1SX3

groel14-(atpgammas)14

• Total interactions analyzed: 91
• Total true interactions: 29
• Strongest Interaction:
  • Chains: A-G
  • Int. Res.: 179
  • Norm. En. per Res.: -3.122
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-92.0449	-30.7629	-345.196	-468.0038	174	19	8	14905	5	73	74
A-G	-118.4404	-47.5736	-392.823	-558.837	179	41	9	16466	8	80	79
A-L	0.0	1.0706	-32.8531	-31.7825	22	1	1	1393	0	6	5
A-M	0.0	0.0	-17.6095	-17.6095	21	1	4	1087	0	4	3
B-C	-107.4992	-54.2598	-392.361	-554.1199	180	19	9	16412	7	82	77
B-G	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	0
B-K	0.0	1.0761	-31.8828	-30.8067	22	0	1	1359	0	6	5
B-L	0.0	0.0	-15.5278	-15.5278	28	0	5	1115	0	15	10
C-D	-102.5031	-40.9677	-350.654	-494.1247	172	24	8	15213	6	74	72
C-J	-6.0441	1.0288	-33.695	-38.7103	22	2	1	1452	0	6	5
C-K	0.0	0.0	-17.8272	-17.8272	30	1	6	1198	0	16	10
D-E	-106.6543	-53.1655	-401.89	-561.7098	185	21	8	16617	9	80	81
D-F	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
D-I	0.0	1.0774	-30.9027	-29.8253	22	0	1	1371	0	6	5
D-J	0.0	0.0	-13.0058	-13.0058	26	1	3	953	0	11	8
E-F	-93.5495	-49.8796	-362.922	-506.3511	180	14	8	15534	5	76	74
E-H	0.0	1.0454	-33.5269	-32.4815	22	1	1	1459	0	6	5
E-I	0.0	0.0	-18.2005	-18.2005	28	0	3	1166	0	16	11
F-G	-91.8314	-40.214	-338.139	-470.1843	173	21	8	14941	4	75	76
F-H	0.0	0.0	-18.4875	-18.4875	29	1	5	1215	0	15	11
F-N	0.0	1.0477			2
G-M	0.0	1.0724	0.0	1.0724	2	0	0	0	0	0	0
H-I	-102.8668	-46.1488	-371.995	-521.0106	180	14	10	15941	7	82	84
H-N	-122.7759	-51.754			35
I-J	-109.1497	-51.7093	-372.983	-533.842	181	18	9	15691	6	80	77
J-K	-103.8396	-47.5631	-375.525	-526.9277	182	16	9	15938	5	81	79
K-L	-81.7315	-44.6879	-319.516	-445.9354	171	11	8	14532	6	77	75
L-M	-119.4546	-46.5302	-249.25	-415.2349	158	14	4	10691	6	68	64
M-N	-93.0068	-45.7501			36

Interface residues

• A-B: ALA12B, ALA241A, ALA243A, ALA24A, ALA258B, ALA26A, ALA278B, ALA2B, ALA383A, ALA384A, ALA3B, ALA46A, ALA480A, ALA481A, ALA57A, ALA71B, ARG118B, ARG18A, ARG197B, ARG231B, ARG268A, ARG284B, ARG285B, ARG36A, ARG58A, ASN112B, ASN206A, ASN21A, ASN229B, ASN265A, ASN37A, ASN433B, ASN457A, ASN68A, ASN68B, ASP115B, ASP179A, ASP196B, ASP25A, ASP283B, ASP359B, ASP361B, ASP41A, ASP523B, ASP5B, ASP64A, CYS458A, CYS519B, GLN184A, GLN432B, GLN436B, GLN453A, GLN72A, GLN72B, GLU214A, GLU216A, GLU232B, GLU238A, GLU252B, GLU255B, GLU257B, GLU303B, GLU308B, GLU367B, GLU386A, GLU460A, GLU483A, GLU518B, GLU59A, GLU61A, GLU63A, GLU76B, GLY180A, GLY182A, GLY244A, GLY256B, GLY269A, GLY280B, GLY282B, GLY32A, GLY35A, GLY382A, GLY459A, GLY45A, GLY512B, GLY70B, GLY9B, ILE227B, ILE230B, ILE270A, ILE49A, ILE515B, ILE60A, LEU116B, LEU183A, LEU23A, LEU40A, LEU456A, LEU513B, LEU524B, LEU62A, LYS117B, LYS207A, LYS225B, LYS226B, LYS242A, LYS245A, LYS272A, LYS277B, LYS28A, LYS34A, LYS364B, LYS390A, LYS42A, LYS4B, LYS51A, LYS526B, LYS65A, LYS65B, LYS75A, LYS75B, LYS7B, LYS80B, MET111B, MET114B, MET16B, MET267A, MET389A, MET514B, MET520B, MET69B, MET73B, PHE281B, PHE44A, PHE66B, PHE8B, PRO113B, PRO279B, PRO33A, PRO47A, PRO525B, SER228B, SER358B, SER43A, SER509B, SER55A, SER79B, THR181A, THR266A, THR30A, THR385A, THR482A, THR48A, THR50A, THR516B, THR517B, THR522B, TYR203B, TYR360B, VAL107B, VAL22A, VAL271A, VAL27A, VAL29A, VAL381A, VAL387A, VAL38A, VAL39A, VAL455A, VAL510B, VAL521B, VAL56A, VAL6B, VAL74B
