1TPK

crystal structure of the kringle-2 domain of tissue plasminogen activator at 2.4-angstroms resolution

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 53
  • Norm. En. per Res.: -2.4512
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-17.6382	-25.993	-64.2919	-107.9231	49	2	0	3107	3	6	11
B-C	-29.4575	-23.102	-77.3543	-129.9139	53	3	0	3396	3	7	13

Interface residues

• A-C: ALA37C, ALA58A, ARG52A, ARG70A, ASN-2C, ASN26C, ASN39A, ASN49C, ASN53A, ASP55A, ASP57A, CYS22C, CYS63A, GLN38C, GLN42C, GLU73A, GLY-3C, GLY32A, GLY47C, GLY56A, HIS48C, HIS64A, ILE29C, ILE31A, ILE31C, LEU23C, LEU30C, LEU44A, LEU70A, LYS33A, LYS47C, LYS60A, MET28C, PRO24C, PRO40A, PRO54A, SER21C, SER27C, SER41A, THR12C, THR71A, TRP25A, TRP25C, TRP62A, TRP72A, TYR35A, TYR50C, TYR74A, VAL34A
• B-C: ALA37B, ALA42C, ALA58C, ARG10B, ARG52B, ARG52C, ARG70C, ASN26B, ASN39C, ASN49B, ASN53C, ASP55C, ASP57C, CYS22B, CYS63C, GLN38B, GLN42B, GLU73C, GLY-3B, GLY11B, GLY32C, GLY47B, GLY56C, HIS48B, HIS64C, ILE29B, ILE31B, LEU23B, LEU30B, LEU44C, LEU46C, LEU70C, LYS33C, LYS47B, LYS60C, MET28B, PRO24B, PRO40C, PRO54C, SER-1B, SER27B, SER41C, THR12B, THR36C, THR71C, TRP25B, TRP25C, TRP62C, TRP72C, TYR35C, TYR50B, TYR74C, VAL34C