1UXK

large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 108
  • Norm. En. per Res.: -4.492
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-87.6307	-56.9054	-340.598	-485.1341	108	22	10	13669	4	20	20

Interface residues

• A-C: ALA149A, ALA149C, ALA157A, ALA157C, ALA160A, ALA160C, ALA169A, ALA169C, ALA239A, ALA239C, ARG153A, ARG153C, ARG184A, ARG184C, ARG246A, ARG246C, ASP166A, ASP166C, ASP243A, ASP243C, GLN165A, GLN165C, GLN168A, GLN168C, GLN235A, GLN235C, GLU195A, GLU195C, GLU238A, GLU238C, GLU277A, GLU277C, GLU281A, GLU281C, GLY161A, GLY161C, GLY190A, GLY190C, ILE188A, ILE188C, ILE191A, ILE191C, ILE270A, ILE270C, LEU171A, LEU171C, LEU182A, LEU182C, LEU271A, LEU271C, LEU280A, LEU280C, LEU282A, LEU282C, LEU284A, LEU284C, LYS244A, LYS244C, LYS245A, LYS245C, LYS24A, LYS278A, LYS278C, MET158C, MET170A, MET170C, MET248A, MET248C, PHE185A, PHE185C, PHE196A, PHE196C, PRO183A, PRO183C, PRO192A, PRO192C, PRO249A, PRO249C, PRO268A, PRO268C, PRO283A, PRO283C, SER163A, SER163C, SER186A, SER186C, SER189A, SER189C, THR187A, THR187C, TYR152A, TYR152C, TYR258A, TYR258C, VAL146C, VAL162A, VAL162C, VAL164A, VAL164C, VAL167A, VAL167C, VAL193A, VAL193C, VAL247A, VAL247C, VAL267C, VAL269A, VAL269C