1SI8

crystal structure of e. faecalis catalase

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 311
  • Norm. En. per Res.: -5.2077
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-146.0283	-14.1585	-565.403	-725.5897	207	31	16	20990	2	56	69
A-C	-282.9336	-3.3942	-1049.37	-1335.6978	316	39	15	42274	2	94	109
A-D	-237.0686	-208.5527	-1116.6	-1562.2213	310	56	28	43517	24	146	149
B-C	-252.3196	-227.0515	-1140.22	-1619.5911	311	55	27	44012	24	151	148
B-D	-272.777	-9.2911	-1061.06	-1343.1281	316	31	15	42024	2	94	107
C-D	-137.873	-10.1923	-576.767	-724.8323	209	29	16	21070	2	56	69

Interface residues

• A-B: ALA160A, ALA160B, ALA23A, ALA23B, ALA347A, ALA347B, ALA396A, ALA396B, ALA41A, ALA41B, ARG149A, ARG149B, ARG152A, ARG152B, ARG342A, ARG342B, ARG371A, ARG371B, ARG454A, ARG454B, ARG45A, ARG45B, ASN150A, ASN150B, ASN363A, ASN363B, ASN369A, ASN369B, ASN374A, ASN374B, ASN376A, ASN376B, ASN380A, ASN380B, ASN384A, ASN384B, ASN406A, ASN406B, ASN409A, ASN409B, ASN448A, ASN448B, ASP142A, ASP142B, ASP163A, ASP163B, ASP339A, ASP339B, ASP33A, ASP33B, ASP367A, ASP367B, GLN147A, GLN147B, GLN32A, GLN32B, GLN331A, GLN365A, GLN365B, GLU159A, GLU159B, GLU170A, GLU170B, GLU378A, GLU378B, GLU382A, GLU382B, GLU392A, GLU392B, GLU402A, GLU402B, GLU404A, GLU404B, GLU450A, GLU450B, GLY24A, GLY24B, GLY27A, GLY27B, GLY346A, GLY346B, GLY368A, GLY368B, GLY375A, GLY375B, GLY405A, GLY405B, GLY408A, GLY408B, HIS145A, HIS145B, HIS154A, HIS154B, HIS167A, HIS167B, HIS343A, HIS343B, ILE134A, ILE134B, ILE138A, ILE138B, ILE144A, ILE144B, ILE31A, ILE31B, ILE379A, ILE379B, ILE398A, ILE398B, ILE451A, ILE451B, ILE452A, LEU21A, LEU21B, LEU30A, LEU30B, LEU36A, LEU36B, LEU37A, LEU37B, LEU40A, LEU40B, LYS139A, LYS139B, LYS148A, LYS148B, LYS200A, LYS200B, LYS366A, LYS366B, LYS397A, LYS397B, LYS447A, LYS447B, PHE143A, PHE143B, PHE164A, PHE164B, PHE335A, PHE335B, PHE401A, PHE401B, PRO141A, PRO141B, PRO151A, PRO151B, PRO169A, PRO169B, PRO28A, PRO28B, PRO326A, PRO326B, PRO383A, PRO383B, PRO394A, PRO394B, PRO49A, PRO49B, SER146A, SER146B, SER157A, SER157B, SER166A, SER166B, SER168A, SER168B, SER20A, SER20B, SER377A, SER377B, SER385A, SER385B, SER399A, SER399B, SER400A, SER400B, SER411A, THR153A, THR153B, THR22A, THR22B, TRP162A, TRP162B, TRP165A, TRP165B, TYR265A, TYR265B, TYR364A, TYR364B, TYR381A, TYR381B, TYR386A, TYR386B, TYR410A, TYR410B, VAL161A, VAL161B, VAL29A, VAL29B, VAL403A, VAL403B, VAL407A, VAL407B, VAL446A, VAL446B, VAL52A, VAL52B
