1VF7

crystal structure of the membrane fusion protein, mexa of the multidrug transporter

• Total interactions analyzed: 78
• Total true interactions: 25
• Strongest Interaction:
  • Chains: C-I
  • Int. Res.: 24
  • Norm. En. per Res.: -4.1982
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-94.5029	-109.2938	-288.168	-491.9647	165	20	7	14417	8	45	31
A-G	-10.8925	0.0	-41.7594	-52.6519	30	1	0	1805	0	2	3
A-H	0.0	24.4844	-15.6424	8.842	17	0	3	966	0	4	2
B-C	-69.4881	-88.6222	-324.468	-482.5784	171	23	6	15606	10	45	33
B-H	-25.9955	-4.7448	-62.107	-92.8473	24	2	0	2479	0	2	1
B-I	0.0	13.5848	-6.3769	7.2079	15	0	3	633	0	4	3
C-D	-57.6054	-99.9808	-296.825	-454.4112	164	22	6	14103	9	43	30
C-I	-25.1635	-5.9723	-69.6201	-100.7559	24	5	0	2812	0	2	2
C-J	0.0	9.7936	-3.6936	6.0999	14	0	3	484	0	4	3
D-E	-48.0017	-50.2707	-290.17	-388.4423	165	23	6	14305	8	41	31
D-J	-25.3348	-6.6094	-74.4944	-106.4386	26	4	0	2896	0	2	2
D-K	0.0	11.1485	-3.0296	8.1189	14	0	2	453	0	4	3
E-F	-52.9545	-58.3058	-270.524	-381.7843	160	23	7	13705	5	43	29
E-K	-22.4288	-6.3539	-71.6917	-100.4744	25	5	0	2859	0	2	2
E-L	0.0	13.2975	-4.5658	8.7317	14	0	3	542	0	4	3
F-G	-63.3425	-93.8293	-246.332	-403.5038	168	23	7	14393	9	40	32
F-L	-21.6124	-5.2099	-63.4324	-90.2547	26	4	0	2711	0	2	2
F-M	0.0	20.6663	-7.4423	13.224	14	0	3	661	0	4	3
G-H	0.0	14.472	-86.7813	-72.3093	62	2	5	3940	0	5	6
G-M	-20.4763	-4.3317	-63.8782	-88.6862	24	3	0	2668	0	2	1
H-I	-51.3503	-61.2031	-262.77	-375.3234	168	21	5	14143	6	42	29
I-J	-53.0675	-91.0557	-286.689	-430.8122	165	20	6	13452	11	41	27
J-K	-43.2688	-60.6635	-261.96	-365.8923	162	12	6	12965	8	39	27
K-L	-45.9292	-80.2289	-300.827	-426.9852	169	20	6	15001	9	42	32
L-M	-21.2666	-70.0939	-270.393	-361.7535	158	14	6	13403	7	43	28

Interface residues

• A-B: ALA112B, ALA116B, ALA117B, ALA123B, ALA124B, ALA128B, ALA154A, ALA161B, ALA163B, ALA183B, ALA192B, ALA37B, ALA41B, ALA64B, ALA74A, ALA78A, ALA83A, ALA85A, ALA88A, ARG129B, ARG133B, ARG144A, ARG147A, ARG186B, ARG188B, ARG189B, ARG221B, ARG239B, ARG34A, ARG34B, ARG39B, ARG44B, ARG54A, ARG96A, ASN115B, ASN131B, ASN158B, ASN162B, ASN202B, ASN244A, ASN246A, ASN247A, ASN36B, ASN48A, ASN86A, ASP113B, ASP176B, ASP212A, ASP230B, ASP61A, ASP72A, ASP79A, GLN109B, GLN110B, GLN120B, GLN127B, GLN160B, GLN168A, GLN168B, GLN179B, GLN215A, GLN46B, GLN81A, GLN84A, GLN93A, GLU126B, GLU152A, GLU211A, GLU223B, GLU226B, GLU231B, GLU248A, GLU42B, GLU58A, GLU77A, GLU92A, GLY143A, GLY146A, GLY153A, GLY159B, GLY213A, GLY232B, GLY234B, GLY252A, GLY49A, GLY59A, GLY65B, ILE130B, ILE141B, ILE145A, ILE238B, ILE40B, ILE50A