1UPN

complex of echovirus type 12 with domains 3 and 4 of its receptor decay accelerating factor (cd55) by cryo electron microscopy at 16 a

• Total interactions analyzed: 10
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 337
  • Norm. En. per Res.: -4.5533
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-133.9233	-26.6887	-595.567	-756.179	184	37	6	21867	2	25	15
A-C	-251.7081	-117.535	-1165.23	-1534.4732	337	90	26	46544	14	59	57
A-D	-65.4064	-2.6836	-329.056	-397.1461	121	39	7	14017	1	31	26
A-E	-20.3593	-15.9543	-9.5426	-45.8561	21	3	0	621	0	3	3
B-C	-68.7431	2.4865	-409.209	-475.4656	152	22	5	16146	0	6	4
B-D	-34.7402	-24.2634	-117.106	-176.1097	47	5	3	4722	3	7	9
B-E	-61.7426	-7.7262	515.782	446.3132	76	138	0	7918	1	10	12
C-D	-61.722	-18.2599	-229.633	-309.6149	83	16	2	8215	2	12	13
C-E	0.0	-24.6912	-17.0518	-41.743	19	0	0	997	2	2	1

Interface residues

• A-B: ALA130B, ALA173B, ALA191A, ALA198B, ALA260B, ALA29B, ALA33A, ALA47B, ALA85B, ARG104A, ARG105A, ARG114A, ARG12B, ARG14B, ARG193B, ARG215B, ARG251A, ARG254A, ARG256B, ARG37B, ARG98A, ASN142B, ASN164B, ASN172B, ASN181B, ASN190A, ASN191B, ASN194A, ASN195B, ASN196B, ASN205A, ASN206B, ASN207B, ASN211A, ASN212B, ASN218B, ASN260A, ASN265A, ASN30B, ASP138B, ASP197A, ASP211B, ASP270A, ASP45B, ASP84B, CYS121B, CYS134B, CYS197B, CYS256A, GLN167B, GLN188B, GLN204A, GLN257A, GLU108A, GLU129B, GLU131B, GLU143B, GLU148B, GLU35A, GLU46B, GLY133B, GLY139B, GLY145B, GLY149B, GLY159B, GLY174B, GLY176B, GLY178B, GLY180B, GLY189A, GLY198A, GLY206A, GLY209A, GLY37A, HIS144B, HIS187B, HIS201A, HIS216B, HIS217B, HIS38A, ILE109A, ILE169B, ILE184B, ILE188A, ILE190B, ILE200B, ILE205B, ILE271A, LEU101B, LEU122B, LEU123B, LEU146B, LEU182B, LEU192B, LEU213A, LEU255A, LEU261B, LYS259A, LYS81B, LYS87B, MET132B, MET175B, MET202B, MET210B, MET213B, MET222B, MET96B, PHE110A, PHE155B, PHE185A, PHE185B, PHE195A, PHE202A, PHE214B, PHE219B, PHE266A, PHE82B, PRO128B, PRO186B, PRO209B, PRO250A, PRO252A, PRO253A, PRO268A, PRO83B, SER135B, SER147B, SER168B, SER187A, SER193A, SER200A, SER203A, SER262A, SER267A, SER28B, THR111A, THR136B, THR140B, THR158B, THR160B, THR171B, THR183B, THR194B, THR199B, THR212A, THR220B, THR259B, THR263A, THR269A, THR272A, THR32A, THR36A, THR39A, THR48B, TRP189B, TRP199A, TRP248A, TRP80B, TYR100B, TYR112A, TYR192A, TYR196A, TYR208A, TYR210A, TYR258A, TYR35B, TYR97B, VAL113A, VAL124B, VAL127B, VAL137B, VAL141B, VAL166B, VAL170B, VAL177B, VAL179B, VAL207A, VAL208B, VAL249A, VAL264A, VAL31B, VAL32B, VAL33B, VAL34A
