1VKN

crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (tm1782) from thermotoga maritima at 1.80 a resolution

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 73
  • Norm. En. per Res.: -4.2981
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-64.3259	-17.7567	-231.677	-313.7596	73	8	12	8130	0	23	16
A-C	-2.6487	7.8977	-343.714	-338.4651	119	7	5	13737	0	24	17
A-D	-167.1483	-8.3948	-482.108	-657.6511	163	35	17	20564	8	39	34
B-C	-138.0071	-11.0608	-501.631	-650.6989	164	30	16	20820	10	38	36
B-D	-5.3448	7.7344	-342.541	-340.1513	123	5	5	13851	0	24	20
C-D	-20.1266	0.0	-173.543	-193.6696	66	6	12	6173	0	6	8

Interface residues

• A-B: ALA179A, ALA179B, ARG181A, ARG181B, ARG197B, ARG235A, ARG235B, ASN193A, ASN193B, ASP186A, ASP186B, GLU183A, GLU183B, GLU191A, GLU191B, GLU194A, GLU194B, GLY175A, GLY175B, GLY178A, GLY178B, GLY180A, GLY180B, ILE45A, ILE45B, LEU15A, LEU15B, LEU188A, LEU188B, LEU230A, LEU230B, LEU308A, LEU308B, LYS182A, LYS182B, LYS184A, LYS184B, LYS278A, LYS278B, PHE189A, PHE189B, PHE46A, PHE46B, PRO232A, PRO232B, PRO339A, PRO339B, SER177A, SER177B, SER190A, SER190B, SER195A, SER195B, THR234A, THR234B, THR36A, THR36B, TYR12A, TYR12B, TYR187A, TYR187B, TYR281A, TYR281B, TYR37A, TYR37B, VAL176A, VAL176B, VAL185A, VAL185B, VAL192A, VAL192B, VAL231A, VAL231B
• A-C: ARG19A, ARG19C, ARG235A, ARG235C, ASN193A, ASN193C, ASN23A, ASN23C, ASN284A, ASN284C, ASN307A, ASN307C, ASP306A, ASP306C, CYS280A, CYS280C, GLU16A, GLU16C, GLU194A, GLU194C, GLU333A, GLU333C, GLU43A, GLU43C, GLU44A, GLU44C, GLU51A, GLU51C, GLY11A, GLY11C, GLY282A, GLY282C, HIS267A, HIS267C, HIS285A, HIS285C, ILE273A, ILE273C, ILE337A, ILE337C, ILE45A, ILE45C, LEU15A, LEU15C, LEU20A, LEU20C, LEU269A, LEU269C, LEU308A, LEU308C, LEU50A, LEU50C, LYS22A, LYS22C, LYS278A, LYS278C, LYS41A, LYS41C, PHE189A, PHE189C, PHE265A, PHE265C, PHE287A, PHE287C, PHE334A, PHE334C, PHE46A, PHE46C, PRO232A, PRO232C, PRO264A, PRO264C, PRO270A, PRO270C, PRO275A, PRO275C, PRO336A, PRO336C, PRO339A, PRO339C, PRO47A, PRO47C, SER177A, SER177C, SER190C, SER276A, SER276C, SER283A, SER283C, SER48A, SER48C, THR10A, THR13A, THR13C, THR234A, THR234C, THR335A, THR335C, THR49A, THR49C, TRP279A, TRP279C, TYR12A, TYR12C, TYR274A, TYR274C, TYR281A, TYR281C, TYR338A, TYR338C, VAL176A, VAL176C, VAL18A, VAL18C, VAL266C, VAL286A, VAL286C, VAL309A, VAL309C
• A-D: ALA172A, ALA172D, ALA202A, ALA202D, ALA304A, ALA304D, ARG197A, ARG197D, ARG235A, ARG235D, ARG295A, ARG295D, ASN193A, ASN193D, ASN200A, ASN200D, ASN223A, ASN223D, ASN297A, ASN297D, ASP171A, ASP171D, ASP186A, ASP186D, CYS280A, CYS280D, GLN291A, GLN291D, GLU166A, GLU166D, GLU191A, GLU191D, GLU194A, GLU194D, GLU211A, GLU211D, GLU293A, GLU293D, GLU294A, GLU294D, GLY175A, GLY175D, GLY236A, GLY236D, GLY272A, GLY272D, GLY289A, GLY289D, HIS204A, HIS204D, HIS229A, HIS229D, ILE168A, ILE168D, ILE237A, ILE237D, ILE241A, ILE241D, ILE273A, ILE273D, ILE300A, ILE300D, LEU169A, LEU169D, LEU188A, LEU188D, LEU196A, LEU196D, LEU230A, LEU230D, LEU238A, LEU238D, LEU299A, LEU299D, LEU301A, LEU301D, LYS173A, LYS173D, LYS203A, LYS203D, LYS221A, LYS221D, LYS244A, LYS244D, LYS278A, LYS278D, PHE189A, PHE189D, PHE226A, PHE226D, PRO198A, PRO198D, PRO208A, PRO208D, PRO228A, PRO228D, PRO232A, PRO232D, PRO275A, PRO275D, PRO339A, PRO339D, SER174A, SER174D, SER190A, SER190D, SER195A, SER195D, SER239A, SER239D, SER276A, SER276D, SER303A, SER303D, THR167A, THR167D, THR227A, THR227D, THR234A, THR234D, THR240A, THR240D, THR277A, THR277D, THR296A, THR296D, THR298A, THR298D, TRP109A, TRP109D, TRP279A, TRP279D, TYR199A, TYR199D, TYR242A, TYR242D, TYR274A, TYR274D, TYR281A, TYR281D, TYR338A, TYR338D, VAL170A, VAL170D, VAL176A, VAL176D, VAL185D, VAL192A, VAL192D, VAL201A, VAL201D, VAL207A, VAL207D, VAL222A, VAL222D, VAL224A, VAL224D, VAL225A, VAL225D, VAL231A, VAL231D, VAL243A, VAL243D
