1UU0

histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 229
  • Norm. En. per Res.: -3.7947
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-130.5887	30.2914	-774.794	-875.0913	236	67	34	31931	0	57	55
A-C	-8.9935	-72.8516	-135.92	-217.7651	69	7	0	5499	7	71	63
A-D	-49.3116	-3.314	-63.9	-116.5256	33	7	0	2404	2	28	22
B-C	0.0	-4.6405	-1.7943	-6.4348	15	0	0	213	0	11	13
B-D	0.0	0.08	-47.7668	-47.6868	24	1	0	2036	0	32	31
C-D	-90.1472	-13.5196	-765.309	-868.9758	229	75	34	31921	0	59	55

Interface residues

• A-B: ALA113A, ALA113B, ALA115A, ALA115B, ALA118A, ALA118B, ALA11A, ALA175A, ALA175B, ALA207A, ALA207B, ALA208A, ALA208B, ALA223A, ALA223B, ALA25A, ALA25B, ALA49A, ALA49B, ALA85A, ALA85B, ALA8A, ARG10A, ARG19A, ARG210A, ARG210B, ARG226A, ARG226B, ARG228A, ARG228B, ARG254A, ARG254B, ARG308A, ARG308B, ARG315A, ARG315B, ARG43A, ARG43B, ARG44B, ARG51A, ARG51B, ASN149A, ASN225A, ASN225B, ASN232A, ASN232B, ASN27A, ASN27B, ASN282A, ASN282B, ASN29A, ASN29B, ASN46A, ASN46B, ASN77B, ASN83A, ASN83B, ASP222B, ASP36A, ASP36B, ASP39A, ASP39B, ASP48A, ASP48B, ASP55A, ASP55B, ASP58B, ASP86A, ASP86B, ASP97B, CYS108A, CYS108B, GLN209A, GLN209B, GLN238A, GLN238B, GLU138B, GLU15A, GLU17A, GLU218B, GLU28A, GLU28B, GLU323A, GLU323B, GLU35A, GLU35B, GLU40A, GLU40B, GLU59B, GLU87A, GLU87B, GLY117A, GLY117B, GLY139B, GLY319A, GLY319B, GLY82A, GLY82B, GLY84A, GLY84B, ILE111A, ILE111B, ILE221B, ILE318A, ILE318B, ILE52A, ILE52B, ILE62B, ILE7A, ILE88A, ILE88B, ILE89A, ILE89B, LEU206A, LEU206B, LEU229A, LEU229B, LEU24A, LEU24B, LEU26A, LEU26B, LEU37A, LEU37B, LEU45A, LEU45B, LEU50A, LEU50B, LEU94A, LEU94B, LYS114A, LYS114B, LYS18A, LYS202A, LYS202B, LYS219B, LYS21B, LYS320A, LYS320B, LYS9A, MET239A, MET239B, MET92A, MET92B, MET93A, MET93B, MET95A, MET95B, PHE112A, PHE112B, PHE169B, PHE200A, PHE200B, PHE204A, PHE204B, PHE220B, PHE231A, PHE231B, PHE240A, PHE240B, PHE251A, PHE251B, PHE31A, PHE31B, PHE33A, PHE33B, PHE42A, PHE42B, PHE96B, PRO13A, PRO230A, PRO230B, PRO30A, PRO30B, PRO32A, PRO32B, PRO34A, PRO34B, PRO57B, SER201A, SER201B, SER205A, SER205B, SER217B, SER234A, SER234B, SER237A, SER237B, SER47A, SER47B, SER56A, SER56B, SER80B, THR16A, THR199A, THR199B, THR22A, THR22B, THR317A, THR317B, TYR106A, TYR106B, TYR12A, TYR14A, TYR176A, TYR176B, TYR224A, TYR224B, TYR235A, TYR235B, TYR23A, TYR23B, TYR53A, TYR53B, TYR54A, TYR54B, TYR90A, TYR90B, VAL116A, VAL116B, VAL211A, VAL211B, VAL227A, VAL227B, VAL233A, VAL233B, VAL236A, VAL236B, VAL243A, VAL38A, VAL38B, VAL41A, VAL41B, VAL79B, VAL81B, VAL91A, VAL91B
• A-C: ALA11A, ALA25A, ALA306A, ARG10A, ARG19A, ARG254C, ARG295A, ARG301A, ARG308A, ARG311A, ARG43C, ARG44C, ASN46C, ASP20A, ASP246C, ASP36C, ASP39C, GLU15A, GLU17A, GLU249C, GLU253C, GLU289A, GLU291A, GLU294A, GLU298A, GLU35C, GLU40C, GLU59C, GLU60C, GLU63C, GLY313A, HIS247C, HIS299A, ILE250C, LEU296A, LEU297A, LEU300A, LEU37C, LEU45C, LEU50C, LYS18A, LYS290A, LYS293A, LYS320C, LYS64C, PHE240C, PHE251C, PHE257C, PHE310A, PHE31C, PHE33C, PHE42C, PRO13A, PRO30C, PRO32C, PRO34C, SER309A, SER47C, THR16A, THR302A, TYR12A, TYR14A, TYR23A, VAL243C, VAL305A, VAL307A, VAL314A, VAL38C, VAL41C