• A-G: ALA12A, ALA239G, ALA241G, ALA243G, ALA24G, ALA258A, ALA260A, ALA26G, ALA278A, ALA2A, ALA383G, ALA384G, ALA3A, ALA46G, ALA480G, ALA481G, ALA57G, ALA71A, ARG118A, ARG18G, ARG197A, ARG231A, ARG268G, ARG284A, ARG285A, ARG322G, ARG36G, ARG58G, ASN112A, ASN206G, ASN21G, ASN229A, ASN37G, ASN433A, ASN457G, ASN68A, ASN68G, ASP115A, ASP179G, ASP196A, ASP25G, ASP283A, ASP361A, ASP41G, ASP523A, ASP5A, ASP64G, CYS458G, CYS519A, GLN184G, GLN432A, GLN436A, GLN453G, GLN72A, GLN72G, GLU186G, GLU214G, GLU216G, GLU232A, GLU238G, GLU252A, GLU255A, GLU257A, GLU303A, GLU308A, GLU310A, GLU386G, GLU388G, GLU460G, GLU483G, GLU518A, GLU59G, GLU61A, GLU61G, GLU63G, GLU76A, GLY180G, GLY182G, GLY244G, GLY256A, GLY269G, GLY280A, GLY282A, GLY32G, GLY35G, GLY382G, GLY459G, GLY45G, GLY512A, GLY70A, GLY9A, ILE230A, ILE270G, ILE49G, ILE515A, ILE60G, LEU116A, LEU183G, LEU237G, LEU23G, LEU314G, LEU40G, LEU456G, LEU513A, LEU524A, LEU62G, LYS117A, LYS207G, LYS225A, LYS226A, LYS242G, LYS245G, LYS272G, LYS277A, LYS286A, LYS28G, LYS34G, LYS364A, LYS390G, LYS42G, LYS4A, LYS51G, LYS526A, LYS65A, LYS65G, LYS75A, LYS75G, LYS7A, LYS80A, MET111A, MET114A, MET16A, MET389G, MET514A, MET520A, MET69A, MET73A, PHE281A, PHE44G, PHE66A, PHE8A, PRO113A, PRO246G, PRO33G, PRO47G, PRO525A, SER217G, SER228A, SER358A, SER43G, SER509A, SER55G, SER79A, THR181G, THR30G, THR385G, THR482G, THR48G, THR50G, THR516A, THR517A, THR522A, TYR360A, VAL107A, VAL22G, VAL240G, VAL271G, VAL27G, VAL29G, VAL381G, VAL387G, VAL38G, VAL39G, VAL455G, VAL510A, VAL521A, VAL56G, VAL6A, VAL74A
• A-L: ALA466A, ALA466L, ARG452A, ARG452L, ASN467A, ASN467L, GLU461A, GLU461L, LYS470A, LYS470L, PRO462A, PRO462L, SER463A, SER463L, THR468A, THR468L, TYR485A, TYR485L, VAL464A, VAL464L, VAL465A, VAL465L
• A-M: ALA106A, ALA106M, ALA108A, ALA108M, ALA109A, ALA109M, ARG445A, ASN10A, ASN10M, GLU102A, GLU102M, GLY110A, GLY110M, LEU104M, LYS105A, LYS105M, MET111A, MET111M, VAL107A, VAL107M, VAL438A
• B-C: ALA12C, ALA239B, ALA241B, ALA243B, ALA24B, ALA258C, ALA260C, ALA26B, ALA278C, ALA2C, ALA383B, ALA384B, ALA3C, ALA46B, ALA480B, ALA481B, ALA57B, ALA71C, ARG118C, ARG18B, ARG197C, ARG231C, ARG268B, ARG284C, ARG285C, ARG36B, ARG58B, ASN112C, ASN206B, ASN21B, ASN229C, ASN265B, ASN37B, ASN433C, ASN457B, ASN68B, ASN68C, ASP115C, ASP179B, ASP253C, ASP25B, ASP283C, ASP361C, ASP41B, ASP523C, ASP5C, ASP64B, CYS458B, CYS519C, GLN184B, GLN432C, GLN436C, GLN453B, GLN72B, GLN72C, GLU186B, GLU214B, GLU216B, GLU232C, GLU238B, GLU252C, GLU255C, GLU257C, GLU303C, GLU308C, GLU310C, GLU386B, GLU388B, GLU460B, GLU483B, GLU518C, GLU59B, GLU61B, GLU63B, GLU76C, GLY180B, GLY182B, GLY244B, GLY256C, GLY269B, GLY280C, GLY282C, GLY32B, GLY35B, GLY382B, GLY459B, GLY45B, GLY512C, GLY70C, GLY9C, ILE227C, ILE230C, ILE270B, ILE49B, ILE515C, ILE60B, LEU116C, LEU183B, LEU237B, LEU23B, LEU40B, LEU456B, LEU513C, LEU524C, LEU62B, LYS117C, LYS207B, LYS225C, LYS226C, LYS242B, LYS245B, LYS272B, LYS277C, LYS286C, LYS28B, LYS34B, LYS364C, LYS390B, LYS42B, LYS4C, LYS51B, LYS526C, LYS65B, LYS65C, LYS75B, LYS75C, LYS7C, LYS80C, MET111C, MET114C, MET16C, MET389B, MET514C, MET520C, MET69C, MET73C, PHE281C, PHE44B, PHE66C, PHE8C, PRO113C, PRO246B, PRO279C, PRO33B, PRO47B, PRO525C, SER217B, SER228C, SER358C, SER43B, SER509C, SER55B, SER79C, THR181B, THR266B, THR30B, THR385B, THR482B, THR48B, THR50B, THR516C, THR517C, THR522C, TYR360C, VAL107C, VAL22B, VAL240B, VAL271B, VAL27B, VAL29B, VAL381B, VAL387B, VAL38B, VAL39B, VAL455B, VAL510C, VAL521C, VAL56B, VAL6C, VAL74C
• B-G: ALA2B, PHE44G
• B-K: ALA466B, ALA466K, ARG452B, ARG452K, ASN467B, ASN467K, GLU461B, GLU461K, LYS470B, LYS470K, PRO462B, PRO462K, SER463B, SER463K, THR468B, THR468K, TYR485B, TYR485K, VAL464B, VAL464K, VAL465B, VAL465K
• B-L: ALA106B, ALA106L, ALA108B, ALA108L, ALA109B, ALA109L, ARG430B, ARG430L, ARG445B, ARG445L, ASN10B, ASN10L, GLU102B, GLU102L, GLU434B, GLU434L, GLY110B, GLY110L, LYS105B, LYS105L, LYS441B, LYS441L, MET111B, MET111L, VAL107B, VAL107L, VAL438B, VAL438L
• C-D: ALA12D, ALA241C, ALA243C, ALA24C, ALA258D, ALA26C, ALA278D, ALA2D, ALA383C, ALA384C, ALA3D, ALA46C, ALA480C, ALA481C, ALA57C, ALA71D, ARG118D, ARG18C, ARG197D, ARG231D, ARG268C, ARG284D, ARG285D, ARG36C, ARG58C, ASN112D, ASN206C, ASN21C, ASN229D, ASN265C, ASN37C, ASN433D, ASN457C, ASN68C, ASN68D, ASP115D, ASP179C, ASP25C, ASP283D, ASP359D, ASP361D, ASP41C, ASP523D, ASP5D, ASP64C, CYS458C, CYS519D, GLN184C, GLN432D, GLN436D, GLN453C, GLN72C, GLN72D, GLU214C, GLU216C, GLU232D, GLU238C, GLU252D, GLU255D, GLU257D, GLU303D, GLU308D, GLU310D, GLU386C, GLU388C, GLU460C, GLU483C, GLU518D, GLU59C, GLU61C, GLU63C, GLU76D, GLY180C, GLY182C, GLY244C, GLY256D, GLY269C, GLY280D, GLY282D, GLY32C, GLY35C, GLY382C, GLY459C, GLY45C, GLY512D, GLY70D, GLY9D, ILE227D, ILE230D, ILE270C, ILE49C, ILE515D, ILE60C, LEU183C, LEU23C, LEU40C, LEU456C, LEU513D, LEU524D, LEU62C, LYS117D, LYS207C, LYS225D, LYS226D, LYS242C, LYS245C, LYS272C, LYS277D, LYS28C, LYS34C, LYS364D, LYS390C, LYS42C, LYS4D, LYS51C, LYS526D, LYS65C, LYS65D, LYS75C, LYS75D, LYS7D, LYS80D, MET111D, MET114D, MET16D, MET267C, MET389C, MET514D, MET520D, MET69D, MET73D, PHE281D, PHE44C, PHE66D, PHE8D, PRO113D, PRO33C, PRO47C, PRO525D, SER228D, SER358D, SER43C, SER509D, SER55C, SER79D, THR181C, THR266C, THR30C, THR385C, THR482C, THR48C, THR50C, THR516D, THR517D, THR522D, TYR360D, VAL107D, VAL22C, VAL271C, VAL27C, VAL29C, VAL381C, VAL387C, VAL38C, VAL39C, VAL455C, VAL510D, VAL521D, VAL56C, VAL6D, VAL74D, VAL77D
