, HIS219D, HIS227A, HIS227D, HIS373A, HIS373D, HIS379A, HIS379D, HIS414A, HIS414D, HIS510A, HIS510D, ILE135A, ILE135D, ILE148A, ILE148D, ILE165A, ILE165D, ILE183A, ILE183D, ILE194A, ILE194D, ILE200A, ILE200D, ILE208A, ILE208D, ILE336A, ILE336D, ILE346A, ILE346D, ILE354A, ILE354D, ILE356A, ILE356D, ILE376A, ILE376D, ILE377A, ILE377D, ILE408A, ILE408D, ILE428A, ILE428D, ILE439A, ILE439D, ILE440A, ILE440D, ILE471A, ILE471D, ILE513A, ILE513D, LEU102A, LEU102D, LEU118A, LEU118D, LEU142A, LEU142D, LEU150A, LEU150D, LEU154A, LEU154D, LEU179A, LEU179D, LEU213A, LEU213D, LEU334A, LEU334D, LEU349A, LEU349D, LEU366A, LEU366D, LEU383A, LEU383D, LEU384A, LEU384D, LEU415A, LEU415D, LEU458A, LEU458D, LEU515A, LEU515D, LEU66D, LYS108A, LYS108D, LYS119D, LYS201A, LYS201D, LYS222A, LYS222D, LYS341A, LYS341D, LYS382A, LYS382D, LYS394A, LYS394D, LYS413A, LYS413D, LYS442A, LYS442D, LYS501A, LYS501D, LYS507A, LYS507D, LYS508A, LYS508D, LYS509A, LYS509D, PHE149A, PHE149D, PHE182A, PHE182D, PHE193A, PHE193D, PHE304A, PHE304D, PHE345A, PHE345D, PHE348A, PHE348D, PHE352A, PHE352D, PHE441A, PHE441D, PHE466A, PHE466D, PHE64A, PHE64D, PRO160A, PRO160D, PRO177A, PRO177D, PRO197A, PRO197D, PRO367A, PRO367D, PRO393A, PRO393D, PRO433A, PRO469A, PRO469D, PRO506A, PRO506D, PRO514A, PRO514D, SER156A, SER156D, SER176A, SER176D, SER209A, SER209D, SER223A, SER223D, SER339A, SER339D, SER388A, SER388D, SER412A, SER412D, SER474A, SER474D, THR153A, THR153D, THR180A, THR180D, THR195A, THR195D, THR204A, THR204D, THR391A, THR391D, THR62A, THR62D, TYR145A, TYR145D, TYR175A, TYR175D, TYR365A, TYR365D, TYR385A, TYR385D, TYR387A, TYR387D, TYR403A, TYR403D, TYR407A, TYR407D, TYR462A, TYR462D, TYR470A, TYR470D, TYR477A, TYR477D, TYR504A, TYR504D, TYR63A, TYR63D, VAL111A, VAL139A, VAL139D, VAL158A, VAL158D, VAL159A, VAL159D, VAL174A, VAL174D, VAL199A, VAL199D, VAL203A, VAL203D, VAL218A, VAL218D, VAL333A, VAL333D, VAL369A, VAL369D, VAL392A, VAL392D, VAL430A, VAL430D, VAL478A, VAL478D
• A-E: ARG505A, ARG505E, LYS507A, LYS507E, PRO506A, PRO506E, TYR504A, TYR504E, VAL502A, VAL502E
• A-F: ARG60A, ARG60F, ASN61A, ASN61F, ASP140A, ASP140F, ASP67A, ASP67F, GLU104A, GLU104F, GLU137A, GLU137F, HIS59A, HIS59F, LEU150A, LYS108A, LYS108F, LYS119F, THR62A, THR62F, TYR63A, TYR63F