• A-C: ALA137A, ALA137C, ALA23A, ALA23C, ALA306A, ALA306C, ALA324A, ALA324C, ALA336A, ALA336C, ALA340A, ALA340C, ALA347A, ALA347C, ALA357A, ALA357C, ALA359A, ALA359C, ALA396A, ALA396C, ALA41A, ALA41C, ARG333A, ARG333C, ARG342A, ARG342C, ARG344A, ARG344C, ARG371A, ARG371C, ARG45A, ARG45C, ARG47A, ARG47C, ASN121A, ASN121C, ASN17A, ASN17C, ASN19A, ASN19C, ASN303A, ASN303C, ASN317A, ASN317C, ASN348A, ASN348C, ASN355A, ASN355C, ASN362A, ASN362C, ASN363A, ASN363C, ASN369A, ASN369C, ASN373A, ASN373C, ASN374A, ASN374C, ASN376A, ASN376C, ASN380A, ASN380C, ASN384A, ASN384C, ASN44A, ASN44C, ASP118A, ASP118C, ASP123A, ASP123C, ASP16A, ASP16C, ASP327A, ASP327C, ASP339A, ASP339C, ASP33A, ASP33C, ASP367A, ASP367C, ASP393A, ASP393C, GLN10A, GLN10C, GLN18A, GLN18C, GLN310A, GLN310C, GLN32A, GLN32C, GLN331A, GLN331C, GLN351A, GLN351C, GLN356A, GLN356C, GLN365A, GLN365C, GLN4A, GLN4C, GLU119A, GLU119C, GLU249A, GLU249C, GLU25A, GLU25C, GLU302A, GLU302C, GLU307A, GLU307C, GLU309A, GLU309C, GLU323A, GLU323C, GLU378A, GLU378C, GLU382A, GLU382C, GLU388A, GLU388C, GLU38A, GLU38C, GLU392A, GLU392C, GLU402A, GLU402C, GLU404A, GLU404C, GLU46A, GLU46C, GLY11A, GLY11C, GLY120A, GLY120C, GLY15A, GLY15C, GLY24A, GLY24C, GLY27A, GLY27C, GLY316A, GLY316C, GLY321A, GLY321C, GLY332A, GLY332C, GLY338A, GLY338C, GLY346A, GLY346C, GLY368A, GLY368C, GLY375A, GLY375C, GLY408A, GLY408C, HIS245A, HIS245C, HIS341A, HIS341C, HIS343A, HIS343C, HIS350A, HIS350C, HIS35A, HIS35C, HIS42A, HIS42C, HIS5A, HIS5C, ILE31A, ILE31C, ILE322A, ILE322C, ILE354A, ILE354C, ILE398A, ILE398C, LEU21A, LEU21C, LEU30A, LEU30C, LEU330A, LEU330C, LEU334A, LEU334C, LEU352A, LEU352C, LEU36A, LEU36C, LEU37A, LEU37C, LEU40A, LEU40C, LEU6A, LEU6C, LYS114A, LYS114C, LYS200A, LYS200C, LYS328A, LYS328C, LYS358A, LYS358C, LYS366A, LYS366C, LYS391A, LYS391C, LYS397A, LYS397C, LYS39A, LYS39C, LYS75A, LYS75C, MET370A, MET370C, PHE115A, PHE115C, PHE305A, PHE305C, PHE313A, PHE313C, PHE318A, PHE318C, PHE335A, PHE335C, PHE372A, PHE372C, PHE401A, PHE401C, PHE43A, PHE43C, PRO13A, PRO13C, PRO28A, PRO28C, PRO301A, PRO301C, PRO315A, PRO315C, PRO320A, PRO320C, PRO326A, PRO326C, PRO353A, PRO353C, PRO360A, PRO360C, PRO383A, PRO383C, PRO390A, PRO390C, PRO394A, PRO394C, PRO49A, PRO49C, SER12A, SER12C, SER314A, SER314C, SER325A, SER325C, SER349A, SER349C, SER377A, SER377C, SER399A, SER399C, SER400A, SER400C, SER9A, SER9C, THR117A, THR117C, THR22A, THR22C, THR312A, THR312C, THR387A, THR387C, THR389A, THR389C, THR395A, THR395C, THR7A, THR7C, THR8A, THR8C, TYR116A, TYR116C, TYR122A, TYR122C, TYR304A, TYR304C, TYR364A, TYR364C, TYR381A, TYR381C, VAL14A, VAL14C, VAL311A, VAL311C, VAL319A, VAL319C, VAL345A, VAL345C, VAL34A, VAL34C, VAL361A, VAL361C, VAL403A, VAL403C, VAL407A, VAL407C, VAL48A, VAL48C