, ILE51A, LEU100A, LEU119B, LEU138B, LEU155A, LEU170A, LEU184B, LEU185B, LEU210A, LEU249A, LEU250A, LEU52A, LEU55A, LEU68A, LEU87A, LEU99A, LYS108B, LYS122B, LYS53A, LYS57A, MET253A, PHE224B, PHE254A, PHE38B, PHE56A, PRO140B, PRO180B, PRO217A, PRO245A, PRO251A, PRO45B, PRO73A, SER107B, SER148A, SER181B, SER214A, SER225B, SER228B, SER235B, SER60A, SER82A, SER89A, THR151A, THR157B, THR166B, THR178B, THR182B, THR233B, THR237B, THR35A, THR75A, THR90A, TYR111B, TYR118B, TYR134B, TYR174B, TYR216A, TYR69A, TYR76A, TYR97A, VAL101B, VAL106A, VAL150A, VAL156A, VAL167B, VAL177B, VAL227B, VAL229B, VAL236B, VAL241B, VAL255A, VAL43B
• A-G: ALA102A, ALA105A, ALA149G, ALA154G, ALA161G, ARG147G, ARG54G, ASN162G, ASP103A, ASP113A, GLN104A, GLN109A, GLN110A, GLN160G, GLU152G, GLU58G, GLY153G, ILE50G, ILE51G, LEU155G, LYS108A, MET164G, SER107A, SER148G, THR151G, TYR69G, VAL101A, VAL106A, VAL150G, VAL156G
• A-H: ALA102A, ALA102H, ALA105A, ALA105H, ARG96A, ARG96H, ASP103A, ASP103H, GLN104A, GLN104H, LEU100A, LEU100H, LEU99A, LEU99H, TYR97A, VAL106A, VAL106H
• B-C: ALA112C, ALA116C, ALA117C, ALA123C, ALA124C, ALA128C, ALA154B, ALA161C, ALA163C, ALA183C, ALA37B, ALA37C, ALA41C, ALA64C, ALA74B, ALA78B, ALA83B, ALA85B, ALA88B, ARG129C, ARG133C, ARG144B, ARG147B, ARG186C, ARG188C, ARG189C, ARG221C, ARG239C, ARG34B, ARG34C, ARG39C, ARG44C, ARG54B, ARG96B, ASN115C, ASN131C, ASN158C, ASN162C, ASN202C, ASN244B, ASN246B, ASN247B, ASN36B, ASN36C, ASN48B, ASN86B, ASP113C, ASP176B, ASP176C, ASP212B, ASP230C, ASP61B, ASP72B, ASP79B, GLN109C, GLN110C, GLN120C, GLN127C, GLN160C, GLN168B, GLN168C, GLN179C, GLN215B, GLN46C, GLN81B, GLN84B, GLN93B, GLU126C, GLU152B, GLU211B, GLU223C, GLU226C, GLU231C, GLU248B, GLU42C, GLU58B, GLU77B, GLU92B, GLY146B, GLY153B, GLY159C, GLY213B, GLY232C, GLY234C, GLY252B, GLY49B, GLY59B, ILE130C, ILE141C, ILE145B, ILE173B, ILE238C, ILE40B, ILE40C, ILE50B, ILE51B, LEU100B, LEU119C, LEU138C, LEU155B, LEU170B, LEU184C, LEU185C, LEU210B, LEU249B, LEU250B, LEU52B, LEU55B, LEU87B, LEU99B, LYS108C, LYS122C, LYS53B, LYS57B, MET164C, MET253B, PHE224C, PHE254B, PHE38C, PHE56B, PRO140C, PRO180C, PRO217B, PRO245B, PRO251B, PRO45C, PRO73B, SER107C, SER148B, SER181C, SER214B, SER225C, SER228C, SER235C, SER60B, SER82B, SER89B, THR151B, THR157B, THR157C, THR166C, THR178C, THR182C, THR233C, THR237C, THR35B, THR75B, THR90B, TYR111C, TYR118C, TYR134C, TYR174C, TYR216B, TYR69B, TYR76B, TYR97B, VAL101C, VAL106B, VAL125C, VAL150B, VAL156B, VAL167C, VAL175B, VAL175C, VAL177C, VAL227C, VAL229C, VAL236C, VAL241C, VAL255B, VAL43C
