1R20

crystal structure of the ligand-binding domains of the heterodimer ecr/usp bound to the synthetic agonist byi06830

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 118
  • Norm. En. per Res.: -2.8575
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-20.6769	-77.6085	-238.901	-337.1865	118	9	9	11134	9	39	36

Interface residues

• A-D: ALA415A, ALA416A, ALA423A, ALA479D, ALA484D, ARG347A, ARG385A, ARG392A, ARG404A, ARG413A, ARG420A, ARG425A, ARG425D, ARG449D, ARG463D, ARG470D, ARG482D, ARG498D, ASN376A, ASN467D, ASN506D, ASP378A, ASP400A, ASP419D, ASP448D, CYS398A, CYS426D, GLN343A, GLN386A, GLN462D, GLN503D, GLU288A, GLU351A, GLU378D, GLU389A, GLU393A, GLU401A, GLU410A, GLU411A, GLU418D, GLU433A, GLU459D, GLU496D, GLY381A, GLY412A, GLY451D, GLY488D, GLY492D, GLY501D, HIS422D, ILE372A, ILE373A, ILE427A, ILE443D, ILE486D, ILE490D, ILE493D, ILE497D, LEU359A, LEU382A, LEU391A, LEU397A, LEU399A, LEU417A, LEU418A, LEU419A, LEU420D, LEU421A, LEU424A, LEU429A, LEU466D, LEU469D, LEU474D, LEU491D, LEU494D, LEU500D, LYS355A, LYS380A, LYS394A, LYS430A, LYS489D, MET395A, MET427D, MET430D, MET502D, PHE396A, PHE414A, PHE423D, PHE432A, PHE436A, PHE446D, PHE487D, PRO288D, PRO377A, PRO422A, PRO450D, PRO455D, PRO481D, SER350A, SER408A, SER426A, SER428A, SER429D, SER447D, SER456D, SER480D, SER483D, SER505D, THR358A, THR495D, THR499D, TYR415D, TYR428D, VAL379A, VAL390A, VAL444D, VAL471D, VAL485D