• A-D: ALA137A, ALA137D, ALA229A, ALA229D, ALA233A, ALA233D, ALA23A, ALA23D, ALA306A, ALA306D, ALA324A, ALA324D, ALA336A, ALA336D, ALA340A, ALA340D, ALA41A, ALA41D, ALA55A, ALA55D, ALA58A, ALA58D, ALA96A, ALA96D, ARG135A, ARG135D, ARG149A, ARG149D, ARG152A, ARG152D, ARG299A, ARG299D, ARG333A, ARG333D, ARG342A, ARG342D, ARG344A, ARG344D, ARG45A, ARG45D, ARG47A, ARG47D, ARG51A, ARG51D, ASN150A, ASN150D, ASN17A, ASN17D, ASN19A, ASN19D, ASN236A, ASN236D, ASN246A, ASN246D, ASN300A, ASN300D, ASN303A, ASN303D, ASN406A, ASN406D, ASN409A, ASN409D, ASN413A, ASN413D, ASN44A, ASN44D, ASP103A, ASP103D, ASP136A, ASP136D, ASP142A, ASP142D, ASP16A, ASP16D, ASP238A, ASP238D, ASP243A, ASP243D, ASP277A, ASP277D, ASP327A, ASP327D, ASP339A, ASP339D, ASP33A, ASP33D, GLN18A, GLN18D, GLN227A, GLN227D, GLN32A, GLN32D, GLN331A, GLN331D, GLU170A, GLU170D, GLU230A, GLU230D, GLU231A, GLU231D, GLU242A, GLU242D, GLU249A, GLU249D, GLU25A, GLU25D, GLU273A, GLU273D, GLU302A, GLU302D, GLU307A, GLU307D, GLU309A, GLU309D, GLU38A, GLU38D, GLU402A, GLU402D, GLU404A, GLU404D, GLU46A, GLU46D, GLU50A, GLU50D, GLU98A, GLU98D, GLY100A, GLY100D, GLY15A, GLY15D, GLY234A, GLY234D, GLY24A, GLY24D, GLY27A, GLY27D, GLY332A, GLY332D, GLY338A, GLY338D, GLY405A, GLY405D, GLY408A, GLY408D, GLY57A, GLY57D, GLY59A, GLY59D, GLY97A, GLY97D, HIS145A, HIS145D, HIS154A, HIS154D, HIS167A, HIS167D, HIS240A, HIS240D, HIS245A, HIS245D, HIS341A, HIS341D, HIS343A, HIS343D, HIS35A, HIS35D, HIS42A, HIS42D, HIS54A, HIS54D, HIS61A, HIS61D, ILE134A, ILE134D, ILE138A, ILE138D, ILE144A, ILE144D, ILE232A, ILE232D, ILE241A, ILE241D, ILE31A, ILE31D, ILE398A, ILE398D, LEU105A, LEU105D, LEU155A, LEU155D, LEU21A, LEU21D, LEU244A, LEU244D, LEU275A, LEU30A, LEU30D, LEU329A, LEU329D, LEU330A, LEU330D, LEU334A, LEU334D, LEU36A, LEU36D, LEU37A, LEU37D, LEU40A, LEU40D, LEU6A, LEU6D, LEU99A, LEU99D, LYS139A, LYS139D, LYS148A, LYS148D, LYS156A, LYS156D, LYS235A, LYS235D, LYS272A, LYS272D, LYS328A, LYS328D, LYS39A, LYS39D, LYS56A, LYS56D, MET271A, PHE140A, PHE140D, PHE143A, PHE143D, PHE164A, PHE164D, PHE239A, PHE239D, PHE26A, PHE26D, PHE276A, PHE276D, PHE305A, PHE305D, PHE335A, PHE335D, PHE401A, PHE401D, PHE43A, PHE43D, PRO141A, PRO141D, PRO151A, PRO151D, PRO237A, PRO237D, PRO28A, PRO28D, PRO301A, PRO301D, PRO326A, PRO326D, PRO49A, PRO49D, SER101A, SER101D, SER102A, SER102D, SER146D, SER168A, SER168D, SER20A, SER20D, SER325A, SER325D, SER411A, SER411D, THR104A, THR153A, THR153D, THR22A, THR22D, THR274A, THR274D, TYR304A, TYR304D, TYR337A, TYR337D, TYR410A, TYR410D, TYR412A, TYR412D, VAL14A, VAL14D, VAL29A, VAL29D, VAL308A, VAL308D, VAL403A, VAL403D, VAL407A, VAL407D, VAL48A, VAL48D, VAL52A, VAL52D, VAL53A, VAL53D, VAL95A, VAL95D