• B-H: ALA102B, ALA102H, ALA105B, ALA105H, ASP103B, ASP103H, GLN104B, GLN104H, GLN109B, GLN109H, GLN110B, GLN110H, LEU100B, LEU100H, LYS108B, LYS108H, SER107B, SER107H, TYR111B, TYR111H, VAL101B, VAL101H, VAL106B, VAL106H
• B-I: ALA105B, ALA105I, ARG96B, ARG96I, ASP103B, ASP103I, GLN104B, GLN104I, LEU100B, LEU100I, LEU99B, LEU99I, TYR97I, VAL106B, VAL106I
• C-D: ALA112D, ALA116D, ALA117D, ALA123D, ALA124D, ALA128D, ALA149C, ALA154C, ALA161D, ALA163D, ALA183D, ALA41D, ALA64D, ALA74C, ALA78C, ALA83C, ALA85C, ALA88C, ARG129D, ARG133D, ARG144C, ARG147C, ARG186D, ARG188D, ARG189D, ARG221D, ARG239D, ARG34C, ARG34D, ARG39D, ARG44D, ARG54C, ARG96C, ASN115D, ASN131D, ASN158D, ASN162D, ASN202D, ASN244C, ASN246C, ASN247C, ASN36C, ASN36D, ASN48C, ASN86C, ASP113D, ASP176D, ASP212C, ASP230D, ASP72C, ASP79C, GLN109D, GLN110D, GLN120D, GLN127D, GLN160D, GLN168C, GLN168D, GLN215C, GLN46D, GLN81C, GLN84C, GLN93C, GLU126D, GLU152C, GLU211C, GLU223D, GLU226D, GLU231D, GLU248C, GLU42D, GLU58C, GLU77C, GLU92C, GLY146C, GLY153C, GLY159D, GLY213C, GLY232D, GLY234D, GLY252C, GLY49C, GLY59C, ILE130D, ILE141D, ILE145C, ILE173C, ILE238D, ILE40C, ILE40D, ILE50C, ILE51C, ILE71C, LEU100C, LEU119D, LEU138D, LEU155C, LEU170C, LEU184D, LEU185D, LEU210C, LEU249C, LEU250C, LEU52C, LEU55C, LEU87C, LEU99C, LYS108D, LYS122D, LYS53C, LYS57C, MET253C, PHE224D, PHE254C, PHE38D, PRO140D, PRO180D, PRO217C, PRO245C, PRO251C, PRO45D, PRO73C, SER107D, SER148C, SER181D, SER214C, SER225D, SER228D, SER235D, SER60C, SER82C, SER89C, THR151C, THR157C, THR157D, THR166D, THR178D, THR182D, THR233D, THR237D, THR35C, THR75C, THR90C, TYR111D, TYR118D, TYR134D, TYR174D, TYR216C, TYR76C, TYR97C, VAL101D, VAL106C, VAL125D, VAL150C, VAL156C, VAL167D, VAL175D, VAL177D, VAL227D, VAL229D, VAL236D, VAL241D, VAL255C, VAL43D
• C-I: ALA102C, ALA102I, ALA105C, ALA105I, ASP103C, ASP103I, GLN104C, GLN104I, GLN109C, GLN109I, GLN110C, GLN110I, LEU100C, LEU100I, LYS108C, LYS108I, SER107C, SER107I, TYR111C, TYR111I, VAL101C, VAL101I, VAL106C, VAL106I
• C-J: ALA105C, ALA105J, ARG96C, ARG96J, ASP103C, ASP103J, GLN104C, GLN104J, LEU100C, LEU100J, LEU99C, LEU99J, VAL106C, VAL106J
• D-E: ALA112E, ALA116E, ALA117E, ALA123E, ALA124E, ALA128E, ALA154D, ALA161E, ALA163E, ALA183E, ALA37E, ALA41E, ALA64E, ALA74D, ALA78D, ALA83D, ALA85D, ALA88D, ARG129E, ARG133E, ARG144D, ARG147D, ARG186E, ARG188E, ARG189E, ARG221E, ARG239E, ARG34D, ARG34E, ARG39E, ARG44E, ARG54D, ARG96D, ASN115E, ASN131E, ASN158E, ASN162E, ASN202E, ASN244D, ASN246D, ASN247D, ASN36E, ASN48D, ASN86D, ASP113E, ASP176E, ASP212D, ASP230E, ASP61D, ASP72D, ASP79D, GLN