1QOX

beta-glucosidase from bacillus circulans sp. alkalophilus

• Total interactions analyzed: 120
• Total true interactions: 34
• Strongest Interaction:
  • Chains: A-O
  • Int. Res.: 12
  • Norm. En. per Res.: -5.3871
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-6.5072	-53.011	-78.8932	-138.4114	55	10	1	3047	4	18	16
A-C	0.0	0.0	-0.5581	-0.5581	2	0	0	97	0	0	0
A-D	-4.6351	-51.4231	-87.6206	-143.6788	55	8	1	3226	4	19	16
A-E	-46.0789	-84.2415	-306.454	-436.7744	115	22	0	11303	6	44	38
A-O	-25.4336	-39.2078	-0.0037	-64.6451	12	0	0	4	0	4	2
B-C	-6.7651	-55.0841	-94.291	-156.1402	56	16	1	3501	4	19	16
B-D	0.0	0.0	-0.2845	-0.2845	2	0	0	71	0	0	0
B-H	-45.2714	-86.442	-295.199	-426.9125	115	17	0	11054	6	44	37
B-N	-26.0272	-56.5285	-55.5932	-138.1489	40	5	0	1971	6	27	24
C-D	-7.1233	-54.8949	-83.2789	-145.2971	55	15	1	3165	4	18	16
C-G	-43.3123	-83.251	-309.908	-436.4712	117	22	0	11299	6	43	37
C-M	-43.4813	-49.4073	-64.5184	-157.4069	42	8	0	2346	8	28	24
D-F	-42.1277	-90.2584	-309.786	-442.1721	115	18	0	11261	7	43	39
D-P	-23.9192	-39.8732			8
E-F	-7.1116	-54.599	-84.878	-146.5885	56	9	1	3250	4	18	16
E-G	0.0	0.0	-0.4296	-0.4296	2	0	0	88	0	0	0
E-H	-5.0712	-51.3505	-75.485	-131.9067	53	8	1	3103	4	19	16
F-G	-6.8224	-54.5678	-88.359	-149.7493	56	12	1	3401	4	19	16
F-H	0.0	0.0	-0.3358	-0.3358	2	0	0	76	0	0	0
G-H	-6.6558	-51.3064	-78.94	-136.9022	54	7	1	3050	4	18	16
I-J	-4.5167	-47.2668	-71.5124	-123.2959	52	8	1	3006	4	19	16
I-K	0.0	0.0	-0.256	-0.256	2	0	0	67	0	0	0
I-L	0.0	-44.5914	-63.9208	-108.5122	50	8	1	2801	3	17	16
I-M	-44.0115	-87.1009	-312.041	-443.1534	114	20	0	11303	6	43	38
J-K	-4.6291	-49.2968	-76.3412	-130.267	53	17	1	3238	4	19	16
J-L	0.0	0.0	-0.2901	-0.2901	2	0	0	68	0	0	0
J-P	-43.8002	-78.2487			22
K-L	-5.7352	-47.2022	-65.5097	-118.4471	50	13	1	3117	4	18	16
K-O	-47.1776	-92.7004	-20.6452	-160.5232	34	2	0	849	0	2	2
L-N	-41.4965	-78.7459	-278.44	-398.6823	115	16	0	10811	5	42	37
M-N	-6.358	-56.9732	-78.1854	-141.5166	56	14	1	3425	4	19	16
M-P	-3.9152	-46.7273			9
N-O	-4.494	-46.6836	-5.0118	-56.1893	20	3	0	356	0	0	3
O-P	-6.6198	-55.5242			9

