1V1T

crystal structure of the pdz tandem of human syntenin in complex with tneykv peptide

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-S
  • Int. Res.: 42
  • Norm. En. per Res.: -4.47
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.5477	26.9504	-265.262	-263.8592	113	14	4	11156	2	26	18
A-T	-53.7847	1.7094	-121.973	-174.0483	41	7	7	4483	0	9	8
B-S	-61.7601	1.6659	-127.644	-187.7382	42	8	7	4472	0	9	7

Interface residues

• A-B: ALA167A, ALA167B, ALA227A, ALA227B, ALA228A, ALA228B, ALA272A, ALA272B, ARG191A, ARG191B, ARG193A, ARG193B, ARG197A, ARG197B, ARG229A, ARG229B, ASN134A, ASN134B, ASN165A, ASN165B, ASN230A, ASN230B, ASP133A, ASP133B, ASP192A, ASP192B, ASP224A, ASP224B, CYS166A, CYS166B, GLN157A, GLN157B, GLN160A, GLN160B, GLU164A, GLU164B, GLU196A, GLU196B, GLU235A, GLU235B, GLY135A, GLY135B, GLY163A, GLY163B, GLY168A, GLY168B, GLY231A, GLY231B, HIS236A, HIS236B, ILE132A, ILE132B, ILE136A, ILE136B, ILE199A, ILE199B, ILE218A, ILE218B, ILE221A, ILE221B, ILE269A, ILE269B, LEU159A, LEU159B, LEU232A, LEU232B, LEU233A, LEU233B, LYS173B, LYS217A, LYS217B, LYS223A, LYS223B, MET110A, MET201A, MET201B, MET270A, MET270B, PHE137A, PHE137B, PHE195A, PHE195B, PHE273A, PRO112A, PRO112B, PRO194A, PRO194B, PRO271A, PRO271B, SER131A, SER131B, SER220A, SER220B, SER225A, SER225B, SER226A, SER226B, THR189A, THR189B, THR198A, THR198B, THR200A, THR200B, THR219A, THR219B, THR234A, THR234B, TRP169A, TRP169B, VAL158A, VAL158B, VAL222A, VAL222B
• A-T: ALA227A, ALA255A, ASN215A, ASN2T, ASP204A, ASP251A, ASP256A, GLN253A, GLU3T, GLY207A, GLY210A, GLY216A, HIS208A, ILE212A, ILE218A, ILE221A, ILE238A, ILE241A, ILE254A, ILE267A, LEU232A, LEU258A, LYS203A, LYS214A, LYS217A, LYS223A, LYS250A, LYS5T, MET201A, PHE211A, PHE213A, SER220A, SER225A, SER252A, SER259A, THR219A, TYR4T, VAL209A, VAL222A, VAL265A, VAL6T
• B-S: ALA227B, ALA255B, ASN215B, ASN2S, ASP204B, ASP251B, ASP256B, GLN253B, GLU3S, GLY207B, GLY210B, GLY216B, HIS208B, ILE212B, ILE218B, ILE221B, ILE238B, ILE241B, ILE254B, ILE267B, LEU232B, LEU258B, LYS203B, LYS214B, LYS217B, LYS223B, LYS250B, LYS5S, MET201B, PHE211B, PHE213B, SER220B, SER225B, SER252B, SER259B, THR206B, THR219B, TYR4S, VAL209B, VAL222B, VAL265B, VAL6S