1SFC

neuronal synaptic fusion complex

• Total interactions analyzed: 66
• Total true interactions: 33
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 133
  • Norm. En. per Res.: -4.6938
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-43.6956	-97.0524	-431.576	-572.324	135	26	23	18226	8	36	54
A-C	-11.9147	0.0	-32.9063	-44.821	61	5	0	2686	0	7	6
A-D	-89.8365	-123.1613	-411.277	-624.2748	133	39	23	18195	7	40	39
A-F	0.0	0.0	-0.0246	-0.0246	4	0	0	22	0	1	2
A-I	-38.374	-25.8809	-60.5481	-124.803	58	5	0	2439	7	35	12
A-J	-31.7236	-47.6726	-43.4598	-122.856	33	7	0	1867	3	13	12
B-C	-38.1994	-146.3035	-449.092	-633.5949	147	45	21	19630	10	57	77
B-D	-2.2229	-38.4592	-100.522	-141.204	81	4	4	5657	1	19	18
B-E	-10.1189	4.6195	-98.3251	-103.8245	40	2	1	3510	3	15	17
B-F	-12.4603	4.6322	-47.0811	-54.9092	42	7	0	2351	3	30	36
B-I	-30.1373	-49.3986	-45.3064	-124.8424	38	12	0	2115	3	13	10
B-J	0.0	-5.8815	-75.5598	-81.4413	38	7	0	2660	2	33	25
C-D	-85.5266	-135.5481	-392.876	-613.9507	135	34	10	15984	10	36	51
C-E	-17.0209	-34.2186	-33.2896	-84.5291	41	6	0	1768	3	20	21
C-F	0.0	0.0	-7.4963	-7.4963	12	0	0	399	0	9	7
E-F	-34.2641	-79.1259	-468.399	-581.7889	136	41	25	19103	5	35	58
E-G	0.0	0.0	-44.8774	-44.8774	55	1	1	2632	0	10	5
E-H	-60.4173	-106.0393	-412.533	-578.9896	125	66	22	17576	9	43	40
E-J	0.0	0.0	-0.0054	-0.0054	3	0	0	7	0	4	4
F-G	-30.5951	-107.7934	-440.867	-579.2555	143	40	19	18678	9	55	73
F-H	0.0	-41.155	-78.531	-119.686	83	19	2	5546	3	21	16
F-I	0.0	0.0	-0.1729	-0.1729	2	0	0	31	0	1	2
F-J	-7.6722	-20.408	-53.1924	-81.2725	46	1	0	2348	5	43	33
F-K	0.0	0.0	-7.8604	-7.8604	16	1	0	410	0	10	13
G-H	-59.7672	-108.4291	-394.832	-563.0283	137	41	11	16741	7	42	55
G-J	0.0	0.0	-4.5028	-4.5028	12	0	0	314	1	9	12
G-K	0.0	0.0	-0.3949	-0.3949	13	0	0	90	0	14	20
I-J	-38.5706	-74.7677	-441.77	-555.1083	132	41	25	18173	5	33	53
I-K	0.0	0.0	-46.2018	-46.2018	60	4	1	2567	0	8	6
I-L	-53.6691	-125.1362	-366.507	-545.3123	132	56	22	17560	7	38	38
J-K	-46.549	-136.9331	-435.458	-618.9401	147	43	21	19217	11	55	75
J-L	-6.434	-45.4018	-77.1684	-129.0043	83	10	3	5234	3	19	18
K-L	-57.1491	-138.8657	-370.231	-566.2458	136	50	12	16344	10	40	52

Interface residues

• A-B: ALA220B, ALA240B, ALA247B, ALA254B, ALA37A, ALA67A, ALA69A, ALA72A, ALA74A, ALA81A, ALA82A, ARG198B, ARG210B, ARG232B, ARG246B, ARG30A, ARG31A, ARG47A, ARG56A, ARG66A, ARG86A, ASN207B, ASN236B, ASN25A, ASN29A, ASN49A, ASN92A, ASP214B, ASP218B, ASP231B, ASP242B, ASP250B, ASP40A, ASP44A, ASP51A, ASP57A, ASP64A, ASP65A, ASP68A, GLN190B, GLN226B, GLN258B, GLN33A, GLN34A, GLN36A, GLN38A, GLN58A, GLN71A, GLN76A, GLU194B, GLU196B, GLU201B, GLU206B, GLU211B, GLU224B, GLU228B, GLU234B, GLU238B, GLU245B, GLU41A, GLU55A, GLU62A, GLU78A, GLY227B, GLY73A, HIS199B, HIS213B, HIS239B, ILE195B, ILE202B, ILE203B, ILE209B, ILE230B, ILE233B, ILE45A, LEU205B, LEU212B, LEU222B, LEU32A, LEU54A, LEU60A, LEU63A, LEU70A, LEU84A, LEU93A, LYS204B, LYS252B, LYS253B, LYS256B, LYS52A, LYS59A, LYS83A, LYS85A, LYS87A, LYS91A, MET215B, MET217B, MET219B, MET221B, MET229B, MET46A, PHE216B, PHE77A, SER200B, SER208B, SER225B, SER249B, SER259B, SER28A, SER61A, SER75A, SER80A, THR197B, THR251B, THR27A, THR35A, THR79A, TRP89A, TRP90A, TYR235B, TYR243B, TYR257B, TYR88A, VAL223B, VAL237B, VAL241B, VAL244B, VAL248B, VAL255B, VAL39A, VAL42A, VAL43A, VAL48A, VAL50A, VAL53A
