1RV6

crystal structure of plgf in complex with domain 2 of vegfr1

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: W-X
  • Int. Res.: 56
  • Norm. En. per Res.: -3.0292
• Hub Node: V(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
V-W	-88.9092	-94.3983	834.754	651.4465	112	24	6	14685	7	18	24
V-X	0.0	0.0	-40.6121	-40.6121	30	2	2	2259	0	5	8
V-Y	-14.6647	-27.5553	-123.724	-165.944	57	2	4	5600	2	14	11
W-X	-17.5567	-28.8966	-123.18	-169.6332	56	5	4	5626	2	16	12
W-Y	0.0	0.0	-41.4634	-41.4634	32	6	4	2353	0	4	8

Interface residues

• V-W: ARG31V, ARG31W, ARG35V, ARG35W, ARG39V, ARG39W, ASN83V, ASP42V, ASP42W, ASP71V, ASP71W, CYS34V, CYS34W, CYS59V, CYS59W, CYS65V, CYS65W, CYS68V, CYS68W, CYS69V, CYS69W, CYS76V, CYS76W, GLN106V, GLN106W, GLN26V, GLN26W, GLN87V, GLN87W, GLU101V, GLU101W, GLU21W, GLU27V, GLU27W, GLU38V, GLU38W, GLU72V, GLU72W, GLY30V, GLY30W, GLY67V, GLY67W, GLY70V, GLY70W, ILE91V, ILE91W, LEU102V, LEU102W, LEU37V, LEU37W, LEU40V, LEU40W, LEU62V, LEU62W, LEU63V, LEU63W, LEU88V, LEU88W, LEU89V, LEU89W, LYS90V, LYS90W, MET54V, MET54W, MET86V, MET86W, PHE104V, PHE104W, PHE25V, PHE25W, PHE55V, PHE55W, PRO24V, PRO24W, PRO57V, PRO57W, SER32V, SER32W, SER56V, SER56W, SER58V, SER58W, SER61V, SER61W, THR103V, THR103W, THR66V, THR66W, THR85V, THR85W, TRP29V, TRP29W, TYR33V, TYR33W, TYR99V, TYR99W, VAL100V, VAL100W, VAL22V, VAL22W, VAL23V, VAL23W, VAL28V, VAL28W, VAL41V, VAL41W, VAL43V, VAL43W, VAL60V, VAL60W, VAL84V, VAL84W
• V-X: ARG224X, ARG92V, ARG96V, GLN87V, GLU101V, GLU141X, GLU144X, GLY94V, HIS147X, HIS223X, ILE142X, ILE145X, ILE146X, ILE91V, LEU204X, LEU221X, LEU88V, LEU89V, LYS90V, MET54V, PHE55V, PRO143X, PRO57V, PRO97V, SER56V, SER58V, SER98V, THR222X, TYR99V, VAL100V
• V-Y: ARG109V, ARG113V, ARG224Y, ARG31V, ARG35V, ASN219Y, ASN73V, ASP175Y, ASP71V, CYS110V, CYS112V, CYS34V, CYS69V, GLN26V, GLU111V, GLU141Y, GLU150Y, GLU201Y, GLU27V, GLU72V, GLY203Y, GLY30V, GLY70V, HIS223Y, ILE142Y, ILE145Y, ILE202Y, LEU115V, LEU174Y, LEU204Y, LEU205Y, LEU221Y, LEU74V, LYS171Y, LYS200Y, LYS217Y, MET148Y, PHE172Y, PHE25V, PRO114V, PRO143Y, PRO173Y, PRO24V, SER140Y, SER32V, THR198Y, THR206Y, THR218Y, THR222Y, TRP29V, TYR139Y, TYR199Y, TYR220Y, TYR33V, VAL22V, VAL23V, VAL79V
• W-X: ARG109W, ARG113W, ARG224X, ARG31W, ARG35W, ASN219X, ASN73W, ASP175X, ASP71W, CYS110W, CYS112W, CYS34W, CYS69W, GLN26W, GLU111W, GLU141X, GLU150X, GLU201X, GLU27W, GLU72W, GLY203X, GLY30W, GLY70W, HIS223X, HIS75W, ILE142X, ILE145X, ILE202X, LEU115W, LEU174X, LEU204X, LEU205X, LEU221X, LEU74W, LYS171X, LYS200X, LYS217X, MET148X, PHE172X, PHE25W, PRO114W, PRO143X, PRO173X, PRO24W, SER140X, SER32W, THR198X, THR206X, THR218X, THR222X, TRP29W, TYR139X, TYR199X, TYR220X, TYR33W, VAL79W
• W-Y: ARG224Y, ARG92W, ARG96W, ASP95W, GLN87W, GLU141Y, GLU144Y, GLY203Y, HIS147Y, HIS223Y, ILE142Y, ILE145Y, ILE146Y, ILE91W, LEU204Y, LEU221Y, LEU88W, LEU89W, LYS90W, MET54W, PHE55W, PRO143Y, PRO57W, PRO97W, SER140Y, SER56W, SER58W, SER98W, THR222Y, TYR220Y, TYR99W, VAL100W