1VCB

the vhl-elonginc-elonginb structure

• Total interactions analyzed: 66
• Total true interactions: 19
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 89
  • Norm. En. per Res.: -4.2665
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-73.0309	-7.4917	-299.199	-379.7216	89	17	6	11646	1	22	20
A-C	0.0	0.0	-0.0029	-0.0029	3	0	0	2	0	1	1
B-C	-41.8354	-58.0508	-235.116	-335.0023	86	11	14	10940	3	11	12
B-K	0.0	0.0	-0.3624	-0.3624	2	0	0	28	0	1	1
C-E	0.0	0.0	-0.0204	-0.0204	5	0	0	14	0	2	2
C-K	0.0	-24.1672	-92.6167	-116.7839	53	14	2	4446	0	9	4
C-L	0.0	0.0	-0.4872	-0.4872	9	0	0	108	0	3	6
D-E	-62.767	-5.7518	-287.301	-355.8198	89	16	5	11370	1	21	20
D-F	0.0	0.0	-0.0028	-0.0028	2	0	0	2	0	1	1
E-F	-45.2472	-58.3052	-250.522	-354.0744	86	16	16	11484	3	11	12
E-H	0.0	0.0	-0.3047	-0.3047	2	0	0	25	0	1	1
F-H	0.0	-25.5026	-81.4069	-106.9095	49	6	2	3895	1	8	4
F-I	0.0	0.0	-0.3074	-0.3074	9	0	0	85	0	3	5
G-H	-67.9788	-18.0949	-305.568	-391.6417	92	18	6	11860	1	23	21
G-I	0.0	0.0	-0.0033	-0.0033	3	0	0	2	0	1	1
H-I	-52.345	-59.8531	-250.884	-363.0821	89	19	16	11441	3	11	12
H-L	0.0	0.0	-0.0309	-0.0309	2	0	0	14	0	1	0
J-K	-68.2678	-17.2134	-296.277	-381.7582	92	16	6	11641	1	23	21
K-L	-46.2862	-59.26	-248.526	-354.0722	89	12	16	11340	3	11	12

Interface residues

• A-B: ALA100B, ALA18A, ALA71A, ALA96B, ARG68A, ARG82B, ARG8A, ARG9A, ASP17A, ASP25B, ASP2A, CYS74B, GLN70A, GLU102B, GLU28B, GLU89B, GLU91A, GLU92B, GLU98A, GLU98B, GLY26B, GLY33A, HIS10A, HIS27B, HIS35B, HIS68B, ILE14A, ILE22B, ILE30A, ILE30B, ILE34A, ILE65B, ILE7A, ILE90A, ILE90B, ILE99B, LEU101B, LEU21B, LEU35A, LEU5A, LEU70B, LYS11A, LYS20B, LYS32B, LYS72B, LYS80B, MET105B, MET17B, MET1A, MET6A, MET75B, PHE15A, PHE29B, PHE4A, PHE77B, PHE93A, PHE93B, PRO66B, PRO69A, PRO72A, PRO91B, PRO92A, PRO94B, PRO96A, PRO97A, PRO97B, SER23B, SER24B, SER64A, SER67B, SER71B, SER94A, SER95A, THR12A, THR13A, THR16A, THR74A, THR78B, THR88B, TYR18B, TYR76B, TYR79B, TYR83B, VAL19B, VAL31A, VAL31B, VAL69B, VAL73B, VAL81B
• A-C: GLU98A, LEU169C, LEU178C
• B-C: ALA100B, ALA106B, ALA107B, ALA96B, ARG161C, ARG167C, ARG177C, ARG79C, ARG82B, ARG82C, ASN108B, ASN131C, ASN150C, ASN78C, ASN85B, ASP111B, ASP179C, ASP187C, CYS112B, CYS162C, CYS74B, GLN132C, GLN164C, GLU102B, GLU160C, GLU89B, GLU92B, GLU98B, GLY104C, ILE151C, ILE180C, ILE90B, ILE95B, ILE99B, LEU101B, LEU103B, LEU104B, LEU110B, LEU128C, LEU129C, LEU153C, LEU158C, LEU163C, LEU169C, LEU178C, LEU184C, LEU188C, LEU70B, LYS159C, LYS72B, LYS80B, MET105B, MET75B, PHE109B, PHE77B, PHE93B, PRO103C, PRO154C, PRO81C, PRO91B, PRO94B, PRO97B, SER168C, SER183C, SER80C, SER86B, SER87B, THR152C, THR157C, THR38B, THR84B, THR88B, TYR156C, TYR175C, TYR185C, TYR76B, TYR79B, TYR83B, VAL155C, VAL165C, VAL166C, VAL170C, VAL181C, VAL69B, VAL73B, VAL81B
• B-K: ARG63K, GLU89B
• C-E: ARG177C, ASN85E, GLU173C, LYS171C, LYS43E