• B-C: ALA117C, ALA252C, ALA417B, ALA422B, ALA426B, ALA472B, ALA473B, ALA494B, ALA89C, ARG400B, ARG475B, ARG485B, ARG493B, ARG4C, ARG505B, ARG60C, ASN250C, ASN468B, ASP115C, ASP269B, ASP272B, ASP276B, ASP418B, ASP46C, ASP479B, ASP483B, ASP54C, ASP5C, ASP74C, CYS498B, GLN464B, GLU14C, GLU253C, GLU268B, GLU427B, GLU486B, GLU496B, GLU499B, GLU503B, GLU52C, GLU58C, GLU82C, GLU8C, GLU9C, GLY121C, GLY416B, GLY476B, GLY48C, GLY79C, GLY81C, HIS59C, ILE122C, ILE13C, ILE17C, ILE270B, ILE273B, ILE471B, ILE482B, ILE53C, ILE7C, LEU10C, LEU116C, LEU118C, LEU264B, LEU271B, LEU274B, LEU399B, LEU3C, LEU421B, LEU495B, LYS108C, LYS109C, LYS112C, LYS119C, LYS11C, LYS12C, LYS394B, LYS413B, LYS463B, LYS489B, LYS501B, LYS55C, LYS6C, LYS87C, PHE50C, PHE56C, PRO275B, PRO278B, PRO393B, PRO424B, PRO469B, PRO47C, PRO484B, SER249C, SER2C, SER425B, SER474B, THR391B, THR49C, THR500B, TRP423B, TYR470B, TYR477B, TYR490B, TYR504B, VAL420B, VAL478B, VAL481B, VAL497B, VAL502B, VAL51C, VAL57C, VAL80C, VAL88C
• B-D: ARG60B, ARG60D, ASN61B, ASN61D, ASP140B, ASP140D, ASP67B, ASP67D, GLU104B, GLU104D, GLU137B, GLU137D, HIS59B, HIS59D, LEU150B, LYS108B, LYS108D, LYS119D, THR62B, THR62D, TYR63B, TYR63D
• B-E: ALA133B, ALA133E, ALA141B, ALA141E, ALA143B, ALA143E, ALA155B, ALA155E, ALA170B, ALA170E, ALA173B, ALA173E, ALA178B, ALA178E, ALA202B, ALA202E, ALA226B, ALA226E, ALA252B, ALA252E, ALA305B, ALA305E, ALA342B, ALA342E, ALA343B, ALA343E, ALA351B, ALA351E, ALA370B, ALA370E, ALA381B, ALA381E, ALA386B, ALA386E, ALA390B, ALA390E, ALA402B, ALA402E, ALA406B, ALA406E, ALA409B, ALA409E, ALA417B, ALA417E, ALA429B, ALA429E, ALA436B, ALA436E, ALA437B, ALA437E, ALA467B, ALA467E, ALA472B, ALA472E, ALA473B, ALA473E, ARG134B, ARG134E, ARG151B, ARG151E, ARG191B, ARG191E, ARG344B, ARG344E, ARG347B, ARG347E, ARG378B, ARG378E, ARG443E, ARG475B, ARG475E, ARG505B, ARG505E, ARG60B, ARG60E, ASN152B, ASN152E, ASN198B, ASN198E, ASN225B, ASN225E, ASN251B, ASN251E, ASN353B, ASN353E, ASN438B, ASN438E, ASN468B, ASN468E, ASN512B, ASN512E, ASN61B, ASN61E, ASP140B, ASP140E, ASP181B, ASP181E, ASP212B, ASP212E, ASP335B, ASP335E, ASP337B, ASP337E, ASP340B, ASP340E, ASP350B, ASP350E, CYS169B, CYS169E, GLN136B, GLN136E, GLN161B, GLN161E, GLN210B, GLN210E, GLN301B, GLN301E, GLN371B, GLN371E, GLN465B, GLN465E, GLU104B, GLU104E, GLU137B, GLU137E, GLU147B, GLU147E, GLU206B, GLU206E, GLU207B, GLU207E, GLU211B, GLU211E, GLU372B, GLU372E, GLU389B, GLU389E, GLU444B, GLU444E, GLU461B, GLU461E, GLU503B, GLU503E, GLY131E, GLY132B, GLY138B, GLY138E, GLY144B, GLY144E, GLY146B, GLY146E, GLY157B, GLY157E, GLY171B, GLY171E, GLY172B, GLY172E, GLY196B, GLY196E, GLY205B, GLY205E, GLY214B, GLY214E, GLY215B, GLY215E, GLY224B, GLY224E, GLY364B, GLY364E, GLY368B, GLY368E, GLY374B, GLY374E, GLY375B, GLY375E, GLY380B, GLY380E, GLY404B, GLY404E, GLY405B, GLY405E, GLY416B, GLY416E, GLY432B, GLY432E, GLY435B, GLY435E, GLY511B, GLY511E, GLY65B, GLY65E, HIS219B, HIS219E, HIS227B, HIS227E, HIS373B, HIS373E, HIS379B, HIS379E, HIS414B, HIS414E, HIS510B, HIS510E, ILE135B, ILE135E, ILE148B, ILE148E, ILE165B, ILE165E, ILE183B, ILE183E, ILE194B, ILE194E, ILE200B, ILE200E, ILE208B, ILE208E, ILE336B, ILE336E, ILE346B, ILE346E, ILE354B, ILE354E, ILE356B, ILE356E, ILE376B, ILE376E, ILE377B, ILE377E, ILE408B, ILE408E, ILE428B, ILE428E, ILE439B, ILE439E, ILE440B, ILE440E, ILE471B, ILE471E, ILE513B, ILE513E, LEU102B, LEU102E, LEU118B, LEU118E, LEU142B, LEU142E, LEU150B, LEU150E, LEU154B, LEU154E, LEU179B, LEU179E, LEU213B, LEU213E, LEU334B, LEU334E, LEU349B, LEU349E, LEU366B, LEU366E, LEU383B, LEU383E, LEU384B, LEU384E, LEU415B, LEU415E, LEU458B, LEU458E, LEU515B, LEU515E, LEU66B, LEU66E, LYS108B, LYS108E, LYS119E, LYS201B, LYS201E, LYS222B, LYS222E, LYS341B, LYS341E, LYS382B, LYS382E, LYS394B, LYS394E, LYS413B, LYS413E, LYS442B, LYS442E, LYS501B, LYS501E, LYS507B, LYS507E, LYS508B, LYS508E, LYS509B, LYS509E, PHE149B, PHE149E, PHE182B, PHE182E, PHE193B, PHE193E, PHE304B, PHE304E, PHE345B, PHE345E, PHE348B, PHE348E, PHE352B, PHE352E, PHE441B, PHE441E, PHE466B, PHE466E, PHE64B, PHE64E, PRO160B, PRO160E, PRO177B, PRO177E, PRO197B, PRO197E, PRO367B, PRO367E, PRO393B, PRO393E, PRO433B, PRO469B, PRO469E, PRO506B, PRO506E, PRO514B, PRO514E, SER156B, SER156E, SER176B, SER176E, SER209B, SER209E, SER223B, SER223E, SER339B, SER339E, SER388B, SER388E, SER412B, SER412E, SER474B, SER474E, THR153B, THR153E, THR180B, THR180E, THR195B, THR195E, THR204B, THR204E, THR391B, THR391E, THR62B, THR62E, TYR145B, TYR145E, TYR175B, TYR175E, TYR365B, TYR365E, TYR385B, TYR385E, TYR387B, TYR387E, TYR403B, TYR403E, TYR407B, TYR407E, TYR462B, TYR462E, TYR470B, TYR470E, TYR477B, TYR477E, TYR504B, TYR504E, TYR63B, TYR63E, VAL139B, VAL139E, VAL158B, VAL158E, VAL159B, VAL159E, VAL174B, VAL174E, VAL199B, VAL199E, VAL203B, VAL203E, VAL218B, VAL218E, VAL333B, VAL333E, VAL369B, VAL369E, VAL392B, VAL392E, VAL430B, VAL430E, VAL478B, VAL478E, VAL502E
