1S1H

structure of the ribosomal 80s-eef2-sordarin complex from yeast obtained by docking atomic models for rna and protein components into a 11.7 a cryo-em map. this file, 1s1h, contains 40s subunit. the 60s ribosomal subunit is in file 1s1i.

• Total interactions analyzed: 136
• Total true interactions: 15
• Strongest Interaction:
  • Chains: B-E
  • Int. Res.: 45
  • Norm. En. per Res.: -0.6236
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
T-L	0.0	-0.093	142.052	141.959	32	19	0	2059	0	16	17
B-E	0.0	0.0	-28.0621	-28.0621	45	5	2	2682	0	3	7
B-H	-60.5368	-0.9576	668.624	607.1297	55	145	1	5256	0	15	10
C-E	0.0	0.0	-0.0781	-0.0781	8	0	0	25	0	1	1
C-J	0.0	-3.7489	-2.3574	-6.1063	20	7	0	655	0	9	4
C-N	0.0	1.0277	-4.0124	-2.9847	38	23	3	2335	0	19	14
D-E	-15.2837	-10.7649	317.386	291.3374	32	83	0	2802	0	18	13
D-H	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	1
E-H	-205.2888	0.0	3404.11	3198.8212	97	561	9	16196	0	6	18
G-I	-19.3251	-40.3931	539.006	479.2878	47	50	3	2975	3	19	26
G-K	-23.0766	2.1416	139.623	118.688	16	61	0	876	0	0	4
G-M	0.0	7.1966	-0.557	6.6396	2	0	0	66	0	2	5
I-J	0.0	0.0	-0.3129	-0.3129	7	0	0	62	0	2	3
J-N	-62.2351	-1.7553	5181.12	5117.1295	47	728	0	14771	3	14	19
M-S	-98.3371	-4.4836	474.501	371.6803	48	149	2	5306	0	18	17

