1SOJ

catalytic domain of human phosphodiesterase 3b in complex with ibmx

• Total interactions analyzed: 66
• Total true interactions: 24
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 98
  • Norm. En. per Res.: -3.4549
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.5509	-109.0289	-197.62	-319.1997	99	19	7	8717	8	18	16
A-C	0.0	-3.5781	-59.1075	-62.6856	70	7	0	2666	0	29	21
A-D	-20.7865	-1.5674	-96.7137	-119.0676	59	11	0	4011	2	35	22
A-J	-33.0254	-3.1411	-179.133	-215.2995	95	16	3	8189	6	52	38
B-C	-18.0718	-1.6288	-93.0386	-112.7392	58	11	0	3994	2	35	22
C-D	-29.3224	-116.3701	-192.884	-338.5765	98	26	8	8763	9	17	15
E-F	-15.1241	-113.2398	-199.452	-327.8159	100	23	7	8767	9	21	16
E-H	-30.891	-20.4418	-80.4508	-131.7836	49	6	1	3041	3	23	16
E-I	-2.1103	-3.0404	-48.2857	-53.4364	59	3	0	2252	0	28	16
E-J	-32.3386	-32.8134	-113.859	-179.011	58	13	0	4383	2	38	23
F-G	-29.0592	-21.2934	-76.826	-127.1786	53	2	1	3057	4	23	17
F-H	0.0	5.2561	-31.9722	-26.716	18	0	0	1457	0	2	1
F-I	-27.2306	-1.63	-112.564	-141.4246	59	7	0	4228	2	37	22
F-L	0.0	0.0	-5.6837	-5.6837	13	1	0	351	0	4	9
G-H	-11.5192	-98.7305	-191.828	-302.0776	99	16	7	8524	8	17	16
G-K	0.0	-2.8123	-11.9468	-14.7591	54	11	0	1711	0	28	15
G-L	-19.027	-37.2813	-105.286	-161.5943	59	14	0	4302	2	38	23
H-J	0.0	0.0	-5.4117	-5.4117	13	0	0	379	0	4	9
H-K	-17.4731	-33.9503	-109.607	-161.0304	62	12	0	4282	2	37	23
I-J	-24.0873	-118.2961	-172.522	-314.9054	97	26	8	8778	10	19	18
I-L	-34.717	-20.9976	-77.8853	-133.5999	51	11	1	3233	4	23	18
J-K	-33.5858	-18.1256	-74.1831	-125.8946	51	7	1	3092	3	23	17
J-L	0.0	4.7782	-25.8854	-21.1072	17	0	0	1300	0	2	1
K-L	-24.5549	-84.173	-178.419	-287.1468	98	17	7	8463	8	18	16

Interface residues

• A-B: ALA831A, ALA831B, ALA835A, ALA835B, ALA838A, ALA838B, ALA841A, ALA841B, ALA855A, ALA855B, ALA856A, ALA856B, ALA858A, ALA858B, ALA889A, ALA889B, ALA892A, ALA892B, ARG847A, ARG847B, ARG883A, ARG883B, ASN837A, ASN837B, ASN845A, ASN845B, ASN852A, ASN852B, ASN860A, ASN860B, ASP846A, ASP846B, ASP894A, ASP894B, GLN840A, GLN840B, GLN930A, GLN930B, GLU851A, GLU851B, GLU888A, GLU888B, HIS853A, HIS853B, HIS854A, HIS854B, HIS876A, HIS876B, ILE887A, ILE887B, ILE890A, ILE890B, LEU833A, LEU833B, LEU843A, LEU843B, LEU850A, LEU850B, LEU861A, LEU861B, LEU863A, LEU863B, LEU891A, LEU891B, LEU926A, LEU926B, LEU971A, LYS880A, LYS880B, PHE832A, PHE832B, PHE879A, PHE879B, PHE884A, PHE884B, PHE901A, PHE901B, PRO839A, PRO839B, SER848A, SER848B, SER857A, SER857B, SER864A, SER864B, THR836A, THR836B, TRP859A, TRP859B, TYR844A, TYR844B, TYR862A, TYR862B, VAL834A, VAL834B, VAL842A, VAL842B, VAL849A, VAL886B
