1VOU

crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400.

• Total interactions analyzed: 496
• Total true interactions: 29
• Strongest Interaction:
  • Chains: O-T
  • Int. Res.: 18
  • Norm. En. per Res.: -3.1797
• Hub Node: E(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
E-K	-15.7039	0.0	266.013	250.3091	21	44	1	1818	0	0	4
E-L	-13.9472	10.407	109.598	106.0578	14	22	0	857	0	4	7
E-O	0.0	0.0	-11.6907	-11.6907	9	0	0	696	0	0	6
E-Q	-33.2594	-38.6466	1019.06	947.154	85	261	4	11566	4	13	25
F-M	0.0	12.4513	-16.963	-4.5117	29	1	0	1480	0	13	15
F-R	0.0	0.0	-3.9352	-3.9352	12	0	0	467	0	0	1
F-T	0.0	0.0	-3.1855	-3.1855	8	0	0	274	0	0	0
F-4	0.0	0.0	-0.1801	-0.1801	4	0	0	53	0	0	5
H-6	0.0	0.0	-1.7267	-1.7267	11	0	0	291	0	0	6
I-1	-43.3367	-34.571	377.075	299.1672	36	73	0	3209	2	9	12
J-W	0.0	0.0	-4.2962	-4.2962	10	0	0	296	0	1	3
K-R	0.0	10.622	-27.4845	-16.8625	35	1	1	2108	0	4	20
K-S	0.0	0.0	-2.5078	-2.5078	5	0	0	240	0	0	1
L-Q	-142.5878	64.0123	1311.08	1232.5045	69	239	2	8253	2	26	36
M-S	0.0	9.363	-13.6089	-4.2459	10	0	0	531	0	0	9
M-1	0.0	0.0	-0.0088	-0.0088	3	0	0	8	0	0	0
M-5	-6.9523	25.4455	443.121	461.6141	56	37	0	6388	1	9	48
N-W	-53.4093	-8.7784	2225.04	2162.8523	108	487	10	17244	1	28	40
N-X	0.0	0.0	-0.7313	-0.7313	6	0	0	124	0	0	1
N-6	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	1	1
O-T	-7.3605	-28.3119	-21.563	-57.2355	18	1	0	919	1	4	4
O-2	-12.7605	13.1111	-40.1423	-39.7917	29	6	0	2026	2	3	11
P-X	0.0	14.5713	-11.0271	3.5442	16	0	0	732	0	2	6
R-S	-5.6508	14.0548	228.182	236.5861	93	83	10	9202	0	23	44
R-2	0.0	0.0	84.3182	84.3182	16	19	0	759	0	0	6
T-2	-7.3367	-9.9912	-11.3918	-28.7198	53	18	4	4189	2	19	24
U-Y	0.0	-13.8955	89.2186	75.3231	39	49	3	3737	1	11	10
1-5	0.0	0.0	-0.0218	-0.0218	2	0	0	12	0	0	0
3-5	-13.6719	0.0	24.6735	11.0016	20	17	0	997	0	2	1

Interface residues

• E-K: ARG102K, ARG149E, GLN107K, GLN143E, GLN40E, GLY105K, GLY108K, GLY109K, GLY148E, GLY153E, LEU110K, LYS152E, LYS154E, PRO147E, PRO157K, SER159K, THR104K, TYR103K, TYR106K, TYR151E, VAL150E
• E-L: ALA20E, ALA84L, ARG19E, ARG83L, ASN17E, ASP18E, ASP85L, GLY86L, ILE21E, LYS16E, LYS82L, SER87L, THR12E, TRP15E
• E-O: ASN192E, GLN114E, GLY110E, GLY112E, GLY4O, HIS3O, LYS109E, LYS111E, LYS5O
• E-Q: ALA177E, ALA191E, ALA20E, ALA28E, ALA52E, ALA84Q, ARG14Q, ARG176E, ARG19E, ARG40Q, ARG63Q, ARG76E, ARG9Q, ASN17E, ASN180E, ASN192E, ASN89Q, ASP18E, ASP19Q, GLN13E, GLN18Q, GLN23Q, GLN2Q, GLN90Q, GLU11Q, GLU174E, GLU179E, GLU17Q, GLY10E, GLY10Q, GLY15Q, GLY178E, GLY193E, GLY194E, GLY29E, GLY61Q, GLY6E, HIS20Q, HIS4Q, ILE14E, ILE16Q, ILE175E, ILE182E, ILE5Q, ILE77E, ILE7Q, ILE9E, LEU12Q, LEU13Q, LEU181E, LEU183E, LEU195E, LEU27E, LEU5E, LEU87Q, LYS16E, LYS54E, LYS64Q, LYS6Q, LYS8E, MET11E, PHE66Q, PHE83Q, PRO22E, PRO53E, PRO82Q, PRO86Q, SER62Q, SER65Q, SER85Q, THR12E, THR21Q, THR24E, THR3Q, THR67Q, THR75E, THR7E, TRP15E, TYR51E, VAL196E, VAL25E, VAL26E, VAL39Q, VAL68Q, VAL88Q