• A-C: ALA108C, ALA12A, ALA135C, ALA139C, ALA141C, ALA15A, ALA177A, ALA191A, ALA216C, ALA234C, ALA235C, ALA247A, ALA24C, ALA261A, ALA30A, ALA33A, ALA47C, ALA59C, ALA6A, ALA72A, ALA97A, ARG104A, ARG105A, ARG114A, ARG13A, ARG180A, ARG223C, ARG237A, ARG251A, ARG254A, ARG275A, ARG51A, ARG59A, ARG69C, ARG70A, ARG98A, ARG99A, ASN105C, ASN11C, ASN140C, ASN167A, ASN176A, ASN189C, ASN190A, ASN218C, ASN260A, ASN276A, ASN35C, ASN42C, ASN55A, ASN56C, ASN57C, ASN61C, ASN66A, ASP116A, ASP157C, ASP16A, ASP17C, ASP182C, ASP18C, ASP219C, ASP227C, ASP270A, ASP273A, ASP283A, ASP29C, ASP46A, ASP50C, ASP66C, ASP92C, CYS121C, CYS164C, CYS167C, CYS192C, CYS212C, CYS217C, CYS256A, CYS73A, GLN102A, GLN12C, GLN161C, GLN20C, GLN232C, GLN233C, GLN238C, GLN257A, GLN27C, GLN41A, GLN41C, GLN49A, GLN81C, GLN86C, GLN88C, GLU102C, GLU108A, GLU118A, GLU183C, GLU33C, GLU35A, GLU39C, GLU45C, GLU48C, GLU61A, GLU63C, GLU65A, GLY101C, GLY112C, GLY138C, GLY151C, GLY159C, GLY175A, GLY188C, GLY189A, GLY1A, GLY37A, GLY38C, GLY60C, GLY77A, GLY84C, GLY93C, HIS109C, HIS153C, HIS175C, HIS244A, HIS38A, HIS57A, HIS97C, ILE103C, ILE109A, ILE114C, ILE123A, ILE154C, ILE155C, ILE168C, ILE170A, ILE171C, ILE183A, ILE186A, ILE188A, ILE18A, ILE210C, ILE231C, ILE271A, ILE278A, ILE281A, ILE36C, ILE46C, ILE64A, ILE67C, ILE70C, LEU100C, LEU107A, LEU116C, LEU132C, LEU14C, LEU160C, LEU166C, LEU224C, LEU225C, LEU236C, LEU237C, LEU255A, LEU31A, LEU34C, LEU43C, LEU62C, LEU68A, LEU91C, LEU99C, LYS106A, LYS115C, LYS143C, LYS226C, LYS241A, LYS243A, LYS246A, LYS259A, LYS274A, LYS286A, LYS54A, LYS96C, MET100A, MET103A, MET181A, MET211C, MET238A, MET25C, MET44C, MET65C, MET76A, PHE110A, PHE115A, PHE118C, PHE120C, PHE121A, PHE13C, PHE185A, PHE19C, PHE213C, PHE220C, PHE230C, PHE240A, PHE28C, PHE67A, PHE83C, PHE85C, PHE95C, PRO137C, PRO142C, PRO148A, PRO149A, PRO168A, PRO169C, PRO178A, PRO179A, PRO184A, PRO229C, PRO22C, PRO250A, PRO252A, PRO253A, PRO268A, PRO26C, PRO282A, PRO287A, PRO29A, PRO32C, PRO37C, PRO44A, PRO54C, PRO71C, SER10C, SER111C, SER113C, SER162C, SER163C, SER169A, SER16C, SER172C, SER182A, SER186C, SER187A, SER193A, SER215C, SER21C, SER221C, SER23C, SER262A, SER267A, SER277A, SER40A, SER45A, SER51C, SER58A, SER60A, SER62A, SER63A, SER69A, SER71A, SER80C, THR111A, THR117C, THR120A, THR152C, THR15C, THR174C, THR17A, THR191C, THR228C, THR263A, THR269A, THR272A, THR279A, THR284A, THR31C, THR32A, THR36