• B-C: ALA137B, ALA137C, ALA229B, ALA229C, ALA233B, ALA233C, ALA23B, ALA23C, ALA306B, ALA306C, ALA324B, ALA324C, ALA336B, ALA336C, ALA340B, ALA340C, ALA41B, ALA41C, ALA55B, ALA55C, ALA58B, ALA58C, ALA96B, ALA96C, ARG135B, ARG135C, ARG149B, ARG149C, ARG152B, ARG152C, ARG299B, ARG299C, ARG333B, ARG333C, ARG342B, ARG342C, ARG344B, ARG344C, ARG45B, ARG45C, ARG47B, ARG47C, ARG51B, ARG51C, ARG91B, ASN150B, ASN150C, ASN17B, ASN17C, ASN19B, ASN19C, ASN236B, ASN236C, ASN246B, ASN246C, ASN300B, ASN300C, ASN303B, ASN303C, ASN406B, ASN406C, ASN409B, ASN409C, ASN413B, ASN413C, ASN44B, ASN44C, ASP103B, ASP103C, ASP136B, ASP136C, ASP142B, ASP142C, ASP16B, ASP16C, ASP238B, ASP238C, ASP243B, ASP243C, ASP277B, ASP277C, ASP327B, ASP327C, ASP339B, ASP339C, ASP33B, ASP33C, GLN18B, GLN18C, GLN227B, GLN227C, GLN32B, GLN32C, GLN331B, GLN331C, GLU170B, GLU170C, GLU230B, GLU230C, GLU231B, GLU231C, GLU242B, GLU242C, GLU249B, GLU249C, GLU25B, GLU25C, GLU273B, GLU273C, GLU302B, GLU302C, GLU307B, GLU307C, GLU309B, GLU309C, GLU38B, GLU38C, GLU402B, GLU402C, GLU404B, GLU404C, GLU46B, GLU46C, GLU50B, GLU50C, GLU98B, GLU98C, GLY100B, GLY100C, GLY15B, GLY15C, GLY234B, GLY234C, GLY24B, GLY24C, GLY27B, GLY27C, GLY332B, GLY332C, GLY338B, GLY338C, GLY405B, GLY405C, GLY408B, GLY408C, GLY57B, GLY57C, GLY59B, GLY59C, GLY97B, GLY97C, HIS145B, HIS145C, HIS154B, HIS154C, HIS167B, HIS167C, HIS240B, HIS240C, HIS245B, HIS245C, HIS341B, HIS341C, HIS343B, HIS343C, HIS35B, HIS35C, HIS42B, HIS42C, HIS54B, HIS54C, HIS61B, HIS61C, ILE134B, ILE134C, ILE138B, ILE138C, ILE144B, ILE144C, ILE232B, ILE232C, ILE241B, ILE241C, ILE31B, ILE31C, ILE398B, ILE398C, LEU105B, LEU105C, LEU155B, LEU155C, LEU21B, LEU21C, LEU244B, LEU244C, LEU275C, LEU30B, LEU30C, LEU329B, LEU329C, LEU330B, LEU330C, LEU334B, LEU334C, LEU36B, LEU36C, LEU37B, LEU37C, LEU40B, LEU40C, LEU6B, LEU6C, LEU99B, LEU99C, LYS139B, LYS139C, LYS148B, LYS148C, LYS156B, LYS156C, LYS200C, LYS235B, LYS235C, LYS272B, LYS272C, LYS328B, LYS328C, LYS39B, LYS39C, LYS56B, LYS56C, MET271B, MET271C, PHE140B, PHE140C, PHE143B, PHE143C, PHE164B, PHE164C, PHE239B, PHE239C, PHE26B, PHE26C, PHE276B, PHE276C, PHE305B, PHE305C, PHE335B, PHE335C, PHE401B, PHE401C, PHE43B, PHE43C, PRO141B, PRO141C, PRO151B, PRO151C, PRO