Interface residues

• T-L: ALA498T, ASN497T, ASN499T, ASN99L, ASP100L, ASP500T, ASP639T, ASP97L, GLN75L, GLU101L, GLU506T, GLU98L, GLY51L, HIS528T, ILE52L, LEU132L, LEU501T, LEU504T, LEU54L, LEU93L, LYS503T, LYS509T, LYS50L, LYS672T, MET522T, PHE95L, PRO502T, SER131L, VAL102L, VAL495T, VAL505T, VAL53L
• B-E: ALA117E, ALA123E, ALA126E, ALA99E, ARG118B, ARG125E, ARG96E, ASN108B, ASN139B, GLU116B, GLU119E, GLY113E, GLY122E, GLY127E, ILE110B, ILE114E, ILE129E, ILE130E, ILE136E, ILE140B, LEU112E, LEU133E, LEU210E, LYS115B, LYS115E, LYS118E, LYS132E, LYS211E, LYS98E, PHE106B, PHE114B, PHE214E, PHE97E, PRO117B, PRO137E, PRO141B, SER113B, SER134E, THR107B, THR111B, THR116E, TYR109B, TYR137B, VAL135E, VAL138B
• B-H: ALA135B, ALA158B, ALA16H, ARG118B, ARG22H, ARG67H, ASN139B, ASN15H, ASN65H, ASN69H, ASP156B, CYS71H, GLN23H, GLN29B, GLN32B, GLU116B, GLU134B, GLU153B, GLU17H, GLU33B, GLY20H, GLY66H, GLY72H, HIS31B, ILE140B, ILE143B, ILE62B, ILE66B, LEU119B, LEU58B, LEU64H, LEU68H, LYS133B, LYS18H, LYS21H, LYS55B, LYS70H, PHE154B, PRO117B, PRO141B, PRO151B, PRO160B, PRO34B, SER136B, SER152B, THR19H, TYR137B, TYR35B, VAL120B, VAL138B, VAL142B, VAL155B, VAL157B, VAL24H, VAL30B
• C-E: ALA91E, ARG115C, ARG123C, GLN93E, LYS118E, LYS150C, PHE151C, TYR119C
• C-J: ARG39C, ASP113J, GLN33J, GLU109J, GLU115J, GLU46C, GLY111J, ILE108J, LYS6C, PRO110J, PRO71J, SER5C, THR104J, THR107J, THR41C, VAL112J, VAL114J, VAL11C, VAL37J, VAL40C
• C-N: ALA12C, ALA170C, ALA18C, ARG21N, ARG31N, ARG8C, ASN21C, ASN36N, ASN47N, ASP13C, ASP34N, ASP48N, CYS20N, GLU19C, GLU22C, GLU37C, GLY14C, LEU10C, LEU35N, LYS184C, LYS32N, LYS45N, LYS6C, LYS7C, LYS9C, PHE16C, SER5C, THR169C, THR171C, TYR17C, TYR33C, TYR33N, VAL11C, VAL15C, VAL22N, VAL30N, VAL36C, VAL38C
• D-E: ALA171E, ALA179E, ARG173E, ARG57D, ASP194E, ASP89D, ASP94D, GLN188E, GLU193E, GLU88D, GLY174E, GLY176E, HIS151E, ILE169E, ILE177E, LEU86D, LEU93D, LYS184E, LYS90D, LYS91D, LYS92D, PRO170E, PRO172E, PRO181E, SER152E, SER175E, SER87D, TYR196E, TYR95D, VAL178E, VAL195E, VAL96D
• D-H: ARG96H, LYS90D
• E-H: ALA154E, ALA171E, ALA190E, ALA212E, ALA213E, ALA216E, ALA95H, ARG116H, ARG139E, ARG140E, ARG167E, ARG67H, ARG77H, ARG96H, ASN200E, ASN219E, ASN65H, ASN69H, ASN79H, ASP111H, CYS161E, CYS71H, GLN149E, GLN198E, GLN97H, GLU113H, GLU114H, GLY111E, GLY126H, GLY159E, GLY162E, GLY218E, GLY222E, GLY44H, GLY72H, GLY99H, HIS112H, HIS43H, ILE124H, ILE136E, ILE138E, ILE169E, ILE217E, ILE46H, ILE74H, LEU112E, LEU133E, LEU153E, LEU168E, LEU186E, LEU187E, LEU210E, LEU68H, LEU92H, LEU93H, LYS156E, LYS160E, LYS18H, LYS211E, LYS42H, LYS70H, LYS87H, MET40H, PHE127H, PHE214E, PHE78H, PHE98H, PRO137E, PRO170E, PRO172E, PRO76H, PRO94H, SER134E, SER152E, SER163E, SER75H, THR155E, THR157E, THR158E, THR165E, THR197E, THR220E, TYR100H, TYR129H, TYR196E, TYR221E, TYR45H, VAL101H, VAL128H, VAL135E, VAL166E, VAL183E, VAL192E, VAL195E, VAL215E, VAL73H, VAL80H
• G-I: ALA109G, ALA84G, ARG111G, ARG113I, ARG121I, ARG134I, ARG44I, ARG80G, ARG81I, ASN78G, ASN94G, ASP112I, CYS86G, GLN85G, GLU39I, GLU41I, GLU49I, GLY104G, HIS115G, HIS73I, ILE112G, ILE113G, ILE42I, ILE88G, ILE89G, LEU107G, LEU43I, LEU52I, LEU53I, LYS106G, LYS108G, LYS114G, LYS46I, LYS79G, LYS83G, MET97G, PHE45I, PHE81G, PRO40I, PRO87G, SER110I, THR109I, TYR111I, TYR76G, TYR78I, VAL110G, VAL74I
• G-K: ALA153G, ALA154G, ARG155G, ARG224G, GLN64K, GLY149G, GLY150G, GLY151G, GLY152G, GLY94K, LYS91K, MET60K, PRO93K, THR90K, THR92K, TYR57K
• G-M: ARG184G, HIS55M
• I-J: ARG122I, LYS64J, PHE128I, PRO125I, SER66J, THR81J, TRP79J
• J-N: ALA46N, ARG21N, ARG31N, ARG39N, ARG43N, ARG68J, ASN36N, ASN47N, ASN72J, ASP34N, ASP48N, CYS20N, CYS23N, CYS38N, CYS41N, GLN40N, GLU44N, GLU74J, GLU80J, GLY28N, GLY73J, GLY75J, HIS26N, ILE37N, ILE65J, LEU29N, LEU35N, LYS32N, LYS45N, LYS69J, LYS77J, PHE42N, PRO71J, SER24N, SER25N, SER66J, SER76J, THR27N, THR67J, THR70J, THR78J, THR81J, TRP79J, TYR33N, TYR82J, VAL22N, VAL30N
• M-S: ALA121M, ARG108S, ARG120M, ARG123M, ARG126M, ARG132M, ARG134M, ARG47S, ARG81S, ASN103S, ASN98S, GLN136M, GLU106S, GLU110S, GLU118S, GLY117S, GLY124M, GLY130M, GLY135M, GLY142M, HIS114S, HIS122M, HIS137M, ILE119M, ILE121S, ILE125M, ILE85S, ILE96S, LEU116M, LEU116S, LEU131M, LYS100S, LYS139M, MET111S, PHE119S, PRO109S, PRO125S, SER120S, THR122S, THR124S, THR138M, THR140M, THR141M, TRP129M, TYR115S, TYR123S, VAL105S, VAL133M