• C-J: ALA466C, ALA466J, ARG452C, ARG452J, ASN467C, ASN467J, GLU461C, GLU461J, LYS470C, LYS470J, PRO462C, PRO462J, SER463C, SER463J, THR468C, THR468J, TYR485C, TYR485J, VAL464C, VAL464J, VAL465C, VAL465J
• C-K: ALA106C, ALA106K, ALA108C, ALA108K, ALA109C, ALA109K, ARG430C, ARG430K, ARG445C, ARG445K, ASN10C, ASN10K, GLU102C, GLU102K, GLU434C, GLU434K, GLY110C, GLY110K, LEU104C, LEU104K, LYS105C, LYS105K, LYS441C, LYS441K, MET111C, MET111K, VAL107C, VAL107K, VAL438C, VAL438K
• D-E: ALA12E, ALA239D, ALA241D, ALA243D, ALA24D, ALA258E, ALA260E, ALA26D, ALA278E, ALA2E, ALA383D, ALA384D, ALA3E, ALA46D, ALA480D, ALA481D, ALA57D, ALA71E, ARG118E, ARG18D, ARG197E, ARG231E, ARG268D, ARG284E, ARG285E, ARG36D, ARG58D, ASN112E, ASN206D, ASN21D, ASN229E, ASN265D, ASN37D, ASN433E, ASN457D, ASN68D, ASN68E, ASP115E, ASP179D, ASP196E, ASP25D, ASP283E, ASP361E, ASP41D, ASP435E, ASP523E, ASP5E, ASP64D, CYS458D, CYS519E, GLN184D, GLN432E, GLN436E, GLN453D, GLN72D, GLN72E, GLU186D, GLU214D, GLU216D, GLU232E, GLU238D, GLU252E, GLU255E, GLU257E, GLU303E, GLU308E, GLU310E, GLU386D, GLU388D, GLU460D, GLU483D, GLU484D, GLU518E, GLU59D, GLU61D, GLU61E, GLU63D, GLU76E, GLY180D, GLY182D, GLY244D, GLY256E, GLY269D, GLY280E, GLY282E, GLY32D, GLY35D, GLY382D, GLY459D, GLY45D, GLY512E, GLY70E, GLY9E, ILE227E, ILE230E, ILE270D, ILE49D, ILE515E, ILE60D, LEU116E, LEU183D, LEU237D, LEU23D, LEU259E, LEU40D, LEU456D, LEU513E, LEU524E, LEU62D, LYS117E, LYS207D, LYS225E, LYS226E, LYS242D, LYS245D, LYS272D, LYS277E, LYS286E, LYS28D, LYS34D, LYS364E, LYS390D, LYS42D, LYS4E, LYS51D, LYS526E, LYS65D, LYS65E, LYS75D, LYS75E, LYS7E, LYS80E, MET111E, MET114E, MET16E, MET389D, MET514E, MET520E, MET69E, MET73E, PHE281E, PHE44D, PHE66E, PHE8E, PRO113E, PRO246D, PRO279E, PRO33D, PRO47D, PRO525E, SER217D, SER228E, SER358E, SER43D, SER509E, SER55D, SER79E, THR181D, THR261E, THR266D, THR30D, THR385D, THR482D, THR48D, THR50D, THR516E, THR517E, THR522E, TYR360E, VAL107E, VAL22D, VAL240D, VAL271D, VAL27D, VAL29D, VAL381D, VAL387D, VAL38D, VAL39D, VAL455D, VAL510E, VAL521E, VAL56D, VAL6E, VAL74E
• D-F: ALA2F, PHE44D
• D-I: ALA466D, ALA466I, ARG452D, ARG452I, ASN467D, ASN467I, GLU461D, GLU461I, LYS470D, LYS470I, PRO462D, PRO462I, SER463D, SER463I, THR468D, THR468I, TYR485D, TYR485I, VAL464D, VAL464I, VAL465D, VAL465I
• D-J: ALA106D, ALA106J, ALA108D, ALA108J, ALA109D, ALA109J, ARG430J, ARG445D, ARG445J, ASN10D, ASN10J, GLU102D, GLU102J, GLU434D, GLU434J, GLY110D, GLY110J, LYS105D, LYS105J, LYS441D, MET111D, MET111J, VAL107D, VAL107J, VAL438D, VAL438J