• B-C: ALA172B, ALA172C, ALA202B, ALA202C, ALA304B, ALA304C, ARG197B, ARG197C, ARG235B, ARG235C, ARG295B, ARG295C, ASN193B, ASN193C, ASN200B, ASN200C, ASN223B, ASN223C, ASN297B, ASN297C, ASP171B, ASP171C, ASP186B, ASP186C, CYS280B, CYS280C, GLN291B, GLN291C, GLU166B, GLU166C, GLU191B, GLU191C, GLU194B, GLU194C, GLU211B, GLU211C, GLU293B, GLU293C, GLU294B, GLU294C, GLY175B, GLY175C, GLY236B, GLY236C, GLY272B, GLY272C, GLY289B, GLY289C, HIS204B, HIS204C, HIS229B, HIS229C, ILE168B, ILE168C, ILE237B, ILE237C, ILE241B, ILE241C, ILE273B, ILE273C, ILE300B, ILE300C, LEU169B, LEU169C, LEU188B, LEU188C, LEU196B, LEU196C, LEU230B, LEU230C, LEU238B, LEU238C, LEU269B, LEU269C, LEU299B, LEU299C, LEU301B, LEU301C, LYS173B, LYS173C, LYS203B, LYS203C, LYS221B, LYS221C, LYS244B, LYS244C, LYS278B, LYS278C, PHE189B, PHE189C, PHE226B, PHE226C, PRO198B, PRO198C, PRO208B, PRO208C, PRO228B, PRO228C, PRO232B, PRO232C, PRO275B, PRO275C, PRO339B, PRO339C, SER174B, SER174C, SER190B, SER190C, SER195B, SER195C, SER239B, SER239C, SER276B, SER276C, SER303B, SER303C, THR167B, THR167C, THR227B, THR227C, THR234B, THR234C, THR240B, THR240C, THR277B, THR277C, THR296B, THR296C, THR298B, THR298C, TRP109B, TRP109C, TRP279B, TRP279C, TYR199B, TYR199C, TYR242B, TYR242C, TYR274B, TYR274C, TYR281B, TYR281C, TYR338B, TYR338C, VAL170B, VAL170C, VAL176B, VAL176C, VAL192B, VAL192C, VAL201B, VAL201C, VAL207B, VAL207C, VAL222B, VAL222C, VAL224B, VAL224C, VAL225B, VAL225C, VAL231B, VAL231C, VAL243B, VAL243C
• B-D: ARG181B, ARG19B, ARG19D, ARG235B, ARG235D, ASN193B, ASN193D, ASN23B, ASN23D, ASN284B, ASN284D, ASN307B, ASN307D, ASP306B, ASP306D, CYS280B, CYS280D, GLU16B, GLU16D, GLU194B, GLU194D, GLU333B, GLU333D, GLU43B, GLU43D, GLU44B, GLU44D, GLU51B, GLU51D, GLY11B, GLY11D, GLY180B, GLY282B, GLY282D, GLY331B, GLY331D, HIS267B, HIS267D, HIS285B, HIS285D, ILE273B, ILE273D, ILE337B, ILE337D, ILE45B, ILE45D, LEU15B, LEU15D, LEU20B, LEU20D, LEU269B, LEU269D, LEU308B, LEU308D, LEU50B, LEU50D, LYS22B, LYS22D, LYS278B, LYS278D, LYS40B, LYS41B, PHE189B, PHE189D, PHE265B, PHE265D, PHE287B, PHE287D, PHE334B, PHE334D, PHE46B, PHE46D, PRO232B, PRO232D, PRO264B, PRO264D, PRO270B, PRO270D, PRO275B, PRO275D, PRO336B, PRO336D, PRO339B, PRO339D, PRO47B, PRO47D, SER177B, SER177D, SER190D, SER276B, SER276D, SER283B, SER283D, SER48B, SER48D, THR13B, THR13D, THR234B, THR234D, THR335B, THR335D, THR49B, THR49D, TRP279B, TRP279D, TYR12B, TYR12D, TYR274B, TYR274D, TYR281B, TYR281D, TYR338B, TYR338D, VAL176B, VAL176D, VAL18B, VAL18D, VAL266B, VAL266D, VAL286B, VAL286D, VAL309B, VAL309D
• C-D: ALA179C, ARG235C, ARG235D, ASN193C, ASN193D, ASN307C, ASN307D, ASP186C, ASP186D, GLU183C, GLU183D, GLU191C, GLU191D, GLU194C, GLU194D, GLY175C, GLY175D, GLY178C, GLY178D, ILE45C, ILE45D, LEU15C, LEU15D, LEU188C, LEU188D, LEU230C, LEU230D, LEU308C, LEU308D, LYS184C, LYS184D, LYS278C, LYS278D, PHE189C, PHE189D, PHE46C, PHE46D, PRO232C, PRO232D, PRO339C, PRO339D, SER177C, SER177D, SER190C, SER190D, SER195C, SER195D, THR234C, THR234D, THR36C, TYR12C, TYR12D, TYR187C, TYR187D, TYR281C, TYR281D, TYR37C, TYR37D, VAL176C, VAL176D, VAL185C, VAL185D, VAL192C, VAL192D, VAL231C, VAL231D