• C-K: ALA106K, ALA107K, ALA149C, ALA44K, ARG107C, ARG108C, ARG63K, ARG79C, ASN108K, ASN131C, ASN150C, ASN61K, ASN78C, ASP111K, ASP143C, CYS112K, CYS77C, GLN145C, GLN73C, GLU59K, GLU64K, GLY104C, GLY106C, GLY144C, GLY40K, GLY48K, HIS110C, ILE109C, ILE147C, ILE42K, ILE65K, ILE75C, LEU101C, LEU110K, LEU46K, LYS43K, MET45K, PHE109K, PHE148C, PHE62K, PHE76C, PRO102C, PRO103C, PRO146C, PRO49K, SER24K, SER39K, SER47K, SER80C, THR105C, THR41K, VAL60K, VAL74C
• C-L: ARG107C, ARG108C, ARG182L, HIS110C, LEU184L, LYS159L, PRO99C, SER183L, VAL181L
• D-E: ALA100E, ALA18D, ALA71D, ALA96E, ARG68D, ARG82E, ARG8D, ARG9D, ASP17D, ASP25E, ASP2D, CYS74E, GLN70D, GLU102E, GLU28E, GLU89E, GLU91D, GLU92E, GLU98D, GLU98E, GLY26E, GLY33D, HIS10D, HIS27E, HIS35E, HIS68E, ILE14D, ILE22E, ILE30D, ILE30E, ILE34D, ILE65E, ILE7D, ILE90D, ILE90E, ILE95E, ILE99E, LEU101E, LEU21E, LEU35D, LEU5D, LEU70E, LYS11D, LYS20E, LYS32E, LYS72E, LYS80E, MET105E, MET17E, MET1D, MET6D, MET75E, PHE15D, PHE29E, PHE4D, PHE77E, PHE93D, PHE93E, PRO66E, PRO69D, PRO72D, PRO91E, PRO92D, PRO94E, PRO96D, PRO97D, PRO97E, SER23E, SER24E, SER64D, SER67E, SER71E, SER94D, SER95D, THR12D, THR13D, THR16D, THR74D, THR78E, THR88E, TYR18E, TYR76E, TYR79E, TYR83E, VAL19E, VAL31E, VAL69E, VAL73E, VAL81E
• D-F: GLU98D, LEU178F
• E-F: ALA100E, ALA106E, ALA107E, ALA96E, ARG161F, ARG167F, ARG177F, ARG79F, ARG82E, ARG82F, ASN108E, ASN131F, ASN150F, ASN78F, ASN85E, ASP111E, ASP179F, ASP187F, CYS112E, CYS162F, CYS74E, GLN132F, GLN164F, GLU102E, GLU160F, GLU89E, GLU92E, GLU98E, GLY104F, ILE151F, ILE180F, ILE90E, ILE95E, ILE99E, LEU101E, LEU103E, LEU104E, LEU110E, LEU128F, LEU129F, LEU153F, LEU158F, LEU163F, LEU169F, LEU178F, LEU184F, LEU188F, LEU70E, LYS159F, LYS72E, LYS80E, MET105E, MET75E, PHE109E, PHE77E, PHE93E, PRO103F, PRO154F, PRO81F, PRO91E, PRO94E, PRO97E, SER168F, SER183F, SER80F, SER86E, SER87E, THR152F, THR157F, THR38E, THR84E, THR88E, TYR156F, TYR175F, TYR185F, TYR76E, TYR79E, TYR83E, VAL155F, VAL165F, VAL166F, VAL170F, VAL181F, VAL69E, VAL73E, VAL81E
• E-H: ARG63H, GLU89E
• F-H: ALA107H, ALA149F, ALA44H, ARG107F, ARG108F, ARG63H, ARG79F, ASN108H, ASN131F, ASN150F, ASN61H, ASN78F, ASP111H, ASP143F, CYS112H, CYS77F, GLN145F, GLN73F, GLU59H, GLU64H, GLY104F, GLY106F, GLY144F, GLY40H, GLY48H, HIS110F, ILE109F, ILE147F, ILE42H, ILE65H, ILE75F, LEU101F, LEU110H, LEU46H, LYS43H, MET45H, PHE109H, PHE148F, PHE62H, PHE76F, PRO102F, PRO103F, PRO146F, PRO49H, SER39H, SER80F, THR105F, THR41H, VAL60H
• F-I: ARG107F, ARG108F, ARG182I, HIS110F, LEU184I, LYS159I, PRO99F, SER183I, VAL181I