• E-F: ALA12F, ALA241E, ALA243E, ALA24E, ALA258F, ALA260F, ALA26E, ALA278F, ALA2F, ALA383E, ALA384E, ALA3F, ALA46E, ALA480E, ALA481E, ALA57E, ALA71F, ARG118F, ARG18E, ARG197F, ARG231F, ARG268E, ARG284F, ARG285F, ARG36E, ARG58E, ASN112F, ASN206E, ASN21E, ASN229F, ASN265E, ASN37E, ASN433F, ASN457E, ASN68E, ASN68F, ASP115F, ASP179E, ASP196F, ASP25E, ASP283F, ASP361F, ASP41E, ASP523F, ASP5F, ASP64E, CYS458E, CYS519F, GLN184E, GLN432F, GLN436F, GLN453E, GLN72E, GLN72F, GLU214E, GLU216E, GLU232F, GLU238E, GLU252F, GLU255F, GLU257F, GLU303F, GLU308F, GLU310F, GLU386E, GLU388E, GLU460E, GLU483E, GLU518F, GLU59E, GLU61E, GLU61F, GLU63E, GLU76F, GLY180E, GLY182E, GLY244E, GLY256F, GLY269E, GLY280F, GLY282F, GLY32E, GLY35E, GLY382E, GLY459E, GLY45E, GLY512F, GLY70F, GLY9F, ILE227F, ILE230F, ILE270E, ILE49E, ILE515F, ILE60E, LEU116F, LEU183E, LEU237E, LEU23E, LEU40E, LEU456E, LEU513F, LEU524F, LEU62E, LYS117F, LYS207E, LYS225F, LYS226F, LYS242E, LYS245E, LYS272E, LYS277F, LYS286F, LYS28E, LYS34E, LYS364F, LYS390E, LYS42E, LYS4F, LYS51E, LYS526F, LYS65E, LYS65F, LYS75E, LYS75F, LYS7F, LYS80F, MET111F, MET114F, MET16F, MET267E, MET389E, MET514F, MET520F, MET69F, MET73F, PHE281F, PHE44E, PHE66F, PHE8F, PRO113F, PRO246E, PRO279F, PRO33E, PRO47E, PRO525F, SER228F, SER358F, SER43E, SER509F, SER55E, SER79F, THR181E, THR266E, THR30E, THR385E, THR482E, THR48E, THR50E, THR516F, THR517F, THR522F, TYR360F, VAL107F, VAL22E, VAL240E, VAL271E, VAL27E, VAL29E, VAL381E, VAL387E, VAL38E, VAL39E, VAL455E, VAL510F, VAL521F, VAL56E, VAL6F, VAL74F, VAL77F
• E-H: ALA466E, ALA466H, ARG452E, ARG452H, ASN467E, ASN467H, GLU461E, GLU461H, LYS470E, LYS470H, PRO462E, PRO462H, SER463E, SER463H, THR468E, THR468H, TYR485E, TYR485H, VAL464E, VAL464H, VAL465E, VAL465H
• E-I: ALA106E, ALA106I, ALA108E, ALA108I, ALA109E, ALA109I, ARG430E, ARG430I, ARG445E, ARG445I, ASN10E, ASN10I, GLU102E, GLU102I, GLU434E, GLU434I, GLY110E, GLY110I, LYS105E, LYS105I, LYS441E, LYS441I, MET111E, MET111I, VAL107E, VAL107I, VAL438E, VAL438I
• F-G: ALA12G, ALA241F, ALA243F, ALA24F, ALA258G, ALA26F, ALA2G, ALA383F, ALA384F, ALA3G, ALA46F, ALA480F, ALA481F, ALA57F, ALA71G, ARG118G, ARG18F, ARG197G, ARG231G, ARG268F, ARG284G, ARG285G, ARG36F, ARG58F, ASN112G, ASN206F, ASN21F, ASN229G, ASN265F, ASN37F, ASN433G, ASN457F, ASN68F, ASN68G, ASP115G, ASP179F, ASP25F, ASP283G, ASP359G, ASP361G, ASP41F, ASP523G, ASP5G, ASP64F, CYS458F, CYS519G, GLN184F, GLN432G, GLN436G, GLN453F, GLN72F, GLN72G, GLU216F, GLU232G, GLU238F, GLU252G, GLU255G, GLU257G, GLU303G, GLU304G, GLU308G, GLU386F, GLU388F, GLU460F, GLU483F, GLU518G, GLU59F, GLU61F, GLU63F, GLU76G, GLY180F, GLY182F, GLY244F, GLY256G, GLY269F, GLY280G, GLY282G, GLY306G, GLY32F, GLY35F, GLY382F, GLY459F, GLY45F, GLY512G, GLY70G, GLY9G, ILE227G, ILE230G, ILE270F, ILE49F, ILE515G, ILE60F, LEU183F, LEU23F, LEU40F, LEU456F, LEU513G, LEU524G, LEU62F, LYS117G, LYS207F, LYS225G, LYS226G, LYS242F, LYS245F, LYS272F, LYS277G, LYS28F, LYS34F, LYS364G, LYS390F, LYS42F, LYS4G, LYS51F, LYS526G, LYS65F, LYS65G, LYS75F, LYS75G, LYS7G, LYS80G, MET111G, MET114G, MET16G, MET267F, MET389F, MET514G, MET520G, MET69G, MET73G, PHE281G, PHE44F, PHE66G, PHE8G, PRO113G, PRO33F, PRO47F, PRO525G, SER228G, SER358G, SER43F, SER509G, SER55F, SER79G, THR181F, THR266F, THR30F, THR357G, THR385F, THR482F, THR48F, THR50F, THR516G, THR517G, THR522G, TYR203G, TYR360G, VAL107G, VAL22F, VAL271F, VAL27F, VAL29F, VAL381F, VAL387F, VAL38F, VAL39F, VAL455F, VAL510G, VAL521G, VAL56F, VAL6G, VAL74G, VAL77G
