1V0F

endosialidase of bacteriophage k1f in complex with oligomeric alpha-2,8-sialic acid

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 496
  • Norm. En. per Res.: -7.0471
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-831.1812	-333.6535	-2275.35	-3440.1847	497	120	56	79684	25	128	109
A-C	-769.0962	-357.1678	-2153.06	-3279.324	498	106	55	78847	25	130	108
A-E	0.0	0.0	-16.3444	-16.3444	27	1	0	920	0	0	0
B-C	-885.4979	-324.0344	-2285.84	-3495.3723	496	128	58	80008	26	126	109
B-E	0.0	0.0	-6.1593	-6.1593	10	1	0	347	0	0	1
B-F	0.0	0.0	-0.0069	-0.0069	2	0	0	1	0	0	1
C-D	0.0	0.0	-18.4226	-18.4226	25	1	0	1056	0	0	0
C-E	0.0	-26.324	-7.3407	-33.6647	27	0	0	688	0	2	2
C-F	0.0	0.0	-6.1959	-6.1959	10	0	0	353	0	0	1
D-E	-767.8034	-329.0387	-2197.2	-3294.042	500	120	57	79254	23	128	108
D-F	-861.4007	-297.7221	-2296.32	-3455.4428	497	103	56	79850	25	127	110
E-F	-856.6826	-296.7257	-2298.84	-3452.2483	500	111	58	79831	21	128	109

Interface residues

• A-B: ALA307A, ALA663A, ALA734A, ALA768A, ALA768B, ALA773A, ALA773B, ALA788A, ALA788B, ALA805A, ALA805B, ALA834A, ALA852A, ALA852B, ALA859B, ALA879A, ALA879B, ALA890A, ALA890B, ALA901A, ALA901B, ARG288A, ARG293A, ARG421A, ARG425B, ARG660A, ARG667A, ARG672B, ARG759B, ARG762A, ARG762B, ARG765A, ARG765B, ARG772A, ARG772B, ARG784A, ARG784B, ARG804A, ARG804B, ARG812A, ARG812B, ARG837A, ARG837B, ARG865A, ARG865B, ARG866A, ARG866B, ARG897A, ARG897B, ASN272B, ASN274B, ASN291B, ASN326A, ASN338B, ASN458B, ASN461B, ASN500B, ASN650A, ASN687A, ASN712B, ASN725A, ASN732A, ASN758B, ASN771A, ASN771B, ASN781A, ASN781B, ASN810B, ASN832A, ASN832B, ASN860B, ASN861A, ASN861B, ASN870A, ASN870B, ASN885A, ASN885B, ASN887A, ASN887B, ASN896A, ASN896B, ASN906A, ASN906B, ASP285A, ASP321A, ASP321B, ASP364A, ASP364B, ASP365A, ASP365B, ASP377A, ASP470B, ASP690A, ASP711B, ASP722A, ASP731A, ASP736A, ASP736B, ASP741A, ASP741B, ASP746A, ASP757B, ASP763A, ASP763B, ASP779B, ASP795A, ASP795B, ASP831A, ASP831B, ASP863A, ASP863B, ASP872A, ASP872B, ASP880A, ASP880B, ASP886A, ASP886B, CYS749A, CYS841A, CYS841B, GLN269A, GLN313B, GLN367A, GLN367B, GLN691A, GLN694A, GLN836A, GLN836B, GLN853A, GLN853B, GLN877A, GLN877B, GLU309A, GLU309B, GLU310B, GLU315A, GLU337B, GLU373A, GLU373B, GLU649A, GLU721A, GLU791A, GLU791B, GLU814A, GLU814B, GLU818A, GLU818B, GLU820A, GLU820B, GLU844A, GLU844B, GLU873A, GLU873B, GLY268A, GLY273B, GLY275B, GLY314B, GLY346A, GLY363B, GLY366A, GLY366B, GLY469B, GLY504B, GLY695A, GLY696A, GLY730A, GLY742A, GLY742B, GLY755B, GLY767B, GLY782A, GLY782B, GLY794A, GLY794B, GLY797A, GLY797B, GLY799A, GLY799B, GLY819A, GLY819B, GLY822A, GLY822B, GLY825A, GLY825B, GLY835A, GLY835B, GLY842A, GLY842B, GLY843A, GLY843B, GLY845A, GLY845B, GLY851A, GLY858A, GLY858B, GLY871A, GLY871B, GLY892A, GLY892B, GLY893A, GLY893B, GLY904A, GLY904B, HIS356A, HIS428B, HIS502B, HIS508A, HIS508B, HIS723A, HIS743A, HIS800A, HIS800B, HIS874A, HIS874B, ILE271A, ILE286A, ILE290A, ILE290B, ILE319A, ILE340B, ILE688A, ILE692A, ILE697A, ILE754B, ILE803A, ILE803B, ILE811A, ILE811B, ILE824A, ILE824B, ILE828A, ILE828B, ILE838A, ILE838B, ILE839A, ILE839B, ILE854A, ILE854B, ILE867A, ILE867B, ILE908A, ILE908B, LEU262A, LEU283A, LEU316A, LEU375A, LEU378A, LEU427B, LEU429B, LEU747A, LEU796A, LEU796B, LEU798A, LEU798B, LEU816A, LEU816B, LEU856A, LEU856B, LEU875A, LEU875B, LEU891A, LEU891B, LEU903A, LEU903B, LYS270A, LYS276B, LYS318A, LYS361A, LYS361B, LYS509A, LYS509B, LYS662A, LYS710B, LYS739A, LYS739B, LYS751A, LYS751B, LYS753B, LYS826A, LYS826B, LYS882A, LYS882B, MET423B, MET471B, MET503B, MET790A, MET790B, MET817A, MET817B, PHE289A, PHE294A, PHE311B, PHE317A, PHE