1T2K

structure of the dna binding domains of irf3, atf-2 and jun bound to dna

• Total interactions analyzed: 15
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 85
  • Norm. En. per Res.: -2.2218
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	0.0	0.0	-0.1614	-0.1614	11	0	0	63	0	5	5
A-D	0.0	1.8243	-29.2404	-27.4161	19	2	0	1332	1	13	21
B-C	0.0	0.7672	-3.1709	-2.4037	11	0	0	305	0	6	11
C-D	-4.1461	-2.2787	-182.426	-188.8508	85	23	22	9975	1	21	24

Interface residues

• A-C: ALA255C, ARG259C, ARG78A, ASP72A, GLU256C, LYS254C, LYS258C, LYS70A, PRO71A, PRO74A, THR75A
• A-D: ALA346D, ALA46A, ARG337D, ARG338D, ARG345D, ARG352D, ARG43A, ASP45A, GLN44A, GLU342D, HIS101A, HIS40A, LEU341D, LEU42A, LYS339D, LYS39A, LYS98A, PRO100A, SER349D
• B-C: ARG257C, ARG261C, ARG43B, ARG96B, ASP95B, ASP99B, HIS101B, LYS254C, LYS258C, LYS98B, PRO100B
• C-D: ALA278C, ALA289C, ALA295C, ALA298C, ALA306C, ALA366D, ALA388D, ALA396D, ARG270C, ARG276C, ARG279C, ARG302C, ARG352D, ARG355D, ARG384D, ASN291C, ASN299C, ASN314C, ASN373D, ASN385D, ASP368D, GLN290C, GLN304C, GLN307C, GLN310C, GLN360D, GLN375D, GLN377D, GLN389D, GLN392D, GLU275C, GLU281C, GLU282C, GLU293C, GLU303C, GLU363D, GLU367D, GLU379D, GLU386D, GLY374D, ILE277C, LEU274C, LEU280C, LEU287C, LEU294C, LEU301C, LEU308C, LEU362D, LEU369D, LEU372D, LEU376D, LEU382D, LEU383D, LEU390D, LEU393D, LEU394D, LEU395D, LYS273C, LYS283C, LYS285C, LYS288C, LYS309C, LYS311C, LYS356D, LYS364D, LYS365D, LYS391D, MET300C, MET313C, SER292C, SER296C, SER361D, SER370D, SER371D, SER378D, THR286C, THR297C, THR381D, TRP358D, VAL284C, VAL305C, VAL312C, VAL359D, VAL380D, VAL387D