• F-M: ALA109F, ARG111F, ARG13M, ARG16M, ARG185F, ARG18M, ASN23F, ASP15M, ASP184F, GLU146F, GLU29F, GLY11M, GLY20M, GLY25F, HIS28F, LEU181F, LEU27F, LYS147F, LYS14M, LYS17M, LYS28M, PHE84F, SER110F, SER12M, SER24F, VAL19M, VAL22F, VAL26F, VAL31F
• F-R: ALA43F, ALA4R, ARG3R, ARG40F, ARG89F, GLY41F, PRO2R, PRO86F, SER44F, THR42F, THR45F, TYR91F
• F-T: ALA67F, ARG111T, GLY112T, GLY65F, HIS69F, SER113T, THR64F, TYR59F
• F-4: ARG334, GLY384, LYS374, LYS53F
• H-6: ALA170H, ALA63H, ARG186, ARG62H, ASN296, GLN168H, GLN59H, GLU167H, ILE169H, LYS172H, VAL306
• I-1: ALA25I, ALA35I, ALA38I, ARG26I, ARG40I, ARG621, ARG681, ASN27I, ASN42I, ASP22I, ASP651, GLN2I, GLU461, GLU471, GLY23I, GLY451, GLY641, GLY701, ILE30I, LEU29I, LEU34I, LYS611, LYS721, LYS731, MET1I, PHE631, PRO31I, SER37I, SER661, SER711, THR39I, THR441, TRP28I, TYR24I, TYR671, VAL36I
• J-W: ALA94J, ARG103W, ASN92J, GLN105W, GLN109W, GLU107W, LYS93J, PRO91J, THR90J, VAL108W
• K-R: ALA100R, ALA67R, ALA69R, ALA96R, ALA99R, ARG101R, ARG53K, ARG59R, ARG63K, ARG64R, ARG67K, ARG70R, ASN66R, ASP69K, ASP97R, GLN63R, GLY64K, GLY68R, HIS66K, ILE62R, ILE98R, LEU171K, LEU60R, LEU71R, LYS30K, LYS65K, PHE57R, PHE70K, PRO72K, SER60K, THR168K, THR31K, THR71K, TRP61R, VAL29K
• K-S: ARG13S, GLN11S, LYS30K, TYR12S, VAL29K
• L-Q: ALA115L, ALA84L, ALA84Q, ARG108Q, ARG111Q, ARG116L, ARG119L, ARG40Q, ARG44Q, ARG69Q, ARG76L, ARG79Q, ARG83L, ARG90L, ARG93L, ASN43Q, ASN89Q, ASN94L, ASP120L, ASP85L, ASP92L, ASP9L, GLN90Q, GLU117L, GLU132L, GLU41Q, GLU51Q, GLU75Q, GLU78Q, GLY112L, GLY42Q, GLY52Q, GLY74Q, GLY76Q, GLY86L, ILE89L, LEU87Q, LYS64Q, LYS82L, PHE111L, PHE123L, PHE66Q, PHE73Q, PHE81Q, PHE83Q, PHE91L, PRO113L, PRO131L, PRO82Q, PRO86Q, SER65Q, SER72Q, SER78L, SER85Q, SER87L, THR45Q, THR67Q, THR77L, THR88L, VAL10L, VAL114L, VAL127L, VAL133L, VAL39Q, VAL53Q, VAL54Q, VAL68Q, VAL77Q, VAL80Q
• M-S: ARG32M, ARG81S, ARG82S, ARG83S, GLY33M, GLY36M, HIS34M, LYS35M, THR84S, TYR80S
• M-1: ARG281, ARG55M, ARG59M
• M-5: ALA105, ALA245, ALA565, ALA58M, ARG125, ARG135, ARG305, ARG53M, ARG55M, ARG575, ARG59M, ARG63M, ARG645, ASN66M, ASN67M, GLU50M, GLU545, GLY285, GLY455, GLY475, GLY51M, GLY52M, GLY64M, GLY69M, HIS315, HIS75, ILE145, ILE57M, LEU56M, LEU605, LEU60M, LYS115, LYS155, LYS265, LYS295, LYS445, LYS525, LYS595, LYS62M, LYS85, MET45, MET585, MET95, PHE255, PHE48M, PHE49M, PHE65M, PRO25, PRO61M, SER275, SER54M, THR65, TRP555, TYR72M, VAL495, VAL68M
• N-W: ALA108N, ALA122N, ALA22N, ALA29N, ALA37N, ALA41N, ALA42W, ALA68W, ALA77W, ARG102N, ARG103W, ARG44W, ARG52N, ARG60N, ARG61N, ARG68N, ARG74W, ARG76W, ASN119W, ASP114W, ASP137W, ASP26N, ASP32N, ASP40W, ASP72W, GLN109W, GLN129N, GLN70W, GLU106N, GLU107W, GLU39N, GLU93W, GLY101N, GLY102W, GLY106W, GLY110W, GLY111W, GLY24N, GLY25N, GLY31N, GLY34N, GLY62N, GLY63N, HIS118W, HIS124N, HIS58N, HIS99W, ILE115W, ILE128N, ILE36N, ILE65N, ILE67N, ILE79W, LEU112W, LEU120W, LEU126N, LEU166W, LEU172W, LEU35N, LYS125N, LYS131N, LYS23N, LYS64N, LYS73W, LYS75W, LYS99N, MET104N, MET38N, MET71W, PHE105N, PHE119N, PHE30N, PHE43W, PHE59N, PRO100N, PRO127N, PRO173W, PRO40N, PRO78W, PRO97W, SER104W, SER170W, SER47W, SER95W, THR100W, THR101W, THR130N, THR167W, TYR27N, TYR33N, TYR66N, VAL103N, VAL107N, VAL110N, VAL113W, VAL116W, VAL117W, VAL168W, VAL169W, VAL171W, VAL28N, VAL66W, VAL69W, VAL81W, VAL94W, VAL97N, VAL98N, VAL98W
• N-X: GLY8X, LYS86N, LYS88N, SER10X, SER9X, VAL7X
• N-6: LYS86, PHE119N
• O-T: ALA64T, ARG103O, ARG104O, ARG58T, ARG62T, ASP106O, GLU66T, GLY101O, GLY105O, GLY107O, ILE60T, LYS70T, PHE59T, PRO61T, PRO67T, SER63T, SER65T, THR102O
• O-2: ALA111O, ARG552, ARG96O, ARG99O, CYS462, GLN562, GLU114O, GLY101O, GLY542, HIS432, HIS442, ILE113O, ILE452, ILE97O, LEU112O, LEU115O, LEU412, LEU582, LEU98O, LYS402, PRO472, SER422, THR102O, THR109O, THR95O, TYR522, VAL100O, VAL116O, VAL572
• P-X: ALA22P, ALA23P, ALA76X, ARG18P, ARG47P, ARG77X, ASP45P, GLN49X, GLY75X, ILE79X, LEU59X, LYS44X, LYS74X, PHE78X, SER24P, THR21P
• R-S: ALA100R, ALA105R, ALA108R, ALA112R, ALA3S, ALA42R, ALA43R, ALA51S, ALA86R, ALA96R, ALA99R, ARG101R, ARG13S, ARG20R, ARG48R, ARG50R, ARG51R, ARG72S, ARG82S, ARG87S, ARG92R, ASN41R, ASN87R, ASN91R, ASP49R, ASP50S, ASP89R, ASP97R, GLN11S, GLN37R, GLN44S, GLN6S, GLN79S, GLN88S, GLU102R, GLU104R, GLU43S, GLU46R, GLU49S, GLY41S, GLY42S, GLY48S, GLY52S, GLY77S, GLY85S, GLY9S, HIS86S, ILE4S, ILE5S, ILE71S, ILE88R, ILE98R, LEU109R, LEU38S, LEU39R, LEU40R, LEU90R, LEU95R, LYS107R, LYS10S, LYS16R, LYS19R, LYS22R, LYS53S, LYS54R, LYS73S, LYS75S, LYS93R, MET1S, PHE24R, PHE2S, PHE36R, PHE39S, PHE47S, PRO103R, SER76S, THR38R, THR44R, THR55S, THR7S, THR84S, TYR12S, TYR45R, TYR47R, TYR54S, TYR70S, TYR74S, VAL14S, VAL17R, VAL40S, VAL46S, VAL78S, VAL94R
• R-2: ARG162, ARG28R, ARG33R, ASN34R, ASP172, GLN31R, GLY26R, LYS102, LYS132, LYS152, MET182, SER122, SER142, SER27R, THR112, TRP25R
• T-2: ALA242, ALA272, ALA53T, ALA64T, ARG111T, ARG162, ARG202, ARG36T, ARG39T, ARG46T, ARG58T, ARG62T, ASN292, ASN482, ASP172, ASP43T, ASP52T, ASP55T, CYS332, CYS462, GLN51T, GLU322, GLU54T, GLY382, GLY47T, HIS232, HIS372, HIS442, ILE45T, ILE60T, LEU252, LEU302, LEU40T, LEU412, LEU56T, LEU57T, LYS132, LYS32, LYS37T, LYS392, LYS402, LYS48T, PHE59T, PRO282, PRO472, PRO61T, SER422, THR262, THR312, VAL41T, VAL42T, VAL44T, VAL50T
• U-Y: ALA32Y, ALA33Y, ALA34Y, ALA41U, ALA45U, ALA92U, ALA9U, ARG21Y, ARG29Y, ARG47Y, ARG75U, ASN73U, ASP19Y, ASP5U, GLN31Y, GLN44U, GLN8U, GLU24Y, GLU27Y, HIS3U, ILE12U, ILE18Y, ILE42U, ILE6U, LEU25Y, LEU28Y, LEU7U, LYS22Y, LYS23Y, MET26Y, PHE30Y, PHE46U, PRO10U, SER2U, SER30U, TRP28U, TYR4U, VAL11U, VAL29U
• 1-5: ARG281, LYS85
• 3-5: ALA23, ARG425, ASN335, GLN325, GLU133, GLY355, HIS315, ILE415, ILE93, LYS113, LYS263, LYS365, SER375, THR233, THR243, THR253, THR345, TYR213, TYR223, VAL103