1TZD

crystal structure of the catalytic core of inositol 1,4,5- trisphosphate 3-kinase

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 79
  • Norm. En. per Res.: -2.7879
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-23.2975	-61.113	-135.836	-220.2465	79	31	3	6384	5	54	57

Interface residues

• A-B: ALA292A, ALA292B, ALA336A, ALA336B, ARG317A, ARG317B, ASP254A, ASP254B, ASP285A, ASP285B, ASP294A, ASP294B, ASP337A, ASP337B, ASP343A, ASP343B, ASP403A, ASP403B, CYS257A, CYS257B, CYS340A, CYS340B, CYS405A, CYS405B, GLN362A, GLN362B, GLU302A, GLU302B, GLU331A, GLU331B, GLU359A, GLU359B, GLY255A, GLY255B, GLY332A, GLY332B, GLY338A, GLY338B, HIS402B, HIS404A, HIS404B, ILE320B, ILE333A, ILE333B, LEU291A, LEU291B, LYS284A, LYS288A, LYS288B, LYS289A, LYS289B, LYS334A, LYS334B, LYS335A, LYS335B, LYS345A, LYS345B, PHE253A, PHE253B, PHE344A, PHE344B, PRO256A, PRO256B, PRO295A, PRO295B, SER339A, SER339B, SER341A, SER341B, THR342A, THR342B, THR346A, THR346B, TRP316A, TRP316B, TYR313A, TYR313B, VAL293A, VAL293B