1S1I

structure of the ribosomal 80s-eef2-sordarin complex from yeast obtained by docking atomic models for rna and protein components into a 11.7 a cryo-em map. this file, 1s1i, contains 60s subunit. the 40s ribosomal subunit is in file 1s1h.

• Total interactions analyzed: 435
• Total true interactions: 18
• Strongest Interaction:
  • Chains: D-O
  • Int. Res.: 20
  • Norm. En. per Res.: -0.8985
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-J	0.0	0.0	-0.0008	-0.0008	2	0	0	2	0	1	1
A-Z	0.0	-6.6309	-8.9003	-15.5311	26	1	0	853	0	8	18
B-9	-161.0868	-183.1135	2242.26	1898.0597	113	398	17	14959	1	13	30
C-M	0.0	3.6958	204.279	207.9748	15	24	0	1263	0	0	7
C-R	-77.7845	-1150.4992	2068.34	840.0564	61	249	1	7815	4	29	42
C-S	-29.5378	-8.5172	2062.93	2024.875	56	290	2	6741	0	8	10
D-O	-3.1645	3.1007	-17.9054	-17.9692	20	7	1	1364	0	4	5
D-Y	0.0	52.6718	76.8953	129.5671	10	37	0	602	0	1	3
E-J	0.0	1.1424	-0.821	0.3214	9	0	0	119	0	4	5
E-Q	-6.8713	3.9941	1145.27	1142.3928	38	151	2	3011	0	3	18
G-L	0.0	-14.8399	434.543	419.7031	53	81	4	5384	0	22	10
H-M	-46.5894	16.8226	4639.33	4609.5632	51	673	7	13039	0	13	41
L-Z	-5.4175	1.4801	312.508	308.5706	16	63	0	1221	0	0	2
N-Y	0.0	0.0	-1.1344	-1.1344	8	0	0	157	0	0	3
O-V	0.0	1.1852	-14.814	-13.6288	23	0	0	1350	0	17	19
P-W	0.0	0.0	-0.0289	-0.0289	2	0	0	19	0	0	0
R-S	-3.0079	20.4497	1460.61	1478.0518	58	258	7	7670	0	11	11
T-X	0.0	0.0	-2.4148	-2.4148	35	7	1	1263	0	8	4