109E, GLN110E, GLN120E, GLN127E, GLN160E, GLN168D, GLN168E, GLN179E, GLN215D, GLN46E, GLN81D, GLN84D, GLN93D, GLU126E, GLU152D, GLU211D, GLU223E, GLU226E, GLU231E, GLU248D, GLU42E, GLU58D, GLU77D, GLU92D, GLY146D, GLY153D, GLY159E, GLY213D, GLY232E, GLY234E, GLY252D, GLY49D, GLY59D, ILE130E, ILE141E, ILE145D, ILE173D, ILE238E, ILE40E, ILE50D, ILE51D, ILE71D, LEU100D, LEU119E, LEU138E, LEU155D, LEU170D, LEU184E, LEU185E, LEU210D, LEU249D, LEU250D, LEU52D, LEU55D, LEU87D, LEU99D, LYS108E, LYS122E, LYS53D, LYS57D, MET253D, PHE224E, PHE254D, PHE38E, PHE56D, PRO140E, PRO180E, PRO217D, PRO245D, PRO251D, PRO45E, PRO73D, SER107E, SER148D, SER181E, SER214D, SER225E, SER228E, SER235E, SER60D, SER82D, SER89D, THR151D, THR157D, THR157E, THR166E, THR178E, THR182E, THR233E, THR237E, THR35D, THR75D, THR90D, TYR111E, TYR118E, TYR134E, TYR174E, TYR216D, TYR69D, TYR76D, TYR97D, VAL106D, VAL125E, VAL150D, VAL156D, VAL167E, VAL175E, VAL177E, VAL227E, VAL229E, VAL236E, VAL241E, VAL255D, VAL43E
• D-J: ALA102D, ALA102J, ALA105D, ALA105J, ASP103D, ASP103J, GLN104D, GLN104J, GLN109D, GLN109J, GLN110D, GLN110J, LEU100D, LEU100J, LYS108D, LYS108J, LYS98D, LYS98J, SER107D, SER107J, TYR111D, TYR111J, VAL101D, VAL101J, VAL106D, VAL106J
• D-K: ALA105D, ALA105K, ARG96D, ARG96K, ASP103D, ASP103K, GLN104D, GLN104K, LEU100D, LEU100K, LEU99D, LEU99K, VAL106D, VAL106K
• E-F: ALA112F, ALA116F, ALA117F, ALA123F, ALA124F, ALA128F, ALA154E, ALA161F, ALA163F, ALA183F, ALA37F, ALA41F, ALA64F, ALA74E, ALA78E, ALA83E, ALA85E, ALA88E, ARG129F, ARG133F, ARG144E, ARG147E, ARG186F, ARG188F, ARG189F, ARG221F, ARG239F, ARG34E, ARG39F, ARG44F, ARG54E, ARG96E, ASN115F, ASN131F, ASN158F, ASN162F, ASN202F, ASN244E, ASN246E, ASN247E, ASN36F, ASN48E, ASN86E, ASP113F, ASP176F, ASP212E, ASP230F, ASP61E, ASP72E, ASP79E, GLN109F, GLN110F, GLN120F, GLN127F, GLN160F, GLN168E, GLN168F, GLN215E, GLN46F, GLN81E, GLN84E, GLN93E, GLN95E, GLU126F, GLU152E, GLU211E, GLU223F, GLU226F, GLU231F, GLU248E, GLU42F, GLU58E, GLU77E, GLU92E, GLY146E, GLY153E, GLY159F, GLY213E, GLY232F, GLY234F, GLY252E, GLY49E, GLY59E, ILE130F, ILE141F, ILE145E, ILE173E, ILE238F, ILE40F, ILE50E, ILE51E, ILE71E, LEU100E, LEU119F, LEU138F, LEU155E, LEU170E, LEU184F, LEU185F, LEU210E, LEU249E, LEU250E, LEU52E, LEU55E, LEU87E, LEU99E, LYS108F, LYS122F, LYS53E, LYS57E, MET253E, PHE224F, PHE254E, PHE38F, PHE56E, PRO140F, PRO180F, PRO251E, PRO45F, PRO73E, SER107F, SER139F, SER148E, SER181F, SER214E, SER225F, SER228F, SER235F, SER60E, SER82E, SER89E, THR151E, THR157F, THR166F, THR178F, THR182F, THR233F, THR237F, THR35E, THR75E, THR90E, TYR111F, TYR118F, TYR134F, TYR174F, TYR216E, TYR69E, TYR76E, TYR97E, VAL106E, VAL150E, VAL156E, VAL167F, VAL177F, VAL227F, VAL229F, VAL236F, VAL241F, VAL255E, VAL43F