• G-H: ALA100H, ALA18G, ALA71G, ALA73G, ALA96H, ARG68G, ARG82H, ARG8G, ARG9G, ASP17G, ASP25H, ASP2G, CYS74H, GLN70G, GLU102H, GLU28H, GLU89H, GLU91G, GLU92H, GLU98G, GLU98H, GLY26H, GLY33G, HIS10G, HIS27H, HIS35H, HIS68H, ILE14G, ILE22H, ILE30G, ILE30H, ILE34G, ILE65H, ILE7G, ILE90G, ILE90H, ILE95H, ILE99H, LEU101H, LEU21H, LEU35G, LEU5G, LEU70H, LYS11G, LYS20H, LYS32H, LYS72H, LYS80H, MET105H, MET17H, MET1G, MET6G, MET75H, PHE15G, PHE29H, PHE4G, PHE77H, PHE93G, PHE93H, PRO66H, PRO69G, PRO72G, PRO91H, PRO92G, PRO94H, PRO96G, PRO97G, PRO97H, SER23H, SER24H, SER64G, SER67H, SER71H, SER94G, SER95G, THR12G, THR13G, THR16G, THR74G, THR78H, THR88H, TYR18H, TYR76H, TYR79H, TYR83H, VAL19H, VAL31G, VAL31H, VAL3G, VAL69H, VAL73H, VAL81H
• G-I: GLU98G, LEU169I, LEU178I
• H-I: ALA100H, ALA106H, ALA107H, ALA96H, ARG161I, ARG167I, ARG177I, ARG79I, ARG82H, ARG82I, ASN108H, ASN131I, ASN150I, ASN78I, ASN85H, ASP111H, ASP121I, ASP126I, ASP179I, ASP187I, CYS112H, CYS162I, CYS74H, GLN132I, GLN164I, GLU102H, GLU160I, GLU89H, GLU92H, GLU98H, GLY104I, ILE151I, ILE180I, ILE90H, ILE95H, ILE99H, LEU101H, LEU103H, LEU104H, LEU110H, LEU128I, LEU129I, LEU153I, LEU158I, LEU163I, LEU169I, LEU178I, LEU184I, LEU188I, LEU70H, LYS159I, LYS72H, LYS80H, MET105H, MET75H, PHE109H, PHE77H, PHE93H, PRO103I, PRO154I, PRO81I, PRO91H, PRO94H, PRO97H, SER168I, SER183I, SER39H, SER80I, SER86H, SER87H, THR152I, THR157I, THR38H, THR84H, THR88H, TYR156I, TYR175I, TYR185I, TYR76H, TYR79H, TYR83H, VAL155I, VAL165I, VAL166I, VAL170I, VAL181I, VAL69H, VAL73H, VAL81H
• H-L: ASN85H, LYS171L
• J-K: ALA100K, ALA18J, ALA71J, ALA73J, ALA96K, ARG68J, ARG82K, ARG8J, ARG9J, ASP17J, ASP25K, ASP2J, CYS74K, GLN70J, GLU102K, GLU28K, GLU89K, GLU91J, GLU92K, GLU98J, GLU98K, GLY26K, GLY33J, HIS10J, HIS27K, HIS35K, HIS68K, ILE14J, ILE22K, ILE30J, ILE30K, ILE34J, ILE65K, ILE7J, ILE90J, ILE90K, ILE95K, ILE99K, LEU101K, LEU21K, LEU35J, LEU5J, LEU70K, LYS11J, LYS19J, LYS20K, LYS32K, LYS72K, LYS80K, MET105K, MET17K, MET1J, MET6J, MET75K, PHE15J, PHE29K, PHE4J, PHE77K, PHE93J, PHE93K, PRO66K, PRO69J, PRO72J, PRO91K, PRO92J, PRO94K, PRO96J, PRO97J, PRO97K, SER23K, SER24K, SER64J, SER67K, SER71K, SER94J, SER95J, THR12J, THR13J, THR16J, THR74J, THR78K, THR88K, TYR18K, TYR76K, TYR79K, TYR83K, VAL19K, VAL31J, VAL31K, VAL69K, VAL73K, VAL81K
• K-L: ALA100K, ALA106K, ALA107K, ALA96K, ARG161L, ARG167L, ARG177L, ARG79L, ARG82K, ARG82L, ASN108K, ASN131L, ASN150L, ASN78L, ASN85K, ASP111K, ASP121L, ASP126L, ASP179L, ASP187L, CYS112K, CYS162L, CYS74K, GLN132L, GLN164L, GLU102K, GLU160L, GLU89K, GLU92K, GLU98K, GLY104L, ILE151L, ILE180L, ILE90K, ILE95K, ILE99K, LEU101K, LEU103K, LEU104K, LEU110K, LEU128L, LEU129L, LEU153L, LEU158L, LEU163L, LEU169L, LEU178L, LEU184L, LEU188L, LEU70K, LYS159L, LYS72K, LYS80K, MET105K, MET75K, PHE109K, PHE77K, PHE93K, PRO103L, PRO154L, PRO81L, PRO91K, PRO94K, PRO97K, SER168L, SER183L, SER39K, SER80L, SER86K, SER87K, THR152L, THR157L, THR38K, THR84K, THR88K, TYR156L, TYR175L, TYR185L, TYR76K, TYR79K, TYR83K, VAL155L, VAL165L, VAL166L, VAL170L, VAL181L, VAL69K, VAL73K, VAL81K