1UHL

crystal structure of the lxralfa-rxrbeta lbd heterodimer

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 43
  • Norm. En. per Res.: -3.8727
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-22.8089	-97.6046	-210.11	-330.5235	107	13	7	10205	6	45	43
A-C	-25.7495	-13.8196	-126.959	-166.5281	43	10	8	5700	1	16	6
B-D	-16.9668	-7.2723	-99.552	-123.791	45	12	6	5367	0	18	12

Interface residues

• A-B: ALA345B, ALA367B, ALA391B, ALA469A, ALA487A, ALA495A, ARG369B, ARG380B, ARG401B, ARG406B, ARG415B, ARG419A, ARG464A, ARG485A, ARG492A, ARG497A, ASN371B, ASN448A, ASP368B, ASP400B, ASP430A, ASP450A, GLN210B, GLN375B, GLN382B, GLN482A, GLN483A, GLU296B, GLU341B, GLU348B, GLU378A, GLU379B, GLU387B, GLU423A, GLU423B, GLU461A, GLU465A, GLU472A, GLU505A, GLY453A, GLY484A, GLY500A, HIS383B, HIS390B, ILE362B, ILE444A, ILE445A, ILE499A, LEU349B, LEU359B, LEU376B, LEU389B, LEU402B, LEU408B, LEU411B, LEU414B, LEU417B, LEU424A, LEU441A, LEU471A, LEU489A, LEU490A, LEU491A, LEU493A, LEU496A, LEU501A, LYS410B, LYS427A, LYS452A, LYS466A, LYS476A, LYS488A, LYS502A, MET206B, MET403B, MET407B, MET409B, MET431A, PHE342B, PHE365B, PHE404B, PHE486A, PRO338B, PRO370B, PRO405B, PRO449A, PRO494A, SER363B, SER366B, SER394B, SER413B, SER418B, SER419B, SER458A, SER470A, SER498A, THR384B, THR416B, THR422A, THR473A, TYR468A, VAL372B, VAL386B, VAL412B, VAL420B, VAL462A, VAL467A
• A-C: ALA354A, ALA374A, ALA528A, ARG373A, ARG609C, ASP344A, ASP366A, ASP367A, ASP519A, GLN368A, GLN612C, GLU352A, GLU524A, GLU527A, HIS604C, HIS608C, ILE370A, ILE606C, LEU347A, LEU350A, LEU363A, LEU365A, LEU371A, LEU372A, LEU446A, LEU522A, LEU607C, LEU610C, LEU611C, LYS355A, LYS605C, MET523A, MET525A, PHE348A, PHE360A, PHE521A, PRO364A, SER361A, THR349A, THR520A, TRP376A, VAL351A, VAL369A
• B-D: ALA272B, ALA288B, ALA294B, ARG227B, ARG283B, ARG609D, ASP270B, ASP285B, ASP444B, ASP613D, GLN266B, GLN286B, GLN612D, GLU267B, GLU284B, GLU441B, HIS604D, HIS608D, ILE262B, ILE268B, ILE287B, ILE442B, ILE606D, LEU279B, LEU281B, LEU289B, LEU290B, LEU438B, LEU439B, LEU607D, LEU610D, LEU611D, LYS273B, LYS291B, LYS605D, PHE278B, PRO436B, PRO437B, SER264B, SER282B, SER440B, TRP443B, VAL263B, VAL265B, VAL269B