• E-K: ALA102E, ALA102K, ALA105E, ALA105K, ASP103E, ASP103K, GLN104E, GLN104K, GLN109E, GLN109K, GLN110E, GLN110K, LEU100E, LEU100K, LYS108E, LYS108K, LYS98E, SER107E, SER107K, TYR111E, TYR111K, VAL101E, VAL101K, VAL106E, VAL106K
• E-L: ALA105E, ALA105L, ARG96E, ARG96L, ASP103E, ASP103L, GLN104E, GLN104L, LEU100E, LEU100L, LEU99E, LEU99L, VAL106E, VAL106L
• F-G: ALA112G, ALA116G, ALA117G, ALA123G, ALA124G, ALA128G, ALA154F, ALA161G, ALA163G, ALA165G, ALA183G, ALA203G, ALA37G, ALA41G, ALA64G, ALA74F, ALA78F, ALA83F, ALA85F, ALA88F, ARG129G, ARG133G, ARG144F, ARG147F, ARG186G, ARG188G, ARG189G, ARG221G, ARG239G, ARG34F, ARG34G, ARG39G, ARG44G, ARG54F, ARG96F, ASN115G, ASN131G, ASN158G, ASN162G, ASN202G, ASN244F, ASN246F, ASN247F, ASN36G, ASN48F, ASN86F, ASP113G, ASP176G, ASP201G, ASP212F, ASP230G, ASP61F, ASP72F, ASP79F, GLN109G, GLN110F, GLN110G, GLN120G, GLN127G, GLN160G, GLN168F, GLN168G, GLN179G, GLN215F, GLN46G, GLN81F, GLN84F, GLN93F, GLU126G, GLU152F, GLU211F, GLU223G, GLU226G, GLU231G, GLU248F, GLU42G, GLU58F, GLU77F, GLU92F, GLY146F, GLY153F, GLY159G, GLY213F, GLY232G, GLY234G, GLY252F, GLY49F, GLY59F, GLY65G, ILE130G, ILE141G, ILE145F, ILE238G, ILE40G, ILE50F, ILE51F, LEU100F, LEU119G, LEU138G, LEU155F, LEU170F, LEU184G, LEU185G, LEU210F, LEU249F, LEU250F, LEU52F, LEU55F, LEU87F, LEU99F, LYS108G, LYS122G, LYS53F, LYS57F, MET253F, PHE224G, PHE254F, PHE38G, PHE56F, PRO140G, PRO180G, PRO217F, PRO245F, PRO251F, PRO45G, PRO73F, SER107G, SER121G, SER139G, SER148F, SER181G, SER214F, SER225G, SER228G, SER235G, SER60F, SER82F, SER89F, THR151F, THR157G, THR166G, THR178G, THR182G, THR233G, THR237G, THR35F, THR75F, THR90F, TYR111G, TYR118G, TYR134G, TYR174G, TYR216F, TYR76F, TYR80F, TYR97F, VAL106F, VAL125G, VAL150F, VAL167G, VAL175G, VAL177G, VAL227G, VAL229G, VAL236G, VAL241G, VAL255F, VAL43G
• F-L: ALA102F, ALA102L, ALA105F, ALA105L, ASP103F, ASP103L, GLN104F, GLN104L, GLN109F, GLN109L, GLN110F, GLN110L, LEU100F, LEU100L, LEU99L, LYS108F, LYS108L, LYS98L, SER107F, SER107L, TYR111F, TYR111L, VAL101F, VAL101L, VAL106F, VAL106L
• F-M: ALA105F, ALA105M, ARG96F, ARG96M, ASP103F, ASP103M, GLN104F, GLN104M, LEU100F, LEU100M, LEU99F, LEU99M, VAL106F, VAL106M
