1RG9

s-adenosylmethionine synthetase complexed with sam and ppnp

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 47
  • Norm. En. per Res.: -4.955
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-143.7299	-99.2545	-746.265	-989.2494	297	42	13	31361	12	83	79
A-C	-57.6212	-78.607	-96.6556	-232.8838	47	10	7	3543	6	8	9
A-D	-7.5477	3.302	-104.936	-109.1817	53	8	1	4503	0	10	7
B-C	0.0	5.4017	-105.334	-99.9323	52	7	1	4563	0	10	7
B-D	-61.5903	-78.1525	-95.8933	-235.6361	48	9	7	3536	6	8	9
C-D	-179.8775	-92.7287	-805.827	-1078.4332	307	59	13	33492	14	89	82

Interface residues

• A-B: ALA116A, ALA116B, ALA141A, ALA141B, ALA164A, ALA164B, ALA182A, ALA182B, ALA19A, ALA19B, ALA1A, ALA1B, ALA255A, ALA255B, ALA261A, ALA261B, ALA301A, ALA301B, ALA305A, ALA305B, ALA40A, ALA40B, ALA94A, ALA94B, ARG108A, ARG108B, ARG229A, ARG229B, ARG244A, ARG244B, ARG256A, ARG256B, ARG293A, ARG293B, ASN103A, ASN103B, ASN225A, ASN225B, ASP101A, ASP101B, ASP107A, ASP107B, ASP118A, ASP118B, ASP16A, ASP16B, ASP181A, ASP181B, ASP20A, ASP20B, ASP238A, ASP238B, ASP249A, ASP249B, ASP271A, ASP271B, CYS239A, CYS239B, CYS41A, CYS41B, GLN104A, GLN104B, GLN119A, GLN119B, GLN167A, GLN167B, GLN188A, GLN188B, GLN195A, GLN195B, GLN297A, GLN297B, GLN98A, GLN98B, GLU295A, GLU295B, GLU306A, GLU306B, GLU313A, GLU313B, GLU318A, GLU318B, GLU323A, GLU323B, GLU42A, GLU42B, GLU55A, GLU55B, GLU8A, GLU8B, GLY105A, GLY105B, GLY115A, GLY115B, GLY117A, GLY117B, GLY120A, GLY120B, GLY228A, GLY228B, GLY233A, GLY233B, GLY237A, GLY237B, GLY240A, GLY240B, GLY243A, GLY243B, GLY252A, GLY252B, GLY253A, GLY253B, GLY258A, GLY258B, GLY259A, GLY259B, GLY260A, GLY260B, GLY264A, GLY264B, GLY303A, GLY303B, GLY48A, GLY48B, GLY53A, GLY53B, GLY54A, GLY54B, GLY96A, GLY96B, HIS14A, HIS14B, HIS189A, HIS189B, HIS257A, HIS257B, HIS3A, HIS3B, ILE102A, ILE102B, ILE138A, ILE138B, ILE224A, ILE224B, ILE232A, ILE232B, ILE246A, ILE246B, ILE247A, ILE247B, ILE302A, ILE302B, ILE310A, ILE310B, ILE56A, ILE56B, ILE95A, ILE95B, LEU121A, LEU121B, LEU185A, LEU185B, LEU241A, LEU241B, LEU4A, LEU4B, LEU51A, LEU51B, LEU92A, LEU92B, LYS165A, LYS165B, LYS221A, LYS221B, LYS245A, LYS245B, LYS265A, LYS265B, LYS2A, LYS2B, LYS46A, LYS46B, LYS97A, LYS97B, MET122A, MET122B, MET236A, MET236B, MET254A, MET254B, MET311A, MET311B, MET49A, MET49B, PHE123A, PHE123B, PHE170A, PHE170B, PHE222A, PHE222B, PHE223A, PHE223B, PHE230A, PHE230B, PHE262A, PHE262B, PHE315A, PHE315B, PHE5A, PHE5B, PRO100A, PRO100B, PRO137A, PRO137B, PRO226A, PRO226B, PRO235A, PRO235B, PRO307A, PRO307B, SER11A, SER11B, SER166A, SER166B, SER186A, SER186B, SER23A, SER23B, SER263A, SER263B, SER299A, SER299B, SER309A, SER309B, SER322A, SER322B, SER7A, SER7B, SER93A, SER93B, SER99A, SER99B, SER9A, SER9B, THR169A, THR169B, THR227A, THR227B, THR242A, THR242B, THR250B, THR308A, THR308B, THR326A, THR326B, THR43A, THR43B, THR47A, THR47B, THR6A, THR6B, TYR125A, TYR125B, TYR172A, TYR172B, TYR251A, TYR251B, TYR300A, TYR300B, TYR44A, TYR44B, VAL106A, VAL106B, VAL10A, VAL10B, VAL145A, VAL145B, VAL168A, VAL168B, VAL183A, VAL183B, VAL184A, VAL184B, VAL231A, VAL231B, VAL248A, VAL248B, VAL298A, VAL298B, VAL304A, VAL304B, VAL312A, VAL312B, VAL45A, VAL45B, VAL52A, VAL52B
• A-C: ALA60A, ALA60C, ALA90A, ALA90C, ALA94A, ALA94C, ARG69A, ARG69C, ASP63A, ASP63C, GLN33A, GLN33C, GLU55A, GLU55C, GLU65A, GLU65C, GLU66A, GLU66C, GLY53A, GLY53C, GLY96A, GLY96C, ILE56A, ILE56C, ILE64A, ILE64C, ILE67A, ILE67C, ILE95A, ILE95C, LEU51A, LEU51C, LEU92A, LEU92C, LYS97A, LYS97C, SER93A, SER93C, TRP61A, TRP61C, VAL50A, VAL52A, VAL52C, VAL62A, VAL62C, VAL91A, VAL91C
• A-D: ALA86A, ALA86D, ALA90A, ALA90D, ARG69A, ARG69D, ASN87A, ASN87D, ASP81A, ASP81D, ASP85A, ASP85D, CYS89A, CYS89D, GLU65A, GLU65D, GLY48A, GLY48D, GLY83A, GLY83D, HIS79A, HIS79D, LEU51A, LEU51D, LEU92A, LEU92D, LYS46A, LYS46D, MET236A, MET236D, MET49A, MET49D, MET82A, MET82D, PHE84A, PHE84D, PRO235A, SER80A, SER80D, SER88A, SER88D, SER93A, SER93D, THR47A, THR47D, TYR44A, TYR44D, VAL50A, VAL50D, VAL78A, VAL78D, VAL91A, VAL91D
• B-C: ALA86B, ALA86C, ALA90B, ALA90C, ARG69B, ARG69C, ASN87B, ASN87C, ASP81B, ASP81C, ASP85B, ASP85C, CYS89B, CYS89C, GLU65B, GLU65C, GLY48B, GLY48C, GLY83B, GLY83C, HIS79B, HIS79C, LEU51B, LEU51C, LEU92B, LEU92C, LYS46B, LYS46C, MET236B, MET236C, MET49B, MET49C, MET82B, MET82C, PHE84B, PHE84C, SER80B, SER80C, SER88B, SER88C, SER93B, SER93C, THR47B, THR47C, TYR44B, TYR44C, VAL50B, VAL50C, VAL78B, VAL78C, VAL91B, VAL91C
• B-D: ALA60B, ALA60D, ALA90B, ALA90D, ALA94B, ALA94D, ARG69B, ARG69D, ASP63B, ASP63D, GLN33B, GLN33D, GLU55B, GLU55D, GLU65B, GLU65D, GLU66B, GLU66D, GLY53B, GLY53D, GLY96B, GLY96D, ILE56B, ILE56D, ILE64B, ILE64D, ILE67B, ILE67D, ILE95B, ILE95D, LEU51B, LEU51D, LEU92B, LEU92D, LYS97B, LYS97D, SER93B, SER93D, TRP61B, TRP61D, VAL50B, VAL50D, VAL52B, VAL52D, VAL62B, VAL62D, VAL91B, VAL91D