456B, PHE459B, PHE507A, PHE507B, PHE669A, PHE718A, PHE724A, PHE738A, PHE738B, PHE764A, PHE764B, PHE777A, PHE777B, PHE778A, PHE778B, PHE792A, PHE792B, PHE823A, PHE823B, PHE840A, PHE840B, PHE876A, PHE876B, PHE898A, PHE898B, PRO266A, PRO284A, PRO323A, PRO323B, PRO372A, PRO666A, PRO726A, PRO737A, PRO737B, PRO744A, PRO756B, PRO770A, PRO770B, PRO775A, PRO775B, PRO787A, PRO787B, PRO789A, PRO789B, PRO829A, PRO829B, PRO833A, PRO883A, PRO883B, PRO894A, PRO894B, PRO907A, PRO907B, SER282A, SER287A, SER308A, SER358A, SER362A, SER362B, SER370A, SER370B, SER424B, SER426B, SER460B, SER506B, SER510B, SER664A, SER733A, SER740A, SER740B, SER745A, SER761A, SER761B, SER806A, SER806B, SER808A, SER808B, SER813A, SER813B, SER827A, SER827B, SER847A, SER847B, SER848A, SER848B, SER864B, SER878A, SER878B, SER895A, SER895B, SER905A, SER905B, THR265A, THR292A, THR292B, THR320A, THR322A, THR322B, THR368A, THR368B, THR371A, THR371B, THR376A, THR505B, THR668A, THR689A, THR728A, THR780B, THR785A, THR785B, THR793A, THR793B, THR802A, THR802B, THR807A, THR807B, THR830A, THR830B, THR846A, THR846B, THR849A, THR850A, THR855A, THR855B, THR862B, THR889A, THR889B, THR899A, THR899B, THR900A, THR900B, THR910A, THR910B, TRP359A, TRP369A, TRP369B, TRP374A, TRP419A, TRP501B, TRP512A, TRP727A, TYR296A, TYR305A, TYR306A, TYR324A, TYR324B, TYR325A, TYR336B, TYR341B, TYR344A, TYR387A, TYR661A, TYR665A, TYR670B, TYR693A, TYR713B, TYR715B, TYR729A, TYR748A, TYR750A, TYR766A, TYR766B, TYR821A, TYR821B, TYR857A, TYR857B, TYR869A, TYR869B, TYR884A, TYR884B, TYR902A, TYR902B, VAL267A, VAL312B, VAL339B, VAL357A, VAL360A, VAL360B, VAL457B, VAL686A, VAL698A, VAL760B, VAL769A, VAL769B, VAL774A, VAL774B, VAL776A, VAL776B, VAL783A, VAL783B, VAL786A, VAL786B, VAL801A, VAL801B, VAL815A, VAL815B, VAL868A, VAL868B, VAL881A, VAL881B, VAL888A, VAL888B, VAL909A, VAL909B
• A-C: ALA307C, ALA663C, ALA734C, ALA768A, ALA768C, ALA773A, ALA773C, ALA788A, ALA788C, ALA805A, ALA805C, ALA834C, ALA852A, ALA852C, ALA859A, ALA879A, ALA879C, ALA890A, ALA890C, ALA901A, ALA901C, ARG288C, ARG293C, ARG354C, ARG421C, ARG425A, ARG660C, ARG667C, ARG672A, ARG759A, ARG762A, ARG762C, ARG765A, ARG765C, ARG772A, ARG772C, ARG784A, ARG784C, ARG804A, ARG804C, ARG812A, ARG812C, ARG837A, ARG837C, ARG865A, ARG865C, ARG866A, ARG866C, ARG897A, ARG897C, ASN272A, ASN274A, ASN291A, ASN326C, ASN338A, ASN458A, ASN461A, ASN500A, ASN650C, ASN687C, ASN712A, ASN725C, ASN732C, ASN758A, ASN771A, ASN771C, ASN781A, ASN781C, ASN810A, ASN810C, ASN832A, ASN832C, ASN860A, ASN861A, ASN861C, ASN870A, ASN870C, ASN885A, ASN885C, ASN887A, ASN887C, ASN896A, ASN896C, ASN906A, ASN906C, ASP285C, ASP321A, ASP321C, ASP364A, ASP364C, ASP365A, ASP365C, ASP377C, ASP470A, ASP690C, ASP711A, ASP722C, ASP731C, ASP736A, ASP736C, ASP741A, ASP741C, ASP746C, ASP757A, ASP763A, ASP763C, ASP779A, ASP795A, ASP795C, ASP831A, ASP831C, ASP863A, ASP872A, ASP872C, ASP880A, ASP880C, ASP886A, ASP886C, CYS749C, CYS841A, CYS841C, GLN269C, GLN313A, GLN367A, GLN367C, GLN691C, GLN694C, GLN836A, GLN836C, GLN853A, GLN853C, GLN877A, GLN877C, GLU309A, GLU309C, GLU310A, GLU310C, GLU315C, GLU337A, GLU373A, GLU373C, GLU649C, GLU721C, GLU791A, GLU791C, GLU814A, GLU814C, GLU818A, GLU818C, GLU820A, GLU820C, GLU844A, GLU844C, GLU873A, GLU873C, GLY268C, GLY273A, GLY275A, GLY314A, GLY346C, GLY363A, GLY366A, GLY366C, GLY469A, GLY504A, GLY695C, GLY696C, GLY730C, GLY742A, GLY742C, GLY755A, GLY767A, GLY782A, GLY782C, GLY794A, GLY794C, GLY797A, GLY797C, GLY799A, GLY799C, GLY819A, GLY819C, GLY822A, GLY822C, GLY825A, GLY825C, GLY835A, GLY835C, GLY842A, GLY842C, GLY843A, GLY843C, GLY845A, GLY845C, GLY851C, GLY858A, GLY858C, GLY871A, GLY871C, GLY892A, GLY892C, GLY893A, GLY893C, GLY904A, GLY904C, HIS356C, HIS428A, HIS502A, HIS508A, HIS508C, HIS723C, HIS743C, HIS800A, HIS800C, HIS874A, HIS874C, ILE271C, ILE286C, ILE290A, ILE290C, ILE319C, ILE340A, ILE688C, ILE692C, ILE697C, ILE754A, ILE803A, ILE803C, ILE811A, ILE811C, ILE824A, ILE824C, ILE828A, ILE828C, ILE838A, ILE838C, ILE839A, ILE839C, ILE854A, ILE854C, ILE867A, ILE867C, ILE908A, ILE908C, LEU262C, LEU283C, LEU316A, LEU316C, LEU375C, LEU378C, LEU427A, LEU429A, LEU747C, LEU796A, LEU796C, LEU798A, LEU798C, LEU816A, LEU816C, LEU856A, LEU856C, LEU875A, LEU875C, LEU891A, LEU891C, LEU903A, LEU903C, LYS270C, LYS276A, LYS318C, LYS361A, LYS361C, LYS509A, LYS509C, LYS662C, LYS710A, LYS739A, LYS739C, LYS751C, LYS753A, LYS826A, LYS826C, LYS882A, LYS882C, MET423A, MET471A, MET503A, MET752A, MET790A, MET790C, MET817A, MET817C, PHE289C, PHE294C, PHE311A, PHE317C, PHE456A, PHE459A, PHE507A, PHE507C, PHE669C, PHE718C, PHE724C, PHE738A, PHE738C, PHE764A, PHE764C, PHE777A, PHE777C, PHE778A, PHE778C, PHE792A, PHE792C, PHE823A, PHE823C, PHE840A, PHE840C, PHE876A, PHE876C, PHE898A, PHE898C, PRO266C, PRO284C, PRO323A, PRO323C, PRO372C, PRO666C, PRO726C, PRO737A, PRO737C, PRO744C, PRO756A, PRO770A, PRO770C, PRO775A, PRO775C, PRO787A, PRO787C, PRO789A, PRO789C, PRO829A, PRO829C, PRO833C, PRO883A, PRO883C, PRO894A, PRO894C, PRO907A, PRO907C, SER282C, SER287C, SER308C, SER358C, SER362A, SER362C, SER370A, SER370C, SER424A, SER426A, SER460A, SER506A, SER510A, SER664C, SER733C, SER740A, SER740C, SER745C, SER761A, SER761C, SER806A, SER806C, SER808A, SER808C, SER813A, SER813C, SER827A, SER827C, SER847A, SER847C, SER848A, SER848C, SER864A, SER878A, SER878C, SER895A, SER895C, SER905A, SER905C, THR265C, THR292A, THR292C, THR320C, THR322A, THR322C, THR368A, THR368C, THR371A, THR371C, THR376C, THR505A, THR668C, THR689C, THR728C, THR780A, THR785A, THR785C, THR793A, THR793C, THR802A, THR802C, THR807A, THR807C, THR830A, THR830C, THR846A, THR846C, THR849C, THR850C, THR855A, THR855C, THR889A, THR889C, THR899A, THR899C, THR900A, THR900C, THR910A, THR910C, TRP359C, TRP369A, TRP369C, TRP374C, TRP419C, TRP501A, TRP512C, TRP727C, TYR296C, TYR305C, TYR306C, TYR324A, TYR324C, TYR325C, TYR336A, TYR341A, TYR344C, TYR387C, TYR661C, TYR665C, TYR670A, TYR693C, TYR713A, TYR729C, TYR748C, TYR750C, TYR766A, TYR766C, TYR821A, TYR821C, TYR857A, TYR857C, TYR869A, TYR869C, TYR884A, TYR884C, TYR902A, TYR902C, VAL267C, VAL312A, VAL339A, VAL357C, VAL360A, VAL360C, VAL457A, VAL686C, VAL698C, VAL760A, VAL769A, VAL769C, VAL774A, VAL774C, VAL776A, VAL776C, VAL783A, VAL783C, VAL786A, VAL786C, VAL801A, VAL801C, VAL815A, VAL815C, VAL868A, VAL868C, VAL881A, VAL881C, VAL888A, VAL888C, VAL909A, VAL909C
• A-E: ALA547E, ARG440A, ARG440E, ARG549E, ASN438A, ASN438E, ASN488A, GLN489A, GLN490A, GLN543E, GLN570E, GLU550E, GLU574E, GLU576E, GLY466A, GLY904A, LEU494A, LYS435A, PRO487A, PRO548E, PRO577E, SER492A, SER522E, SER573E, THR465A, THR491A, VAL546E
• B-C: ALA307B, ALA663B, ALA734B, ALA768B, ALA768C, ALA773B, ALA773C, ALA788B, ALA788C, ALA805B, ALA805C, ALA834B, ALA852B, ALA852C, ALA859C, ALA879B, ALA879C, ALA890B, ALA890C, ALA901B, ALA901C, ARG288B, ARG293B, ARG354B, ARG421B, ARG425C, ARG660B, ARG667B, ARG672C, ARG759C, ARG762B, ARG762C, ARG765B, ARG765C, ARG772B, ARG772C, ARG784B, ARG784C, ARG804B, ARG804C, ARG812B, ARG812C, ARG837B, ARG837C, ARG865B, ARG865C, ARG866B, ARG866C, ARG897B, ARG897C, ASN272C, ASN274C, ASN291C, ASN326B, ASN338C, ASN458C, ASN461C, ASN500C, ASN650B, ASN687B, ASN712C, ASN725B, ASN732B, ASN758C, ASN771B, ASN771C, ASN781B, ASN781C, ASN810C, ASN832B, ASN832C, ASN860C, ASN861B, ASN861C, ASN870B, ASN870C, ASN885B, ASN885C, ASN887B, ASN887C, ASN896B, ASN896C, ASN906B, ASN906C, ASP285B, ASP321B, ASP321C, ASP364B, ASP364C, ASP365B, ASP365C, ASP377B, ASP470C, ASP690B, ASP711C, ASP722B, ASP731B, ASP736B, ASP736C, ASP741B, ASP741C, ASP746B, ASP757C, ASP763B, ASP763C, ASP779C, ASP795B, ASP795C, ASP831B, ASP831C, ASP863C, ASP872B, ASP872C, ASP880B, ASP880C, ASP886B, ASP886C, CYS749B, CYS841B, CYS841C, GLN269B, GLN313C, GLN367B, GLN367C, GLN691B, GLN694B, GLN836B, GLN836C, GLN853B, GLN853C, GLN877B, GLN877C, GLU309B, GLU309C, GLU310B, GLU310C, GLU315B, GLU337C, GLU373B, GLU373C, GLU649B, GLU721B, GLU791B, GLU791C, GLU814B, GLU814C, GLU818B, GLU818C, GLU820B, GLU820C, GLU844B, GLU844C, GLU873B, GLU873C, GLY268B, GLY273C, GLY275C, GLY314C, GLY346B, GLY363C, GLY366B, GLY366C, GLY469C, GLY504C, GLY695B, GLY696B, GLY730B, GLY742B, GLY742C, GLY755C, GLY767C, GLY782B, GLY782C, GLY794B, GLY794C, GLY797B, GLY797C, GLY799B, GLY799C, GLY819B, GLY819C, GLY822B, GLY822C, GLY825B, GLY825C, GLY835B, GLY835C, GLY842B, GLY842C, GLY843B, GLY843C, GLY845B, GLY845C, GLY851B, GLY858B, GLY858C, GLY871B, GLY871C, GLY892B, GLY892C, GLY893B, GLY893C, GLY904B, GLY904C, HIS356B, HIS428C, HIS502C, HIS508B, HIS508C, HIS723B, HIS743B, HIS800B, HIS800C, HIS874B, HIS874C, ILE271B, ILE286B, ILE290B, ILE290C, ILE319B, ILE340C, ILE688B, ILE692B, ILE697B, ILE754C, ILE803B, ILE803C, ILE811B, ILE811C, ILE824B, ILE824C, ILE828B, ILE828C, ILE838B, ILE838C, ILE839B, ILE839C, ILE854B, ILE854C, ILE867B, ILE867C, ILE908B, ILE908C, LEU262B, LEU283B, LEU316B, LEU316C, LEU375B, LEU378B, LEU427C, LEU747B, LEU796B, LEU796C, LEU798B, LEU798C, LEU816B, LEU816C, LEU856B, LEU856C, LEU875B, LEU875C, LEU891B, LEU891C, LEU903B, LEU903C, LYS270B, LYS276C, LYS318B, LYS361B, LYS361C, LYS509B, LYS509C, LYS662B, LYS710C, LYS739B, LYS739C, LYS751B, LYS753C, LYS826B, LYS826C, LYS882B, LYS882C, MET423C, MET471C, MET503C, MET790B, MET790C, MET817B, MET817C, PHE289B, PHE294B, PHE311C, PHE317B, PHE456C, PHE459C, PHE507B, PHE507C, PHE669B, PHE718B, PHE724B, PHE738B, PHE738C, PHE764B, PHE764C, PHE777B, PHE777C, PHE778B, PHE778C, PHE792B, PHE792C, PHE823B, PHE823C, PHE840B, PHE840C, PHE876B, PHE876C, PHE898B, PHE898C, PRO266B, PRO284B, PRO323B, PRO323C, PRO372B, PRO666B, PRO726B, PRO737B, PRO737C, PRO744B, PRO756C, PRO770B, PRO770C, PRO775B, PRO775C, PRO787B, PRO787C, PRO789B, PRO789C, PRO829B, PRO829C, PRO833B, PRO883B, PRO883C, PRO894B, PRO894C, PRO907B, PRO907C, SER282B, SER287B, SER308B, SER358B, SER362B, SER362C, SER370B, SER370C, SER424C, SER426C, SER460C, SER506C, SER510C, SER664B, SER733B, SER740B, SER740C, SER745B, SER761B, SER761C, SER806B, SER806C, SER808B, SER808C, SER813B, SER813C, SER827B, SER827C, SER847B, SER847C, SER848B, SER848C, SER864C, SER878B, SER878C, SER895B, SER895C, SER905B, SER905C, THR265B, THR292B, THR292C, THR320B, THR322B, THR322C, THR368B, THR368C, THR371B, THR371C, THR376B, THR505C, THR668B, THR689B, THR728B, THR780C, THR785B, THR785C, THR793B, THR793C, THR802B, THR802C, THR807B, THR807C, THR830B, THR830C, THR846B, THR846C, THR849B, THR850B, THR855B, THR855C, THR862C, THR889B, THR889C, THR899B, THR899C, THR900B, THR900C, THR910B, THR910C, TRP359B, TRP369B, TRP369C, TRP374B, TRP419B, TRP501C, TRP512B, TRP727B, TYR296B, TYR305B, TYR306B, TYR324B, TYR324C, TYR325B, TYR336C, TYR341C, TYR344B, TYR387B, TYR661B, TYR665B, TYR670C, TYR693B, TYR713C, TYR729B, TYR748B, TYR750B, TYR766B, TYR766C, TYR821B, TYR821C, TYR857B, TYR857C, TYR869B, TYR869C, TYR884B, TYR884C, TYR902B, TYR902C, VAL267B, VAL312C, VAL339C, VAL357B, VAL360B, VAL360C, VAL457C, VAL686B, VAL698B, VAL760C, VAL769B, VAL769C, VAL774B, VAL774C, VAL776B, VAL776C, VAL783B, VAL783C, VAL786B, VAL786C, VAL801B, VAL801C, VAL815B, VAL815C, VAL868B, VAL868C, VAL881B, VAL881C, VAL888B, VAL888C, VAL909B, VAL909C