• G-H: ALA74G, ALA74H, ALA78G, ALA78H, ALA83G, ALA83H, ALA85G, ALA85H, ALA88G, ALA88H, ARG96G, ARG96H, ASN48G, ASN86G, ASN86H, ASP72G, ASP72H, ASP79G, ASP79H, GLN81G, GLN81H, GLN84G, GLN84H, GLN91G, GLN91H, GLN93G, GLN93H, GLN95H, GLU77G, GLU77H, GLU92G, GLU92H, GLY153G, GLY153H, GLY49G, ILE50G, ILE50H, ILE71G, LEU100H, LEU155G, LEU52G, LEU52H, LEU87G, LEU87H, LEU99H, PRO73G, PRO73H, SER121G, SER82G, SER82H, SER89G, SER89H, THR75G, THR75H, THR90G, THR90H, TYR76G, TYR76H, TYR80G, TYR80H, TYR97G, TYR97H
• G-M: ALA102G, ALA102M, ALA105G, ALA105M, ASP103G, ASP103M, GLN104G, GLN104M, GLN109G, GLN109M, GLN110G, GLN110M, LEU100G, LEU100M, LYS108G, LYS108M, SER107G, SER107M, TYR111G, TYR111M, VAL101G, VAL101M, VAL106G, VAL106M
• H-I: ALA112H, ALA114I, ALA116H, ALA117H, ALA123H, ALA124H, ALA128H, ALA154I, ALA161H, ALA163H, ALA183H, ALA203H, ALA37H, ALA41H, ALA64H, ALA74I, ALA78I, ALA83I, ALA85I, ALA88I, ARG129H, ARG133H, ARG144I, ARG147I, ARG186H, ARG188H, ARG189H, ARG221H, ARG239H, ARG34H, ARG34I, ARG39H, ARG44H, ARG54I, ARG96I, ASN115H, ASN131H, ASN158H, ASN162H, ASN202H, ASN244I, ASN246I, ASN247I, ASN36H, ASN36I, ASN48I, ASN86I, ASP113H, ASP176H, ASP201H, ASP212I, ASP230H, ASP61I, ASP72I, ASP79I, GLN109H, GLN110H, GLN120H, GLN127H, GLN160H, GLN168H, GLN168I, GLN179H, GLN215I, GLN46H, GLN81I, GLN84I, GLN93I, GLU126H, GLU152I, GLU211I, GLU223H, GLU226H, GLU231H, GLU248I, GLU42H, GLU58I, GLU77I, GLU92I, GLY146I, GLY153I, GLY159H, GLY213I, GLY232H, GLY234H, GLY252I, GLY49I, GLY59I, ILE130H, ILE141H, ILE145I, ILE173I, ILE238H, ILE40H, ILE50I, ILE51I, LEU100I, LEU119H, LEU138H, LEU155I, LEU170I, LEU184H, LEU185H, LEU210I, LEU249I, LEU250I, LEU52I, LEU55I, LEU87I, LEU99I, LYS108H, LYS122H, LYS53I, LYS57I, MET253I, PHE224H, PHE254I, PHE38H, PHE56I, PRO140H, PRO180H, PRO217I, PRO245I, PRO251I, PRO45H, PRO73I, SER107H, SER148I, SER181H, SER214I, SER225H, SER228H, SER235H, SER60I, SER82I, SER89I, THR151I, THR157H, THR157I, THR166H, THR178H, THR182H, THR233H, THR237H, THR35I, THR75I, THR90I, TYR111H, TYR118H, TYR134H, TYR174H, TYR216I, TYR76I, TYR97I, VAL101H, VAL106I, VAL125H, VAL150I, VAL156I, VAL167H, VAL175H, VAL177H, VAL227H, VAL229H, VAL236H, VAL241H, VAL255I, VAL43H
• I-J: ALA112I, ALA116I, ALA117I, ALA123I, ALA124I, ALA128I, ALA154J, ALA161I, ALA163I, ALA183I, ALA37I, ALA41I, ALA64I, ALA74J, ALA78J, ALA83J, ALA85J, ALA88J, ARG129I, ARG133I, ARG144J, ARG147J, ARG186I, ARG188I, ARG189I, ARG221I, ARG239I, ARG34I, ARG34J, ARG39I, ARG44I, ARG54J, ARG96J, ASN115I, ASN131I, ASN158I, ASN162I, ASN202I, ASN244J, ASN246J, ASN247J, ASN36I, ASN48J, ASN86J, ASP113I, ASP176I, ASP212J, ASP230I, ASP61J, ASP72J, ASP79J, GLN109I, GLN110I, GLN120I, GLN127I, GLN160I, GLN168I, GLN168J, GLN215J, GLN46I, GLN81J, GLN84J, GLN93J, GLU126I, GLU152