A, THR39A, THR43A, THR47A, THR50A, THR64C, THR98C, TRP110C, TRP156C, TRP170C, TRP193C, TRP248A, TRP93A, TYR106C, TYR107C, TYR112A, TYR134C, TYR146A, TYR176C, TYR192A, TYR239A, TYR258A, TYR280A, TYR56A, TYR68C, TYR75A, VAL101A, VAL113A, VAL117A, VAL119A, VAL119C, VAL122A, VAL14A, VAL158C, VAL165C, VAL190C, VAL214C, VAL222C, VAL245A, VAL249A, VAL285A, VAL28A, VAL30C, VAL34A, VAL3A, VAL40C, VAL42A, VAL48A, VAL49C, VAL4A, VAL52C, VAL53A, VAL53C, VAL55C, VAL58C, VAL72C, VAL74A, VAL7A, VAL82C, VAL87C, VAL94C
• A-D: ALA10A, ALA12A, ALA247A, ALA27A, ALA30A, ALA33A, ALA36D, ALA37D, ALA41D, ALA67D, ALA6A, ARG13A, ARG43D, ARG59A, ARG70A, ASN29D, ASN31D, ASN39D, ASN42D, ASN66A, ASN69D, ASN9A, ASP116A, ASP2A, ASP2A9, ASP35D, ASP45D, ASP46A, ASP49D, ASP59D, CB9.217594.10990, GLN26A, GLN41A, GLN44D, GLN48D, GLN4D, GLN8D, GLU118A, GLU14D, GLU35A, GLU55D, GLU5A, GLU61A, GLU65A, GLU8A, GLY1A, GLY37A, GLY51D, HIS244A, HIS26D, HIS38A, HIS57A, ILE183A, ILE30D, ILE60D, ILE64A, LEU31A, LEU65D, LEU68A, LEU68D, LYS241A, LYS243A, LYS246A, LYS52D, LYS58D, LYS63D, LYS9D, MET181A, MET61D, PHE110A, PHE115A, PHE185A, PHE46D, PHE53D, PHE67A, PRO184A, PRO242A, PRO250A, PRO29A, PRO50D, PRO56D, PRO66D, SER182A, SER25A, SER38D, SER40A, SER40D, SER58A, SER60A, SER62A, SER63A, SER64D, SER69A, SER6D, SER71A, THR10D, THR28D, THR32A, THR36A, THR39A, THR47D, THR54D, THR7D, TRP248A, TYR27D, TYR33D, TYR56A, VAL117A, VAL11A, VAL14A, VAL245A, VAL249A, VAL28A, VAL34A, VAL3A, VAL42A, VAL4A, VAL57D, VAL5D, VAL62D, VAL7A
• A-E: ARG275A, ARG90E, ASN205A, ASN276A, ASN35E, ASP270A, GLU106E, GLY22E, HIS107E, ILE109E, LYS274A, PRO21E, PRO268A, SER108E, SER267A, SER92E, THR269A, THR36E, THR94E, TYR110E, TYR89E
• B-C: ALA124C, ALA126C, ALA157B, ALA173B, ALA202C, ALA47B, ALA47C, ARG103B, ARG12B, ARG193B, ARG37B, ARG43B, ARG69C, ASN172B, ASN181B, ASN191B, ASN195B, ASN206B, ASN207B, ASN230B, ASN35C, ASN61C, ASP11B, ASP157C, ASP234B, ASP45B, ASP50C, ASP66C, ASP74B, CYS121B, CYS121C, CYS208C, CYS212C, GLN119B, GLN161C, GLU102C, GLU27B, GLU33C, GLU39C, GLU40B, GLU45C, GLU46B, GLU48C, GLU63C, GLY101C, GLY120B, GLY122C, GLY128C, GLY159B, GLY159C, GLY178B, GLY180B, GLY203C, GLY34B, GLY36B, GLY38C, GLY77B, HIS118B, HIS187B, HIS97C, ILE103C, ILE169B, ILE184B, ILE190B, ILE205B, ILE210C, ILE224B, ILE36C, ILE46C, ILE67C, ILE70C, LEU100C, LEU122B, LEU123B, LEU160C, LEU182B, LEU192B, LEU229B, LEU34C, LEU42B, LEU62C, LEU99C, LYS116B, LYS73B, LYS96C, MET125C, MET202B, MET210B