• B-F: ARG505B, ARG505F, LYS507B, LYS507F, PRO506B, PRO506F, TYR504B, TYR504F, VAL502B, VAL502F
• C-D: ARG505C, ARG505D, LYS507C, LYS507D, PRO506C, PRO506D, TYR504C, TYR504D, VAL502C, VAL502D
• C-E: ARG60C, ARG60E, ASN61C, ASN61E, ASP140C, ASP140E, ASP67C, ASP67E, GLU104C, GLU104E, GLU137C, GLU137E, HIS59C, HIS59E, LEU150C, LEU150E, LYS108C, LYS108E, LYS119C, LYS119E, THR62C, THR62E, TYR63C, TYR63E
• C-F: ALA133C, ALA133F, ALA141C, ALA141F, ALA143C, ALA143F, ALA155C, ALA155F, ALA170C, ALA170F, ALA173C, ALA173F, ALA178C, ALA178F, ALA202C, ALA202F, ALA226C, ALA226F, ALA252C, ALA252F, ALA305C, ALA305F, ALA342C, ALA342F, ALA343C, ALA343F, ALA351C, ALA351F, ALA370C, ALA370F, ALA381C, ALA381F, ALA386C, ALA386F, ALA390C, ALA390F, ALA402C, ALA402F, ALA406C, ALA406F, ALA409C, ALA409F, ALA417C, ALA417F, ALA429C, ALA429F, ALA436C, ALA436F, ALA437C, ALA437F, ALA467C, ALA467F, ALA472C, ALA472F, ALA473C, ALA473F, ARG134C, ARG134F, ARG151C, ARG151F, ARG191C, ARG191F, ARG344C, ARG344F, ARG347C, ARG347F, ARG378C, ARG378F, ARG475C, ARG475F, ARG505C, ARG505F, ARG60C, ARG60F, ASN152C, ASN152F, ASN198C, ASN198F, ASN225C, ASN225F, ASN251C, ASN251F, ASN353C, ASN353F, ASN438C, ASN438F, ASN468C, ASN468F, ASN512C, ASN512F, ASN61C, ASN61F, ASP140C, ASP140F, ASP181C, ASP181F, ASP212C, ASP212F, ASP335C, ASP335F, ASP337C, ASP337F, ASP340C, ASP340F, ASP350C, ASP350F, CYS169C, CYS169F, GLN136C, GLN136F, GLN161C, GLN161F, GLN210C, GLN210F, GLN221C, GLN301C, GLN301F, GLN371C, GLN371F, GLN465C, GLN465F, GLU104C, GLU104F, GLU137C, GLU137F, GLU147C, GLU147F, GLU206C, GLU206F, GLU207C, GLU207F, GLU211C, GLU211F, GLU372C, GLU372F, GLU389C, GLU389F, GLU427C, GLU444C, GLU461C, GLU461F, GLU503C, GLU503F, GLY132C, GLY132F, GLY138C, GLY138F, GLY144C, GLY144F, GLY146C, GLY146F, GLY157C, GLY157F, GLY171C, GLY171F, GLY172C, GLY172F, GLY196C, GLY196F, GLY205C, GLY205F, GLY214C, GLY214F, GLY215C, GLY215F, GLY224C, GLY224F, GLY364C, GLY364F, GLY368C, GLY368F, GLY374C, GLY374F, GLY375C, GLY375F, GLY380C, GLY380F, GLY404C, GLY404F, GLY405C, GLY405F, GLY416C, GLY416F, GLY432C, GLY432F, GLY435C, GLY435F, GLY511C, GLY511F, GLY65C, GLY65F, HIS219C, HIS219F, HIS227C, HIS227F, HIS373C, HIS373F, HIS379C, HIS379F, HIS414C, HIS414F, HIS510C, HIS510F, ILE135C, ILE135F, ILE148C, ILE148F, ILE165C, ILE165F, ILE183C, ILE183F, ILE194C, ILE194F, ILE200C, ILE200F, ILE208C, ILE208F, ILE336C, ILE336F, ILE346C, ILE346F, ILE354C, ILE354F, ILE356C, ILE356F, ILE376C, ILE376F, ILE377C, ILE377F, ILE408C, ILE408F, ILE428C, ILE428F, ILE439C, ILE439F, ILE440C, ILE440F, ILE471C, ILE471F, ILE513C, ILE513F, LEU102C, LEU102F, LEU118C, LEU118F, LEU142C, LEU142F, LEU150C, LEU150F, LEU154C, LEU154F, LEU179C, LEU179F, LEU213C, LEU213F, LEU334C, LEU334F, LEU349C, LEU349F, LEU366C, LEU366F, LEU383C, LEU383F, LEU384C, LEU384F, LEU415C, LEU415F, LEU458C, LEU458F, LEU515C, LEU515F, LEU66F, LYS108C, LYS108F, LYS201C, LYS201F, LYS222C, LYS222F, LYS341C, LYS341F, LYS382C, LYS382F, LYS394C, LYS394F, LYS413C, LYS413F, LYS442C, LYS442F, LYS501C, LYS501F, LYS507C, LYS507F, LYS508C, LYS508F, LYS509C, LYS509F, PHE149C, PHE149F, PHE182C, PHE182F, PHE193C, PHE193F, PHE304C, PHE304F, PHE345C, PHE345F, PHE348C, PHE348F, PHE352C, PHE352F, PHE441C, PHE441F, PHE466C, PHE466F, PHE64C, PHE64F, PRO160C, PRO160F, PRO177C, PRO177F, PRO197C, PRO197F, PRO367C, PRO367F, PRO393C, PRO393F, PRO433C, PRO433F, PRO469C, PRO469F, PRO506C, PRO506F, PRO514C, PRO514F, SER156C, SER156F, SER176C, SER176F, SER209C, SER209F, SER223C, SER223F, SER339C, SER339F, SER388C, SER388F, SER412C, SER412F, SER474C, SER474F, THR153C, THR153F, THR180C, THR180F, THR195C, THR195F, THR204C, THR204F, THR391C, THR391F, THR62C, THR62F, TYR145C, TYR145F, TYR175C, TYR175F, TYR365C, TYR365F, TYR385C, TYR385F, TYR387C, TYR387F, TYR403C, TYR403F, TYR407C, TYR407F, TYR462C, TYR462F, TYR470F, TYR477C, TYR477F, TYR504C, TYR504F, TYR63C, TYR63F, VAL139C, VAL139F, VAL158C, VAL158F, VAL159C, VAL159F, VAL174C, VAL174F, VAL199C, VAL199F, VAL203C, VAL203F, VAL218C, VAL218F, VAL333C, VAL333F, VAL369C, VAL369F, VAL392C, VAL392F, VAL430C, VAL430F, VAL478C, VAL478F
• D-E: ALA117D, ALA252D, ALA417E, ALA422E, ALA426E, ALA472E, ALA473E, ALA494E, ALA89D, ARG400E, ARG475E, ARG485E, ARG493E, ARG4D, ARG505E, ARG60D, ASN250D, ASN468E, ASP115D, ASP269E, ASP272E, ASP276E, ASP418E, ASP46D, ASP479E, ASP483E, ASP54D, ASP5D, ASP74D, CYS498E, GLN316E, GLN464E, GLU14D, GLU253D, GLU268E, GLU427E, GLU486E, GLU496E, GLU499E, GLU503E, GLU52D, GLU58D, GLU82D, GLU8D, GLU9D, GLY121D, GLY416E, GLY476E, GLY48D, GLY79D, GLY81D, HIS59D, ILE122D, ILE13D, ILE17D, ILE270E, ILE273E, ILE471E, ILE482E, ILE53D, ILE7D, LEU10D, LEU113D, LEU116D, LEU118D, LEU264E, LEU271E, LEU274E, LEU399E, LEU3D, LEU421E, LEU495E, LYS108D, LYS109D, LYS112D, LYS119D, LYS11D, LYS12D, LYS394E, LYS413E, LYS463E, LYS489E, LYS501E, LYS55D, LYS6D, LYS87D, PHE50D, PHE56D, PRO275E, PRO278E, PRO393E, PRO424E, PRO469E, PRO47D, PRO484E, SER249D, SER2D, SER425E, SER474E, THR391E, THR49D, THR500E, TRP423E, TYR470E, TYR477E, TYR490E, TYR504E, VAL158D, VAL420E, VAL478E, VAL481E, VAL497E, VAL502E, VAL51D, VAL57D, VAL80D, VAL88D
• D-F: ALA117F, ALA252F, ALA417D, ALA422D, ALA426D, ALA472D, ALA473D, ALA494D, ALA89F, ARG400D, ARG475D, ARG485D, ARG493D, ARG4F, ARG505D, ARG60F, ASN250F, ASN468D, ASP269D, ASP272D, ASP276D, ASP418D, ASP46F, ASP479D, ASP483D, ASP54F, ASP5F, ASP74F, CYS498D, GLN316D, GLN464D, GLU14F, GLU253F, GLU268D, GLU427D, GLU486D, GLU496D, GLU499D, GLU503D, GLU52F, GLU58F, GLU82F, GLU8F, GLU9F, GLY121F, GLY416D, GLY476D, GLY48F, GLY79F, GLY81F, HIS59F, ILE122F, ILE13F, ILE17F, ILE270D, ILE273D, ILE471D, ILE482D, ILE53F, ILE7F, LEU10F, LEU116F, LEU118F, LEU264D, LEU271D, LEU274D, LEU399D, LEU3F, LEU421D, LEU495D, LYS108F, LYS109F, LYS112F, LYS119F, LYS11F, LYS394D, LYS413D, LYS463D, LYS489D, LYS501D, LYS55F, LYS6F, LYS87F, PHE50F, PHE56F, PRO275D, PRO278D, PRO393D, PRO424D, PRO469D, PRO47F, PRO484D, SER249F, SER2F, SER425D, SER474D, THR391D, THR49F, THR500D, TRP423D, TYR470D, TYR477D, TYR490D, TYR504D, VAL158F, VAL420D, VAL478D, VAL481D, VAL497D, VAL502D, VAL51F, VAL57F, VAL80F, VAL88F
• E-F: ALA117E, ALA252E, ALA417F, ALA422F, ALA426F, ALA472F, ALA473F, ALA494F, ALA89E, ARG400F, ARG475F, ARG485F, ARG493F, ARG4E, ARG505F, ARG60E, ASN250E, ASN468F, ASN61E, ASP115E, ASP269F, ASP272F, ASP276F, ASP418F, ASP479F, ASP483F, ASP54E, ASP5E, ASP74E, CYS498F, GLN464F, GLU14E, GLU253E, GLU268F, GLU427F, GLU486F, GLU496F, GLU499F, GLU503F, GLU52E, GLU58E, GLU82E, GLU8E, GLU9E, GLY121E, GLY416F, GLY476F, GLY48E, GLY79E, GLY81E, HIS59E, ILE122E, ILE13E, ILE17E, ILE270F, ILE273F, ILE471F, ILE482F, ILE491F, ILE53E, ILE7E, LEU10E, LEU116E, LEU118E, LEU264F, LEU271F, LEU274F, LEU399F, LEU3E, LEU421F, LEU495F, LYS108E, LYS109E, LYS112E, LYS119E, LYS11E, LYS12E, LYS394F, LYS413F, LYS463F, LYS489F, LYS501F, LYS55E, LYS6E, LYS70E, LYS87E, PHE50E, PHE56E, PRO275F, PRO278F, PRO393F, PRO424F, PRO469F, PRO47E, PRO484F, SER249E, SER2E, SER425F, SER474F, THR391F, THR49E, THR500F, TRP423F, TYR470F, TYR477F, TYR490F, TYR504F, VAL158E, VAL420F, VAL478F, VAL481F, VAL497F, VAL502F, VAL51E, VAL57E, VAL80E, VAL88E