• A-C: ALA1005A, ALA1005C, ALA903A, ALA903C, ALA907C, ARG1054A, ARG1054C, ARG1055A, ARG1055C, ARG1056A, ARG1056C, ASN1001A, ASN1001C, ASN906A, ASN906C, ASN913A, ASN913C, ASN915A, ASN915C, ASP1004A, ASP1004C, ASP900A, ASP900C, ASP911A, ASP911C, CYS1059A, CYS1059C, GLU904C, GLU989A, GLU989C, HIS1063A, HIS1063C, HIS1069A, HIS1069C, HIS898A, HIS898C, HIS994A, HIS994C, ILE1057A, ILE1057C, ILE995A, ILE995C, LEU1014A, LEU1014C, LEU902A, LEU902C, LYS1073A, LYS1073C, MET1062A, MET1062C, PHE1058A, PHE1058C, PHE899A, PHE899C, PRO998A, PRO998C, SER1002A, SER1053A, SER1053C, SER914A, SER914C, SER990A, THR1066A, THR1066C, THR993A, THR993C, TRP1013A, TRP1013C, VAL912A, VAL912C
• A-D: ALA785D, ALA907D, ALA985A, ARG783D, ARG881D, ARG925D, ARG945A, ARG979A, ASN1068A, ASN780D, ASN913D, ASN915D, ASN921D, ASN923D, ASP875D, ASP924D, ASP946A, ASP978A, GLN983A, GLN988A, GLU1067A, GLU810D, GLU878D, GLU904D, GLU918D, GLU922D, GLU989A, GLY782D, GLY916D, HIS1063A, HIS1069A, HIS781D, HIS948A, ILE1071A, ILE784D, ILE917D, ILE973A, LEU809D, LEU927D, LEU949A, LEU984A, LEU987A, LYS1070A, LYS1073A, LYS880D, LYS908D, LYS986A, PHE976A, PRO807D, PRO982A, SER914D, SER920D, SER980A, SER981A, TRP1072A, TRP919D, TYR960A, VAL877D, VAL956A
• A-J: ALA1016J, ARG1054J, ARG1055J, ARG1056J, ARG694A, ARG725A, ARG945J, ASN1020J, ASN676J, ASN678J, ASN722A, ASN765A, ASN794A, ASP1019J, ASP1021J, ASP660A, ASP668A, ASP706A, ASP796A, ASP796J, ASP946J, CYS1059J, CYS792A, GLN1012J, GLN1060J, GLN698A, GLN705A, GLN718A, GLN719A, GLU1015J, GLU1017J, GLU1018J, GLU1023J, GLU1067J, GLU665A, GLU666A, GLU672A, GLU672J, GLU683J, GLU711A, GLU797A, GLU797J, GLY1011J, GLY708A, GLY766A, HIS1063J, HIS1064J, HIS873A, ILE1057J, ILE662A, ILE671A, ILE712A, ILE715A, ILE787A, LEU1014J, LEU661A, LEU663A, LEU709A, LEU710A, LEU872A, LEU947J, LYS1070J, LYS673J, LYS691A, LYS714A, LYS790A, MET721A, PHE1058J, PHE704A, PHE713A, PHE720A, PRO680J, PRO716A, PRO758J, PRO795A, PRO795J, SER1024J, SER669A, SER788A, SER789A, SER791A, SER793A, SER798A, SER798J, THR1022J, THR1066J, THR702A, THR707A, THR717A, TRP1013J, TYR667A, TYR701A, TYR799J, VAL664A, VAL944J
• B-C: ALA785B, ALA907B, ALA985C, ARG783B, ARG881B, ARG925B, ARG945C, ARG979C, ASN1068C, ASN780B, ASN913B, ASN915B, ASN921B, ASN923B, ASP875B, ASP924B, ASP978C, GLN983C, GLN988C, GLU1067C, GLU810B, GLU878B, GLU904B, GLU918B, GLU922B, GLU989C, GLY782B, GLY916B, HIS1063C, HIS1069C, HIS781B, HIS948C, ILE1071C, ILE784B, ILE917B, ILE973C, LEU809B, LEU927B, LEU949C, LEU984C, LEU987C, LYS1070C, LYS1073C, LYS908B, LYS986C, PHE976C, PRO807B, PRO982C, SER914B, SER920B, SER980C, SER981C, TRP1072C, TRP919B, TYR786B, TYR960C, VAL877B, VAL956C