, MET211C, MET65C, PHE117B, PHE120C, PHE185B, PHE213C, PHE226B, PRO128B, PRO186B, PRO201C, PRO203B, PRO205C, PRO209B, PRO225B, PRO228B, PRO32C, PRO37C, PRO39B, PRO54C, PRO76B, SER10B, SER115B, SER123C, SER156B, SER162C, SER163C, SER207C, SER209C, SER232B, SER233B, SER51C, SER75B, THR127C, THR158B, THR171B, THR183B, THR194B, THR204C, THR206C, THR31C, THR48B, THR64C, THR98C, TRP156C, TRP189B, TRP38B, TYR204B, TYR231B, TYR35B, TYR68C, VAL119C, VAL158C, VAL170B, VAL177B, VAL179B, VAL200C, VAL208B, VAL214C, VAL227B, VAL33B, VAL40C, VAL49C, VAL52C, VAL53C
• B-D: ALA29B, ALA67D, ARG12B, ARG14B, ARG193B, ARG37B, ASN191B, ASN195B, ASN30B, ASN69D, ASP11B, ASP59D, GLN188B, GLU27B, GLU55D, GLY34B, GLY36B, GLY51D, HIS187B, ILE16B, ILE184B, ILE200B, ILE60D, LEU68D, LYS52D, LYS58D, MET61D, PHE185B, PHE53D, PRO186B, PRO56D, PRO66D, SER10B, SER15B, SER28B, THR183B, THR194B, THR199B, THR54D, TRP38B, TYR35B, VAL13B, VAL201B, VAL31B, VAL32B, VAL33B, VAL57D
• B-E: ALA152B, ALA157B, ARG14E, ARG90E, ASN142B, ASN15E, ASN161B, ASN164B, ASN35E, ASN9E, ASP19E, ASP74B, CYS134B, CYS34E, CYS64E, GLN167B, GLN17E, GLU12E, GLU143B, GLU148B, GLU150B, GLU66E, GLU72B, GLY11E, GLY145B, GLY149B, GLY159B, GLY162B, GLY16E, GLY22E, GLY23E, GLY37E, HIS144B, ILE13E, ILE169B, ILE18E, ILE24E, ILE30E, ILE67E, LEU25E, LEU261B, LEU40E, LEU61E, LYS153B, LYS154B, LYS39E, PHE155B, PHE32E, PRO10E, PRO21E, PRO76B, SER135B, SER147B, SER156B, SER168B, SER31E, SER33E, SER75B, THR136B, THR140B, THR151B, THR158B, THR160B, THR163B, THR165B, THR171B, THR36E, TRP78B, TRP79B, TYR38E, TYR89E, VAL113E, VAL141B, VAL166B, VAL170B, VAL20E
• C-D: ALA216C, ALA24C, ALA36D, ALA37D, ALA41D, ALA47C, ALA67D, ARG223C, ARG43D, ASN218C, ASN29D, ASN31D, ASN35C, ASN39D, ASN42C, ASN42D, ASN69D, ASP17C, ASP18C, ASP35D, ASP45D, ASP49D, ASP50C, CYS164C, GLN161C, GLN20C, GLN27C, GLN41C, GLN44D, GLN48D, GLN4D, GLU39C, GLU45C, GLU48C, GLU55D, GLY159C, GLY38C, GLY51D, ILE30D, ILE36C, ILE46C, LEU160C, LEU225C, LEU43C, LEU65D, LEU68D, LEU99C, LYS115C, LYS34D, LYS52D, LYS63D, LYS9D, MET25C, MET44C, MET61D, PHE19C, PHE220C, PHE28C, PHE46D, PHE53D, PRO22C, PRO26C, PRO37C, PRO50D, PRO56D, PRO66D, SER162C, SER163C, SER16C, SER215C, SER21C, SER23C, SER38D, SER40D, THR15C, THR47D, THR54D, TYR32D, TYR33D, VAL165C, VAL30C, VAL40C, VAL49C
• C-E: ALA59C, ARG84E, ARG90E, ASN61C, CYS111E, GLN91E, GLU63C, GLY60C, HIS107E, ILE109E, LEU62C, SER108E, SER92E, THR64C, THR94E, TYR110E, TYR89E, VAL58C, VAL93E