1VG9

the crystal structures of the rep-1 protein in complex with c-terminally truncated rab7 protein

• Total interactions analyzed: 28
• Total true interactions: 10
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 107
  • Norm. En. per Res.: -3.7264
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-59.6079	-86.8803	-257.576	-404.0641	110	12	3	9810	4	25	21
A-C	-43.404	8.8952	-259.635	-294.1437	122	9	13	11336	3	39	42
A-D	0.0	0.0	-33.8503	-33.8503	32	0	3	1820	0	2	4
B-C	0.0	0.0	-0.0044	-0.0044	3	0	0	7	0	2	0
C-D	-48.1277	-77.3882	-244.912	-370.4279	114	11	4	9511	3	29	23
E-F	-67.9795	-81.5285	-249.214	-398.7219	107	14	3	9378	4	23	21
E-G	-57.691	2.3059	-251.682	-307.0671	124	9	12	11177	3	36	42
E-H	-28.3917	0.0	-38.5599	-66.9516	35	2	2	1861	0	4	4
F-G	0.0	0.0	-0.0076	-0.0076	4	0	0	8	0	2	0
G-H	-59.5424	-76.1526	-249.419	-385.1139	112	14	4	9588	3	29	22

Interface residues

• A-B: ALA110B, ALA252A, ALA2A, ALA389A, ALA43B, ALA48A, ALA65B, ALA76B, ALA81B, ARG113B, ARG222A, ARG223A, ARG250A, ARG386A, ARG398A, ARG69B, ARG79B, ASN225A, ASN247A, ASN4A, ASP114B, ASP16B, ASP227A, ASP38A, ASP3A, ASP44B, ASP63B, CYS383A, CYS385A, CYS388A, CYS396A, GLN109B, GLN176B, GLN382A, GLN60B, GLN67B, GLN71B, GLU105B, GLU220A, GLU253A, GLU379A, GLU68B, GLY18B, GLY221A, GLY376A, GLY378A, GLY392A, GLY393A, GLY42B, GLY66B, GLY74B, GLY80B, HIS36A, HIS399A, ILE108B, ILE12B, ILE226A, ILE394A, ILE41B, ILE61B, LEU107B, LEU35A, LEU374A, LEU380A, LEU397A, LEU46B, LEU5A, LEU73B, LEU8B, LYS10B, MET25B, MET387A, MET494A, PHE224A, PHE384A, PHE391A, PHE420A, PHE45B, PHE50A, PHE70B, PHE77B, PHE9A, PRO112B, PRO115B, PRO381A, PRO605A, PRO6A, SER111B, SER17B, SER249A, SER41A, SER49A, SER51A, SER53A, SER72B, THR16A, THR47B, THR495A, THR64B, TRP62B, TYR251A, TYR375A, TYR395A, TYR42A, TYR43A, TYR78B, VAL248A, VAL37A, VAL390A, VAL75B
• A-C: ALA252A, ALA252C, ALA604A, ALA604C, ARG236A, ARG250A, ARG250C, ARG29C, ARG33C, ARG364A, ARG364C, ASN247A, ASN247C, ASN256A, ASN256C, ASN598A, ASN598C, ASN607A, ASN607C, ASP10C, ASP241A, ASP241C, ASP600A, ASP600C, ASP610A, ASP610C, ASP614A, ASP614C, ASP8C, GLN32C, GLN360A, GLN593A, GLN593C, GLU253A, GLU253C, GLU301A, GLU303A, GLU304A, GLU589A, GLU589C, GLU599A, GLU599C, GLU609A, GLU609C, GLY237A, GLY31C, GLY366A, GLY366C, GLY615C, HIS305A, ILE240A, ILE240C, ILE244A, ILE244C, ILE257A, ILE257C, ILE425C, ILE611A, ILE611C, LEU233A, LEU233C, LEU239A, LEU239C, LEU242A, LEU243A, LEU243C, LEU371A, LEU371C, LEU374A, LEU374C, LEU613A, LEU613C, LYS245A, LYS245C, LYS255A, LYS255C, LYS