1TC2

ternary substrate complex of the hypoxanthine phosphoribosyltransferase from trypanosoma cruzi

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 153
  • Norm. En. per Res.: -4.1953
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-75.2663	-112.522	-454.085	-641.8733	153	17	11	17860	16	76	57

Interface residues

• A-B: ALA26A, ALA526B, ALA559B, ALA564B, ALA59A, ALA64A, ALA696B, ARG177A, ARG180A, ARG19A, ARG39A, ARG503B, ARG519B, ARG539B, ARG563B, ARG573B, ARG599B, ARG63A, ARG677B, ARG680B, ARG693B, ARG697B, ARG73A, ARG93A, ARG99A, ASN43A, ASN569B, ASN69A, ASP171A, ASP173A, ASP174A, ASP181A, ASP560B, ASP567B, ASP597B, ASP60A, ASP671B, ASP673B, ASP674B, ASP67A, ASP681B, ASP97A, CYS562B, CYS566B, CYS578B, CYS62A, CYS66A, CYS78A, GLU15A, GLU178A, GLU504B, GLU515B, GLU575B, GLU584B, GLU678B, GLU692B, GLU75A, GLY167A, GLY169A, GLY53A, GLY553B, GLY583B, GLY669B, HIS100A, HIS600B, ILE166A, ILE18A, ILE22A, ILE518B, ILE522B, ILE577B, ILE666B, ILE77A, LEU179A, LEU185A, LEU45A, LEU47A, LEU51A, LEU545B, LEU547B, LEU551B, LEU561B, LEU565B, LEU595B, LEU596B, LEU61A, LEU65A, LEU679B, LEU685B, LEU95A, LEU96A, LYS23A, LYS523B, LYS52A, LYS552B, MET556B, MET56A, MET574B, MET594B, MET74A, MET94A, PHE507B, PHE555B, PHE557B, PHE55A, PHE568B, PHE576B, PHE57A, PHE68A, PHE76A, PHE7A, PRO40A, PRO44A, PRO540B, PRO544B, PRO571B, PRO71A, SER49A, SER549B, SER54A, SER554B, SER580B, SER80A, THR175A, THR558B, THR58A, THR598B, THR675B, THR98A, TYR168A, TYR172A, TYR176A, TYR190A, TYR41A, TYR505B, TYR541B, TYR5A, TYR668B, TYR672B, TYR676B, TYR690B, VAL189A, VAL42A, VAL46A, VAL542B, VAL546B, VAL570B, VAL572B, VAL579B, VAL689B, VAL70A, VAL72A, VAL79A