• B-E: ARG440E, ARG897B, ASN438E, ASN896B, GLN439E, GLN489E, LEU485E, PRO894B, SER895B, TYR441E
• B-F: ASP831B, ASP831F
• C-D: ALA547C, ARG440D, ARG549C, ASN438C, ASN438D, ASN488D, GLN489D, GLN490D, GLN543C, GLN570C, GLU550C, GLU574C, GLU576C, GLY466D, GLY904D, LEU494D, LYS435D, PRO548C, PRO577C, SER492D, SER522C, SER573C, THR465D, THR491D, VAL546C
• C-E: ARG440C, ARG440E, ASN438C, ASN438E, ASN885C, ASN885E, ASN887C, ASN887E, ASP886C, ASP886E, GLN439C, GLN439E, GLN489C, GLN489E, LEU485C, LEU485E, LYS410C, LYS410E, THR384C, THR384E, THR491C, THR910C, THR910E, TYR441C, TYR441E, VAL888C, VAL888E
• C-F: ARG440C, ARG897F, ASN438C, ASN896F, GLN439C, GLN489C, LEU485C, PRO894F, SER895F, TYR441C
• D-E: ALA307E, ALA663E, ALA734E, ALA768D, ALA768E, ALA773D, ALA773E, ALA788D, ALA788E, ALA805D, ALA805E, ALA834E, ALA852D, ALA852E, ALA859D, ALA879D, ALA879E, ALA890D, ALA890E, ALA901D, ALA901E, ARG288E, ARG293E, ARG354E, ARG421E, ARG425D, ARG660E, ARG667E, ARG672D, ARG759D, ARG762D, ARG762E, ARG765D, ARG765E, ARG772D, ARG772E, ARG784D, ARG784E, ARG804D, ARG804E, ARG812D, ARG812E, ARG837D, ARG837E, ARG865D, ARG865E, ARG866D, ARG866E, ARG897D, ARG897E, ASN272D, ASN274D, ASN291D, ASN326E, ASN338D, ASN458D, ASN461D, ASN500D, ASN650E, ASN687E, ASN712D, ASN725E, ASN732E, ASN758D, ASN771D, ASN771E, ASN781D, ASN781E, ASN810D, ASN810E, ASN832D, ASN832E, ASN860D, ASN861D, ASN861E, ASN870D, ASN870E, ASN885D, ASN885E, ASN887D, ASN887E, ASN896D, ASN896E, ASN906D, ASN906E, ASP285E, ASP321D, ASP321E, ASP364D, ASP364E, ASP365D, ASP365E, ASP377E, ASP470D, ASP690E, ASP711D, ASP722E, ASP731E, ASP736D, ASP736E, ASP741D, ASP741E, ASP746E, ASP757D, ASP763D, ASP763E, ASP779D, ASP795D, ASP795E, ASP831D, ASP831E, ASP863D, ASP863E, ASP872D, ASP872E, ASP880D, ASP880E, ASP886D, ASP886E, CYS749E, CYS841D, CYS841E, GLN269E, GLN313D, GLN367D, GLN367E, GLN691E, GLN694E, GLN836D, GLN836E, GLN853D, GLN853E, GLN877D, GLN877E, GLU309D, GLU309E, GLU310D, GLU310E, GLU315E, GLU337D, GLU373D, GLU373E, GLU649E, GLU721E, GLU791D, GLU791E, GLU814D, GLU814E, GLU818D, GLU818E, GLU820D, GLU820E, GLU844D, GLU844E, GLU873D, GLU873E, GLY268E, GLY273D, GLY275D, GLY314D, GLY346E, GLY363D, GLY366D, GLY366E, GLY469D, GLY504D, GLY695E, GLY696E, GLY730E, GLY742D, GLY742E, GLY755D, GLY767D, GLY782D, GLY782E, GLY794D, GLY794E, GLY797D, GLY797E, GLY799D, GLY799E, GLY819D, GLY819E, GLY822D, GLY822E, GLY825D, GLY825E, GLY835D, GLY835E, GLY842D, GLY842E, GLY843D, GLY843E, GLY845D, GLY845E, GLY851E, GLY858D, GLY858E, GLY871D, GLY871E, GLY892D, GLY892E, GLY893D, GLY893E, GLY904D, GLY904E, HIS356E, HIS428D, HIS502D, HIS508D, HIS508E, HIS723E, HIS743E, HIS800D, HIS800E, HIS874D, HIS874E, ILE271E, ILE286E, ILE290D, ILE290E, ILE319E, ILE340D, ILE688E, ILE692E, ILE697E, ILE754D, ILE803D, ILE803E, ILE811D, ILE811E, ILE824D, ILE824E, ILE828D, ILE828E, ILE838D, ILE838E, ILE839D, ILE839E, ILE854D, ILE854E, ILE867D, ILE867E, ILE908D, ILE908E, LEU262E, LEU283E, LEU316D, LEU316E, LEU375E, LEU378E, LEU427D, LEU429D, LEU747E, LEU796D, LEU796E, LEU798D, LEU798E, LEU816D, LEU816E, LEU856D, LEU856E, LEU875D, LEU875E, LEU891D, LEU891E, LEU903D, LEU903E, LYS270E, LYS276D, LYS318D, LYS318E, LYS361D, LYS361E, LYS509D, LYS662E, LYS710D, LYS739D, LYS739E, LYS751E, LYS753D, LYS826D, LYS826E, LYS882D, LYS882E, MET423D, MET471D, MET503D, MET752D, MET790D, MET790E, MET817D, MET817E, PHE289E, PHE294E, PHE311D, PHE311E, PHE317E, PHE456D, PHE459D, PHE507D, PHE507E, PHE669E, PHE718E, PHE724E, PHE738D, PHE738E, PHE764D, PHE764E, PHE777D, PHE777E, PHE778D, PHE778E, PHE792D, PHE792E, PHE823D, PHE823E, PHE840D, PHE840E, PHE876D, PHE876E, PHE898D, PHE898E, PRO266E, PRO284E, PRO323D, PRO323E, PRO372E, PRO666E, PRO726E, PRO737D, PRO737E, PRO744E, PRO756D, PRO770D, PRO770E, PRO775D, PRO775E, PRO787D, PRO787E, PRO789D, PRO789E, PRO829D, PRO829E, PRO833E, PRO883D, PRO883E, PRO894D, PRO894E, PRO907D, PRO907E, SER282E, SER287E, SER308E, SER358E, SER362D, SER362E, SER370D, SER370E, SER424D, SER426D, SER460D, SER506D, SER510D, SER664E, SER733E, SER740D, SER740E, SER745E, SER761D, SER761E, SER806D, SER806E, SER808D, SER808E, SER813D, SER813E, SER827D, SER827E, SER847D, SER847E, SER848D, SER848E, SER864D, SER878D, SER878E, SER895D, SER895E, SER905D, SER905E, THR265E, THR292D, THR292E, THR320E, THR322D, THR322E, THR368D, THR368E, THR371D, THR371E, THR376E, THR505D, THR668E, THR689E, THR728E, THR780D, THR785D, THR785E, THR793D, THR793E, THR802D, THR802E, THR807D, THR807E, THR830D, THR830E, THR846D, THR846E, THR849E, THR850E, THR855D, THR855E, THR862D, THR889D, THR889E, THR899D, THR899E, THR900D, THR900E, THR910D, THR910E, TRP359E, TRP369D, TRP369E, TRP374E, TRP419E, TRP501D, TRP512E, TRP727E, TYR296E, TYR305E, TYR306E, TYR324D, TYR324E, TYR325E, TYR336D, TYR341D, TYR344E, TYR387E, TYR661E, TYR665E, TYR670D, TYR713D, TYR729E, TYR748E, TYR750E, TYR766D, TYR766E, TYR821D, TYR821E, TYR857D, TYR857E, TYR869D, TYR869E, TYR884D, TYR884E, TYR902D, TYR902E, VAL267E, VAL312D, VAL339D, VAL357E, VAL360D, VAL360E, VAL457D, VAL686E, VAL698E, VAL760D, VAL769D, VAL769E, VAL774D, VAL774E, VAL776D, VAL776E, VAL783D, VAL783E, VAL786D, VAL786E, VAL801D, VAL801E, VAL815D, VAL815E, VAL868D, VAL868E, VAL881D, VAL881E, VAL888D, VAL888E, VAL909D, VAL909E
• D-F: ALA307D, ALA663D, ALA734D, ALA768D, ALA768F, ALA773D, ALA773F, ALA788D, ALA788F, ALA805D, ALA805F, ALA834D, ALA852D, ALA852F, ALA859F, ALA879D, ALA879F, ALA890D, ALA890F, ALA901D, ALA901F, ARG288D, ARG293D, ARG354D, ARG421D, ARG425F, ARG660D, ARG667D, ARG672F, ARG759F, ARG762D, ARG762F, ARG765D, ARG765F, ARG772D, ARG772F, ARG784D, ARG784F, ARG804D, ARG804F, ARG812D, ARG812F, ARG837D, ARG837F, ARG865D, ARG865F, ARG866D, ARG866F, ARG897D, ARG897F, ASN263D, ASN272F, ASN274F, ASN291F, ASN326D, ASN338F, ASN458F, ASN461F, ASN500F, ASN650D, ASN687D, ASN712F, ASN725D, ASN732D, ASN758F, ASN771D, ASN771F, ASN781D, ASN781F, ASN810D, ASN810F, ASN832D, ASN832F, ASN860F, ASN861D, ASN861F, ASN870D, ASN870F, ASN885D, ASN885F, ASN887D, ASN887F, ASN896D, ASN896F, ASN906D, ASN906F, ASP285D, ASP321D, ASP321F, ASP364D, ASP364F, ASP365F, ASP377D, ASP470F, ASP690D, ASP711F, ASP722D, ASP731D, ASP736D, ASP736F, ASP741D, ASP741F, ASP746D, ASP757F, ASP763D, ASP763F, ASP779F, ASP795D, ASP795F, ASP831D, ASP831F, ASP863D, ASP863F, ASP872D, ASP872F, ASP880D, ASP880F, ASP886D, ASP886F, CYS749D, CYS841D, CYS841F, GLN269D, GLN313F, GLN367D, GLN367F, GLN691D, GLN694D, GLN836D, GLN836F, GLN853D, GLN853F, GLN877D, GLN877F, GLU309D, GLU309F, GLU310D, GLU310F, GLU315D, GLU337F, GLU373D, GLU373F, GLU649D, GLU721D, GLU791D, GLU791F, GLU814D, GLU814F, GLU818D, GLU818F, GLU820D, GLU820F, GLU844D, GLU844F, GLU873D, GLU873F, GLY268D, GLY273F, GLY275F, GLY314F, GLY346D, GLY363F, GLY366D, GLY366F, GLY469F, GLY504F, GLY695D, GLY696D, GLY730D, GLY742D, GLY742F, GLY755F, GLY767F, GLY782D, GLY782F, GLY794D, GLY794F, GLY797D, GLY797F, GLY799D, GLY799F, GLY819D, GLY819F, GLY822D, GLY822F, GLY825D, GLY825F, GLY835D, GLY835F, GLY842D, GLY842F, GLY843D, GLY843F, GLY845D, GLY845F, GLY851D, GLY858