356A, LYS427C, MET494A, MET494C, PHE254A, PHE254C, PHE370A, PHE370C, PHE372A, PHE372C, PHE391C, PHE601A, PHE601C, PHE9C, PRO306A, PRO373A, PRO373C, PRO603A, PRO603C, PRO605A, PRO605C, PRO606A, PRO606C, PRO608A, PRO608C, PRO6C, SER235A, SER235C, SER249A, SER249C, SER492A, SER492C, THR493A, THR493C, TYR234A, TYR234C, TYR251C, TYR302A, TYR309A, TYR365A, TYR365C, VAL248A, VAL248C, VAL469C, VAL612A, VAL612C
• A-D: ALA276A, ARG236A, ARG275A, ARG364A, ASN256A, ASN35D, ASN367A, ASP277A, CYS273A, CYS361A, GLN360A, GLN36D, GLU301A, GLY363A, GLY366A, GLY42D, ILE41D, LEU296A, LEU359A, LEU362A, LYS157D, LYS32D, MET293A, PHE279A, PHE298A, PHE33D, SER274A, SER34D, THR297A, TYR365A, TYR37D, VAL300A
• B-C: GLN60B, LEU8B, VAL612C
• C-D: ALA110D, ALA252C, ALA389C, ALA43D, ALA48C, ALA65D, ALA76D, ALA81D, ARG113D, ARG222C, ARG223C, ARG250C, ARG386C, ARG398C, ARG69D, ARG79D, ASN225C, ASN247C, ASN30D, ASN4C, ASN607C, ASP16D, ASP227C, ASP38C, ASP3C, ASP44D, ASP63D, CYS383C, CYS385C, CYS388C, CYS396C, GLN109D, GLN382C, GLN60D, GLN67D, GLN71D, GLU105D, GLU253C, GLU379C, GLU609C, GLU68D, GLY18D, GLY221C, GLY376C, GLY378C, GLY392C, GLY393C, GLY42D, GLY66D, GLY74D, GLY80D, HIS36C, HIS399C, ILE108D, ILE12D, ILE226C, ILE394C, ILE41D, ILE61D, LEU107D, LEU35C, LEU374C, LEU380C, LEU397C, LEU46D, LEU5C, LEU613C, LEU73D, LEU8D, LYS10D, LYS32D, MET25D, MET387C, MET494C, PHE224C, PHE384C, PHE391C, PHE420C, PHE45D, PHE50C, PHE70D, PHE77D, PHE9C, PRO112D, PRO381C, PRO605C, PRO606C, PRO608C, PRO6C, SER111D, SER17D, SER41C, SER49C, SER51C, SER53C, SER72D, THR16C, THR47D, THR495C, THR64D, TRP102D, TRP62D, TYR251C, TYR375C, TYR395C, TYR42C, TYR43C, TYR78D, VAL248C, VAL29D, VAL34C, VAL37C, VAL390C, VAL75D
• E-F: ALA110F, ALA252E, ALA389E, ALA43F, ALA48E, ALA65F, ALA76F, ALA81F, ARG113F, ARG222E, ARG223E, ARG250E, ARG386E, ARG398E, ARG40E, ARG69F, ARG79F, ASN225E, ASN247E, ASN4E, ASP114F, ASP227E, ASP38E, ASP3E, ASP44F, ASP63F, CYS383E, CYS385E, CYS388E, CYS396E, GLN109F, GLN382E, GLN60F, GLN67F, GLN71F, GLU105F, GLU220E, GLU253E, GLU379E, GLU68F, GLY221E, GLY376E, GLY378E, GLY392E, GLY393E, GLY42F, GLY66F, GLY74F, GLY80F, HIS36E, HIS399E, ILE108F, ILE12F, ILE226E, ILE394E, ILE41F, ILE61F, LEU107F, LEU35E, LEU374E, LEU380E, LEU397E, LEU46F, LEU5E, LEU73F, LEU8F, LYS10F, MET25F, MET387E, MET494E, PHE106F, PHE224E, PHE384E, PHE391E, PHE420E, PHE45F, PHE50E, PHE70F, PHE77F, PHE9E, PRO112F, PRO115F, PRO381E, PRO605E, PRO6E, SER111F, SER17F, SER249E, SER41E, SER49E, SER51E, SER53E, SER72F, THR16E, THR495E, THR64F, TRP62F, TYR251E, TYR375E, TYR395E, TYR42E, TYR43E, TYR78F, VAL248E, VAL37E, VAL390E, VAL75F
