1UUJ

n-terminal domain of lissencephaly-1 protein (lis-1)

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 120
  • Norm. En. per Res.: -4.767
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-48.8584	-23.9565	-499.227	-572.042	120	8	25	19670	3	37	44
A-D	-20.8346	40.0958	-114.377	-95.1158	43	4	0	4110	3	25	32
B-D	-9.3242	8.6676	-34.5394	-35.1959	27	1	0	1307	2	18	17
C-D	-46.6003	-20.1582	-502.702	-569.4605	128	9	27	20544	2	47	50

Interface residues

• A-B: ALA14A, ALA14B, ALA16A, ALA16B, ALA27A, ALA27B, ALA35A, ALA35B, ALA75A, ALA75B, ARG13A, ARG13B, ARG60A, ARG60B, ARG6A, ARG6B, ARG8A, ARG8B, ASN12A, ASN12B, ASN22A, ASN22B, ASN73A, ASN73B, ASP9A, ASP9B, GLN5B, GLN62A, GLN62B, GLN7A, GLN7B, GLU10A, GLU10B, GLU25A, GLU25B, GLU26A, GLU26B, GLU34A, GLU34B, GLU36A, GLU36B, GLU52A, GLU52B, GLU67A, GLU67B, GLU69A, GLU69B, GLU74A, GLU74B, GLY23A, GLY23B, GLY49B, ILE15A, ILE15B, ILE59A, ILE59B, LEU11A, LEU11B, LEU19A, LEU19B, LEU37B, LEU3A, LEU3B, LEU50A, LEU50B, LEU51A, LEU51B, LEU61A, LEU61B, LEU68A, LEU68B, LEU72A, LEU72B, LYS32A, LYS32B, LYS33A, LYS33B, LYS53A, LYS53B, LYS54A, LYS54B, LYS63A, LYS63B, LYS64A, LYS64B, LYS71A, LYS71B, LYS76A, PHE31A, PHE31B, SER21A, SER21B, SER29A, SER29B, SER4A, SER4B, SER57A, SER57B, SER70A, SER70B, THR56A, THR56B, TRP55A, TRP55B, TYR18A, TYR18B, TYR24A, TYR24B, TYR28A, TYR28B, TYR47A, TYR47B, VAL2A, VAL2B, VAL30A, VAL30B, VAL58A, VAL58B, VAL65A, VAL65B
• A-D: ALA27A, ALA35D, ALA48A, ARG13D, ARG20A, ARG6D, ARG8D, ASN12D, ASN22A, ASN40A, ASN40D, ASP17A, ASP38D, ASP44A, ASP44D, ASP9D, GLN5D, GLN7D, GLU10D, GLU25A, GLU26A, GLU36D, GLU41A, GLU41D, GLU42D, GLU52A, GLY23A, GLY49A, LEU11D, LEU19A, LEU37D, LEU43D, LYS32A, LYS33D, LYS45A, SER21A, SER29A, SER4D, TYR18A, TYR24A, TYR28A, TYR47D, VAL30A
• B-D: ALA35B, ARG13B, ARG13D, ARG6D, ARG8B, ASN12B, ASN40D, ASP38D, ASP44D, ASP9B, GLN5B, GLU10D, GLU34B, GLU36B, GLU41D, GLU42D, LEU37B, LEU3B, LEU43D, LYS33B, LYS45D, LYS46D, PHE31B, SER4B, TYR47D, VAL2B, VAL30B
• C-D: ALA14C, ALA14D, ALA16C, ALA16D, ALA27C, ALA27D, ALA35C, ALA35D, ALA75C, ALA75D, ARG13C, ARG13D, ARG60C, ARG60D, ARG6C, ARG6D, ARG8C, ARG8D, ASN12C, ASN12D, ASN22C, ASN22D, ASN73C, ASN73D, ASP9C, ASP9D, GLN5C, GLN62C, GLN62D, GLN7C, GLN7D, GLU10C, GLU10D, GLU25C, GLU25D, GLU26C, GLU26D, GLU34C, GLU34D, GLU36C, GLU36D, GLU52C, GLU52D, GLU67C, GLU67D, GLU69C, GLU69D, GLU74C, GLU74D, GLU78C, GLU78D, GLY23C, GLY23D, GLY49C, GLY49D, ILE15C, ILE15D, ILE59C, ILE59D, LEU11C, LEU11D, LEU19C, LEU19D, LEU37C, LEU37D, LEU3C, LEU3D, LEU50C, LEU50D, LEU51C, LEU51D, LEU61C, LEU61D, LEU68C, LEU68D, LEU72C, LEU72D, LYS32C, LYS32D, LYS33C, LYS33D, LYS46C, LYS53C, LYS53D, LYS54C, LYS54D, LYS63C, LYS63D, LYS64C, LYS64D, LYS71C, LYS71D, LYS76C, LYS76D, PHE31C, PHE31D, PHE79C, PHE79D, SER21C, SER21D, SER29C, SER29D, SER4C, SER4D, SER57C, SER57D, SER70C, SER70D, THR56C, THR56D, TRP55C, TRP55D, TYR18C, TYR18D, TYR24C, TYR24D, TYR28C, TYR28D, TYR47C, TYR47D, VAL2C, VAL2D, VAL30C, VAL30D, VAL58C, VAL58D, VAL65C, VAL65D