1U76

crystal structure of hpcna bound to residues 452-466 of the dna polymerase-delta-p66 subunit

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 61
  • Norm. En. per Res.: -5.2135
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-36.1338	0.0	-231.318	-267.4518	58	19	12	8676	0	4	3
A-C	-83.4922	14.8506	-194.965	-263.6066	74	12	1	8064	0	27	32
A-E	-73.3459	15.7261	-190.697	-248.3167	74	7	1	7880	0	28	32
C-D	-52.0382	-16.5691	-249.415	-318.0223	61	22	12	9499	0	6	4
C-E	-81.1537	15.5395	-186.576	-252.1902	74	9	1	7764	0	27	30
E-F	-37.508	-35.0826	-241.727	-314.3176	64	25	14	9502	2	8	4

Interface residues

• A-B: ALA157A, ALA208A, ALA231A, ALA252A, ALA453B, ARG210A, ARG455B, ASN454B, ASP232A, ASP257A, ASP41A, GLN125A, GLN131A, GLN204A, GLN38A, GLN456B, GLN464B, GLU124A, GLU256A, GLY127A, GLY461B, HIS44A, ILE128A, ILE255A, ILE459B, LEU126A, LEU205A, LEU235A, LEU251A, LEU47A, LYS254A, MET40A, PHE207A, PHE215A, PHE462B, PHE463B, PRO129A, PRO234A, PRO253A, SER230A, SER39A, SER42A, SER43A, SER458B, SER46A, THR206A, THR460B, TYR133A, TYR211A, TYR249A, TYR250A, VAL158A, VAL159A, VAL233A, VAL236A, VAL457B, VAL45A, VAL48A
• A-C: ALA100A, ALA105A, ALA171C, ALA194C, ALA82A, ARG146C, ARG149C, ASN107A, ASN177C, ASN179C, ASN71A, ASN84A, ASP113A, ASP150C, ASP86A, CYS148C, CYS81A, GLN108A, GLN184C, GLU109A, GLU115A, GLU143C, GLU174C, GLU193C, GLU85A, GLY142C, GLY155C, GLY166C, GLY173C, GLY176C, GLY178C, GLY83A, HIS153C, ILE147C, ILE154C, ILE180C, ILE78A, LEU101A, LEU118A, LEU151C, LEU175C, LEU182C, LEU79A, LEU99A, LYS110A, LYS117A, LYS13A, LYS168C, LYS181C, LYS77A, LYS80A, MET116A, MET119A, MET139C, MET75A, PHE103A, PHE144C, PHE169C, PRO140C, SER112A, SER152C, SER170C, SER172C, SER183C, SER74A, SER76A, THR185C, THR73A, THR98A, TYR114A, VAL102A, VAL111A, VAL167C, VAL195C
• A-E: ALA100E, ALA105E, ALA145A, ALA171A, ALA194A, ALA82E, ARG146A, ARG149A, ASN107E, ASN177A, ASN179A, ASN71E, ASN84E, ASP113E, ASP150A, ASP86E, CYS148A, CYS81E, GLN108E, GLN184A, GLU109E, GLU115E, GLU143A, GLU174A, GLU193A, GLU85E, GLY142A, GLY155A, GLY173A, GLY176A, GLY178A, GLY83E, HIS153A, ILE147A, ILE154A, ILE180A, ILE78E, LEU101E, LEU151A, LEU175A, LEU182A, LEU79E, LEU99E, LYS110E, LYS117E, LYS13E, LYS168A, LYS181A, LYS77E, LYS80E, MET116E, MET119E, MET139A, MET75E, PHE103E, PHE144A, PHE169A, PRO140A, SER112E, SER152A, SER170A, SER172A, SER183A, SER186A, SER74E, SER76E, THR185A, THR73E, THR98E, TYR114E, VAL102E, VAL111E, VAL167A, VAL195A
• C-D: ALA157C, ALA208C, ALA231C, ALA252C, ALA453D, ARG210C, ARG455D, ARG465D, ASN454D, ASP122C, ASP156C, ASP232C, ASP257C, ASP41C, GLN125C, GLN131C, GLN204C, GLN38C, GLN456D, GLN464D, GLN49C, GLU124C, GLU256C, GLY127C, GLY461D, HIS44C, ILE128C, ILE255C, ILE459D, LEU126C, LEU205C, LEU235C, LEU251C, LEU47C, LYS254C, MET40C, PHE207C, PHE215C, PHE462D, PHE463D, PRO129C, PRO234C, PRO253C, SER39C, SER42C, SER43C, SER458D, SER46C, THR206C, THR460D, TYR133C, TYR211C, TYR249C, TYR250C, VAL123C, VAL159C, VAL233C, VAL236C, VAL457D, VAL45C, VAL48C
• C-E: ALA100C, ALA105C, ALA145E, ALA171E, ALA194E, ALA82C, ARG146E, ARG149E, ASN107C, ASN177E, ASN179E, ASN71C, ASN84C, ASP113C, ASP150E, ASP86C, CYS148E, CYS81C, GLN184E, GLU109C, GLU115C, GLU143E, GLU174E, GLU193E, GLU85C, GLY142E, GLY155E, GLY166E, GLY173E, GLY176E, GLY178E, GLY83C, HIS153E, ILE147E, ILE154E, ILE180E, ILE78C, LEU101C, LEU151E, LEU175E, LEU182E, LEU79C, LEU99C, LYS110C, LYS117C, LYS13C, LYS168E, LYS181E, LYS77C, LYS80C, MET116C, MET119C, MET139E, MET75C, PHE103C, PHE144E, PHE169E, PRO140E, SER112C, SER152E, SER170E, SER172E, SER183E, SER186E, SER74C, SER76C, THR185E, THR73C, THR98C, TYR114C, VAL102C, VAL111C, VAL167E, VAL195E
• E-F: ALA157E, ALA208E, ALA231E, ALA252E, ALA453F, ARG210E, ARG455F, ARG465F, ASN454F, ASP156E, ASP232E, ASP257E, ASP41E, GLN125E, GLN131E, GLN204E, GLN38E, GLN456F, GLN464F, GLN49E, GLU124E, GLU256E, GLU258E, GLU259E, GLY127E, GLY461F, HIS44E, ILE128E, ILE160E, ILE255E, ILE459F, LEU126E, LEU205E, LEU235E, LEU251E, LEU47E, LYS254E, MET40E, PHE207E, PHE215E, PHE462F, PHE463F, PRO129E, PRO234E, PRO253E, SER230E, SER39E, SER42E, SER43E, SER458F, SER46E, THR206E, THR460F, TYR133E, TYR211E, TYR249E, TYR250E, VAL158E, VAL159E, VAL233E, VAL236E, VAL457F, VAL45E, VAL48E