• A-C: ALA42C, ALA67A, ALA74A, ALA74C, ALA81A, ARG56A, ARG66A, ASN49A, ASN68C, ASN77C, ASP51C, ASP70C, ASP80C, GLN53C, GLN56C, GLN71A, GLU52C, GLU61C, GLU73C, GLU75C, GLU78A, GLY43C, GLY54C, GLY63C, GLY73A, GLY82C, ILE67C, LEU32A, LEU47C, LEU50C, LEU57C, LEU60A, LEU63A, LEU70A, LEU78C, LEU81C, LEU84A, LYS76C, LYS83C, LYS85A, LYS87A, LYS91A, MET32C, MET46A, MET49C, MET64C, MET71C, PHE77A, SER25C, SER28C, SER39C, SER80A, THR29C, THR35A, THR46C, TYR88A, VAL36C, VAL39A, VAL42A, VAL53A, VAL60C
• A-D: ALA164D, ALA185D, ALA195D, ALA199D, ALA37A, ALA67A, ALA69A, ALA72A, ALA74A, ALA81A, ALA82A, ARG135D, ARG136D, ARG161D, ARG176D, ARG180D, ARG191D, ARG198D, ARG30A, ARG31A, ARG47A, ARG56A, ARG66A, ARG86A, ASN139D, ASN149D, ASN159D, ASN169D, ASN175D, ASN188D, ASN196D, ASN25A, ASN29A, ASN49A, ASP147D, ASP166D, ASP172D, ASP179D, ASP186D, ASP193D, ASP40A, ASP44A, ASP51A, ASP57A, ASP64A, ASP65A, ASP68A, GLN152D, GLN174D, GLN177D, GLN197D, GLN33A, GLN34A, GLN36A, GLN38A, GLN58A, GLN71A, GLN76A, GLU143D, GLU151D, GLU170D, GLU183D, GLU194D, GLU41A, GLU55A, GLU62A, GLU78A, GLY131D, GLY132D, GLY155D, GLY158D, GLY168D, GLY204D, GLY73A, HIS162D, ILE134D, ILE156D, ILE157D, ILE171D, ILE178D, ILE181D, ILE192D, ILE45A, LEU150D, LEU160D, LEU165D, LEU203D, LEU26A, LEU32A, LEU54A, LEU60A, LEU63A, LEU70A, LEU84A, LYS184D, LYS189D, LYS201D, LYS52A, LYS59A, LYS83A, LYS85A, LYS87A, LYS91A, MET146D, MET163D, MET167D, MET182D, MET202D, MET46A, PHE133D, PHE77A, SER154D, SER187D, SER28A, SER61A, SER75A, SER80A, THR138D, THR173D, THR190D, THR200D, THR27A, THR35A, THR79A, TYR88A, VAL137D, VAL153D, VAL39A, VAL42A, VAL43A, VAL48A, VAL50A, VAL53A
• A-F: GLU78A, LYS253F, LYS260F, LYS85A
• A-I: ALA69A, ALA69I, ALA72A, ALA72I, ALA74A, ALA74I, ALA82A, ALA82I, ARG56A, ARG56I, ARG66A, ARG66I, ARG86A, ARG86I, ASP57A, ASP57I, ASP64A, ASP64I, ASP65A, ASP65I, ASP68A, ASP68I, GLN58A, GLN58I, GLN71A, GLN71I, GLN76A, GLN76I, GLU62A, GLU62I, GLU78A, GLU78I, LEU54A, LEU54I, LEU60A, LEU60I, LYS59A, LYS59I, LYS83A, LYS83I, LYS85A, LYS85I, LYS94I, SER61A, SER61I, SER75A, SER75I, SER80A, SER80I, THR79A, THR79I, TRP89A, TRP89I, TRP90A, TRP90I, VAL50I, VAL53A, VAL53I
• A-J: ALA240J, ALA72A, ALA81A, ALA82A, ARG232J, ARG86A, ASN236J, ASN92A, ASP218J, ASP231J, ASP68A, GLN226J, GLN71A, GLN76A, GLU224J, GLU228J, GLU78A, HIS239J, LEU222J, LEU93A, LYS83A, LYS85A, MET221J, MET229J, PHE77A, SER225J, SER75A, SER80A, THR79A, TRP89A, TRP90A, TYR235J, TYR243J