• E-G: ALA252E, ALA252G, ALA604E, ALA604G, ARG236E, ARG250E, ARG250G, ARG29G, ARG33G, ARG364E, ARG364G, ASN247E, ASN247G, ASN256E, ASN256G, ASN598E, ASN598G, ASN607E, ASN607G, ASP10G, ASP241E, ASP241G, ASP600E, ASP600G, ASP610E, ASP610G, ASP614E, ASP614G, ASP8G, CYS490G, GLN32G, GLN360E, GLN467G, GLN593E, GLN593G, GLU253E, GLU253G, GLU301E, GLU303E, GLU304E, GLU589E, GLU589G, GLU599E, GLU599G, GLU609E, GLU609G, GLY237E, GLY31G, GLY366E, GLY366G, GLY615G, HIS305E, ILE240E, ILE240G, ILE244E, ILE244G, ILE257E, ILE257G, ILE425G, ILE611E, ILE611G, LEU233E, LEU233G, LEU239E, LEU239G, LEU242E, LEU243E, LEU243G, LEU371E, LEU371G, LEU374E, LEU374G, LEU613E, LEU613G, LYS245E, LYS245G, LYS255E, LYS255G, LYS356E, LYS427G, MET494E, MET494G, PHE254E, PHE254G, PHE370E, PHE370G, PHE372E, PHE372G, PHE391G, PHE601E, PHE601G, PHE9G, PRO306E, PRO373E, PRO373G, PRO603E, PRO603G, PRO605G, PRO606E, PRO606G, PRO608E, PRO608G, PRO6G, SER235E, SER235G, SER249E, SER249G, SER492E, SER492G, THR493E, THR493G, TYR234E, TYR251E, TYR251G, TYR302E, TYR309E, TYR365E, TYR365G, VAL248E, VAL248G, VAL300E, VAL469G, VAL612E, VAL612G
• E-H: ALA276E, ARG236E, ARG275E, ARG364E, ASN256E, ASN35H, ASN367E, CYS273E, CYS361E, GLN360E, GLN36H, GLN60H, GLU301E, GLY363E, GLY366E, GLY42H, ILE41H, LEU296E, LEU359E, LEU362E, LYS157H, LYS32H, MET293E, PHE279E, PHE298E, PHE33H, PHE358E, PRO369E, SER274E, SER34H, THR297E, TYR365E, TYR37H, VAL300E, VAL612E
• F-G: GLN60F, GLY615G, LEU8F, VAL612G
• G-H: ALA110H, ALA252G, ALA389G, ALA43H, ALA48G, ALA65H, ALA76H, ARG113H, ARG222G, ARG223G, ARG250G, ARG386G, ARG398G, ARG69H, ARG79H, ASN225G, ASN247G, ASN30H, ASN4G, ASN607G, ASP16H, ASP227G, ASP38G, ASP3G, ASP44H, ASP63H, CYS383G, CYS385G, CYS388G, CYS396G, GLN109H, GLN382G, GLN60H, GLN67H, GLN71H, GLU105H, GLU253G, GLU379G, GLU609G, GLU68H, GLY18H, GLY221G, GLY376G, GLY378G, GLY392G, GLY393G, GLY42H, GLY66H, GLY74H, GLY80H, HIS36G, HIS399G, ILE108H, ILE12H, ILE226G, ILE394G, ILE41H, ILE61H, LEU107H, LEU35G, LEU374G, LEU380G, LEU397G, LEU46H, LEU5G, LEU613G, LEU73H, LEU8H, LYS10H, LYS32H, MET25H, MET387G, MET494G, PHE224G, PHE384G, PHE391G, PHE45H, PHE50G, PHE70H, PHE77H, PHE9G, PRO112H, PRO381G, PRO605G, PRO606G, PRO608G, PRO6G, SER111H, SER17H, SER41G, SER49G, SER51G, SER53G, SER72H, THR16G, THR47H, THR495G, THR64H, TRP102H, TRP62H, TYR251G, TYR375G, TYR395G, TYR42G, TYR43G, TYR78H, VAL248G, VAL29H, VAL34G, VAL37G, VAL390G, VAL75H