Interface residues

• A-J: ASN141A, LYS63J
• A-Z: ALA29Z, ARG45A, ARG70Z, ASN197A, ASN2Z, ASP46A, GLN26Z, GLU72Z, GLU91Z, HIS89Z, LEU193A, LEU194A, LYS195A, LYS196A, LYS23Z, LYS28Z, LYS47A, LYS5Z, LYS77Z, PHE90Z, SER192A, THR25Z, TYR27Z, VAL191A, VAL24Z, VAL74Z
• B-9: ALA169B, ALA181B, ALA509, ALA519, ALA55B, ALA58B, ALA649, ALA679, ALA739, ALA749, ALA759, ALA769, ALA77B, ARG169, ARG173B, ARG183B, ARG229, ARG239, ARG489, ARG53B, ARG799, ASN131B, ASN78B, ASN96B, ASP175B, ASP379, ASP50B, CYS389, CYS569, CYS599, GLN249, GLN329, GLN46B, GLN85B, GLU299, GLU79B, GLY109B, GLY130B, GLY166B, GLY170B, GLY171B, GLY172B, GLY182B, GLY189, GLY499, GLY529, GLY54B, GLY659, GLY669, GLY80B, GLY84B, GLY98B, HIS186B, HIS49B, HIS82B, ILE111B, ILE134B, ILE165B, ILE168B, ILE47B, ILE539, ILE76B, LEU178B, LEU179B, LEU219, LEU289, LEU57B, LEU95B, LYS176B, LYS180B, LYS269, LYS279, LYS45B, LYS59B, LYS609, LYS619, PHE409, PRO107B, PRO177B, PRO56B, SER113B, SER129B, SER199, SER209, SER399, SER51B, SER719, SER809, THR110B, THR559, THR629, THR699, THR729, THR779, THR83B, TRP549, TYR132B, TYR139, TYR179, TYR689, VAL112B, VAL164B, VAL167B, VAL174B, VAL259, VAL44B, VAL469, VAL48B, VAL639, VAL709, VAL789, VAL81B, VAL97B
• C-M: ARG67M, ASN64M, HIS255C, HIS258C, LEU13C, LEU16C, LYS65M, MET260C, PRO256C, SER262C, THR66M, TRP254C, TRP261C, VAL259C, VAL263C
• C-R: ALA361C, ALA74C, ARG12R, ARG246C, ARG45R, ARG48R, ARG57C, ARG69C, ARG86R, ARG87R, ARG88R, ARG9C, ASN47R, ASP124R, ASP359C, ASP58C, ASP89R, GLU121R, GLU70C, GLU73C, GLY11C, GLY233C, GLY325C, GLY8R, GLY90R, HIS10C, HIS12C, HIS230C, HIS67C, ILE55C, LEU237C, LEU46R, LEU59C, LYS10R, LYS120R, LYS235C, LYS236C, LYS324C, LYS356C, LYS65C, LYS68C, PHE11R, PHE66C, PHE92R, PRO62C, PRO8C, SER44R, SER64C, THR229C, THR234C, THR53C, THR54C, THR9R, TRP232C, TRP357C, TRP85R, TYR282C, VAL56C, VAL71C, VAL72C, VAL91R
• C-S: ALA11S, ALA361C, ALA37S, ALA74C, ARG17S, ARG30S, ARG69C, ASN33S, ASP359C, GLN32S, GLU4S, GLU73C, GLY16S, GLY18S, GLY308C, GLY309C, GLY365C, GLY51C, ILE13S, ILE304C, ILE358C, ILE55C, ILE5S, LEU20S, LEU355C, LEU39S, LYS12S, LYS302C, LYS356C, LYS35S, LYS363C, MET307C, MET52C, PHE310C, PHE31S, PHE364C, PRO15S, PRO306C, SER296C, SER34S, SER362C, SER36S, SER38S, THR19S, THR303C, THR305C, THR360C, THR53C, THR54C, TRP357C, TYR14S, VAL311C, VAL56C, VAL71C, VAL72C, VAL75C
• D-O: ALA127D, ARG105O, ARG30D, ASN23O, ASP22O, ASP32D, HIS35D, ILE29D, ILE33D, LEU133D, LEU243D, LEU26O, LYS27O, LYS56O, PRO28D, PRO31D, THR107O, TYR119D, TYR25O, VAL24O
• D-Y: ALA50Y, ALA55D, GLN58D, GLU53D, GLY49Y, HIS57D, LYS51Y, LYS54D, THR59D, TRP48Y
• E-J: ARG140J, ARG142J, ARG152E, ASN57E, CYS143J, GLU25E, GLY26E, LEU150E, LYS141J
• E-Q: ALA24Q, ARG15E, ARG17Q, ARG20Q, ARG21E, ARG22E, ARG23E, ARG33E, ARG35E, ASP18Q, GLN17E, GLN32E, GLY23Q, HIS22Q, HIS26Q, HIS40E, LEU27Q, LEU31Q, LEU36E, LYS21Q, LYS34E, LYS48E, PHE16E, PHE19Q, PRO19E, PRO47E, SER13E, SER14E, SER28Q, THR18E, THR29Q, THR38E, TYR12E, TYR30E, TYR30Q, TYR31E, VAL25Q, VAL37E
• G-L: ALA140G, ALA167G, ALA197G, ALA2L, ALA38L, ALA39L, ARG25L, ARG40L, ARG43L, ARG48L, ARG62L, ASN136G, ASP157G, ASP16L, ASP45L, GLN10L, GLN22L, GLU160G, GLU7L, GLU8L, GLY134G, HIS137G, ILE142G, ILE159G, LEU135G, LEU161G, LEU165G, LEU168G, LEU18L, LEU21L, LEU6L, LEU9L, LYS13L, LYS4L, PHE164G, PHE20L, PRO158G, PRO166G, PRO41L, PRO44L, THR42L, TYR29L, TYR3L, TYR5L, VAL120L, VAL138G, VAL139G, VAL156G, VAL162G, VAL163G, VAL17L, VAL196G, VAL24L
• H-M: ALA122M, ALA56H, ALA66H, ALA67H, ARG124M, ARG127M, ARG132M, ARG23H, ARG62H, ARG69H, ASN59H, ASP42H, GLN8H, GLU39M, GLU7H, GLY12M, GLY131M, GLY60H, GLY61H, HIS40H, HIS58H, HIS64H, ILE41H, ILE53H, LEU123M, LEU126M, LEU128M, LEU38H, LEU68H, LYS11M, LYS129M, LYS133M, LYS39H, LYS47H, LYS54H, LYS63H, LYS72H, PHE45H, PRO130M, THR135M, THR44H, THR46H, THR70H, TYR134M, VAL125M, VAL43H, VAL55H, VAL57H, VAL65H, VAL71H, VAL75H
• L-Z: GLN46Z, GLN86L, GLU90L, GLY48Z, GLY50Z, GLY51Z, GLY81L, LYS45Z, LYS54Z, LYS82L, PHE49Z, PRO55Z, PRO83L, SER47Z, THR53Z, THR84L
• N-Y: ARG130N, GLY133N, GLY3Y, HIS132N, LYS2Y, PRO5Y, THR4Y, TYR129N
• O-V: ALA112O, ALA117O, ALA91O, ARG116V, ARG69O, ARG86V, ARG92O, ASN119V, ASP75V, ASP84V, ASP89O, ASP90O, GLU83V, ILE93O, LEU80V, LYS113O, LYS116O, LYS76V, LYS85V, SER65O, THR79V, TRP78V, VAL64O
• P-W: PRO25P, PRO52W
• R-S: ALA37S, ALA82R, ALA99R, ARG17S, ARG23S, ARG30S, ARG80R, ARG86R, ARG87R, ARG88R, ASN24R, ASN33S, ASN98R, ASP25S, ASP89R, ASP97R, GLN32S, GLN81R, GLU4S, GLU96R, GLY116R, GLY119R, GLY134R, GLY16S, GLY18S, GLY24S, GLY90R, ILE13R, ILE13S, ILE28S, LEU20S, LEU54R, LEU93R, LYS27S, LYS83R, PHE21S, PHE29S, PHE31S, PHE40S, PHE92R, PHE95R, PRO117R, PRO15S, SER26S, SER34S, SER84R, THR115R, THR19S, TRP85R, TYR14S, TYR94R, VAL118R, VAL135R, VAL136R, VAL137R, VAL22S, VAL79R, VAL91R
• T-X: ALA135T, ALA18X, ALA29X, ASN59X, ASP133T, GLN34X, GLN64T, GLU100T, GLU27X, GLU30X, GLU63T, ILE134T, ILE51X, ILE58X, ILE62T, ILE66T, LEU101T, LEU132T, LEU17X, LEU21X, LEU28X, LEU36X, LEU55X, LYS25X, LYS26X, LYS32X, LYS60T, PRO65T, THR56X, THR67T, TYR59T, VAL22X, VAL33X, VAL54X, VAL57X