1S3S

crystal structure of aaa atpase p97/vcp nd1 in complex with p47 c

• Total interactions analyzed: 36
• Total true interactions: 9
• Strongest Interaction:
  • Chains: F-G
  • Int. Res.: 91
  • Norm. En. per Res.: -2.6988
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.008	-0.008	4	0	0	7	0	1	4
A-E	-43.4089	-83.2522	-284.007	-410.668	178	27	12	14636	12	97	68
A-F	-27.0482	-50.6584	-335.603	-413.3096	175	20	12	15561	9	107	74
B-D	-56.0193	-100.4281	-280.84	-437.2875	168	15	11	13077	16	93	67
B-F	-8.5065	-98.4299	-344.212	-451.1485	174	17	11	15685	12	112	78
B-H	-42.0108	-8.4585	-160.173	-210.6422	88	12	6	7715	1	15	13
C-D	-14.112	-22.4703	-286.169	-322.7513	161	17	13	13942	11	101	71
C-E	-56.6624	-99.2273	-297.535	-453.4248	170	39	10	14761	12	102	70
F-G	-32.8353	-19.9783	-192.773	-245.5866	91	16	6	8715	0	18	15

Interface residues

• A-B: GLU319A, GLY318A, HIS317A, HIS317B
• A-E: ALA160A, ALA214E, ALA228E, ALA232E, ALA279A, ALA279E, ALA308A, ALA310A, ALA346A, ALA356E, ALA409A, ALA412A, ALA413A, ALA418A, ALA419A, ALA422A, ALA439A, ALA455A, ARG159A, ARG225E, ARG256A, ARG25E, ARG287E, ARG313E, ARG322A, ARG322E, ARG323A, ARG323E, ARG338E, ARG349A, ARG358E, ARG359E, ARG362E, ARG365E, ARG424A, ASN199A, ASN270A, ASN348A, ASN387A, ASP304A, ASP307A, ASP333E, ASP354E, ASP364E, ASP410A, ASP428A, ASP431A, ASP434A, ASP438A, ASP98E, CYS415A, GLN215E, GLN327E, GLN421A, GLN458A, GLU124A, GLU218E, GLU221E, GLU273A, GLU281A, GLU281E, GLU283A, GLU283E, GLU305A, GLU319A, GLU319E, GLU321A, GLU366E, GLU417A, GLU433A, GLU435A, GLU80E, GLY125A, GLY156A, GLY157A, GLY234E, GLY248A, GLY250A, GLY271A, GLY280A, GLY280E, GLY318A, GLY318E, GLY334E, GLY361E, GLY408A, GLY97E, HIS226E, HIS317E, HIS384A, HIS406A, ILE100E, ILE126A, ILE216E, ILE233E, ILE274A, ILE27E, ILE309A, ILE324A, ILE324E, ILE423A, ILE430A, ILE437A, LEU222E, LEU229E, LEU253A, LEU268A, LEU26E, LEU278A, LEU286E, LEU306A, LEU328E, LEU329E, LEU331E, LEU411A, LEU414A, LEU420A, LEU429A, LEU432A, LEU445A, LEU96E, LYS211E, LYS217E, LYS231E, LYS236E, LYS251A, LYS277A, LYS312E, LYS315A, LYS425A, LYS62E, LYS81E, MET158A, MET219E, MET275A, MET388A, MET427A, MET442A, PHE230E, PHE302A, PHE360E, PRO223E, PRO227E, PRO237E, PRO238E, PRO246A, PRO247A, PRO272A, PRO311A, PRO355E, SER276A, SER282A, SER284E, SER326E, SER416A, SER457A, SER78E, THR127A, THR249A, THR252A, THR316A, THR316E, THR330E, THR436A, TRP454A, VAL123A, VAL220E, VAL235E, VAL28E, VAL320A, VAL320E, VAL325A, VAL325E, VAL367E, VAL407A, VAL441A, VAL447A, VAL99E