• B-C: ALA18C, ALA191B, ALA220B, ALA22C, ALA240B, ALA247B, ALA254B, ALA42C, ALA74C, ARG16C, ARG17C, ARG198B, ARG210B, ARG232B, ARG246B, ARG30C, ARG31C, ARG45C, ARG59C, ASN207B, ASN236B, ASN65C, ASN68C, ASN77C, ASP19C, ASP214B, ASP218B, ASP231B, ASP23C, ASP242B, ASP250B, ASP41C, ASP51C, ASP58C, ASP70C, ASP80C, GLN15C, GLN190B, GLN20C, GLN226B, GLN258B, GLN34C, GLN53C, GLN56C, GLN69C, GLU10C, GLU12C, GLU13C, GLU194B, GLU196B, GLU201B, GLU206B, GLU211B, GLU224B, GLU228B, GLU234B, GLU238B, GLU245B, GLU24C, GLU27C, GLU37C, GLU38C, GLU52C, GLU55C, GLU61C, GLU62C, GLU73C, GLU75C, GLY227B, GLY43C, GLY54C, GLY63C, GLY82C, HIS199B, HIS213B, HIS239B, HIS66C, ILE195B, ILE202B, ILE203B, ILE209B, ILE230B, ILE233B, ILE44C, ILE67C, LEU11C, LEU192B, LEU205B, LEU212B, LEU21C, LEU222B, LEU26C, LEU33C, LEU35C, LEU47C, LEU50C, LEU57C, LEU78C, LEU81C, LYS189B, LYS204B, LYS252B, LYS253B, LYS256B, LYS40C, LYS72C, LYS76C, LYS79C, LYS83C, MET14C, MET215B, MET217B, MET219B, MET221B, MET229B, MET32C, MET49C, MET64C, MET71C, MET7C, PHE216B, SER188B, SER193B, SER200B, SER208B, SER225B, SER249B, SER259B, SER25C, SER28C, SER39C, THR197B, THR251B, THR29C, THR46C, TYR235B, TYR243B, TYR257B, VAL223B, VAL237B, VAL241B, VAL244B, VAL248B, VAL255B, VAL36C, VAL48C, VAL60C
• B-D: ALA164D, ALA185D, ALA191B, ALA195D, ALA199D, ALA220B, ALA240B, ALA247B, ALA254B, ARG135D, ARG136D, ARG142D, ARG161D, ARG191D, ARG198B, ASN139D, ASN144D, ASN149D, ASN159D, ASN175D, ASN188D, ASN196D, ASP140D, ASP147D, GLN174D, GLN190B, GLN226B, GLN258B, GLU143D, GLU194B, GLU196B, GLU201B, GLU206B, GLY168D, HIS162D, HIS199B, HIS213B, ILE134D, ILE156D, ILE157D, ILE171D, ILE178D, ILE181D, ILE192D, ILE195B, ILE202B, ILE209B, ILE230B, ILE233B, LEU150D, LEU160D, LEU165D, LEU192B, LEU205B, LEU212B, LYS189B, LYS189D, MET146D, MET163D, MET167D, MET182D, MET202D, MET215B, MET219B, MET229B, PHE133D, PHE216B, SER154D, SER193B, SER208B, THR138D, THR197B, THR251B, TYR243B, VAL137D, VAL153D, VAL223B, VAL237B, VAL241B, VAL244B, VAL255B
• B-E: ALA247B, ALA254B, ALA81E, ALA82E, ARG246B, ARG86E, ASN92E, ASP231B, ASP242B, ASP250B, GLN71E, GLU234B, GLU238B, GLU245B, GLU78E, HIS239B, LEU93E, LYS252B, LYS253B, LYS256B, LYS83E, LYS85E, LYS87E, LYS94E, MET95E, MET96E, SER249B, SER75E, THR251B, THR79E, TRP89E, TRP90E, TYR235B, TYR243B, TYR257B, VAL237B, VAL241B, VAL244B, VAL248B, VAL255B
• B-F: ALA247B, ALA247F, ALA261F, ARG232B, ARG232F, ARG246B, ARG246F, ASN236B, ASN236F, ASP231B, ASP242B, ASP242F, ASP250B, ASP250F, GLN226B, GLU224B, GLU228B, GLU234B, GLU238B, GLU245B, GLY227B, HIS239B, HIS239F, ILE230B, LYS252B, LYS253B, LYS253F, LYS260F, MET229B, SER225B, SER249B, SER249F, TYR235B, TYR235F, TYR243B, TYR243F, TYR257B, TYR257F, VAL237B, VAL241B, VAL244B, VAL248B
• B-I: ALA220B, ALA72I, ALA81I, ALA82I, ARG232B, ARG246B, ARG86I, ASN236B, ASN92I, ASP218B, ASP231B, ASP64I, ASP68I, GLN226B, GLN71I, GLN76I, GLU224B, GLU228B, GLU78I, GLY227B, HIS239B, ILE233B, LEU222B, LEU93I, LYS83I, LYS85I, MET221B, MET229B, PHE77I, SER225B, SER75I, SER80I, THR79I, TRP89I, TRP90I, TYR235B, TYR243B, VAL223B