• F-H: ALA106F, ALA106H, ALA108F, ALA108H, ALA109F, ALA109H, ARG430F, ARG430H, ARG445F, ARG445H, ASN10F, ASN10H, GLU102F, GLU102H, GLU434F, GLU434H, GLY110F, GLY110H, LEU104F, LYS105F, LYS105H, LYS441F, LYS441H, MET111F, MET111H, VAL107F, VAL107H, VAL438F, VAL438H
• F-N: GLU461F, GLU461N
• G-M: GLU461G, GLU461M
• H-I: ALA12I, ALA239H, ALA241H, ALA243H, ALA24H, ALA258I, ALA260I, ALA26H, ALA278I, ALA2I, ALA383H, ALA384H, ALA3I, ALA46H, ALA480H, ALA481H, ALA57H, ALA71I, ARG118I, ARG18H, ARG197I, ARG231I, ARG268H, ARG284I, ARG285I, ARG36H, ARG58H, ASN112I, ASN206H, ASN21H, ASN229I, ASN37H, ASN433I, ASN457H, ASN68H, ASN68I, ASP115I, ASP179H, ASP196I, ASP25H, ASP283I, ASP361I, ASP41H, ASP523I, ASP5I, ASP64H, CYS458H, CYS519I, GLN184H, GLN432I, GLN436I, GLN453H, GLN72H, GLN72I, GLU186H, GLU214H, GLU216H, GLU232I, GLU238H, GLU252I, GLU255I, GLU257I, GLU303I, GLU308I, GLU310I, GLU386H, GLU388H, GLU460H, GLU483H, GLU484H, GLU518I, GLU59H, GLU61H, GLU61I, GLU63H, GLU76I, GLY180H, GLY182H, GLY244H, GLY256I, GLY269H, GLY280I, GLY282I, GLY32H, GLY35H, GLY382H, GLY459H, GLY45H, GLY512I, GLY70I, GLY9I, ILE227I, ILE230I, ILE270H, ILE49H, ILE515I, ILE60H, LEU183H, LEU237H, LEU23H, LEU40H, LEU456H, LEU513I, LEU524I, LEU62H, LYS117I, LYS207H, LYS225I, LYS226I, LYS242H, LYS245H, LYS272H, LYS277I, LYS286I, LYS28H, LYS34H, LYS364I, LYS390H, LYS42H, LYS4I, LYS51H, LYS526I, LYS65H, LYS65I, LYS75I, LYS7I, LYS80I, MET111I, MET114I, MET16I, MET267H, MET389H, MET514I, MET520I, MET69I, MET73I, PHE281I, PHE44H, PHE66I, PHE8I, PRO113I, PRO246H, PRO279I, PRO33H, PRO47H, PRO525I, SER217H, SER228I, SER358I, SER43H, SER509I, SER55H, SER79I, THR181H, THR266H, THR30H, THR385H, THR482H, THR48H, THR50H, THR516I, THR517I, THR522I, TYR360I, VAL107I, VAL22H, VAL240H, VAL271H, VAL27H, VAL29H, VAL381H, VAL387H, VAL38H, VAL39H, VAL455H, VAL510I, VAL521I, VAL56H, VAL6I, VAL74I
• H-N: ALA2H, ARG197H, ARG231H, ARG285H, ARG36N, ASN112H, ASN37N, ASP25N, ASP283H, ASP41N, ASP523H, ASP5H, CYS458N, CYS519H, GLU216N, GLU255H, GLU257H, GLU310H, GLU386N, GLU518H, GLU59N, GLU61N, GLU63N, LYS226H, LYS242N, LYS272N, LYS277H, LYS4H, LYS526H, LYS65H, THR181N, THR516H, THR522H, VAL39N, VAL521H
• I-J: ALA12J, ALA239I, ALA241I, ALA243I, ALA24I, ALA258J, ALA260J, ALA26I, ALA278J, ALA2J, ALA383I, ALA384I, ALA3J, ALA46I, ALA480I, ALA481I, ALA57I, ALA71J, ARG118J, ARG18I, ARG197J, ARG231J, ARG268I, ARG284J, ARG285J, ARG36I, ARG58I, ASN112J, ASN206I, ASN21I, ASN229J, ASN265I, ASN37I, ASN433J, ASN457I, ASN68I, ASN68J, ASP115J, ASP179I, ASP25I, ASP283J, ASP361J, ASP41I, ASP523J, ASP5J, ASP64I, CYS458I, CYS519J, GLN184I, GLN432J, GLN436J, GLN453I, GLN72