• A-D: ALA306A, ALA49D, ARG19A, ARG295A, ARG301A, ARG43D, ARG44D, ASN304A, ASN46D, ASP20A, ASP36D, ASP39D, ASP48D, GLU291A, GLU294A, GLU298A, GLU35D, GLU40D, HIS299A, LEU297A, LEU300A, LEU45D, LEU50D, LYS18A, LYS21A, LYS303A, PHE42D, SER47D, THR302A, TYR235D, VAL305A, VAL38D, VAL41D
• B-C: ALA49C, ARG226B, ARG44C, ARG51C, ASN46C, ASN77B, ASP48C, GLU59B, GLU59C, GLU60C, LYS219B, LYS64C, LYS76B, LYS76C, SER47C
• B-D: ARG301D, ASN304D, ASN78B, ASP186B, ASP20D, ASP72B, GLU322D, GLU330D, LEU66B, LEU74B, LYS189B, LYS190B, LYS21D, LYS303D, LYS76B, MET326D, PHE73B, PRO32D, SER67B, SER75B, THR22D, THR302D, THR71B, VAL305D
• C-D: ALA113D, ALA115C, ALA115D, ALA118D, ALA11D, ALA175C, ALA175D, ALA207C, ALA207D, ALA208C, ALA208D, ALA223C, ALA223D, ALA25C, ALA25D, ALA49C, ALA49D, ALA85C, ALA85D, ALA8D, ARG10D, ARG19D, ARG210C, ARG210D, ARG226C, ARG226D, ARG228C, ARG228D, ARG254C, ARG254D, ARG308C, ARG308D, ARG315C, ARG315D, ARG43C, ARG43D, ARG51C, ARG51D, ASN149C, ASN225C, ASN232C, ASN232D, ASN27C, ASN27D, ASN282C, ASN282D, ASN29C, ASN29D, ASN46C, ASN46D, ASN83C, ASN83D, ASP222C, ASP36C, ASP36D, ASP39C, ASP39D, ASP48C, ASP48D, ASP55C, ASP55D, ASP58C, ASP86C, ASP86D, ASP97C, CYS108C, CYS108D, GLN209C, GLN209D, GLN238C, GLN238D, GLU138C, GLU15D, GLU17D, GLU192C, GLU28C, GLU28D, GLU323C, GLU323D, GLU35C, GLU35D, GLU40C, GLU40D, GLU59C, GLU87C, GLU87D, GLY117C, GLY117D, GLY139C, GLY319C, GLY319D, GLY82C, GLY82D, GLY84C, GLY84D, ILE111C, ILE111D, ILE221C, ILE318C, ILE318D, ILE52C, ILE52D, ILE62C, ILE7D, ILE88C, ILE88D, ILE89C, ILE89D, LEU206C, LEU206D, LEU229C, LEU229D, LEU24C, LEU24D, LEU26C, LEU26D, LEU37C, LEU37D, LEU45C, LEU45D, LEU50C, LEU50D, LEU94C, LEU94D, LYS114C, LYS114D, LYS18D, LYS202C, LYS202D, LYS219C, LYS21C, LYS21D, LYS320C, LYS320D, LYS9D, MET239C, MET239D, MET92C, MET92D, MET93C, MET93D, MET95C, MET95D, PHE112C, PHE112D, PHE169C, PHE200C, PHE200D, PHE204C, PHE204D, PHE220C, PHE231C, PHE231D, PHE240C, PHE240D, PHE251C, PHE31C, PHE31D, PHE33C, PHE33D, PHE42C, PHE42D, PHE96C, PRO13D, PRO230C, PRO230D, PRO30C, PRO30D, PRO32C, PRO32D, PRO34C, PRO34D, PRO57C, SER107C, SER201C, SER201D, SER205C, SER205D, SER234C, SER234D, SER237C, SER237D, SER47C, SER47D, SER56C, SER56D, SER80C, THR16D, THR199C, THR199D, THR22C, THR22D, THR317C, THR317D, TYR106C, TYR106D, TYR12D, TYR14D, TYR176C, TYR176D, TYR224C, TYR224D, TYR235C, TYR235D, TYR23C, TYR23D, TYR53C, TYR53D, TYR54C, TYR54D, TYR90C, TYR90D, VAL116C, VAL116D, VAL211C, VAL211D, VAL227C, VAL227D, VAL233C, VAL233D, VAL236C, VAL236D, VAL38C, VAL38D, VAL41C, VAL41D, VAL81C, VAL91C, VAL91D