D, GLY858F, GLY871D, GLY871F, GLY892D, GLY892F, GLY893D, GLY893F, GLY904D, GLY904F, HIS356D, HIS428F, HIS502F, HIS508D, HIS508F, HIS723D, HIS743D, HIS800D, HIS800F, HIS874D, HIS874F, ILE271D, ILE286D, ILE290D, ILE290F, ILE319D, ILE340F, ILE688D, ILE692D, ILE697D, ILE754F, ILE803D, ILE803F, ILE811D, ILE811F, ILE824D, ILE824F, ILE828D, ILE828F, ILE838D, ILE838F, ILE839D, ILE839F, ILE854D, ILE854F, ILE867D, ILE867F, ILE908D, ILE908F, LEU262D, LEU283D, LEU316D, LEU375D, LEU378D, LEU427F, LEU429F, LEU747D, LEU796D, LEU796F, LEU798D, LEU798F, LEU816D, LEU816F, LEU856D, LEU856F, LEU875D, LEU875F, LEU891D, LEU891F, LEU903D, LEU903F, LYS270D, LYS276F, LYS318D, LYS361D, LYS361F, LYS509D, LYS509F, LYS662D, LYS710F, LYS739D, LYS739F, LYS751D, LYS753F, LYS826D, LYS826F, LYS882D, LYS882F, MET423F, MET503F, MET790D, MET790F, MET817D, MET817F, PHE289D, PHE294D, PHE311F, PHE317D, PHE456F, PHE459F, PHE507D, PHE507F, PHE669D, PHE718D, PHE724D, PHE738D, PHE738F, PHE764D, PHE764F, PHE777D, PHE777F, PHE778D, PHE778F, PHE792D, PHE792F, PHE823D, PHE823F, PHE840D, PHE840F, PHE876D, PHE876F, PHE898D, PHE898F, PRO266D, PRO284D, PRO323D, PRO323F, PRO372D, PRO666D, PRO726D, PRO737D, PRO737F, PRO744D, PRO756F, PRO770D, PRO770F, PRO775D, PRO775F, PRO787D, PRO787F, PRO789D, PRO789F, PRO829D, PRO829F, PRO833D, PRO883D, PRO883F, PRO894D, PRO894F, PRO907D, PRO907F, SER282D, SER287D, SER308D, SER358D, SER362D, SER362F, SER370D, SER370F, SER424F, SER426F, SER460F, SER506F, SER510F, SER664D, SER733D, SER740D, SER740F, SER745D, SER761D, SER761F, SER806D, SER806F, SER808D, SER808F, SER813D, SER813F, SER827D, SER827F, SER847D, SER847F, SER848D, SER848F, SER864F, SER878D, SER878F, SER895D, SER895F, SER905D, SER905F, THR265D, THR292D, THR292F, THR320D, THR322D, THR322F, THR368D, THR368F, THR371D, THR371F, THR376D, THR505F, THR668D, THR689D, THR728D, THR780F, THR785D, THR785F, THR793D, THR793F, THR802D, THR802F, THR807D, THR807F, THR830D, THR830F, THR846D, THR846F, THR849D, THR850D, THR855D, THR855F, THR862F, THR889D, THR889F, THR899D, THR899F, THR900D, THR900F, THR910D, THR910F, TRP359D, TRP369D, TRP369F, TRP374D, TRP419D, TRP501F, TRP512D, TRP727D, TYR296D, TYR305D, TYR306D, TYR324D, TYR324F, TYR325D, TYR336F, TYR341F, TYR344D, TYR387D, TYR661D, TYR665D, TYR670F, TYR693D, TYR713F, TYR729D, TYR748D, TYR750D, TYR766D, TYR766F, TYR821D, TYR821F, TYR857D, TYR857F, TYR869D, TYR869F, TYR884D, TYR884F, TYR902D, TYR902F, VAL267D, VAL312F, VAL339F, VAL357D, VAL360D, VAL360F, VAL457F, VAL686D, VAL698D, VAL760F, VAL769D, VAL769F, VAL774D, VAL774F, VAL776D, VAL776F, VAL783D, VAL783F, VAL786D, VAL786F, VAL801D, VAL801F, VAL815D, VAL815F, VAL868D, VAL868F, VAL881D, VAL881F, VAL888D, VAL888F, VAL909D, VAL909F
• E-F: ALA307F, ALA663F, ALA734F, ALA768E, ALA768F, ALA773E, ALA773F, ALA788E, ALA788F, ALA805E, ALA805F, ALA834F, ALA852E, ALA852F, ALA859E, ALA879E, ALA879F, ALA890E, ALA890F, ALA901E, ALA901F, ARG288F, ARG293F, ARG354F, ARG421F, ARG425E, ARG660F, ARG667F, ARG672E, ARG759E, ARG762E, ARG762F, ARG765E, ARG765F, ARG772E, ARG772F, ARG784E, ARG784F, ARG804E, ARG804F, ARG812E, ARG812F, ARG837E, ARG837F, ARG865E, ARG865F, ARG866E, ARG866F, ARG897E, ARG897F, ASN263F, ASN272E, ASN274E, ASN291E, ASN326F, ASN338E, ASN458E, ASN461E, ASN500E, ASN650F, ASN687F, ASN712E, ASN725F, ASN732F, ASN758E, ASN771E, ASN771F, ASN781E, ASN781F, ASN810E, ASN810F, ASN832E, ASN832F, ASN860E, ASN861E, ASN861F, ASN870E, ASN870F, ASN885E, ASN885F, ASN887E, ASN887F, ASN896E, ASN896F, ASN906E, ASN906F, ASP285F, ASP321E, ASP321F, ASP364E, ASP364F, ASP365E, ASP365F, ASP377F, ASP470E, ASP690F, ASP711E, ASP722F, ASP731F, ASP