I, GLN72J, GLU186I, GLU214I, GLU216I, GLU232J, GLU238I, GLU252J, GLU255J, GLU257J, GLU303J, GLU308J, GLU310J, GLU386I, GLU388I, GLU460I, GLU483I, GLU518J, GLU59I, GLU61I, GLU61J, GLU63I, GLU76J, GLY180I, GLY182I, GLY244I, GLY256J, GLY269I, GLY280J, GLY282J, GLY32I, GLY35I, GLY382I, GLY459I, GLY45I, GLY512J, GLY70J, GLY9J, ILE227J, ILE230J, ILE270I, ILE49I, ILE515J, ILE60I, LEU116J, LEU183I, LEU237I, LEU23I, LEU40I, LEU456I, LEU513J, LEU524J, LEU62I, LYS117J, LYS207I, LYS225J, LYS226J, LYS242I, LYS245I, LYS272I, LYS277J, LYS286J, LYS28I, LYS34I, LYS364J, LYS390I, LYS42I, LYS4J, LYS51I, LYS526J, LYS65I, LYS65J, LYS75I, LYS75J, LYS7J, LYS80J, MET111J, MET114J, MET16J, MET267I, MET389I, MET514J, MET520J, MET69J, MET73J, PHE281J, PHE44I, PHE66J, PHE8J, PRO113J, PRO246I, PRO279J, PRO33I, PRO47I, PRO525J, SER228J, SER358J, SER43I, SER509J, SER55I, SER79J, THR181I, THR266I, THR30I, THR385I, THR482I, THR48I, THR50I, THR516J, THR517J, THR522J, TYR360J, VAL107J, VAL22I, VAL240I, VAL271I, VAL27I, VAL29I, VAL381I, VAL387I, VAL38I, VAL39I, VAL455I, VAL510J, VAL521J, VAL56I, VAL6J, VAL74J, VAL77J
• J-K: ALA12K, ALA241J, ALA243J, ALA24J, ALA258K, ALA260K, ALA26J, ALA278K, ALA2K, ALA383J, ALA384J, ALA3K, ALA46J, ALA480J, ALA481J, ALA57J, ALA71K, ARG118K, ARG18J, ARG197K, ARG231K, ARG268J, ARG284K, ARG285K, ARG36J, ARG58J, ASN112K, ASN206J, ASN21J, ASN229K, ASN265J, ASN37J, ASN433K, ASN457J, ASN68J, ASN68K, ASP115K, ASP179J, ASP196K, ASP25J, ASP283K, ASP361K, ASP41J, ASP523K, ASP5K, ASP64J, CYS458J, CYS519K, GLN184J, GLN432K, GLN436K, GLN453J, GLN72J, GLN72K, GLU186J, GLU214J, GLU216J, GLU232K, GLU238J, GLU252K, GLU255K, GLU257K, GLU303K, GLU308K, GLU310K, GLU367K, GLU386J, GLU388J, GLU460J, GLU483J, GLU518K, GLU59J, GLU61J, GLU61K, GLU63J, GLU76K, GLY180J, GLY182J, GLY244J, GLY256K, GLY269J, GLY280K, GLY282K, GLY32J, GLY35J, GLY382J, GLY459J, GLY45J, GLY512K, GLY70K, GLY9K, ILE227K, ILE230K, ILE270J, ILE49J, ILE515K, ILE60J, LEU116K, LEU183J, LEU237J, LEU23J, LEU40J, LEU456J, LEU513K, LEU524K, LEU62J, LYS117K, LYS207J, LYS225K, LYS226K, LYS242J, LYS245J, LYS272J, LYS277K, LYS286K, LYS28J, LYS34J, LYS364K, LYS390J, LYS42J, LYS4K, LYS51J, LYS526K, LYS65J, LYS65K, LYS75J, LYS75K, LYS7K, LYS80K, MET111K, MET114K, MET16K, MET267J, MET389J, MET514K, MET520K, MET69K, MET73K, PHE281K, PHE44J, PHE66K, PHE8K, PRO113K, PRO246J, PRO279K, PRO33J, PRO47J, PRO525K, SER228K, SER358K, SER43J, SER509K, SER55J, SER79K, THR181J, THR266J, THR30J, THR385J, THR482J, THR48J, THR50J, THR516K, THR517K, THR522K, TYR360K, VAL107K, VAL22J, VAL240J, VAL271J, VAL27J, VAL29J, VAL381J, VAL387J, VAL38J, VAL39J, VAL455J, VAL510K, VAL521K, VAL56J, VAL6K, VAL74K, VAL77K