• C-D: ALA831C, ALA831D, ALA835C, ALA835D, ALA838C, ALA838D, ALA841C, ALA841D, ALA855C, ALA855D, ALA856C, ALA856D, ALA858C, ALA858D, ALA889C, ALA889D, ALA892C, ALA892D, ARG847C, ARG847D, ARG883C, ARG883D, ASN837C, ASN837D, ASN845C, ASN845D, ASN852C, ASN852D, ASN860C, ASN860D, ASP846C, ASP846D, ASP894C, ASP894D, GLN840C, GLN840D, GLN930C, GLN930D, GLU851C, GLU851D, GLU888C, GLU888D, HIS853C, HIS853D, HIS854C, HIS854D, HIS876C, HIS876D, ILE887C, ILE887D, ILE890C, ILE890D, LEU833C, LEU833D, LEU843C, LEU843D, LEU850C, LEU850D, LEU861C, LEU861D, LEU863C, LEU863D, LEU891C, LEU891D, LEU926C, LEU926D, LYS880C, LYS880D, PHE832C, PHE832D, PHE879C, PHE879D, PHE884C, PHE884D, PHE901C, PHE901D, PRO839C, PRO839D, SER848C, SER848D, SER857C, SER857D, SER864C, SER864D, THR836C, THR836D, TRP859C, TRP859D, TYR844C, TYR844D, TYR862C, TYR862D, VAL834C, VAL834D, VAL842C, VAL842D, VAL849C, VAL886D
• E-F: ALA831E, ALA831F, ALA835E, ALA835F, ALA838E, ALA838F, ALA841E, ALA841F, ALA855E, ALA855F, ALA856E, ALA856F, ALA858E, ALA858F, ALA889E, ALA889F, ALA892E, ALA892F, ARG847E, ARG847F, ARG883E, ARG883F, ASN837E, ASN837F, ASN845E, ASN845F, ASN852E, ASN852F, ASN860E, ASN860F, ASP846E, ASP846F, ASP894E, ASP894F, GLN840E, GLN840F, GLN930E, GLN930F, GLU851E, GLU851F, GLU888E, GLU888F, HIS853E, HIS853F, HIS854E, HIS854F, HIS876E, HIS876F, ILE887E, ILE887F, ILE890E, ILE890F, LEU833E, LEU833F, LEU843E, LEU843F, LEU850E, LEU850F, LEU861E, LEU861F, LEU863E, LEU863F, LEU891E, LEU891F, LEU926E, LEU926F, LEU971E, LYS880E, LYS880F, PHE832E, PHE832F, PHE879E, PHE879F, PHE884E, PHE884F, PHE901E, PHE901F, PRO839E, PRO839F, SER848E, SER848F, SER857E, SER857F, SER864E, SER864F, THR836E, THR836F, TRP859E, TRP859F, TYR844E, TYR844F, TYR862E, TYR862F, VAL834E, VAL834F, VAL842E, VAL842F, VAL849E, VAL849F, VAL886F
• E-H: ALA838E, ALA967E, ARG739E, ARG778H, ARG828E, ARG979E, ASN729E, ASN780H, ASN837E, ASN869H, ASN968E, ASP776H, ASP875H, ASP964E, ASP978E, GLN718H, GLN719H, GLN962E, GLU656H, GLU711H, GLU867H, GLU961E, GLU965E, GLU966E, GLY777H, GLY963E, GLY970E, HIS781H, HIS873H, HIS876H, ILE779H, ILE973E, LEU872H, LEU874H, LEU969E, LEU971E, LYS714H, MET977E, PHE713H, PHE832E, PRO716H, PRO839E, PRO866H, PRO982E, SER980E, SER981E, THR836E, TYR960E, VAL842E
