1UL1

crystal structure of the human fen1-pcna complex

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: X-A
  • Int. Res.: 140
  • Norm. En. per Res.: -5.6008
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
X-A	-156.1692	-140.2214	-487.728	-784.1186	140	38	15	18533	15	65	33
Y-B	-110.3137	-51.1883	-420.95	-582.452	114	40	15	16145	4	51	43
Z-C	-105.6216	-32.757	-372.099	-510.4777	102	28	14	13797	4	35	24
A-B	-90.0912	-8.111	-177.112	-275.3141	74	16	0	7622	2	26	34
A-C	-76.7656	-23.4818	-178.36	-278.6074	74	17	2	7450	2	29	27
B-C	-98.2617	-11.3853	-197.533	-307.18	75	13	0	7722	1	25	30

Interface residues

• X-A: ALA169X, ALA174X, ALA208A, ALA231A, ALA252A, ALA26A, ALA353X, ALA67A, ALA96A, ARG19X, ARG211X, ARG29X, ARG332X, ARG339X, ARG355X, ARG64A, ASN200A, ASN21X, ASN36A, ASN65A, ASN95A, ASP120A, ASP122A, ASP232A, ASP257A, ASP29A, ASP341X, ASP342X, ASP41A, ASP94A, ASP97A, CYS27A, GLN125A, GLN131A, GLN204A, GLN333X, GLN337X, GLN38A, GLU124A, GLU130A, GLU132A, GLU201A, GLU206X, GLU256A, GLU258A, GLU259A, GLU292X, GLU295X, GLU300X, GLU357X, GLU93A, GLY127A, GLY170X, GLY28X, GLY334X, GLY338X, GLY348X, GLY69A, GLY78X, HIS208X, HIS44A, ILE128A, ILE255A, ILE30A, LEU118A, LEU121A, LEU126A, LEU166X, LEU205A, LEU209X, LEU235A, LEU251A, LEU296X, LEU340X, LEU350X, LEU37A, LEU47A, LEU66A, LYS117A, LYS168X, LYS171X, LYS254A, LYS297X, LYS30X, LYS345X, LYS354X, LYS356X, LYS80X, MET116A, MET119A, MET199A, MET229A, MET40A, MET68A, PHE207A, PHE215A, PHE27X, PHE343X, PHE344X, PRO129A, PRO151X, PRO188X, PRO202A, PRO234A, PRO253A, SER134A, SER210X, SER230A, SER25X, SER299X, SER335X, SER349X, SER351X, SER352X, SER39A, SER43A, SER46A, THR206A, THR336X, THR347X, THR98A, TRP28A, TRP298X, TYR133A, TYR173X, TYR211A, TYR249A, TYR250A, TYR26X, VAL123A, VAL167X, VAL172X, VAL189X, VAL203A, VAL233A, VAL236A, VAL346X, VAL45A, VAL48A, VAL70A
• Y-B: ALA157B, ALA208B, ALA231B, ALA252B, ALA26B, ALA353Y, ALA67B, ALA96B, ARG19Y, ARG29Y, ARG339Y, ARG355Y, ASN21Y, ASN24B, ASN36B, ASN65B, ASN77Y, ASN95B, ASP120B, ASP122B, ASP156B, ASP22Y, ASP232B, ASP257B, ASP29B, ASP341Y, ASP342Y, ASP41B, ASP94B, ASP97B, CYS27B, GLN125B, GLN131B, GLN333Y, GLN337Y, GLN38B, GLU115B, GLU124B, GLU256B, GLU357Y, GLU359Y, GLU93B, GLY127B, GLY28Y, GLY334Y, GLY338Y, GLY348Y, GLY69B, GLY78Y, HIS44B, ILE128B, ILE23Y, ILE255B, ILE30B, LEU118B, LEU121B, LEU126B, LEU205B, LEU235B, LEU251B, LEU340Y, LEU350Y, LEU37B, LEU47B, LEU66B, LYS117B, LYS24Y, LYS254B, LYS30Y, LYS330Y, LYS345Y, LYS354Y, LYS356Y, LYS80Y, MET116B, MET119B, MET40B, MET68B, PHE207B, PHE215B, PHE27Y, PHE343Y, PHE344Y, PRO129B, PRO234B, PRO253B, PRO358Y, SER230B, SER25Y, SER335Y, SER349Y, SER351Y, SER352Y, SER39B, SER42B, SER43B, SER46B, THR206B, THR336Y, THR347Y, THR98B, TRP28B, TYR133B, TYR211B, TYR249B, TYR250B, TYR26Y, VAL123B, VAL233B, VAL236B, VAL346Y, VAL45B, VAL48B, VAL70B