• C-D: ALA116C, ALA116D, ALA141C, ALA141D, ALA164C, ALA164D, ALA182C, ALA182D, ALA19C, ALA19D, ALA1C, ALA1D, ALA255C, ALA255D, ALA261C, ALA261D, ALA301C, ALA301D, ALA305C, ALA305D, ALA40C, ALA40D, ALA94C, ALA94D, ARG108C, ARG108D, ARG229C, ARG229D, ARG244C, ARG244D, ARG256C, ARG256D, ARG293C, ARG293D, ASN103C, ASN103D, ASN225C, ASN225D, ASP101C, ASP101D, ASP107C, ASP107D, ASP118C, ASP118D, ASP163C, ASP163D, ASP16C, ASP16D, ASP181C, ASP181D, ASP20C, ASP20D, ASP238C, ASP238D, ASP249C, ASP249D, ASP271C, ASP271D, CYS239C, CYS239D, CYS41C, CYS41D, GLN104C, GLN104D, GLN119C, GLN119D, GLN167C, GLN167D, GLN188C, GLN188D, GLN195C, GLN195D, GLN297C, GLN297D, GLN98C, GLN98D, GLU295C, GLU295D, GLU306C, GLU306D, GLU313C, GLU313D, GLU318C, GLU318D, GLU323C, GLU323D, GLU42C, GLU42D, GLU55C, GLU55D, GLU8C, GLU8D, GLY105C, GLY105D, GLY115C, GLY115D, GLY117C, GLY117D, GLY120C, GLY120D, GLY228C, GLY228D, GLY233C, GLY233D, GLY234C, GLY234D, GLY237C, GLY237D, GLY240C, GLY240D, GLY243C, GLY243D, GLY252C, GLY252D, GLY253C, GLY253D, GLY258C, GLY258D, GLY259C, GLY259D, GLY260C, GLY260D, GLY264C, GLY264D, GLY303C, GLY303D, GLY48C, GLY48D, GLY53C, GLY53D, GLY54C, GLY54D, GLY96C, GLY96D, HIS14C, HIS14D, HIS189C, HIS189D, HIS257C, HIS257D, HIS3C, HIS3D, ILE102C, ILE102D, ILE138C, ILE138D, ILE224C, ILE224D, ILE232C, ILE232D, ILE246C, ILE246D, ILE247C, ILE247D, ILE302C, ILE302D, ILE310C, ILE310D, ILE56C, ILE56D, ILE95C, ILE95D, LEU121C, LEU121D, LEU185C, LEU185D, LEU241C, LEU241D, LEU4C, LEU4D, LEU51C, LEU51D, LEU92C, LEU92D, LYS165C, LYS165D, LYS221C, LYS221D, LYS245C, LYS245D, LYS265C, LYS265D, LYS269C, LYS269D, LYS2C, LYS2D, LYS46C, LYS46D, LYS97C, LYS97D, MET122C, MET122D, MET236C, MET236D, MET254C, MET254D, MET311C, MET311D, MET49C, MET49D, PHE123C, PHE123D, PHE170C, PHE170D, PHE222C, PHE222D, PHE223C, PHE223D, PHE230C, PHE230D, PHE262C, PHE262D, PHE315C, PHE315D, PHE5C, PHE5D, PRO100C, PRO100D, PRO137C, PRO137D, PRO15C, PRO15D, PRO226C, PRO226D, PRO235C, PRO235D, PRO307C, PRO307D, SER11C, SER11D, SER166C, SER166D, SER186C, SER186D, SER23C, SER23D, SER263C, SER263D, SER299C, SER299D, SER309C, SER309D, SER322C, SER322D, SER7C, SER7D, SER93C, SER93D, SER99C, SER99D, SER9C, SER9D, THR169C, THR169D, THR187C, THR187D, THR227C, THR227D, THR242C, THR242D, THR250C, THR308C, THR308D, THR326C, THR326D, THR43C, THR43D, THR47C, THR47D, THR6C, THR6D, TYR125C, TYR125D, TYR172C, TYR172D, TYR251C, TYR251D, TYR300C, TYR300D, TYR44C, TYR44D, VAL106C, VAL106D, VAL10C, VAL10D, VAL145C, VAL145D, VAL168C, VAL168D, VAL183C, VAL183D, VAL184C, VAL184D, VAL231C, VAL231D, VAL248C, VAL248D, VAL298C, VAL298D, VAL304C, VAL304D, VAL312C, VAL312D, VAL45C, VAL45D, VAL52C, VAL52D