• E-I: ALA1005E, ALA1005I, ALA903E, ALA903I, ARG1054E, ARG1054I, ARG1055E, ARG1055I, ARG1056E, ARG1056I, ASN1001E, ASN1001I, ASN906E, ASN906I, ASN913E, ASN913I, ASN915E, ASN915I, ASP900E, ASP900I, ASP911E, ASP911I, CYS1059E, CYS1059I, GLU989E, GLU989I, HIS1063E, HIS1063I, HIS1069E, HIS1069I, HIS898E, HIS898I, HIS994E, HIS994I, ILE1057E, ILE1057I, ILE995E, ILE995I, LEU1014E, LEU1014I, LEU902E, LEU902I, LYS1073E, LYS1073I, PHE1058E, PHE1058I, PHE899E, PHE899I, PRO998E, PRO998I, SER1053E, SER1053I, SER914E, SER914I, THR1066E, THR993E, THR993I, VAL912E, VAL912I
• E-J: ALA785J, ALA907J, ALA985E, ARG783J, ARG881J, ARG925J, ARG945E, ARG979E, ASN1068E, ASN780J, ASN913J, ASN915J, ASN921J, ASN923J, ASP875J, ASP924J, ASP978E, GLN983E, GLN988E, GLU1067E, GLU810J, GLU878J, GLU904J, GLU918J, GLU922J, GLU989E, GLY782J, GLY916J, HIS1063E, HIS1069E, HIS781J, HIS948E, ILE1071E, ILE784J, ILE917J, ILE973E, LEU809J, LEU927J, LEU949E, LEU984E, LEU987E, LYS1070E, LYS1073E, LYS880J, LYS908J, LYS986E, PHE976E, PRO807J, PRO982E, SER914J, SER920J, SER980E, SER981E, TRP1072E, TRP919J, TYR960E, VAL877J, VAL956E
• F-G: ALA838G, ALA967G, ARG694G, ARG739G, ARG778F, ARG828G, ARG979G, ASN722F, ASN729G, ASN780F, ASN837G, ASN869F, ASN968G, ASP776F, ASP875F, ASP964G, ASP978G, GLN718F, GLN719F, GLN962G, GLU656F, GLU690G, GLU867F, GLU961G, GLU965G, GLU966G, GLY693G, GLY777F, GLY963G, GLY970G, HIS781F, HIS873F, HIS876F, ILE779F, ILE973G, LEU872F, LEU874F, LEU969G, LYS714F, MET977G, PHE713F, PHE832G, PHE959G, PRO716F, PRO839G, PRO866F, PRO982G, SER980G, SER981G, THR836G, TYR960G, VAL657F, VAL842G
• F-H: ARG865F, ARG865H, ASN860F, ASN860H, GLU867F, GLU867H, LEU861F, LEU861H, LEU863F, LEU863H, PRO866F, PRO866H, SER864F, SER864H, TYR862F, TYR862H, TYR868F, TYR868H
• F-I: ALA785F, ALA907F, ALA967I, ALA985I, ARG783F, ARG881F, ARG925F, ARG945I, ARG979I, ASN1068I, ASN780F, ASN913F, ASN915F, ASN921F, ASN923F, ASP875F, ASP924F, ASP978I, GLN983I, GLN988I, GLU1067I, GLU810F, GLU878F, GLU904F, GLU918F, GLU922F, GLU989I, GLY782F, GLY916F, HIS1063I, HIS1069I, HIS781F, HIS948I, ILE1071I, ILE784F, ILE917F, ILE973I, LEU809F, LEU927F, LEU949I, LEU984I, LEU987I, LYS1070I, LYS1073I, LYS908F, LYS986I, PHE976I, PRO807F, PRO982I, SER914F, SER920F, SER980I, SER981I, TRP1072I, TRP919F, TYR786F, TYR960I, VAL877F, VAL956I
• F-L: ARG778F, ARG778L, ARG783F, ARG783L, ASN780F, ASN780L, ASP776F, ASP776L, GLY782F, GLY782L, HIS781F, HIS781L, ILE779F