J, GLU211J, GLU223I, GLU226I, GLU231I, GLU248J, GLU42I, GLU58J, GLU77J, GLU92J, GLY146J, GLY153J, GLY159I, GLY213J, GLY232I, GLY234I, GLY252J, GLY49J, GLY59J, GLY65I, ILE130I, ILE141I, ILE145J, ILE173J, ILE238I, ILE40I, ILE50J, ILE51J, LEU100J, LEU119I, LEU138I, LEU155J, LEU170J, LEU184I, LEU185I, LEU210J, LEU249J, LEU250J, LEU52J, LEU55J, LEU87J, LEU99J, LYS108I, LYS122I, LYS53J, LYS57J, MET164I, MET253J, PHE224I, PHE254J, PHE38I, PHE56J, PRO140I, PRO180I, PRO217J, PRO251J, PRO45I, PRO73J, SER107I, SER139I, SER148J, SER181I, SER214J, SER225I, SER228I, SER235I, SER60J, SER82J, SER89J, THR151J, THR157I, THR157J, THR166I, THR178I, THR182I, THR233I, THR237I, THR35J, THR75J, THR90J, TYR111I, TYR118I, TYR134I, TYR174I, TYR216J, TYR76J, TYR97J, VAL106J, VAL125I, VAL150J, VAL156J, VAL167I, VAL175I, VAL177I, VAL227I, VAL229I, VAL236I, VAL241I, VAL255J, VAL43I, VAL47I
• J-K: ALA112J, ALA116J, ALA117J, ALA123J, ALA124J, ALA128J, ALA154K, ALA161J, ALA163J, ALA183J, ALA37J, ALA41J, ALA64J, ALA74K, ALA78K, ALA83K, ALA85K, ALA88K, ARG129J, ARG133J, ARG144K, ARG147K, ARG186J, ARG188J, ARG189J, ARG221J, ARG239J, ARG34J, ARG34K, ARG39J, ARG44J, ARG54K, ARG96K, ASN115J, ASN131J, ASN158J, ASN162J, ASN202J, ASN244K, ASN246K, ASN247K, ASN36J, ASN36K, ASN48K, ASN86K, ASP113J, ASP176J, ASP212K, ASP230J, ASP72K, ASP79K, GLN109J, GLN110J, GLN110K, GLN120J, GLN127J, GLN160J, GLN168J, GLN168K, GLN46J, GLN81K, GLN84K, GLN93K, GLU126J, GLU152K, GLU211K, GLU223J, GLU226J, GLU231J, GLU248K, GLU42J, GLU58K, GLU77K, GLU92K, GLY146K, GLY153K, GLY159J, GLY213K, GLY232J, GLY234J, GLY252K, GLY49K, GLY59K, ILE130J, ILE141J, ILE145K, ILE173K, ILE238J, ILE40J, ILE40K, ILE50K, ILE51K, LEU100K, LEU119J, LEU138J, LEU155K, LEU170K, LEU184J, LEU185J, LEU210K, LEU249K, LEU250K, LEU52K, LEU55K, LEU87K, LEU99K, LYS108J, LYS122J, LYS53K, LYS57K, MET253K, PHE224J, PHE254K, PHE38J, PHE56K, PRO140J, PRO180J, PRO251K, PRO45J, PRO73K, SER107J, SER148K, SER181J, SER214K, SER225J, SER228J, SER235J, SER60K, SER82K, SER89K, THR151K, THR157J, THR157K, THR166J, THR178J, THR182J, THR233J, THR237J, THR35K, THR75K, THR90K, TYR111J, TYR118J, TYR134J, TYR174J, TYR216K, TYR76K, TYR97K, VAL101J, VAL106K, VAL125J, VAL150K, VAL156K, VAL167J, VAL175J, VAL177J, VAL227J, VAL229J, VAL236J, VAL241J, VAL43J, VAL47J
