1RYY

acetobacter turbidans alpha-amino acid ester hydrolase y206a mutant

• Total interactions analyzed: 28
• Total true interactions: 13
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 178
  • Norm. En. per Res.: -3.619
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-21.4145	-97.7431	-156.305	-275.4626	93	8	0	5563	10	49	53
A-C	-65.2683	-78.2305	-500.69	-644.1888	178	11	8	19278	8	32	32
A-D	-29.2608	-102.3123	-331.552	-463.1251	141	11	3	12777	5	67	76
B-C	-29.4321	-102.674	-330.38	-462.4861	140	12	3	12695	4	68	76
B-D	-67.013	-77.0531	-486.899	-630.9651	175	11	8	18995	8	34	29
C-D	-23.8192	-87.5968	-147.255	-258.6711	91	5	0	5305	11	49	52
D-E	-9.9064	-19.2983	-11.8108	-41.0155	30	1	0	792	1	23	27
E-F	-22.1309	-93.6559	-155.991	-271.7778	90	7	0	5510	10	48	53
E-G	-61.8848	-74.7721	-497.99	-634.6469	176	7	8	19324	8	32	29
E-H	-29.3941	-102.4411	-328.904	-460.7392	141	11	2	12660	5	67	76
F-G	-32.5434	-102.1961	-335.358	-470.0975	142	14	3	12983	6	68	76
F-H	-63.2174	-74.9567	-499.393	-637.5671	177	12	8	19327	8	32	28
G-H	-25.2703	-98.7087	-147.431	-271.4099	88	5	0	5200	11	48	54

Interface residues

• A-B: ALA124A, ALA124B, ALA553A, ALA553B, ARG120A, ARG120B, ARG128A, ARG128B, ARG394A, ARG394B, ARG395A, ARG395B, ASN374A, ASN374B, ASN376A, ASN376B, ASP135A, ASP135B, ASP136A, ASP136B, ASP388A, ASP388B, ASP425A, ASP425B, ASP557A, ASP557B, ASP558A, ASP558B, GLN133A, GLN133B, GLN392A, GLN392B, GLN426A, GLN426B, GLU129A, GLU129B, GLU140A, GLU140B, GLU384A, GLU384B, GLU386A, GLU386B, GLY134A, GLY134B, GLY387A, GLY387B, GLY424A, GLY424B, HIS391A, HIS391B, LEU125A, LEU125B, LEU131A, LEU131B, LYS427A, LYS427B, LYS608A, LYS608B, MET127A, MET127B, MET554A, MET554B, PHE385A, PHE385B, PRO132A, PRO132B, PRO552A, PRO552B, PRO556A, PRO556B, PRO559A, PRO559B, SER378A, SER378B, THR126A, THR126B, THR379A, THR379B, THR389A, THR389B, THR555A, THR555B, TYR375A, TYR375B, TYR421A, TYR421B, VAL121A, VAL121B, VAL130A, VAL130B, VAL139A, VAL139B, VAL517B
• A-C: ALA124A, ALA124C, ALA260A, ALA260C, ALA272A, ALA272C, ALA291A, ALA291C, ALA304A, ALA304C, ALA310A, ALA310C, ALA63A, ALA63C, ARG151A, ARG151C, ARG164A, ARG164C, ARG261A, ARG261C, ARG269A, ARG269C, ARG270A, ARG270C, ARG301A, ARG301C, ARG73A, ARG73C, ASN119A, ASN119C, ASN123A, ASN123C, ASN171A, ASN171C, ASN265A, ASN265C, ASN277A, ASN277C, ASP159A, ASP159C, ASP266A, ASP266C, ASP271A, ASP271C, ASP294A, ASP294C, ASP309A, ASP309C, ASP51A, ASP51C, ASP60A, ASP60C, ASP74A, ASP74C, GLN257A, GLN257C, GLN290A, GLN290C, GLN295A, GLN295C, GLN300A, GLN300C, GLN315A, GLN315C, GLN56A, GLN56C, GLN71A, GLN71C, GLN72A, GLN72C, GLU129A, GLU129C, GLY152A, GLY152C, GLY158A, GLY158C, GLY168A, GLY168C, GLY262A, GLY262