• A-F: ALA160F, ALA214A, ALA228A, ALA232A, ALA279A, ALA279F, ALA308F, ALA310F, ALA346F, ALA356A, ALA409F, ALA412F, ALA413F, ALA418F, ALA419F, ALA422F, ALA439F, ALA455F, ARG159F, ARG225A, ARG25A, ARG287A, ARG313A, ARG322A, ARG322F, ARG323A, ARG323F, ARG338A, ARG349F, ARG358A, ARG359A, ARG362A, ARG365A, ARG424F, ASN270F, ASN348F, ASN387F, ASN443F, ASP121F, ASP304F, ASP307F, ASP333A, ASP354A, ASP364A, ASP410F, ASP428F, ASP431F, ASP434F, ASP438F, ASP98A, CYS415F, GLN215A, GLN327A, GLN337A, GLN421F, GLN458F, GLU124F, GLU218A, GLU221A, GLU273F, GLU281F, GLU283A, GLU305F, GLU314A, GLU319A, GLU319F, GLU321F, GLU366A, GLU417F, GLU433F, GLU435F, GLU80A, GLY125F, GLY156F, GLY157F, GLY234A, GLY245F, GLY248F, GLY271F, GLY280A, GLY280F, GLY318A, GLY318F, GLY334A, GLY361A, GLY405F, GLY97A, HIS226A, HIS317A, HIS317F, HIS384F, HIS406F, ILE126F, ILE233A, ILE274F, ILE27A, ILE309F, ILE324A, ILE324F, ILE353F, ILE423F, ILE430F, ILE437F, LEU222A, LEU229A, LEU26A, LEU278F, LEU306F, LEU328A, LEU329A, LEU331A, LEU411F, LEU414F, LEU420F, LEU429F, LEU432F, LEU445F, LYS211A, LYS217A, LYS231A, LYS236A, LYS251F, LYS277F, LYS312A, LYS312F, LYS315A, LYS315F, LYS425F, LYS45A, LYS81A, MET158F, MET219A, MET275F, MET388F, MET427F, MET442F, PHE230A, PHE302F, PHE360A, PRO223A, PRO227A, PRO237A, PRO238A, PRO246F, PRO247F, PRO272F, PRO311F, PRO355A, SER276F, SER282F, SER326A, SER352F, SER416F, SER457F, THR127F, THR249F, THR252F, THR316A, THR316F, THR330A, THR347F, THR436F, TRP454F, TYR134F, VAL123F, VAL220A, VAL235A, VAL320A, VAL320F, VAL325A, VAL367A, VAL407F, VAL441F, VAL447F, VAL99A
• B-D: ALA160D, ALA214B, ALA228B, ALA232B, ALA279B, ALA279D, ALA308D, ALA346D, ALA356B, ALA409D, ALA412D, ALA413D, ALA418D, ALA419D, ALA422D, ALA439D, ALA455D, ARG159D, ARG225B, ARG25B, ARG287B, ARG313B, ARG322B, ARG322D, ARG323B, ARG323D, ARG338B, ARG358B, ARG359B, ARG362B, ARG365B, ARG424D, ASN199D, ASN270D, ASN348D, ASN387D, ASN443D, ASP121D, ASP304D, ASP307D, ASP333B, ASP364B, ASP410D, ASP428D, ASP431D, ASP434D, ASP438D, ASP98B, CYS415D, GLN215B, GLN327B, GLN337B, GLN421D, GLN458D, GLU124D, GLU218B, GLU221B, GLU273D, GLU281D, GLU283B, GLU305D, GLU314B, GLU319B, GLU319D, GLU321B, GLU321D, GLU366B, GLU417D, GLU435D, GLU80B, GLY125D, GLY156D, GLY157D, GLY234B, GLY248D, GLY250D, GLY271D, GLY280B, GLY280D, GLY318B, GLY318D, GLY361B, GLY408D, GLY97B, HIS226B, HIS317B, HIS317D, HIS384D, ILE126D, ILE216B, ILE233B, ILE274D, ILE27B, ILE309D, ILE324B, ILE324D, ILE423D, ILE430D, ILE437D, LEU222B, LEU229B, LEU253D, LEU268D, LEU278D, LEU306D, LEU328B, LEU329B, LEU331B, LEU357B, LEU411D, LEU414D, LEU420D, LEU429D, LEU432D, LEU445D, LYS211B, LYS217B, LYS231B, LYS236B, LYS251D, LYS277D, LYS315B, LYS315D, LYS425D, LYS81B, MET158D, MET219B, MET275D, MET388D, MET427D, MET442D, PHE230B, PHE302D, PHE360B, PRO223B, PRO227B, PRO237B, PRO238B, PRO247D, PRO272D, PRO311D, PRO355B, SER276D, SER282D, SER326B, SER416D, SER457D, SER78B, THR127D, THR249D, THR252D, THR316B, THR316D, THR330B, THR347D, THR436D, TRP454D, TYR134D, VAL123D, VAL220B, VAL235B, VAL320B, VAL320D, VAL325B, VAL367B, VAL407D, VAL441D, VAL99B
