1UK1

crystal structure of human poly(adp-ribose) polymerase complexed with a potent inhibitor

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 86
  • Norm. En. per Res.: -1.4808
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-8.1986	20.2088	-139.355	-127.3448	86	3	1	6278	1	26	27

Interface residues

• A-B: ALA685A, ARG735B, ARG865A, ASN1008A, ASN734B, ASN753B, ASP671A, ASP678A, ASP692A, ASP692B, ASP726B, ASP731B, ASP743A, ASP743B, ASP830A, ASP914A, GLN694A, GLN694B, GLN705B, GLN722B, GLN728B, GLN912A, GLU680A, GLU688A, GLU690A, GLU832A, GLY723B, GLY745A, GLY745B, GLY913A, HIS742A, HIS742B, HIS909A, ILE691A, ILE729B, ILE740B, ILE834A, ILE916A, LEU693A, LEU730B, LEU739B, LEU751B, LEU752B, LYS1004A, LYS1006A, LYS1010A, LYS667A, LYS674A, LYS683A, LYS684A, LYS695B, LYS747A, LYS747B, LYS748B, MET675A, MET682A, MET686A, MET696B, MET746A, MET746B, PHE1007A, PHE1009A, PHE736B, PHE744A, PHE744B, PRO668A, PRO697B, PRO741B, PRO749B, PRO750B, PRO915A, SER681A, SER724B, SER725B, SER727B, SER733B, SER911A, THR1011A, THR738B, THR866A, THR867A, THR910A, TYR689A, TYR737B, VAL679A, VAL687A