C, GLY292A, GLY292C, GLY58A, GLY58C, HIS303A, HIS303C, HIS305A, HIS305C, HIS50A, HIS50C, ILE267A, ILE267C, ILE61A, ILE61C, LEU125A, LEU125C, LEU170A, LEU170C, LEU293A, LEU293C, LEU53A, LEU53C, LYS115A, LYS115C, LYS153A, LYS153C, MET127C, MET162A, MET162C, MET258A, MET258C, MET302A, MET302C, PHE254A, PHE254C, PHE287A, PHE287C, PHE298A, PHE298C, PHE311A, PHE311C, PRO122A, PRO122C, PRO165A, PRO165C, PRO169A, PRO169C, PRO172A, PRO172C, PRO268A, PRO268C, PRO297A, PRO297C, PRO52A, PRO52C, PRO62A, PRO62C, SER54A, SER54C, SER59A, SER59C, SER64A, SER64C, THR126A, THR126C, THR163A, THR163C, THR173A, THR173C, THR259A, THR259C, THR289A, THR289C, THR57A, THR57C, TRP299A, TRP299C, TRP312C, TYR154A, TYR154C, TYR160A, TYR160C, TYR296A, TYR296C, TYR75A, TYR75C, VAL121A, VAL121C, VAL130A, VAL130C, VAL161A, VAL161C, VAL255A, VAL255C, VAL55A, VAL55C, VAL65A, VAL65C
• A-D: ALA272A, ALA272D, ALA475A, ALA475D, ALA486A, ALA486D, ALA488A, ALA488D, ALA504A, ALA504D, ALA553A, ALA553D, ARG269A, ARG269D, ARG270A, ARG270D, ARG483A, ARG483D, ARG502A, ARG502D, ARG507A, ARG507D, ARG611A, ARG611D, ASN277A, ASN277D, ASP271A, ASP271D, ASP273A, ASP273D, ASP274A, ASP274D, ASP468A, ASP468D, ASP473A, ASP473D, ASP500A, ASP500D, ASP509A, ASP509D, ASP558A, ASP558D, GLN489A, GLN489D, GLN501A, GLN501D, GLN551A, GLN551D, GLN615A, GLN615D, GLU503A, GLU503D, GLU505A, GLU505D, GLU514A, GLU514D, GLU516A, GLU516D, GLU565A, GLU565D, GLY562A, GLY562D, GLY563A, GLY563D, HIS455A, HIS455D, HIS476A, HIS476D, ILE267A, ILE481A, ILE481D, LEU279A, LEU279D, LYS280A, LYS280D, LYS560A, LYS560D, MET554A, MET554D, MET561A, MET561D, MET613A, MET613D, PHE485A, PHE485D, PHE621A, PHE621D, PRO268A, PRO268D, PRO474A, PRO474D, PRO477A, PRO477D, PRO479A, PRO479D, PRO484A, PRO484D, PRO508A, PRO508D, PRO552A, PRO552D, PRO559A, PRO559D, SER469A, SER469D, SER472A, SER472D, SER482A, SER482D, SER506A, SER506D, SER619A, SER619D, THR276A, THR276D, THR512A, THR512D, THR515A, THR515D, THR555A, THR555D, TYR275A, TYR275D, TYR470A, TYR470D, TYR564A, TYR564D, VAL471A, VAL471D, VAL478A, VAL478D, VAL510A, VAL510D, VAL511A, VAL511D, VAL517A, VAL517D, VAL550A, VAL550D, VAL645A, VAL645D
• B-C: ALA272B, ALA272C, ALA475B, ALA475C, ALA486B, ALA486C, ALA488B, ALA488C, ALA504B, ALA504C, ALA553B, ALA553C, ARG269B, ARG269C, ARG270B, ARG270C, ARG483B, ARG483C, ARG502B, ARG502C, ARG507B, ARG507C, ARG611B, ARG611C, ASN277B, ASN277C, ASP271B, ASP271C, ASP273B, ASP273C, ASP274B, ASP274C, ASP468B, ASP468C, ASP473B, ASP473C, ASP500B, ASP500C, ASP509B, ASP509C, ASP558B, ASP558C, GLN489B, GLN489C, GLN501B, GLN501C, GLN551B, GLN551C, GLN615B, GLN615C, GLU503B, GLU503C, GLU505B, GLU505C, GLU514B, GLU514C, GLU516B, GLU516C, GLU565B, GLU565C, GLY562B, GLY562C, GLY563B, GLY563C, HIS455B, HIS455C, HIS476B, HIS476C, ILE267B, ILE267C, ILE481B, ILE481C, LEU279B, LEU279C, LYS280B, LYS280C, LYS560B, LYS560C, MET554B, MET554C, MET561B, MET561C, MET613B, MET613C, PHE485B, PHE485C, PHE621B, PHE621C, PRO268B, PRO268C, PRO474B, PRO474C, PRO477B, PRO477C, PRO479B, PRO479C, PRO484B, PRO484C, PRO508B, PRO508C, PRO552B, PRO552C, PRO559B, PRO559C, SER469B, SER469C, SER472B, SER472C, SER482B, SER482C, SER506B, SER506C, THR276B, THR276C, THR512B, THR512C, THR515B, THR515C, THR555B, THR555C, TYR275B, TYR275C, TYR470B, TYR470C, TYR564B, TYR564C, VAL471B, VAL471C, VAL478B, VAL478C, VAL510B, VAL510C, VAL511B, VAL511C, VAL517B, VAL517C, VAL550B, VAL550C, VAL645B, VAL645C
• B-D: ALA124B, ALA124D, ALA260B, ALA260D, ALA272B, ALA272D, ALA291B, ALA291D, ALA304B, ALA304D, ALA310B, ALA310D, ALA63B, ALA63D, ARG151B, ARG151D, ARG164B, ARG164D, ARG261B, ARG261D, ARG269B, ARG269D, ARG270B, ARG270D, ARG301B, ARG301D, ARG73B, ARG73D, ASN119B, ASN119D, ASN123B, ASN123D, ASN171B, ASN171D, ASN265B, ASN265D, ASN277B, ASN277D, ASP159B, ASP159D, ASP266B, ASP266D, ASP271B, ASP271D, ASP294B, ASP294D, ASP309B, ASP309D, ASP51B, ASP51D, ASP60B, ASP60D, ASP74B, ASP74D, GLN257B, GLN257D, GLN290B, GLN290D, GLN295B, GLN295D, GLN300B, GLN300D, GLN315B, GLN315D, GLN56B, GLN56D, GLN71B, GLN71D, GLN72B, GLN72D, GLU129B, GLU129D, GLY152B, GLY152D, GLY158B, GLY158D, GLY168B, GLY168D, GLY262B, GLY262D, GLY292B, GLY292D, GLY58B, GLY58D, HIS303B, HIS303D, HIS305B, HIS305D, HIS50B, HIS50D, ILE267B, ILE267D, ILE61B, ILE61D, LEU125B, LEU125D, LEU170B, LEU170D, LEU293B, LEU293D, LEU53B, LEU53D, LYS115B, LYS115D, LYS153B, LYS153D, MET162B, MET162D, MET258B, MET258D, MET302B, MET302D, PHE254B, PHE254D, PHE287B, PHE287D, PHE298B, PHE298D, PHE311B, PHE311D, PRO122B, PRO122D, PRO165B, PRO165D, PRO169B, PRO169D, PRO172B, PRO172D, PRO268B, PRO268D, PRO297B, PRO297D, PRO52B, PRO52D, PRO62B, PRO62D, SER54B, SER54D, SER59B, SER59D, SER64B, SER64D, THR126B, THR126D, THR163B, THR163D, THR173B, THR173D, THR259B, THR259D, THR289B, THR289D, THR57B, THR57D, TRP299B, TRP299D, TRP312B, TYR154B, TYR154D, TYR160B, TYR160D, TYR296B, TYR296D, TYR75B, TYR75D, VAL121B, VAL121D, VAL161B, VAL161D, VAL255B, VAL255D, VAL55B, VAL55D, VAL65B, VAL65D