• K-L: ALA112K, ALA116K, ALA117K, ALA123K, ALA124K, ALA128K, ALA154L, ALA161K, ALA163K, ALA183K, ALA37K, ALA37L, ALA41K, ALA64K, ALA74L, ALA78L, ALA83L, ALA85L, ALA88L, ARG129K, ARG133K, ARG144L, ARG147L, ARG186K, ARG188K, ARG189K, ARG221K, ARG239K, ARG34L, ARG39K, ARG44K, ARG54L, ARG96L, ASN115K, ASN131K, ASN158K, ASN162K, ASN202K, ASN244L, ASN246L, ASN247L, ASN36K, ASN36L, ASN48L, ASN86L, ASP113K, ASP176K, ASP176L, ASP212L, ASP230K, ASP61L, ASP72L, ASP79L, GLN109K, GLN110K, GLN110L, GLN120K, GLN127K, GLN160K, GLN168K, GLN168L, GLN215L, GLN46K, GLN81L, GLN84L, GLN93L, GLU126K, GLU152L, GLU211L, GLU223K, GLU226K, GLU231K, GLU248L, GLU42K, GLU58L, GLU77L, GLU92L, GLY146L, GLY153L, GLY159K, GLY213L, GLY232K, GLY234K, GLY252L, GLY49L, GLY59L, ILE130K, ILE141K, ILE145L, ILE173L, ILE238K, ILE40K, ILE40L, ILE50L, ILE51L, LEU100L, LEU119K, LEU138K, LEU155L, LEU170L, LEU184K, LEU185K, LEU210L, LEU249L, LEU250L, LEU52L, LEU55L, LEU87L, LEU99L, LYS108K, LYS122K, LYS53L, LYS57L, MET164K, MET253L, PHE224K, PHE254L, PHE38K, PHE56L, PRO140K, PRO180K, PRO217L, PRO245L, PRO251L, PRO45K, PRO73L, SER107K, SER148L, SER181K, SER214L, SER225K, SER228K, SER235K, SER60L, SER82L, SER89L, THR151L, THR157K, THR157L, THR166K, THR178K, THR182K, THR233K, THR237K, THR35L, THR75L, THR90L, TYR111K, TYR118K, TYR134K, TYR174K, TYR216L, TYR76L, TYR97L, VAL101K, VAL106L, VAL125K, VAL150L, VAL156L, VAL167K, VAL175K, VAL177K, VAL227K, VAL229K, VAL236K, VAL241K, VAL255L, VAL43K, VAL47K
• L-M: ALA112L, ALA116L, ALA117L, ALA123L, ALA124L, ALA128L, ALA149M, ALA154M, ALA161L, ALA163L, ALA183L, ALA37L, ALA37M, ALA41L, ALA74M, ALA78M, ALA83M, ALA85M, ALA88M, ARG129L, ARG133L, ARG144M, ARG147M, ARG186L, ARG188L, ARG189L, ARG239L, ARG34L, ARG34M, ARG39L, ARG44L, ARG54M, ARG96M, ASN115L, ASN131L, ASN158L, ASN162L, ASN202L, ASN246M, ASN247M, ASN36L, ASN36M, ASN48M, ASN86M, ASP113L, ASP176L, ASP176M, ASP212M, ASP230L, ASP72M, ASP79M, GLN109L, GLN110L, GLN120L, GLN127L, GLN160L, GLN168L, GLN168M, GLN215M, GLN46L, GLN81M, GLN84M, GLN93M, GLU126L, GLU152M, GLU211M, GLU226L, GLU231L, GLU248M, GLU42L, GLU58M, GLU77M, GLU92M, GLY146M, GLY153M, GLY159L, GLY213M, GLY232L, GLY234L, GLY252M, GLY49M, GLY59M, ILE130L, ILE141L, ILE145M, ILE238L, ILE40L, ILE40M, ILE50M, ILE51M, LEU100M, LEU119L, LEU155M, LEU170M, LEU184L, LEU185L, LEU210M, LEU249M, LEU250M, LEU52M, LEU55M, LEU87M, LEU99M, LYS108L, LYS122L, LYS53M, LYS57M, MET253M, PHE224L, PHE254M, PHE38L, PHE56M, PRO140L, PRO180L, PRO251M, PRO45L, PRO73M, SER107L, SER148M, SER181L, SER214M, SER225L, SER228L, SER235L, SER60M, SER82M, SER89M, THR151M, THR157L, THR157M, THR166L, THR178L, THR182L, THR233L, THR237L, THR35M, THR75M, THR90M, TYR111L, TYR118L, TYR134L, TYR174L, TYR216M, TYR69M, TYR76M, TYR97M, VAL101L, VAL106M, VAL150M, VAL156M, VAL167L, VAL175L, VAL177L, VAL227L, VAL229L, VAL236L, VAL255M, VAL43L