• B-J: ALA240B, ALA240J, ALA247B, ALA247J, ARG232B, ARG232J, ARG246B, ARG246J, ASN236B, ASN236J, ASP231B, ASP231J, ASP242B, ASP242J, ASP250B, ASP250J, GLU228B, GLU228J, GLU234B, GLU234J, GLU238B, GLU238J, HIS239B, HIS239J, ILE233J, LYS253B, LYS253J, SER225B, SER225J, SER249B, SER249J, TYR235B, TYR235J, TYR243B, TYR243J, TYR257B, TYR257J, VAL237J
• C-D: ALA141D, ALA164D, ALA185D, ALA18C, ALA195D, ALA199D, ALA22C, ALA42C, ALA74C, ARG142D, ARG16C, ARG17C, ARG180D, ARG191D, ARG198D, ARG30C, ARG31C, ARG45C, ARG59C, ASN144D, ASN149D, ASN159D, ASN169D, ASN175D, ASN188D, ASN196D, ASN65C, ASN68C, ASN77C, ASP140D, ASP147D, ASP166D, ASP172D, ASP179D, ASP186D, ASP193D, ASP19C, ASP23C, ASP41C, ASP51C, ASP58C, ASP70C, ASP80C, GLN152D, GLN15C, GLN174D, GLN177D, GLN197D, GLN20C, GLN34C, GLN53C, GLN56C, GLN69C, GLU143D, GLU145D, GLU148D, GLU151D, GLU170D, GLU183D, GLU194D, GLU24C, GLU27C, GLU37C, GLU38C, GLU52C, GLU55C, GLU61C, GLU62C, GLU73C, GLU75C, GLY155D, GLY158D, GLY168D, GLY43C, GLY54C, GLY63C, GLY82C, HIS162D, HIS66C, ILE134D, ILE156D, ILE157D, ILE171D, ILE178D, ILE181D, ILE192D, ILE44C, ILE67C, LEU150D, LEU160D, LEU165D, LEU203D, LEU21C, LEU26C, LEU33C, LEU35C, LEU47C, LEU50C, LEU57C, LEU78C, LEU81C, LYS184D, LYS189D, LYS201D, LYS40C, LYS72C, LYS76C, LYS79C, LYS83C, MET146D, MET163D, MET167D, MET182D, MET202D, MET32C, MET49C, MET64C, MET71C, PHE133D, SER154D, SER187D, SER25C, SER28C, SER39C, THR138D, THR173D, THR190D, THR200D, THR29C, THR46C, VAL137D, VAL153D, VAL36C, VAL48C, VAL60C
• C-E: ALA72E, ALA74C, ALA74E, ALA82E, ARG45C, ARG59C, ARG86E, ASN65C, ASN68C, ASN77C, ASP64E, ASP68E, ASP70C, GLN56C, GLN69C, GLN71E, GLN76E, GLU52C, GLU55C, GLU62C, GLU73C, GLU78E, GLY63C, HIS66C, ILE67C, LEU93E, LYS72C, LYS76C, LYS83E, LYS85E, LYS94E, MET49C, MET71C, MET96E, PHE77E, SER75E, SER80E, THR79E, TRP89E, TRP90E, VAL48C
• C-F: ARG232F, ARG246F, ARG45C, ARG59C, ASN236F, GLN53C, GLN56C, GLU228F, GLU52C, HIS239F, TYR235F, TYR243F
• E-F: ALA220F, ALA240F, ALA247F, ALA254F, ALA261F, ALA37E, ALA67E, ALA69E, ALA72E, ALA74E, ALA81E, ALA82E, ARG198F, ARG210F, ARG232F, ARG246F, ARG31E, ARG47E, ARG56E, ARG66E, ARG86E, ASN207F, ASN236F, ASN29E, ASN49E, ASN92E, ASP214F, ASP218F, ASP231F, ASP242F, ASP250F, ASP40E, ASP44E, ASP51E, ASP57E, ASP64E, ASP65E, ASP68E, GLN226F, GLN258F, GLN33E, GLN34E, GLN36E, GLN38E, GLN58E, GLN71E, GLN76E, GLU194F, GLU196F, GLU201F, GLU206F, GLU211F, GLU224F, GLU228F, GLU234F, GLU238F, GLU245F, GLU41E, GLU55E, GLU62E, GLU78E, GLY227F, GLY73E, HIS199F, HIS213F, HIS239F, ILE195F, ILE202F, ILE203F, ILE209F, ILE230F, ILE233F, ILE45E, LEU205F, LEU212F, LEU222F, LEU32E, LEU54E, LEU60E, LEU63E, LEU70E, LEU84E, LEU93E, LYS204F, LYS252F, LYS253F, LYS256F, LYS260F, LYS52E, LYS59E, LYS83E, LYS85E, LYS87E, LYS91E, MET215F, MET217F, MET219F, MET221F, MET229F, MET46E, MET95E, MET96E, PHE216F, PHE77E, SER193F, SER200F, SER208F, SER225F, SER249F, SER259F, SER28E, SER61E, SER75E, SER80E, THR197F, THR251F, THR35E, THR79E, TRP89E, TRP90E, TYR235F, TYR243F, TYR257F, TYR88E, VAL223F, VAL237F, VAL241F, VAL244F, VAL248F, VAL255F, VAL39E, VAL42E, VAL43E, VAL48E, VAL50E, VAL53E
