1UFQ

crystal structure of ligand-free human uridine-cytidine kinase 2

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 60
  • Norm. En. per Res.: -3.1812
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-5.1396	-1.4862	-6.6258	15	0	0	391	0	8	6
A-C	-30.4598	-6.8422	-148.633	-185.935	61	4	9	6684	5	22	29
A-D	-48.1604	11.8818	-180.939	-217.2176	76	11	10	8370	0	25	17
B-C	-40.5497	4.7511	-179.133	-214.9316	72	6	8	7955	0	25	17
B-D	-38.4058	-5.3496	-147.115	-190.8704	60	5	8	6805	4	23	26
C-D	0.0	-5.9368	-1.2453	-7.1821	12	0	0	310	0	8	6

Interface residues

• A-B: GLU194A, GLU194B, GLU195A, GLU195B, LYS190A, LYS190B, LYS202A, LYS202B, PRO191A, PRO191B, PRO199A, PRO199B, TYR141A, TYR203A, TYR203B
• A-C: ALA159A, ALA159C, ARG162A, ARG162C, ARG165A, ARG165C, ARG166A, ARG166C, ARG169A, ARG169C, ARG210A, ARG210C, ASP158A, ASP158C, ASP160A, ASP160C, ASP170C, ASP177A, ASP177C, GLN180A, GLN180C, GLU179A, GLU179C, GLU194A, GLU194C, ILE171A, ILE171C, ILE181A, ILE181C, ILE186A, ILE186C, LEU163A, LEU163C, LEU168A, LEU168C, LEU178A, LEU178C, LEU182A, LEU182C, LYS190A, LYS190C, PHE193A, PHE193C, PRO191A, PRO191C, SER164A, SER164C, SER172A, SER172C, SER183A, SER183C, THR157A, THR157C, THR161A, THR161C, TYR185A, TYR185C, VAL167A, VAL167C, VAL189A, VAL189C
• A-D: ALA204A, ALA204D, ALA217A, ALA217D, ARG210A, ARG210D, ASN214A, ASN214D, ASN219A, ASN219D, ASN230A, ASN230D, ASP156A, ASP156D, ASP158A, ASP158D, ASP205A, ASP205D, ASP227A, ASP227D, GLN150A, GLN150D, GLN223A, GLN223D, GLN226A, GLN226D, GLY211A, GLY211D, HIS224A, HIS224D, ILE207A, ILE207D, ILE208A, ILE208D, ILE218A, ILE218D, ILE221A, ILE221D, ILE225A, ILE225D, ILE228A, ILE228D, ILE23A, ILE23D, LEU153A, LEU153D, LEU215A, LEU215D, LEU220A, LEU220D, LEU229A, LEU229D, LYS152A, LYS152D, LYS201A, LYS201D, LYS202A, LYS202D, MET151A, MET151D, PHE149A, PHE149D, PHE154A, PHE154D, PHE21A, PHE21D, PRO209A, PRO209D, TYR203A, TYR203D, VAL206A, VAL206D, VAL216A, VAL216D, VAL222A, VAL222D
• B-C: ALA204B, ALA204C, ALA217B, ALA217C, ARG210B, ARG210C, ASN214B, ASN214C, ASN219B, ASN219C, ASP156B, ASP156C, ASP158B, ASP158C, ASP205B, ASP205C, ASP227B, ASP227C, GLN150B, GLN150C, GLN223B, GLN223C, GLN226B, GLN226C, GLY211B, GLY211C, HIS224B, HIS224C, ILE207B, ILE207C, ILE208B, ILE208C, ILE218B, ILE218C, ILE221B, ILE221C, ILE225B, ILE225C, ILE228B, ILE228C, ILE23B, ILE23C, LEU153B, LEU153C, LEU215B, LEU215C, LEU220B, LEU220C, LYS152B, LYS152C, LYS201B, LYS201C, LYS202B, LYS202C, MET151B, MET151C, PHE149B, PHE149C, PHE154B, PHE154C, PHE21B, PHE21C, PRO209B, PRO209C, TYR203B, TYR203C, VAL206B, VAL206C, VAL216B, VAL216C, VAL222B, VAL222C
• B-D: ALA159B, ALA159D, ARG162B, ARG162D, ARG165B, ARG165D, ARG166B, ARG166D, ARG169B, ARG169D, ARG210B, ARG210D, ASP158B, ASP158D, ASP160B, ASP160D, ASP170D, ASP177D, GLN180B, GLN180D, GLU179B, GLU179D, GLU194B, GLU194D, ILE171B, ILE171D, ILE181B, ILE181D, ILE186B, ILE186D, LEU163B, LEU163D, LEU168B, LEU168D, LEU178B, LEU178D, LEU182B, LEU182D, LYS190B, LYS190D, PHE193B, PHE193D, PRO191B, PRO191D, SER164B, SER164D, SER172B, SER172D, SER183B, SER183D, THR157B, THR157D, THR161B, THR161D, TYR185B, TYR185D, VAL167B, VAL167D, VAL189B, VAL189D
• C-D: GLU194C, GLU194D, GLU195C, GLU195D, LYS190C, LYS190D, LYS202C, LYS202D, PRO191C, PRO191D, PRO199C, PRO199D