• C-D: ALA124C, ALA124D, ALA553C, ALA553D, ARG120C, ARG120D, ARG128C, ARG128D, ARG394C, ARG394D, ARG395C, ARG395D, ASN374C, ASN374D, ASN376C, ASN376D, ASP135C, ASP135D, ASP136C, ASP136D, ASP388C, ASP388D, ASP425C, ASP425D, ASP557C, ASP557D, ASP558C, ASP558D, GLN133C, GLN133D, GLN392C, GLN392D, GLN426C, GLN426D, GLU129C, GLU129D, GLU140C, GLU140D, GLU384C, GLU384D, GLU386C, GLU386D, GLY134C, GLY134D, GLY387C, GLY387D, GLY424D, HIS391C, HIS391D, LEU125C, LEU125D, LEU131C, LEU131D, LYS427C, LYS427D, LYS608C, LYS608D, MET127C, MET127D, MET554C, MET554D, PHE385C, PHE385D, PRO132C, PRO132D, PRO552C, PRO552D, PRO556C, PRO556D, PRO559C, PRO559D, SER378C, SER378D, THR126C, THR126D, THR379C, THR379D, THR389C, THR389D, THR555C, THR555D, TYR375C, TYR375D, TYR421C, VAL121C, VAL121D, VAL130C, VAL130D, VAL139C, VAL139D, VAL517D
• D-E: ALA534D, ALA535D, ALA591D, ARG578D, ARG578E, ASP465E, ASP580D, ASP580E, ASP590D, GLN313D, GLN588D, GLN588E, GLU656D, GLY466E, HIS594D, HIS594E, HIS596D, HIS651D, HIS651E, LEU593D, LYS579D, LYS579E, LYS583D, LYS583E, LYS655D, LYS655E, PHE533D, PHE533E, PHE581D, THR592D
• E-F: ALA124E, ALA124F, ALA553E, ALA553F, ARG120E, ARG120F, ARG128E, ARG128F, ARG394E, ARG394F, ARG395E, ARG395F, ASN374E, ASN374F, ASN376E, ASN376F, ASP135E, ASP135F, ASP136E, ASP136F, ASP388E, ASP388F, ASP425E, ASP425F, ASP557E, ASP557F, ASP558E, ASP558F, GLN133E, GLN133F, GLN392E, GLN392F, GLN426E, GLN426F, GLU129E, GLU129F, GLU140E, GLU140F, GLU384E, GLU384F, GLU386E, GLU386F, GLY134E, GLY134F, GLY387E, GLY387F, GLY424E, HIS391E, HIS391F, LEU125E, LEU125F, LEU131E, LEU131F, LYS427E, LYS427F, LYS608E, LYS608F, MET127E, MET127F, MET554E, MET554F, PHE385E, PHE385F, PRO132E, PRO132F, PRO552E, PRO552F, PRO556E, PRO556F, PRO559E, PRO559F, SER378E, SER378F, THR126E, THR126F, THR379E, THR379F, THR389E, THR389F, THR555E, THR555F, TYR375E, TYR375F, TYR421F, VAL121E, VAL121F, VAL130E, VAL130F, VAL139E, VAL139F
• E-G: ALA124E, ALA124G, ALA260E, ALA260G, ALA272E, ALA272G, ALA291E, ALA291G, ALA304E, ALA304G, ALA310E, ALA310G, ALA63E, ALA63G, ARG151E, ARG151G, ARG164E, ARG164G, ARG261E, ARG261G, ARG269E, ARG269G, ARG270E, ARG270G, ARG301E, ARG301G, ARG73E, ARG73G, ASN119E, ASN119G, ASN123E, ASN123G, ASN171E, ASN171G, ASN265E, ASN265G, ASN277E, ASN277G, ASP159E, ASP159G, ASP266E, ASP266G, ASP271E, ASP271G, ASP294G, ASP309E, ASP309G, ASP51E, ASP51G, ASP60E, ASP60G, ASP74E, ASP74G, GLN257E, GLN257G, GLN290E, GLN290G, GLN295E, GLN295G, GLN300E, GLN300G, GLN315E, GLN315G, GLN56E, GLN56G, GLN71E, GLN71G, GLN72E, GLN72G, GLU129E, GLU129G, GLY152E, GLY152G, GLY158E, GLY158G, GLY168E, GLY168G, GLY262E, GLY262G, GLY292E, GLY292G, GLY58E, GLY58G, HIS303E, HIS303G, HIS305E, HIS305G, HIS50E, HIS50G, ILE267E, ILE267G, ILE61E, ILE61G, LEU125E, LEU125G, LEU170E, LEU170G, LEU293E, LEU293G, LEU53E, LEU53G, LYS115E, LYS115G, LYS153E, LYS153G, MET162E, MET162G, MET258E, MET258G, MET302E, MET302G, PHE254E, PHE254G, PHE287E, PHE287G, PHE298E, PHE298G, PHE311E, PHE311G, PRO122E, PRO122G, PRO165E, PRO165G, PRO169E, PRO169G, PRO172E, PRO172G, PRO268E, PRO268G, PRO297E, PRO297G, PRO52E, PRO52G, PRO62E, PRO62G, SER54E, SER54G, SER59E, SER59G, SER64E, SER64G, THR126E, THR126G, THR163E, THR163G, THR173E, THR173G, THR259E, THR259G, THR289E, THR289G, THR57E, THR57G, TRP299E, TRP299G, TRP312E, TRP312G, TYR154E, TYR154G, TYR160E, TYR160G, TYR296E, TYR296G, TYR75E, TYR75G, VAL121E, VAL121G, VAL130G, VAL161E, VAL161G, VAL255E, VAL255G, VAL55E, VAL55G, VAL65E, VAL65G
• E-H: ALA272E, ALA272H, ALA475E, ALA475H, ALA486E, ALA486H, ALA488E, ALA488H, ALA504E, ALA504H, ALA553E, ALA553H, ARG269E, ARG269H, ARG270E, ARG270H, ARG483E, ARG483H, ARG502E, ARG502H, ARG507E, ARG507H, ARG611E, ARG611H, ASN277E, ASN277H, ASP271E, ASP271H, ASP273E, ASP273H, ASP274E, ASP274H, ASP468E, ASP468H, ASP473E, ASP473H, ASP500E, ASP500H, ASP509E, ASP509H, ASP558E, ASP558H, GLN489E, GLN489H, GLN501E, GLN501H, GLN551E, GLN551H, GLN615E, GLN615H, GLU503E, GLU503H, GLU505E, GLU505H, GLU514E, GLU514H, GLU516E, GLU516H, GLU565E, GLU565H, GLY562E, GLY562H, GLY563E, GLY563H, HIS455E, HIS455H, HIS476E, HIS476H, ILE267H, ILE481E, ILE481H, LEU279E, LEU279H, LYS280E, LYS280H, LYS560E, LYS560H, MET554E, MET554H, MET561E, MET561H, MET613E, MET613H, PHE485E, PHE485H, PHE621E, PHE621H, PRO268E, PRO268H, PRO474E, PRO474H, PRO477E, PRO477H, PRO479E, PRO479H, PRO484E, PRO484H, PRO508E, PRO508H, PRO552E, PRO552H, PRO556H, PRO559E, PRO559H, SER469E, SER469H, SER472E, SER472H, SER482E, SER482H, SER506E, SER506H, SER619H, THR276E, THR276H, THR512E, THR512H, THR515E, THR515H, THR555E, THR555H, TYR275E, TYR275H, TYR470E, TYR470H, TYR564E, TYR564H, VAL471E, VAL471H, VAL478E, VAL478H, VAL510E, VAL510H, VAL511E, VAL511H, VAL517E, VAL517H, VAL550E, VAL550H, VAL645E, VAL645H
• F-G: ALA272F, ALA272G, ALA475F, ALA475G, ALA486F, ALA486G, ALA488F, ALA488G, ALA504F, ALA504G, ALA553F, ALA553G, ARG269F, ARG269G, ARG270F, ARG270G, ARG483F, ARG483G, ARG492F, ARG502F, ARG502G, ARG507F, ARG507G, ARG611F, ARG611G, ASN277F, ASN277G, ASP271F, ASP271G, ASP273F, ASP273G, ASP274F, ASP274G, ASP468F, ASP468G, ASP473F, ASP473G, ASP500F, ASP500G, ASP509F, ASP509G, ASP558F, ASP558G, GLN489F, GLN489G, GLN501F, GLN501G, GLN551F, GLN551G, GLN615F, GLN615G, GLU503F, GLU503G, GLU505F, GLU505G, GLU514F, GLU514G, GLU516F, GLU516G, GLU565F, GLU565G, GLY562F, GLY562G, GLY563F, GLY563G, HIS455F, HIS455G, HIS476F, HIS476G, ILE267F, ILE267G, ILE481F, ILE481G, LEU279F, LEU279G, LYS280F, LYS280G, LYS560F, LYS560G, MET554F, MET554G, MET561F, MET561G, MET613F, MET613G, PHE485F, PHE485G, PHE621F, PHE621G, PRO268F, PRO268G, PRO474F, PRO474G, PRO477F, PRO477G, PRO479F, PRO479G, PRO484F, PRO484G, PRO508F, PRO508G, PRO552F, PRO552G, PRO559F, PRO559G, SER469F, SER469G, SER472F, SER472G, SER482F, SER482G, SER506F, SER506G, SER619F, THR276F, THR276G, THR512F, THR512G, THR515F, THR515G, THR555F, THR555G, TYR275F, TYR275G, TYR470F, TYR470G, TYR564F, TYR564G, VAL471F, VAL471G, VAL478F, VAL478G, VAL510F, VAL510G, VAL511F, VAL511G, VAL517F, VAL517G, VAL550F, VAL550G, VAL645F, VAL645G