• E-G: ALA42G, ALA67E, ALA74E, ALA74G, ALA81E, ARG56E, ARG66E, ASN49E, ASN77G, ASP51G, ASP70G, ASP80G, GLN36E, GLN53G, GLN56G, GLN71E, GLU61G, GLU73G, GLU75G, GLY43G, GLY54G, GLY63G, GLY82G, ILE67G, LEU32E, LEU47G, LEU50G, LEU57G, LEU60E, LEU63E, LEU70E, LEU78G, LEU81G, LEU84E, LYS83G, LYS85E, LYS87E, MET32G, MET46E, MET49G, MET64G, MET71G, PHE77E, SER25G, SER39G, SER80E, THR29G, THR35E, THR46G, TYR88E, VAL36G, VAL39E, VAL42E, VAL53E, VAL60G
• E-H: ALA164H, ALA185H, ALA195H, ALA199H, ALA37E, ALA67E, ALA69E, ALA72E, ALA74E, ALA81E, ALA82E, ARG135H, ARG136H, ARG161H, ARG176H, ARG180H, ARG191H, ARG198H, ARG30E, ARG31E, ARG47E, ARG56E, ARG66E, ARG86E, ASN149H, ASN159H, ASN169H, ASN175H, ASN188H, ASN196H, ASN29E, ASN49E, ASP147H, ASP166H, ASP172H, ASP179H, ASP186H, ASP193H, ASP40E, ASP44E, ASP51E, ASP57E, ASP64E, ASP65E, ASP68E, GLN152H, GLN174H, GLN177H, GLN197H, GLN33E, GLN34E, GLN36E, GLN38E, GLN58E, GLN71E, GLN76E, GLU151H, GLU170H, GLU183H, GLU194H, GLU41E, GLU55E, GLU62E, GLU78E, GLY132H, GLY155H, GLY158H, GLY168H, GLY73E, HIS162H, ILE134H, ILE156H, ILE157H, ILE171H, ILE178H, ILE181H, ILE192H, ILE45E, LEU150H, LEU160H, LEU165H, LEU203H, LEU32E, LEU54E, LEU60E, LEU63E, LEU70E, LEU84E, LYS184H, LYS189H, LYS201H, LYS52E, LYS59E, LYS83E, LYS85E, LYS87E, LYS91E, MET146H, MET163H, MET167H, MET182H, MET202H, MET46E, PHE133H, PHE77E, SER154H, SER187H, SER28E, SER61E, SER75E, SER80E, THR173H, THR190H, THR200H, THR35E, THR79E, TYR88E, VAL137H, VAL153H, VAL39E, VAL42E, VAL43E, VAL48E, VAL50E, VAL53E
• E-J: HIS239J, LYS85E, TYR235J
• F-G: ALA18G, ALA191F, ALA220F, ALA22G, ALA240F, ALA247F, ALA254F, ALA42G, ALA74G, ARG16G, ARG17G, ARG198F, ARG210F, ARG232F, ARG246F, ARG30G, ARG31G, ARG45G, ARG59G, ASN207F, ASN236F, ASN65G, ASN68G, ASN77G, ASP19G, ASP214F, ASP218F, ASP231F, ASP23G, ASP242F, ASP250F, ASP41G, ASP51G, ASP58G, ASP70G, ASP80G, GLN15G, GLN190F, GLN20G, GLN226F, GLN258F, GLN34G, GLN53G, GLN56G, GLN69G, GLU12G, GLU13G, GLU194F, GLU196F, GLU201F, GLU206F, GLU211F, GLU224F, GLU228F, GLU234F, GLU238F, GLU245F, GLU24G, GLU27G, GLU37G, GLU38G, GLU52G, GLU55G, GLU61G, GLU62G, GLU73G, GLU75G, GLY227F, GLY43G, GLY54G, GLY63G, GLY82G, HIS199F, HIS213F, HIS239F, HIS66G, ILE195F, ILE202F, ILE203F, ILE209F, ILE230F, ILE233F, ILE44G, ILE67G, LEU192F, LEU205F, LEU212F, LEU21G, LEU222F, LEU26G, LEU33G, LEU35G, LEU47G, LEU50G, LEU57G, LEU78G, LEU81G, LYS189F, LYS204F, LYS252F, LYS253F, LYS256F, LYS40G, LYS72G, LYS76G, LYS79G, LYS83G, MET14G, MET215F, MET217F, MET219F, MET221F, MET229F, MET32G, MET49G, MET64G, MET71G, PHE216F, SER193F, SER200F, SER208F, SER225F, SER249F, SER259F, SER25G, SER28G, SER39G, THR197F, THR251F, THR29G, THR46G, TYR235F, TYR243F, TYR257F, VAL223F, VAL237F, VAL241F, VAL244F, VAL248F, VAL255F, VAL36G, VAL48G, VAL60G