• G-H: ALA831G, ALA831H, ALA835G, ALA835H, ALA838G, ALA838H, ALA841G, ALA841H, ALA855G, ALA855H, ALA856G, ALA856H, ALA858G, ALA858H, ALA889G, ALA889H, ALA892G, ALA892H, ARG847G, ARG847H, ARG883G, ARG883H, ASN837G, ASN837H, ASN845G, ASN845H, ASN852G, ASN852H, ASN860G, ASN860H, ASP846G, ASP846H, ASP894G, ASP894H, GLN840G, GLN840H, GLN930G, GLN930H, GLU851G, GLU851H, GLU888G, GLU888H, HIS853G, HIS853H, HIS854G, HIS854H, HIS876G, HIS876H, ILE887G, ILE887H, ILE890G, ILE890H, LEU833G, LEU833H, LEU843G, LEU843H, LEU850G, LEU850H, LEU861G, LEU861H, LEU863G, LEU863H, LEU891G, LEU891H, LEU926G, LEU926H, LEU971G, LYS880G, LYS880H, PHE832G, PHE832H, PHE879G, PHE879H, PHE884G, PHE884H, PHE901G, PHE901H, PRO839G, PRO839H, SER848G, SER848H, SER857G, SER857H, SER864H, THR836G, THR836H, TRP859G, TRP859H, TYR844G, TYR844H, TYR862G, TYR862H, VAL834G, VAL834H, VAL842G, VAL842H, VAL849G, VAL849H, VAL886H
• G-K: ALA1005G, ALA1005K, ALA903G, ALA903K, ARG1054G, ARG1054K, ARG1055G, ARG1055K, ARG1056G, ARG1056K, ASN1001G, ASN1001K, ASN906G, ASN906K, ASN913G, ASN913K, ASP900G, ASP900K, ASP911G, ASP911K, CYS1059G, CYS1059K, GLU989G, GLU989K, HIS1069G, HIS1069K, HIS898G, HIS898K, HIS994G, HIS994K, ILE1057G, ILE1057K, ILE995G, ILE995K, LEU1014G, LEU1014K, LEU902G, LEU902K, LYS1073G, LYS1073K, PHE1058G, PHE1058K, PHE899G, PHE899K, PRO998G, PRO998K, SER1053G, SER1053K, SER914G, SER914K, THR993G, THR993K, VAL912G, VAL912K
• G-L: ALA785L, ALA907L, ALA985G, ARG783L, ARG881L, ARG925L, ARG945G, ARG979G, ASN1068G, ASN780L, ASN913L, ASN915L, ASN921L, ASN923L, ASP875L, ASP924L, ASP946G, ASP978G, GLN983G, GLN988G, GLU1067G, GLU810L, GLU878L, GLU904L, GLU918L, GLU922L, GLU989G, GLY782L, GLY916L, HIS1063G, HIS1069G, HIS781L, HIS948G, ILE1071G, ILE784L, ILE917L, ILE973G, LEU809L, LEU927L, LEU949G, LEU984G, LEU987G, LYS1070G, LYS1073G, LYS880L, LYS908L, LYS986G, PHE976G, PRO807L, PRO982G, SER914L, SER920L, SER980G, SER981G, TRP1072G, TRP919L, TYR960G, VAL877L, VAL956G
• H-J: ARG778H, ARG778J, ARG783H, ARG783J, ASN780H, ASN780J, ASP776H, ASP776J, GLY782H, GLY782J, HIS781H, HIS781J, ILE784J
• H-K: ALA785H, ALA907H, ALA967K, ALA985K, ARG783H, ARG881H, ARG925H, ARG945K, ARG979K, ASN1068K, ASN780H, ASN913H, ASN915H, ASN921H, ASN923H, ASP875H, ASP924H, ASP946K, ASP978K, GLN983K, GLN988K, GLU1067K, GLU810H, GLU878H, GLU904H, GLU918H, GLU922H, GLU989K, GLY782H, GLY916H, HIS1063K, HIS1069K, HIS781H, HIS948K, ILE1071K, ILE784H, ILE917H, ILE973K, LEU809H, LEU927H, LEU949K, LEU984K, LEU987K, LYS1070K, LYS1073K, LYS908H, LYS986K, PHE884H, PHE976K, PRO807H, PRO982K, SER914H, SER920H, SER980K, SER981K, THR952K, TRP1072K, TRP919H, TYR786H, TYR960K, VAL877H, VAL956K