• Z-C: ALA157C, ALA208C, ALA231C, ALA252C, ALA26C, ALA353Z, ALA67C, ALA96C, ARG19Z, ARG210C, ARG211Z, ARG29Z, ARG332Z, ARG339Z, ARG355Z, ARG64C, ASN21Z, ASN36C, ASN65C, ASN95C, ASP120C, ASP122C, ASP232C, ASP29C, ASP341Z, ASP342Z, ASP41C, ASP94C, ASP97C, CYS27C, GLN125C, GLN131C, GLN333Z, GLN337Z, GLN38C, GLU124C, GLU93C, GLY127C, GLY28Z, GLY334Z, GLY338Z, GLY348Z, GLY69C, HIS208Z, HIS44C, ILE128C, ILE255C, ILE30C, LEU118C, LEU121C, LEU126C, LEU235C, LEU251C, LEU340Z, LEU350Z, LEU37C, LEU47C, LEU66C, LYS117C, LYS254C, LYS30Z, LYS345Z, LYS354Z, LYS356Z, LYS80Z, MET116C, MET119C, MET40C, MET68C, PHE207C, PHE215C, PHE27Z, PHE343Z, PHE344Z, PRO129C, PRO234C, PRO253C, SER25Z, SER335Z, SER349Z, SER351Z, SER352Z, SER39C, SER42C, SER43C, SER46C, THR206C, THR336Z, THR347Z, THR98C, TRP28C, TYR133C, TYR211C, TYR249C, TYR250C, VAL123C, VAL233C, VAL236C, VAL346Z, VAL45C, VAL48C, VAL70C
• A-B: ALA100A, ALA105A, ALA171B, ALA194B, ALA82A, ARG146B, ARG149B, ASN107A, ASN177B, ASN179B, ASN187B, ASN71A, ASN84A, ASP113A, ASP150B, CYS81A, GLN108A, GLN184B, GLU109A, GLU115A, GLU143B, GLU174B, GLU191B, GLU192B, GLU193B, GLY142B, GLY155B, GLY166B, GLY173B, GLY176B, GLY178B, GLY83A, HIS153B, ILE147B, ILE154B, ILE180B, ILE78A, LEU101A, LEU118A, LEU151B, LEU175B, LEU182B, LEU79A, LEU99A, LYS110A, LYS117A, LYS13A, LYS168B, LYS181B, LYS190B, LYS77A, LYS80A, MET116A, MET75A, PHE103A, PHE144B, PHE169B, PRO106A, PRO140B, SER112A, SER152B, SER170B, SER172B, SER183B, SER74A, SER76A, THR185B, THR73A, THR98A, TYR114A, VAL102A, VAL111A, VAL167B, VAL195B
• A-C: ALA105C, ALA171A, ALA194A, ALA82C, ARG146A, ARG149A, ASN107C, ASN177A, ASN179A, ASN71C, ASN84C, ASP113C, ASP150A, ASP86C, CYS81C, GLN108C, GLN184A, GLU104C, GLU109C, GLU115C, GLU143A, GLU174A, GLU191A, GLU193A, GLU85C, GLY142A, GLY155A, GLY166A, GLY173A, GLY176A, GLY178A, GLY83C, HIS153A, ILE147A, ILE154A, ILE180A, ILE78C, LEU101C, LEU118C, LEU151A, LEU175A, LEU182A, LEU79C, LEU99C, LYS110C, LYS117C, LYS13C, LYS168A, LYS181A, LYS77C, LYS80C, MET116C, MET75C, PHE103C, PHE144A, PHE169A, PRO106C, PRO140A, SER112C, SER152A, SER170A, SER172A, SER183A, SER186A, SER74C, SER76C, THR185A, THR73C, THR98C, TYR114C, VAL102C, VAL111C, VAL167A, VAL195A
• B-C: ALA100B, ALA105B, ALA171C, ALA194C, ALA82B, ARG146C, ARG149C, ASN107B, ASN177C, ASN179C, ASN187C, ASN71B, ASN84B, ASP113B, ASP150C, ASP189C, ASP86B, CYS148C, CYS81B, GLN108B, GLN184C, GLU109B, GLU115B, GLU143C, GLU174C, GLU193C, GLY142C, GLY155C, GLY173C, GLY176C, GLY178C, GLY83B, HIS153C, ILE147C, ILE154C, ILE180C, ILE78B, LEU101B, LEU151C, LEU175C, LEU182C, LEU79B, LEU99B, LYS110B, LYS117B, LYS13B, LYS168C, LYS181C, LYS190C, LYS77B, LYS80B, MET116B, MET75B, PHE103B, PHE144C, PHE169C, PRO106B, PRO140C, SER112B, SER152C, SER170C, SER172C, SER183C, SER186C, SER74B, SER76B, THR185C, THR73B, THR98B, TYR114B, VAL102B, VAL111B, VAL167C, VAL188C, VAL195C