• F-H: ALA164H, ALA185H, ALA191F, ALA195H, ALA199H, ALA220F, ALA240F, ALA247F, ALA254F, ARG135H, ARG136H, ARG142H, ARG161H, ARG198F, ASN139H, ASN144H, ASN149H, ASN159H, ASN188H, ASP140H, ASP147H, GLN174H, GLN190F, GLN226F, GLN258F, GLU143H, GLU170H, GLU194F, GLU196F, GLU201F, GLU206F, GLY132H, GLY158H, GLY168H, HIS162H, HIS199F, HIS213F, ILE134H, ILE156H, ILE157H, ILE171H, ILE178H, ILE181H, ILE192H, ILE195F, ILE202F, ILE203F, ILE209F, ILE230F, ILE233F, LEU150H, LEU160H, LEU165H, LEU192F, LEU205F, LEU212F, LEU222F, LYS189F, LYS189H, MET146H, MET163H, MET167H, MET182H, MET202H, MET215F, MET219F, MET229F, PHE216F, SER154H, SER193F, SER200F, SER208F, THR138H, THR197F, THR251F, TYR243F, VAL137H, VAL153H, VAL223F, VAL237F, VAL241F, VAL244F, VAL255F
• F-I: LYS85I, TYR235F
• F-J: ALA254F, ARG232F, ARG232J, ARG246F, ARG246J, ASN236J, ASP231F, ASP231J, ASP242F, ASP242J, ASP250F, ASP250J, GLU224J, GLU228F, GLU228J, GLU234F, GLU234J, GLU238F, GLU238J, GLU245F, GLU245J, GLY227F, GLY227J, HIS239F, HIS239J, ILE230F, ILE230J, LYS252F, LYS252J, LYS253F, LYS253J, LYS256F, LYS256J, LYS260F, SER225J, SER249F, SER249J, SER259F, TYR235F, TYR235J, TYR243F, TYR257F, VAL241F, VAL241J, VAL248F, VAL248J
• F-K: ARG45K, ARG59K, ASP70K, GLN53K, GLN56K, GLU238F, GLU245F, GLU52K, GLU55K, HIS66K, LYS252F, LYS256F, LYS260F, SER259F, VAL241F, VAL248F
• G-H: ALA141H, ALA164H, ALA185H, ALA18G, ALA195H, ALA199H, ALA22G, ALA42G, ALA74G, ARG142H, ARG161H, ARG16G, ARG176H, ARG17G, ARG180H, ARG191H, ARG198H, ARG30G, ARG31G, ARG45G, ARG59G, ASN144H, ASN149H, ASN159H, ASN169H, ASN175H, ASN188H, ASN196H, ASN65G, ASN68G, ASN77G, ASP140H, ASP147H, ASP166H, ASP172H, ASP179H, ASP186H, ASP193H, ASP19G, ASP23G, ASP41G, ASP51G, ASP58G, ASP70G, ASP80G, GLN152H, GLN15G, GLN174H, GLN177H, GLN197H, GLN20G, GLN34G, GLN53G, GLN56G, GLN69G, GLU143H, GLU145H, GLU148H, GLU151H, GLU170H, GLU183H, GLU194H, GLU24G, GLU27G, GLU37G, GLU38G, GLU52G, GLU55G, GLU61G, GLU62G, GLU73G, GLU75G, GLY132H, GLY155H, GLY158H, GLY168H, GLY43G, GLY54G, GLY63G, GLY82G, HIS162H, HIS66G, ILE134H, ILE156H, ILE157H, ILE171H, ILE178H, ILE181H, ILE192H, ILE44G, ILE67G, LEU150H, LEU160H, LEU165H, LEU203H, LEU21G, LEU26G, LEU33G, LEU35G, LEU47G, LEU50G, LEU57G, LEU78G, LEU81G, LYS184H, LYS189H, LYS201H, LYS40G, LYS72G, LYS76G, LYS79G, LYS83G, MET146H, MET163H, MET167H, MET182H, MET202H, MET32G, MET49G, MET64G, MET71G, SER154H, SER187H, SER25G, SER28G, SER39G, THR138H, THR173H, THR190H, THR200H, THR29G, THR46G, VAL137H, VAL153H, VAL36G, VAL48G, VAL60G
• G-J: ARG59G, GLN53G, GLN56G, GLU245J, GLU52G, GLU55G, HIS66G, LYS252J, LYS256J, SER249J, VAL241J, VAL248J
• G-K: ARG59G, ARG59K, ASN77G, GLN69G, GLN69K, GLU52K, GLU55G, GLU62G, GLU62K, GLU73G, GLU73K, HIS66G, HIS66K