237B, PRO237C, PRO28B, PRO28C, PRO301B, PRO301C, PRO326B, PRO326C, PRO49B, PRO49C, SER101B, SER101C, SER102B, SER102C, SER168B, SER168C, SER20B, SER20C, SER325B, SER325C, SER411B, SER411C, THR153B, THR153C, THR22B, THR22C, THR274B, THR274C, TYR304B, TYR304C, TYR337B, TYR337C, TYR410B, TYR410C, TYR412B, TYR412C, VAL14B, VAL14C, VAL29B, VAL29C, VAL308B, VAL308C, VAL403B, VAL403C, VAL407B, VAL407C, VAL48B, VAL48C, VAL52B, VAL52C, VAL53B, VAL53C, VAL95B, VAL95C
• B-D: ALA137B, ALA137D, ALA23B, ALA23D, ALA306B, ALA306D, ALA324B, ALA324D, ALA336B, ALA336D, ALA340B, ALA340D, ALA347B, ALA347D, ALA357B, ALA357D, ALA359B, ALA359D, ALA396B, ALA396D, ALA41B, ALA41D, ARG333B, ARG333D, ARG342B, ARG342D, ARG344B, ARG344D, ARG371B, ARG371D, ARG45B, ARG45D, ARG47B, ARG47D, ASN121B, ASN121D, ASN17B, ASN17D, ASN19B, ASN19D, ASN303B, ASN303D, ASN317B, ASN317D, ASN348B, ASN348D, ASN355B, ASN355D, ASN362B, ASN362D, ASN363B, ASN363D, ASN369B, ASN369D, ASN373B, ASN373D, ASN374B, ASN374D, ASN376B, ASN376D, ASN380B, ASN380D, ASN384B, ASN384D, ASN406D, ASN44B, ASN44D, ASP118B, ASP118D, ASP123B, ASP123D, ASP16B, ASP16D, ASP327B, ASP327D, ASP339B, ASP339D, ASP33B, ASP33D, ASP367B, ASP367D, ASP393B, ASP393D, GLN10B, GLN10D, GLN18B, GLN18D, GLN310B, GLN310D, GLN32B, GLN32D, GLN331B, GLN331D, GLN351B, GLN351D, GLN356B, GLN356D, GLN365B, GLN365D, GLN4B, GLN4D, GLU119B, GLU119D, GLU249B, GLU249D, GLU25B, GLU25D, GLU302B, GLU302D, GLU307B, GLU307D, GLU309B, GLU309D, GLU323B, GLU323D, GLU378B, GLU378D, GLU382B, GLU382D, GLU388B, GLU388D, GLU38B, GLU38D, GLU392B, GLU392D, GLU402B, GLU402D, GLU404B, GLU404D, GLU46B, GLU46D, GLY11B, GLY11D, GLY120B, GLY120D, GLY15B, GLY15D, GLY24B, GLY24D, GLY27B, GLY27D, GLY316B, GLY316D, GLY321B, GLY321D, GLY332B, GLY332D, GLY338B, GLY338D, GLY346B, GLY346D, GLY368B, GLY368D, GLY375B, GLY375D, GLY408B, GLY408D, HIS245B, HIS245D, HIS341B, HIS341D, HIS343B, HIS343D, HIS350B, HIS350D, HIS35B, HIS35D, HIS42B, HIS42D, HIS5B, HIS5D, ILE31B, ILE31D, ILE354B, ILE354D, ILE398B, ILE398D, LEU21B, LEU21D, LEU30B, LEU30D, LEU330B, LEU330D, LEU334B, LEU334D, LEU352B, LEU352D, LEU36B, LEU36D, LEU37B, LEU37D, LEU40B, LEU40D, LEU6B, LEU6D, LYS114B, LYS114D, LYS200B, LYS200D, LYS328B, LYS328D, LYS358B, LYS358D, LYS366B, LYS366D, LYS391B, LYS391D, LYS397B, LYS397D, LYS39B, LYS39D, LYS75B, LYS75D, MET370B, MET370D, PHE115B, PHE115D, PHE305B, PHE305D, PHE313B, PHE313D, PHE318B, PHE318D, PHE335B, PHE335D, PHE372B, PHE372D, PHE401B, PHE401D, PHE43B, PHE43D, PRO13B, PRO13D, PRO28B, PRO28D, PRO301B, PRO301D, PRO315