• I-J: ALA831I, ALA831J, ALA835I, ALA835J, ALA838I, ALA838J, ALA841I, ALA841J, ALA855I, ALA855J, ALA856I, ALA856J, ALA858I, ALA858J, ALA889I, ALA889J, ALA892I, ALA892J, ARG847I, ARG847J, ARG883I, ARG883J, ASN837I, ASN837J, ASN845I, ASN845J, ASN852I, ASN852J, ASN860I, ASN860J, ASP846I, ASP846J, ASP894I, ASP894J, GLN840I, GLN840J, GLN930I, GLN930J, GLU851I, GLU851J, GLU888I, GLU888J, HIS853I, HIS853J, HIS854I, HIS854J, HIS876J, ILE887I, ILE887J, ILE890I, ILE890J, LEU833I, LEU833J, LEU843I, LEU843J, LEU850I, LEU850J, LEU861I, LEU861J, LEU863I, LEU863J, LEU891I, LEU891J, LEU926I, LEU926J, LYS880I, LYS880J, PHE832I, PHE832J, PHE879I, PHE879J, PHE884I, PHE884J, PHE901I, PHE901J, PRO839I, PRO839J, SER848I, SER848J, SER857I, SER857J, SER864I, SER864J, THR836I, THR836J, TRP859I, TRP859J, TYR844I, TYR844J, TYR862I, TYR862J, VAL834I, VAL834J, VAL842I, VAL842J, VAL849I, VAL886J
• I-L: ALA838I, ALA967I, ARG739I, ARG778L, ARG828I, ARG979I, ASN722L, ASN729I, ASN780L, ASN837I, ASN869L, ASN968I, ASP776L, ASP875L, ASP964I, ASP978I, GLN718L, GLN719L, GLN962I, GLU656L, GLU711L, GLU867L, GLU961I, GLU965I, GLU966I, GLY777L, GLY963I, GLY970I, HIS781L, HIS873L, HIS876L, ILE779L, ILE973I, LEU872L, LEU874L, LEU969I, LEU971I, LYS714L, MET977I, PHE713L, PHE832I, PRO716L, PRO839I, PRO866L, PRO982I, SER974I, SER980I, SER981I, THR836I, TYR960I, VAL842I
• J-K: ALA838K, ALA967K, ARG739K, ARG778J, ARG828K, ARG979K, ASN722J, ASN729K, ASN780J, ASN837K, ASN869J, ASN968K, ASP776J, ASP875J, ASP964K, ASP978K, GLN718J, GLN719J, GLN962K, GLU656J, GLU867J, GLU961K, GLU965K, GLU966K, GLY693K, GLY777J, GLY963K, GLY970K, HIS781J, HIS873J, HIS876J, ILE779J, ILE973K, LEU871J, LEU872J, LEU874J, LEU969K, LEU971K, LYS714J, MET977K, PHE713J, PHE832K, PRO716J, PRO839K, PRO866J, PRO982K, SER980K, SER981K, THR836K, TYR960K, VAL842K
• J-L: ARG865J, ARG865L, ASN860J, ASN860L, GLU867J, GLU867L, LEU861J, LEU861L, LEU863J, LEU863L, PRO866J, PRO866L, SER864J, SER864L, TYR862J, TYR868J, TYR868L
• K-L: ALA831K, ALA831L, ALA835K, ALA835L, ALA838K, ALA838L, ALA841K, ALA841L, ALA855K, ALA855L, ALA856K, ALA856L, ALA858K, ALA858L, ALA889K, ALA889L, ALA892K, ALA892L, ARG847K, ARG847L, ARG883K, ARG883L, ASN837K, ASN837L, ASN845K, ASN845L, ASN852K, ASN852L, ASN860K, ASN860L, ASP846K, ASP846L, ASP894K, ASP894L, GLN840K, GLN840L, GLN930K, GLN930L, GLU851K, GLU851L, GLU888K, GLU888L, HIS853K, HIS853L, HIS854K, HIS854L, HIS876K, HIS876L, ILE887K, ILE887L, ILE890K, ILE890L, LEU833K, LEU833L, LEU843K, LEU843L, LEU850K, LEU850L, LEU861K, LEU861L, LEU863K, LEU863L, LEU891K, LEU891L, LEU926K, LEU971K, LYS880K, LYS880L, PHE832K, PHE832L, PHE879K, PHE879L, PHE884K, PHE884L, PHE901K, PHE901L, PRO839K, PRO839L, SER848K, SER848L, SER857K, SER857L, SER864L, THR836K, THR836L, TRP859K, TRP859L, TYR844K, TYR844L, TYR862K, TYR862L, VAL834K, VAL834L, VAL842K, VAL842L, VAL849K, VAL849L, VAL886L