• I-J: ALA220J, ALA240J, ALA247J, ALA254J, ALA37I, ALA67I, ALA69I, ALA72I, ALA74I, ALA81I, ALA82I, ARG198J, ARG210J, ARG232J, ARG246J, ARG30I, ARG31I, ARG47I, ARG56I, ARG66I, ARG86I, ASN207J, ASN236J, ASN29I, ASN49I, ASN92I, ASP214J, ASP218J, ASP231J, ASP242J, ASP250J, ASP40I, ASP44I, ASP51I, ASP57I, ASP64I, ASP65I, ASP68I, GLN226J, GLN258J, GLN33I, GLN34I, GLN36I, GLN38I, GLN58I, GLN71I, GLN76I, GLU194J, GLU201J, GLU206J, GLU211J, GLU224J, GLU228J, GLU234J, GLU238J, GLU245J, GLU41I, GLU55I, GLU62I, GLU78I, GLY227J, GLY73I, HIS199J, HIS213J, HIS239J, ILE195J, ILE202J, ILE203J, ILE209J, ILE230J, ILE233J, ILE45I, LEU205J, LEU212J, LEU222J, LEU32I, LEU54I, LEU60I, LEU63I, LEU70I, LEU84I, LEU93I, LYS204J, LYS252J, LYS253J, LYS256J, LYS52I, LYS59I, LYS83I, LYS85I, LYS87I, LYS91I, MET215J, MET217J, MET219J, MET221J, MET229J, MET46I, PHE216J, PHE77I, SER200J, SER208J, SER225J, SER249J, SER259J, SER28I, SER61I, SER75I, SER80I, THR197J, THR251J, THR27I, THR35I, THR79I, TRP89I, TRP90I, TYR235J, TYR243J, TYR257J, TYR88I, VAL223J, VAL237J, VAL241J, VAL244J, VAL248J, VAL255J, VAL39I, VAL42I, VAL43I, VAL48I, VAL50I, VAL53I
• I-K: ALA42K, ALA67I, ALA74I, ALA74K, ALA81I, ARG56I, ARG66I, ASN49I, ASN68K, ASN77K, ASP51K, ASP70K, ASP80K, GLN36I, GLN53K, GLN56K, GLN71I, GLU52K, GLU61K, GLU73K, GLU75K, GLY43K, GLY54K, GLY63K, GLY82K, ILE67K, LEU32I, LEU35K, LEU47K, LEU50K, LEU57K, LEU60I, LEU63I, LEU70I, LEU78K, LEU81K, LEU84I, LYS72K, LYS83K, LYS85I, LYS87I, LYS91I, MET32K, MET46I, MET49K, MET64K, MET71K, PHE77I, SER25K, SER39K, SER80I, THR29K, THR35I, THR46K, TYR88I, VAL36K, VAL39I, VAL42I, VAL53I, VAL60K
• I-L: ALA164L, ALA185L, ALA195L, ALA199L, ALA37I, ALA67I, ALA69I, ALA72I, ALA74I, ALA81I, ALA82I, ARG135L, ARG136L, ARG161L, ARG176L, ARG180L, ARG191L, ARG198L, ARG30I, ARG31I, ARG47I, ARG56I, ARG66I, ARG86I, ASN139L, ASN149L, ASN159L, ASN169L, ASN175L, ASN188L, ASN196L, ASN29I, ASN49I, ASP147L, ASP166L, ASP172L, ASP179L, ASP186L, ASP193L, ASP40I, ASP44I, ASP51I, ASP57I, ASP64I, ASP65I, ASP68I, GLN152L, GLN174L, GLN177L, GLN197L, GLN33I, GLN34I, GLN36I, GLN38I, GLN58I, GLN71I, GLN76I, GLU143L, GLU148L, GLU151L, GLU170L, GLU183L, GLU194L, GLU41I, GLU55I, GLU62I, GLU78I, GLY132L, GLY155L, GLY158L, GLY168L, GLY204L, GLY73I, HIS162L, ILE134L, ILE156L, ILE157L, ILE171L, ILE178L, ILE181L, ILE192L, ILE45I, LEU150L, LEU160L, LEU165L, LEU203L, LEU26I, LEU32I, LEU54I, LEU60I, LEU63I, LEU70I, LEU84I, LYS184L, LYS189L, LYS201L, LYS52I, LYS59I, LYS83I, LYS85I, LYS87I, LYS91I, MET146L, MET163L, MET167L, MET182L, MET202L, MET46I, PHE133L, PHE77I, SER154L, SER187L, SER28I, SER61I, SER75I, SER80I, THR138L, THR173L, THR190L, THR200L, THR27I, THR35I, THR79I, TYR88I, VAL137L, VAL153L, VAL39I, VAL42I, VAL43I, VAL48I, VAL50I, VAL53I