• F-H: ALA124F, ALA124H, ALA260F, ALA260H, ALA272F, ALA272H, ALA291F, ALA291H, ALA304F, ALA304H, ALA310F, ALA310H, ALA63F, ALA63H, ARG151F, ARG151H, ARG164F, ARG164H, ARG261F, ARG261H, ARG269F, ARG269H, ARG270F, ARG270H, ARG301F, ARG301H, ARG73F, ARG73H, ASN119F, ASN119H, ASN123F, ASN123H, ASN171F, ASN171H, ASN265F, ASN265H, ASN277F, ASN277H, ASP159F, ASP159H, ASP266F, ASP266H, ASP271F, ASP271H, ASP294F, ASP294H, ASP309F, ASP309H, ASP51F, ASP51H, ASP60F, ASP60H, ASP74F, ASP74H, GLN257F, GLN257H, GLN290F, GLN290H, GLN295F, GLN295H, GLN300F, GLN300H, GLN315F, GLN315H, GLN56F, GLN56H, GLN71F, GLN71H, GLN72F, GLN72H, GLU129F, GLU129H, GLY152F, GLY152H, GLY158F, GLY158H, GLY168F, GLY168H, GLY262F, GLY262H, GLY264F, GLY292F, GLY292H, GLY58F, GLY58H, HIS303F, HIS303H, HIS305F, HIS305H, HIS50F, HIS50H, ILE267F, ILE267H, ILE61F, ILE61H, LEU125F, LEU125H, LEU170F, LEU170H, LEU293F, LEU293H, LEU53F, LEU53H, LYS115F, LYS115H, LYS153F, LYS153H, MET162F, MET162H, MET258F, MET258H, MET302F, MET302H, PHE254F, PHE254H, PHE287F, PHE287H, PHE298F, PHE298H, PHE311F, PHE311H, PRO122F, PRO122H, PRO165F, PRO165H, PRO169F, PRO169H, PRO172F, PRO172H, PRO268F, PRO268H, PRO297F, PRO297H, PRO52F, PRO52H, PRO62F, PRO62H, SER54F, SER54H, SER59F, SER59H, SER64F, SER64H, THR126F, THR126H, THR163F, THR163H, THR173F, THR173H, THR259F, THR259H, THR289F, THR289H, THR57F, THR57H, TRP299F, TRP299H, TRP312H, TYR154F, TYR154H, TYR160F, TYR160H, TYR296F, TYR296H, TYR75F, TYR75H, VAL121F, VAL121H, VAL130H, VAL161F, VAL161H, VAL255F, VAL255H, VAL55F, VAL55H, VAL65F, VAL65H
• G-H: ALA124G, ALA124H, ALA553G, ALA553H, ARG120G, ARG120H, ARG128G, ARG128H, ARG394G, ARG394H, ARG395G, ARG395H, ASN374H, ASN376G, ASN376H, ASP135G, ASP135H, ASP136G, ASP136H, ASP388G, ASP388H, ASP425G, ASP425H, ASP557G, ASP557H, ASP558G, ASP558H, GLN133G, GLN133H, GLN392G, GLN392H, GLN426G, GLN426H, GLU129G, GLU129H, GLU140G, GLU140H, GLU384G, GLU384H, GLU386G, GLU386H, GLY134G, GLY134H, GLY387G, GLY387H, HIS391G, HIS391H, LEU125G, LEU125H, LEU131G, LEU131H, LYS427G, LYS427H, LYS608G, LYS608H, MET127G, MET127H, MET554G, MET554H, PHE385G, PHE385H, PRO132G, PRO132H, PRO552G, PRO552H, PRO556G, PRO556H, PRO559G, PRO559H, SER378G, SER378H, THR126G, THR126H, THR379G, THR379H, THR389G, THR389H, THR555G, THR555H, TYR375G, TYR375H, TYR421H, VAL121G, VAL121H, VAL130G, VAL130H, VAL139G, VAL139H