• B-F: ALA160B, ALA214F, ALA228F, ALA232F, ALA279B, ALA279F, ALA308B, ALA346B, ALA356F, ALA409B, ALA412B, ALA413B, ALA418B, ALA419B, ALA422B, ALA439B, ALA455B, ARG159B, ARG225F, ARG22F, ARG25F, ARG287F, ARG313F, ARG322B, ARG322F, ARG323B, ARG323F, ARG338F, ARG358F, ARG359F, ARG362F, ARG365F, ARG424B, ASN21F, ASN270B, ASN348B, ASN351B, ASN387B, ASP304B, ASP307B, ASP333F, ASP364F, ASP410B, ASP428B, ASP431B, ASP434B, ASP438B, ASP98F, CYS415B, GLN19F, GLN215F, GLN327F, GLN337F, GLN421B, GLN458B, GLU124B, GLU218F, GLU221F, GLU273B, GLU281B, GLU283F, GLU305B, GLU314F, GLU319B, GLU319F, GLU321B, GLU321F, GLU366F, GLU417B, GLU433B, GLU435B, GLU80F, GLY125B, GLY157B, GLY234F, GLY248B, GLY250B, GLY271B, GLY280B, GLY280F, GLY318B, GLY318F, GLY334F, GLY361F, GLY408B, GLY97F, HIS226F, HIS317B, HIS317F, HIS384B, HIS406B, ILE100F, ILE126B, ILE233F, ILE274B, ILE27F, ILE309B, ILE324B, ILE324F, ILE423B, ILE430B, ILE437B, LEU222F, LEU229F, LEU253B, LEU268B, LEU26F, LEU278B, LEU286F, LEU328F, LEU329F, LEU331F, LEU411B, LEU414B, LEU420B, LEU429B, LEU432B, LEU445B, LYS20F, LYS217F, LYS231F, LYS236F, LYS251B, LYS277B, LYS315B, LYS425B, LYS62F, LYS81F, MET158B, MET219F, MET275B, MET388B, MET427B, MET442B, PHE230F, PHE302B, PHE360F, PRO223F, PRO227F, PRO237F, PRO238F, PRO246B, PRO247B, PRO272B, PRO311B, PRO355F, SER276B, SER282B, SER326F, SER352B, SER416B, SER457B, THR122B, THR127B, THR249B, THR252B, THR316B, THR316F, THR330F, THR385B, THR436B, TRP454B, TYR134B, VAL123B, VAL220F, VAL235F, VAL320B, VAL320F, VAL325B, VAL325F, VAL407B, VAL441B, VAL447B, VAL99F
• B-H: ALA142B, ALA177B, ALA264H, ALA303H, ALA363H, ARG113B, ARG144B, ARG301H, ARG307H, ARG368H, ARG53B, ASN297H, ASN33B, ASN345H, ASN359H, ASN362H, ASN36B, ASP107B, ASP179B, ASP304H, ASP35B, ASP47B, ASP55B, CYS105B, CYS174B, CYS69B, GLN258H, GLN299H, GLN310H, GLN367H, GLN43B, GLN50B, GLU141B, GLU347H, GLY257H, GLY261H, GLY305H, GLY306H, GLY54B, ILE175B, ILE298H, ILE300H, ILE365H, ILE70B, LEU140B, LEU302H, LEU308H, LEU360H, LEU361H, LEU369H, LEU51B, LEU72B, LYS109B, LYS259H, LYS311H, MET340H, MET46B, PHE139B, PHE343H, PHE52B, PRO104B, PRO106B, PRO145B, PRO170B, PRO178B, PRO265H, PRO344H, SER262H, SER37B, SER73B, THR263H, THR296H, THR341H, THR342H, THR370H, THR56B, TYR110B, TYR138B, TYR143B, VAL108B, VAL181B, VAL309H, VAL364H, VAL366H, VAL38B, VAL39B, VAL57B, VAL71B
• C-D: ALA160C, ALA214D, ALA228D, ALA232D, ALA279C, ALA279D, ALA308C, ALA346C, ALA356D, ALA409C, ALA412C, ALA413C, ALA418C, ALA419C, ALA422C, ALA439C, ALA455C, ARG159C, ARG225D, ARG287D, ARG313D, ARG322D, ARG323D, ARG338D, ARG358D, ARG359D, ARG362D, ARG365D, ARG424C, ASN270C, ASN348C, ASN387C, ASP304C, ASP307C, ASP333D, ASP364D, ASP410C, ASP428C, ASP434C, ASP438C, ASP98D, CYS415C, GLN215D, GLN327D, GLN337D, GLN421C, GLN458C, GLU124C, GLU218D, GLU221D, GLU273C, GLU281C, GLU283D, GLU305C, GLU314D, GLU319C, GLU319D, GLU321C, GLU321D, GLU366D, GLU417C, GLU433C, GLU435C, GLU80D, GLY125C, GLY156C, GLY157C, GLY234D, GLY248C, GLY250C, GLY271C, GLY280D, GLY318C, GLY318D, GLY361D, GLY408C, GLY97D, HIS226D, HIS317C, HIS317D, HIS384C, HIS406C, ILE126C, ILE233D, ILE274C, ILE27D, ILE309C, ILE324C, ILE324D, ILE423C, ILE430C, ILE437C, LEU222D, LEU229D, LEU253C, LEU268C, LEU278C, LEU328D, LEU329D, LEU331D, LEU411C, LEU414C, LEU420C, LEU429C, LEU432C, LEU445C, LYS217D, LYS231D, LYS236D, LYS251C, LYS277C, LYS315C, LYS315D, LYS425C, LYS62D, LYS81D, MET158C, MET219D, MET275C, MET388C, MET427C, MET442C, PHE230D, PHE302C, PHE360D, PRO223D, PRO227D, PRO237D, PRO238D, PRO246C, PRO247C, PRO272C, PRO311C, PRO355D, SER276C, SER282C, SER326D, SER416C, SER457C, THR122C, THR127C, THR249C, THR252C, THR316C, THR316D, THR330D, THR385C, THR436C, TRP454C, TYR134C, VAL123C, VAL220D, VAL235D, VAL320C, VAL320D, VAL325D, VAL367D, VAL407C, VAL441C, VAL447C, VAL99D
• C-E: ALA160E, ALA214C, ALA228C, ALA232C, ALA279C, ALA279E, ALA308E, ALA346E, ALA356C, ALA409E, ALA412E, ALA413E, ALA418E, ALA419E, ALA422E, ALA439E, ARG159E, ARG225C, ARG256E, ARG25C, ARG287C, ARG313C, ARG322C, ARG322E, ARG323C, ARG338C, ARG358C, ARG359C, ARG362C, ARG365C, ARG424E, ASN270E, ASN348E, ASN387E, ASP304E, ASP307E, ASP333C, ASP354C, ASP364C, ASP410E, ASP428E, ASP431E, ASP434E, ASP438E, ASP98C, CYS415E, GLN215C, GLN327C, GLN337C, GLN421E, GLN458E, GLU124E, GLU218C, GLU221C, GLU273E, GLU281E, GLU283C, GLU283E, GLU305E, GLU314C, GLU319C, GLU319E, GLU321C, GLU321E, GLU366C, GLU417E, GLU433E, GLU435E, GLU80C, GLY125E, GLY156E, GLY157E, GLY234C, GLY248E, GLY250E, GLY271E, GLY280C, GLY280E, GLY318C, GLY318E, GLY334C, GLY361C, GLY408E, GLY97C, HIS226C, HIS317C, HIS317E, HIS384E, HIS406E, ILE126E, ILE216C, ILE233C, ILE274E, ILE27C, ILE303E, ILE309E, ILE324C, ILE324E, ILE423E, ILE430E, ILE437E, LEU222C, LEU229C, LEU253E, LEU268E, LEU278E, LEU306E, LEU328C, LEU329C, LEU331C, LEU411E, LEU414E, LEU420E, LEU429E, LEU432E, LEU445E, LYS217C, LYS231C, LYS236C, LYS251E, LYS277E, LYS315C, LYS315E, LYS425E, LYS426E, LYS62C, LYS81C, MET158E, MET219C, MET275E, MET388E, MET427E, MET442E, PHE230C, PHE302E, PHE360C, PRO223C, PRO227C, PRO237C, PRO238C, PRO246E, PRO247E, PRO272E, PRO311E, PRO355C, SER276E, SER282E, SER326C, SER416E, SER457E, SER78C, THR127E, THR249E, THR252E, THR316C, THR316E, THR330C, THR385E, THR436E, TRP454E, TYR134E, VAL123E, VAL220C, VAL235C, VAL320C, VAL320E, VAL325C, VAL407E, VAL441E, VAL99C
• F-G: ALA142F, ALA177F, ALA264G, ALA303G, ALA363G, ARG113F, ARG144F, ARG301G, ARG307G, ARG368G, ARG53F, ASN297G, ASN33F, ASN345G, ASN359G, ASN362G, ASN36F, ASP107F, ASP179F, ASP304G, ASP35F, ASP47F, ASP55F, CYS105F, CYS174F, CYS69F, GLN258G, GLN266G, GLN299G, GLN310G, GLN367G, GLN43F, GLN50F, GLU141F, GLU256G, GLU347G, GLY111F, GLY257G, GLY261G, GLY305G, GLY306G, GLY54F, HIS183F, ILE175F, ILE298G, ILE300G, ILE365G, ILE70F, LEU140F, LEU302G, LEU308G, LEU360G, LEU361G, LEU369G, LEU51F, LEU72F, LYS109F, LYS136F, LYS259G, LYS311G, LYS356G, MET340G, MET46F, PHE139F, PHE343G, PHE52F, PRO106F, PRO145F, PRO170F, PRO178F, PRO265G, PRO344G, SER262G, SER37F, SER73F, THR180F, THR263G, THR296G, THR341G, THR342G, THR56F, TYR110F, TYR138F, TYR143F, TYR173F, VAL108F, VAL181F, VAL364G, VAL366G, VAL38F, VAL71F