• K-L: ALA12L, ALA241K, ALA243K, ALA24K, ALA258L, ALA26K, ALA278L, ALA2L, ALA383K, ALA384K, ALA3L, ALA46K, ALA480K, ALA481K, ALA57K, ALA71L, ARG118L, ARG18K, ARG197L, ARG231L, ARG268K, ARG284L, ARG285L, ARG36K, ARG58K, ASN112L, ASN206K, ASN21K, ASN229L, ASN37K, ASN433L, ASN457K, ASN68K, ASN68L, ASP115L, ASP179K, ASP253L, ASP25K, ASP283L, ASP361L, ASP41K, ASP523L, ASP5L, ASP64K, CYS458K, CYS519L, GLN184K, GLN432L, GLN436L, GLN453K, GLN72K, GLN72L, GLU214K, GLU216K, GLU232L, GLU238K, GLU252L, GLU255L, GLU257L, GLU303L, GLU308L, GLU386K, GLU388K, GLU460K, GLU483K, GLU518L, GLU59K, GLU61K, GLU63K, GLU76L, GLY180K, GLY182K, GLY244K, GLY269K, GLY280L, GLY282L, GLY32K, GLY35K, GLY382K, GLY459K, GLY45K, GLY512L, GLY70L, GLY9L, ILE227L, ILE230L, ILE270K, ILE49K, ILE515L, ILE60K, LEU116L, LEU183K, LEU23K, LEU40K, LEU456K, LEU513L, LEU524L, LEU62K, LYS117L, LYS207K, LYS225L, LYS226L, LYS242K, LYS245K, LYS272K, LYS277L, LYS286L, LYS28K, LYS34K, LYS364L, LYS390K, LYS42K, LYS4L, LYS51K, LYS526L, LYS65K, LYS65L, LYS75K, LYS75L, LYS7L, LYS80L, MET111L, MET114L, MET16L, MET267K, MET389K, MET514L, MET520L, MET69L, MET73L, PHE281L, PHE44K, PHE66L, PHE8L, PRO113L, PRO279L, PRO33K, PRO47K, PRO525L, SER228L, SER358L, SER43K, SER509L, SER55K, SER79L, THR181K, THR30K, THR385K, THR482K, THR48K, THR50K, THR516L, THR517L, THR522L, TYR203L, TYR360L, VAL107L, VAL22K, VAL271K, VAL27K, VAL29K, VAL381K, VAL387K, VAL38K, VAL39K, VAL455K, VAL510L, VAL521L, VAL56K, VAL6L, VAL74L
• L-M: ALA12M, ALA239L, ALA241L, ALA243L, ALA24L, ALA258M, ALA260M, ALA26L, ALA278M, ALA2M, ALA383L, ALA384L, ALA3M, ALA46L, ALA480L, ALA481L, ALA57L, ALA71M, ARG118M, ARG18L, ARG197M, ARG231M, ARG268L, ARG284M, ARG285M, ARG36L, ARG58L, ASN112M, ASN21L, ASN229M, ASN37L, ASN457L, ASN68L, ASN68M, ASP115M, ASP179L, ASP196M, ASP25L, ASP283M, ASP361M, ASP41L, ASP523M, ASP5M, ASP64L, CYS458L, CYS519M, GLN184L, GLN72L, GLN72M, GLU186L, GLU214L, GLU216L, GLU232M, GLU238L, GLU252M, GLU255M, GLU257M, GLU303M, GLU308M, GLU310M, GLU386L, GLU388L, GLU460L, GLU483L, GLU518M, GLU59L, GLU61L, GLU61M, GLU63L, GLU76M, GLY180L, GLY182L, GLY244L, GLY256M, GLY269L, GLY280M, GLY282M, GLY32L, GLY35L, GLY382L, GLY459L, GLY45L, GLY70M, GLY9M, ILE230M, ILE270L, ILE49L, ILE60L, LEU183L, LEU237L, LEU23L, LEU40L, LEU456L, LEU62L, LYS117M, LYS207L, LYS225M, LYS226M, LYS242L, LYS245L, LYS272L, LYS277M, LYS286M, LYS28L, LYS34L, LYS364M, LYS390L, LYS42L, LYS4M, LYS51L, LYS526M, LYS65L, LYS65M, LYS75L, LYS75M, LYS7M, LYS80M, MET111M, MET114M, MET16M, MET389L, MET69M, MET73M, PHE281M, PHE44L, PHE66M, PHE8M, PRO113M, PRO246L, PRO279M, PRO33L, PRO47L, SER228M, SER358M, SER43L, SER79M, THR181L, THR385L, THR482L, THR48L, THR516M, THR522M, TYR360M, VAL107M, VAL22L, VAL240L, VAL271L, VAL27L, VAL29L, VAL381L, VAL387L, VAL38L, VAL39L, VAL455L, VAL521M, VAL56L, VAL6M, VAL74M
• M-N: ALA2N, ARG197N, ARG268M, ARG285N, ARG36M, ASN112N, ASN229N, ASN37M, ASP115N, ASP25M, ASP41M, ASP523N, ASP5N, CYS458M, CYS519N, GLU216M, GLU257N, GLU303N, GLU308N, GLU386M, GLU518N, GLU59M, GLU61M, GLU63M, GLY269M, LYS226N, LYS242M, LYS245M, LYS34M, LYS4N, LYS526N, LYS65N, THR516N, THR522N, VAL39M, VAL521N