• J-K: ALA18K, ALA191J, ALA220J, ALA22K, ALA240J, ALA247J, ALA254J, ALA42K, ALA74K, ARG16K, ARG17K, ARG198J, ARG210J, ARG232J, ARG246J, ARG30K, ARG31K, ARG45K, ARG59K, ASN207J, ASN236J, ASN65K, ASN68K, ASN77K, ASP19K, ASP214J, ASP218J, ASP231J, ASP23K, ASP242J, ASP250J, ASP41K, ASP51K, ASP58K, ASP70K, ASP80K, GLN15K, GLN190J, GLN20K, GLN226J, GLN258J, GLN34K, GLN53K, GLN56K, GLN69K, GLU12K, GLU13K, GLU194J, GLU196J, GLU201J, GLU206J, GLU211J, GLU224J, GLU228J, GLU234J, GLU238J, GLU245J, GLU24K, GLU27K, GLU37K, GLU38K, GLU52K, GLU55K, GLU61K, GLU62K, GLU73K, GLU75K, GLY227J, GLY43K, GLY54K, GLY63K, GLY82K, HIS199J, HIS213J, HIS239J, HIS66K, ILE187J, ILE195J, ILE202J, ILE203J, ILE209J, ILE230J, ILE233J, ILE44K, ILE67K, LEU11K, LEU192J, LEU205J, LEU212J, LEU21K, LEU222J, LEU26K, LEU33K, LEU35K, LEU47K, LEU50K, LEU57K, LEU78K, LEU81K, LYS189J, LYS204J, LYS252J, LYS253J, LYS256J, LYS40K, LYS72K, LYS76K, LYS79K, LYS83K, MET14K, MET215J, MET217J, MET219J, MET221J, MET229J, MET32K, MET49K, MET64K, MET71K, PHE216J, SER186J, SER188J, SER193J, SER200J, SER208J, SER225J, SER249J, SER259J, SER25K, SER28K, SER39K, THR197J, THR251J, THR29K, THR46K, TYR235J, TYR243J, TYR257J, VAL223J, VAL237J, VAL241J, VAL244J, VAL248J, VAL255J, VAL36K, VAL48K, VAL60K
• J-L: ALA164L, ALA185L, ALA191J, ALA195L, ALA199L, ALA220J, ALA240J, ALA247J, ALA254J, ARG135L, ARG136L, ARG142L, ARG161L, ARG198J, ASN139L, ASN144L, ASN149L, ASN159L, ASN188L, ASN196L, ASP140L, ASP147L, GLN174L, GLN190J, GLN226J, GLN258J, GLU143L, GLU170L, GLU194J, GLU196J, GLU201J, GLU206J, GLY132L, GLY168L, HIS162L, HIS199J, HIS213J, ILE134L, ILE156L, ILE157L, ILE171L, ILE178L, ILE181L, ILE187J, ILE192L, ILE195J, ILE202J, ILE209J, ILE230J, ILE233J, LEU150L, LEU160L, LEU165L, LEU192J, LEU205J, LEU212J, LEU222J, MET146L, MET163L, MET167L, MET182L, MET202L, MET215J, MET217J, MET219J, MET229J, PHE133L, PHE216J, SER154L, SER188J, SER193J, SER208J, THR138L, THR197J, THR251J, TYR243J, VAL137L, VAL153L, VAL223J, VAL237J, VAL241J, VAL244J, VAL255J
• K-L: ALA141L, ALA164L, ALA185L, ALA18K, ALA195L, ALA199L, ALA22K, ALA42K, ALA74K, ARG142L, ARG161L, ARG16K, ARG176L, ARG17K, ARG180L, ARG191L, ARG198L, ARG30K, ARG31K, ARG45K, ARG59K, ASN144L, ASN149L, ASN159L, ASN169L, ASN175L, ASN188L, ASN196L, ASN65K, ASN68K, ASN77K, ASP140L, ASP147L, ASP166L, ASP172L, ASP179L, ASP186L, ASP193L, ASP19K, ASP23K, ASP41K, ASP51K, ASP58K, ASP70K, ASP80K, GLN152L, GLN15K, GLN174L, GLN177L, GLN197L, GLN20K, GLN34K, GLN53K, GLN56K, GLN69K, GLU143L, GLU145L, GLU148L, GLU151L, GLU170L, GLU183L, GLU194L, GLU24K, GLU27K, GLU37K, GLU38K, GLU52K, GLU55K, GLU61K, GLU62K, GLU73K, GLU75K, GLY155L, GLY158L, GLY168L, GLY43K, GLY54K, GLY63K, GLY82K, HIS162L, HIS66K, ILE134L, ILE156L, ILE157L, ILE171L, ILE178L, ILE181L, ILE192L, ILE44K, ILE67K, LEU150L, LEU160L, LEU165L, LEU203L, LEU21K, LEU26K, LEU33K, LEU35K, LEU47K, LEU50K, LEU57K, LEU78K, LEU81K, LYS184L, LYS189L, LYS201L, LYS40K, LYS72K, LYS76K, LYS79K, LYS83K, MET146L, MET163L, MET167L, MET182L, MET202L, MET32K, MET49K, MET64K, MET71K, SER154L, SER187L, SER25K, SER28K, SER39K, THR138L, THR173L, THR190L, THR200L, THR29K, THR46K, VAL137L, VAL153L, VAL36K, VAL48K, VAL60K