1VPF

structure of human vascular endothelial growth factor

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 30
  • Norm. En. per Res.: -3.1826
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-93.4173	-44.2687	1155.53	1017.844	117	26	10	16073	2	19	19
B-C	-25.4432	-14.6123	-55.4234	-95.4788	30	2	0	1966	6	11	7
B-D	0.0	0.0	-1.1479	-1.1479	4	0	0	101	0	2	0
C-D	-84.8805	-44.6982	1060.8	931.2214	118	25	9	15727	2	17	19

Interface residues

• A-B: ARG23A, ARG23B, ARG56A, ARG56B, ARG82A, ARG82B, ASN62A, ASN62B, ASP19A, ASP19B, ASP34A, ASP34B, ASP63A, ASP63B, CYS26A, CYS26B, CYS51A, CYS51B, CYS57A, CYS57B, CYS60A, CYS60B, CYS61A, CYS61B, CYS68A, CYS68B, GLN22A, GLN22B, GLN79A, GLN79B, GLN89A, GLN89B, GLN98A, GLN98B, GLU30A, GLU30B, GLU64A, GLU64B, GLU93A, GLU93B, GLY58A, GLY58B, GLY59A, GLY59B, GLY92A, GLY92B, HIS27A, HIS27B, ILE29A, ILE29B, ILE35A, ILE35B, ILE46A, ILE46B, ILE76A, ILE76B, ILE80A, ILE80B, ILE83A, ILE91A, ILE91B, LEU32A, LEU32B, LEU54A, LEU54B, LYS16A, LYS16B, LYS48A, LYS48B, MET18A, MET18B, MET55A, MET55B, MET78A, MET78B, MET81A, MET81B, MET94A, MET94B, PHE17A, PHE17B, PHE36A, PHE36B, PHE47A, PHE47B, PHE96A, PHE96B, PRO28A, PRO28B, PRO49A, PRO49B, PRO53A, PRO53B, SER24A, SER24B, SER50A, SER50B, SER95A, SER95B, THR31A, THR31B, THR77A, THR77B, TYR21A, TYR21B, TYR25A, TYR25B, VAL14A, VAL14B, VAL15A, VAL15B, VAL20A, VAL20B, VAL33A, VAL33B, VAL52A, VAL52B
• B-C: ARG105B, ARG82C, ASN100B, ASN75B, GLN79C, GLN87C, GLN89C, GLN98B, GLU103B, GLU72B, GLU73B, GLU93C, GLY88C, GLY92C, HIS90C, HIS99B, ILE76B, ILE80C, ILE91C, LEU97B, LYS101B, MET81C, MET94C, PRO70B, SER74B, SER95C, THR71B, THR77C, TYR45C, VAL69B
• B-D: ARG105B, LYS16D, THR71B, VAL14D
• C-D: ARG23C, ARG23D, ARG56C, ARG56D, ARG82C, ARG82D, ASN62C, ASN62D, ASP19C, ASP19D, ASP34C, ASP34D, ASP63C, ASP63D, CYS26C, CYS26D, CYS51C, CYS51D, CYS57C, CYS57D, CYS60C, CYS60D, CYS61C, CYS61D, CYS68C, CYS68D, GLN22C, GLN22D, GLN79C, GLN79D, GLN89C, GLN89D, GLN98C, GLN98D, GLU30C, GLU30D, GLU64C, GLU64D, GLU93C, GLU93D, GLY58C, GLY58D, GLY59C, GLY59D, GLY92C, GLY92D, HIS27C, HIS27D, HIS90D, ILE29C, ILE29D, ILE35C, ILE35D, ILE46C, ILE46D, ILE76C, ILE76D, ILE80C, ILE80D, ILE83D, ILE91C, ILE91D, LEU32C, LEU32D, LEU54C, LEU54D, LYS16C, LYS16D, LYS48C, LYS48D, MET18C, MET18D, MET55C, MET55D, MET78C, MET78D, MET81C, MET81D, MET94C, MET94D, PHE17C, PHE17D, PHE36C, PHE36D, PHE47C, PHE47D, PHE96C, PHE96D, PRO28C, PRO28D, PRO49C, PRO49D, PRO53C, PRO53D, SER24C, SER24D, SER50C, SER50D, SER95C, SER95D, THR31C, THR31D, THR77C, THR77D, TYR21C, TYR21D, TYR25C, TYR25D, VAL14C, VAL14D, VAL15C, VAL15D, VAL20C, VAL20D, VAL33C, VAL33D, VAL52C, VAL52D