736E, ASP736F, ASP741E, ASP741F, ASP746F, ASP757E, ASP763E, ASP763F, ASP779E, ASP795E, ASP795F, ASP831E, ASP831F, ASP863E, ASP863F, ASP872E, ASP872F, ASP880E, ASP880F, ASP886E, ASP886F, CYS749F, CYS841E, CYS841F, GLN269F, GLN313E, GLN367E, GLN367F, GLN691F, GLN694F, GLN836E, GLN836F, GLN853E, GLN853F, GLN877E, GLN877F, GLU309E, GLU309F, GLU310E, GLU310F, GLU315F, GLU337E, GLU373E, GLU373F, GLU649F, GLU721F, GLU791E, GLU791F, GLU814E, GLU814F, GLU818E, GLU818F, GLU820E, GLU820F, GLU844E, GLU844F, GLU873E, GLU873F, GLY268F, GLY273E, GLY275E, GLY314E, GLY346F, GLY363E, GLY366E, GLY366F, GLY469E, GLY504E, GLY695F, GLY696F, GLY720F, GLY730F, GLY742E, GLY742F, GLY755E, GLY767E, GLY782E, GLY782F, GLY794E, GLY794F, GLY797E, GLY797F, GLY799E, GLY799F, GLY819E, GLY819F, GLY822E, GLY822F, GLY825E, GLY825F, GLY835E, GLY835F, GLY842E, GLY842F, GLY843E, GLY843F, GLY845E, GLY845F, GLY851F, GLY858E, GLY858F, GLY871E, GLY871F, GLY892E, GLY892F, GLY893E, GLY893F, GLY904E, GLY904F, HIS356F, HIS428E, HIS502E, HIS508E, HIS508F, HIS723F, HIS743F, HIS800E, HIS800F, HIS874E, HIS874F, ILE271F, ILE286F, ILE290E, ILE290F, ILE319F, ILE340E, ILE688F, ILE692F, ILE697F, ILE754E, ILE803E, ILE803F, ILE811E, ILE811F, ILE824E, ILE824F, ILE828E, ILE828F, ILE838E, ILE838F, ILE839E, ILE839F, ILE854E, ILE854F, ILE867E, ILE867F, ILE908E, ILE908F, LEU262F, LEU283F, LEU316E, LEU316F, LEU375F, LEU378F, LEU427E, LEU429E, LEU747F, LEU796E, LEU796F, LEU798E, LEU798F, LEU816E, LEU816F, LEU856E, LEU856F, LEU875E, LEU875F, LEU891E, LEU891F, LEU903E, LEU903F, LYS270F, LYS276E, LYS318F, LYS361E, LYS361F, LYS509E, LYS509F, LYS662F, LYS710E, LYS739E, LYS739F, LYS751F, LYS753E, LYS826E, LYS826F, LYS882E, LYS882F, MET423E, MET471E, MET503E, MET790E, MET790F, MET817E, MET817F, PHE289F, PHE294F, PHE311E, PHE317F, PHE456E, PHE459E, PHE507E, PHE507F, PHE669F, PHE718F, PHE724F, PHE738E, PHE738F, PHE764E, PHE764F, PHE777E, PHE777F, PHE778E, PHE778F, PHE792E, PHE792F, PHE823E, PHE823F, PHE840E, PHE840F, PHE876E, PHE876F, PHE898E, PHE898F, PRO266F, PRO284F, PRO323E, PRO323F, PRO372F, PRO666F, PRO726F, PRO737E, PRO737F, PRO744F, PRO756E, PRO770E, PRO770F, PRO775E, PRO775F, PRO787E, PRO787F, PRO789E, PRO789F, PRO829E, PRO829F, PRO833F, PRO883E, PRO883F, PRO894E, PRO894F, PRO907E, PRO907F, SER282F, SER287F, SER308F, SER358F, SER362E, SER362F, SER370E, SER370F, SER424E, SER426E, SER460E, SER506E, SER510E, SER664F, SER733F, SER740E, SER740F, SER745F, SER761E, SER761F, SER806E, SER806F, SER808E, SER808F, SER813E, SER813F, SER827E, SER827F, SER847E, SER847F, SER848E, SER848F, SER864E, SER878E, SER878F, SER895E, SER895F, SER905E, SER905F, THR265F, THR292E, THR292F, THR320F, THR322E, THR322F, THR368E, THR368F, THR371E, THR371F, THR376F, THR505E, THR668F, THR689F, THR728F, THR780E, THR785E, THR785F, THR793E, THR793F, THR802E, THR802F, THR807E, THR807F, THR830E, THR830F, THR846E, THR846F, THR849F, THR850F, THR855E, THR855F, THR862E, THR889E, THR889F, THR899E, THR899F, THR900E, THR900F, THR910E, THR910F, TRP359F, TRP369E, TRP369F, TRP374F, TRP419F, TRP501E, TRP512F, TRP727F, TYR296F, TYR305F, TYR306F, TYR324E, TYR324F, TYR325F, TYR336E, TYR341E, TYR344F, TYR661F, TYR665F, TYR670E, TYR693F, TYR713E, TYR729F, TYR748F, TYR750F, TYR766E, TYR766F, TYR821E, TYR821F, TYR857E, TYR857F, TYR869E, TYR869F, TYR884E, TYR884F, TYR902E, TYR902F, VAL267F, VAL312E, VAL339E, VAL357F, VAL360E, VAL360F, VAL457E, VAL686F, VAL698F, VAL760E, VAL769E, VAL769F, VAL774E, VAL774F, VAL776E, VAL776F, VAL783E, VAL783F, VAL786E, VAL786F, VAL801E, VAL801F, VAL815E, VAL815F, VAL868E, VAL868F, VAL881E, VAL881F, VAL888E, VAL888F, VAL909E, VAL909F