B, PRO315D, PRO320B, PRO320D, PRO326B, PRO326D, PRO353B, PRO353D, PRO360B, PRO360D, PRO383B, PRO383D, PRO390B, PRO390D, PRO394B, PRO394D, PRO49B, PRO49D, SER12B, SER12D, SER314B, SER314D, SER325B, SER325D, SER349B, SER349D, SER377B, SER377D, SER399B, SER399D, SER400B, SER400D, SER9B, SER9D, THR117B, THR117D, THR22B, THR22D, THR312B, THR312D, THR387B, THR387D, THR389B, THR389D, THR395B, THR395D, THR7B, THR7D, THR8B, THR8D, TYR116B, TYR116D, TYR122B, TYR122D, TYR304B, TYR304D, TYR337D, TYR364B, TYR364D, TYR381B, TYR381D, VAL14B, VAL14D, VAL311B, VAL311D, VAL319B, VAL319D, VAL345B, VAL345D, VAL34B, VAL34D, VAL361B, VAL361D, VAL403B, VAL403D, VAL407B, VAL407D, VAL48B, VAL48D
• C-D: ALA160C, ALA160D, ALA23C, ALA23D, ALA347C, ALA347D, ALA396C, ALA396D, ALA41C, ALA41D, ARG149C, ARG149D, ARG152C, ARG152D, ARG342C, ARG342D, ARG371C, ARG371D, ARG454C, ARG454D, ARG45C, ARG45D, ASN150C, ASN150D, ASN363C, ASN363D, ASN369C, ASN369D, ASN374C, ASN374D, ASN376C, ASN376D, ASN380C, ASN380D, ASN384C, ASN384D, ASN406C, ASN406D, ASN409C, ASN409D, ASN448C, ASN448D, ASP142C, ASP142D, ASP163C, ASP163D, ASP339C, ASP339D, ASP33C, ASP33D, ASP367C, ASP367D, GLN147C, GLN147D, GLN32C, GLN32D, GLN331C, GLN331D, GLN365C, GLN365D, GLU159C, GLU159D, GLU170C, GLU170D, GLU378C, GLU378D, GLU382C, GLU382D, GLU392C, GLU392D, GLU402C, GLU402D, GLU404C, GLU404D, GLU450C, GLU450D, GLY24C, GLY24D, GLY27C, GLY27D, GLY346C, GLY346D, GLY368C, GLY368D, GLY375C, GLY375D, GLY405C, GLY405D, GLY408C, GLY408D, HIS145C, HIS145D, HIS154C, HIS154D, HIS167C, HIS167D, HIS343C, HIS343D, ILE134C, ILE134D, ILE138C, ILE138D, ILE144C, ILE144D, ILE31C, ILE31D, ILE379C, ILE379D, ILE398C, ILE398D, ILE451C, ILE451D, LEU21C, LEU21D, LEU30C, LEU30D, LEU36C, LEU36D, LEU37C, LEU37D, LEU40C, LEU40D, LYS139C, LYS139D, LYS148C, LYS148D, LYS200C, LYS200D, LYS366C, LYS366D, LYS391C, LYS397C, LYS397D, LYS447C, LYS447D, PHE143C, PHE143D, PHE164C, PHE164D, PHE335C, PHE335D, PHE401C, PHE401D, PRO141C, PRO141D, PRO151C, PRO151D, PRO158C, PRO169C, PRO169D, PRO28C, PRO28D, PRO326C, PRO326D, PRO383C, PRO383D, PRO394C, PRO394D, PRO49C, PRO49D, SER146C, SER146D, SER157C, SER157D, SER166C, SER166D, SER168C, SER168D, SER20C, SER20D, SER377C, SER377D, SER385C, SER385D, SER399C, SER399D, SER400C, SER400D, SER411C, THR153C, THR153D, THR22C, THR22D, THR389D, TRP162C, TRP162D, TRP165C, TRP165D, TYR265C, TYR265D, TYR364C, TYR364D, TYR381C, TYR381D, TYR386C, TYR386D, TYR410C, TYR410D, VAL161C, VAL161D, VAL29C, VAL29D, VAL403C, VAL403D, VAL407C, VAL407D, VAL446C, VAL446D, VAL52D