Interface residues

• A-B: ALA39A, ARG369B, ARG417A, ARG445B, ASN47A, ASN50A, ASN52A, ASP367B, ASP424A, ASP426A, ASP434B, ASP449B, ASP49A, GLY368B, GLY43A, GLY441B, GLY446B, GLY48A, HIS371B, HIS40A, HIS422A, HIS4B, ILE3B, LEU364A, LEU366A, LEU366B, LEU428A, LEU448B, LEU450B, LYS433B, LYS440B, LYS44A, LYS46A, MET5B, PHE38A, PHE436B, PHE6B, PRO42A, PRO432B, SER2B, SER365A, SER365B, SER444B, THR41A, THR427A, THR431B, TRP438B, TRP447B, TYR25A, TYR425A, TYR437B, VAL429A, VAL442B, VAL45A, VAL53A
• A-C: LEU366A, LEU366C
• A-D: ALA39D, ARG369A, ARG417D, ARG445A, ASN47D, ASN50D, ASN52D, ASP367A, ASP424D, ASP426D, ASP434A, ASP449A, ASP49D, ASP70A, GLY368A, GLY43D, GLY441A, GLY446A, GLY48D, HIS371A, HIS40D, HIS422D, HIS4A, ILE3A, LEU364D, LEU366A, LEU366D, LEU428D, LEU448A, LEU450A, LYS433A, LYS440A, LYS44D, LYS46D, MET5A, PHE38D, PHE436A, PHE6A, PRO42D, PRO432A, SER365A, SER365D, SER444A, THR41D, THR427D, THR431A, TRP438A, TRP447A, TYR25D, TYR425D, TYR437A, VAL429D, VAL442A, VAL45D, VAL53D
• A-E: ALA226E, ALA316A, ALA316E, ALA321A, ALA321E, ALA332A, ALA332E, ALA343A, ALA343E, ALA380A, ALA380E, ALA386A, ALA386E, ALA389A, ALA389E, ARG230A, ARG230E, ARG231A, ARG231E, ARG302A, ARG302E, ARG340A, ARG340E, ARG388A, ARG388E, ASN301A, ASN301E, ASP235A, ASP235E, ASP337A, ASP337E, ASP344A, ASP344E, ASP377A, ASP377E, ASP392A, ASP392E, ASP449A, ASP449E, CYS239E, GLN385A, GLN385E, GLU315A, GLU315E, GLU329A, GLU329E, GLU333A, GLU333E, GLU391A, GLU391E, GLY320A, GLY320E, GLY393A, GLY393E, HIS382A, HIS382E, HIS4A, HIS4E, ILE317A, ILE317E, ILE330A, ILE330E, ILE384A, ILE384E, ILE390A, ILE390E, ILE394A, ILE394E, ILE3A, ILE3E, LEU339A, LEU339E, LEU383A, LEU448A, LEU448E, LEU450A, LEU450E, LYS323A, LYS323E, LYS345A, LYS345E, MET300A, MET300E, MET319A, MET319E, MET381A, MET381E, MET5A, MET5E, PRO228A, PRO228E, PRO322A, PRO322E, SER299A, SER299E, SER2A, SER2E, SER318A, SER318E, SER387A, SER387E, THR232A, THR232E, TYR229A, TYR229E, TYR331A, TYR331E, TYR336A, TYR336E, TYR341A, TYR341E, TYR378A, TYR378E, VAL227A, VAL227E
• A-O: ARG95A, ARG95O, ASP99A, ASP99O, GLU153A, GLU153O, GLU92O, GLY156A, HIS102A, HIS102O, LYS152A, VAL85O
• B-C: ALA39B, ARG369C, ARG417B, ARG445C, ASN47B, ASN50B, ASN52B, ASP367C, ASP424B, ASP426B, ASP434C, ASP449C, ASP49B, ASP70C, GLY368C, GLY43B, GLY441C, GLY446C, GLY48B, HIS371C, HIS40B, HIS422B, HIS4C, ILE3C, LEU364B, LEU366B, LEU366C, LEU428B, LEU448C, LEU450C, LYS433C, LYS440C, LYS44B, LYS46B, MET5C, PHE38B, PHE436C, PHE6C, PRO42B, PRO432C, SER2C, SER365B, SER365C, SER444C, THR41B, THR427B, THR431C, TRP438C, TRP447C, TYR25B, TYR425B, TYR437C, VAL429B, VAL442C, VAL45B, VAL53B
• B-D: LEU366B, LEU366D
• B-H: ALA308H, ALA316B, ALA316H, ALA321B, ALA321H, ALA332B, ALA332H, ALA343B, ALA343H, ALA380B, ALA380H, ALA386B, ALA386H, ALA389B, ALA389H, ARG230B, ARG230H, ARG231B, ARG231H, ARG302B, ARG302H, ARG340B, ARG340H, ARG388B, ARG388H, ASN301B, ASN301H, ASP235B, ASP235H, ASP337B, ASP337H, ASP344B, ASP344H, ASP377B, ASP377H, ASP392B, ASP392H, ASP449B, ASP449H, CYS239H, GLN385B, GLN385H, GLU315B, GLU315H, GLU329B, GLU329H, GLU333B, GLU333H, GLU391B, GLU391H, GLY320B, GLY320H, GLY393B, GLY393H, HIS382B, HIS382H, HIS4B, HIS4H, ILE317B, ILE317H, ILE330B, ILE330H, ILE384B, ILE384H, ILE390B, ILE390H, ILE394B, ILE394H, ILE3B, ILE3H, LEU339B, LEU339H, LEU383B, LEU448B, LEU448H, LEU450B, LEU450H, LYS323B, LYS323H, LYS345B, LYS345H, MET300B, MET300H, MET319B, MET319H, MET381B, MET381H, MET5B, MET5H, PRO228B, PRO228H, PRO322B, PRO322H, SER299B, SER299H, SER2B, SER2H, SER318B, SER318H, SER387B, SER387H, THR232B, THR232H, TYR229B, TYR229H, TYR331B, TYR331H, TYR336B, TYR336H, TYR341B, TYR341H, TYR378B, TYR378H, VAL227B, VAL227H
• B-N: ALA96B, ALA96N, ARG103B, ARG103N, ARG95B, ARG95N, ASN94B, ASN94N, ASP106B, ASP106N, ASP99B, ASP99N, GLU153B, GLU153N, GLU92B, GLU92N, GLY156B, GLY156N, GLY97B, GLY97N, HIS102B, HIS102N, LEU149B, LEU149N, LEU154B, LEU154N, LEU98B, LEU98N, LYS152B, LYS152N, LYS157B, LYS157N, TYR100B, TYR100N, TYR101B, TYR101N, VAL85B, VAL85N, VAL93B, VAL93N
• C-D: ALA39C, ARG369D, ARG417C, ARG445D, ASN47C, ASN50C, ASN52C, ASP367D, ASP424C, ASP426C, ASP434D, ASP449D, ASP49C, ASP70D, GLY368D, GLY43C, GLY441D, GLY446D, GLY48C, HIS371D, HIS40C, HIS422C, HIS4D, ILE3D, LEU364C, LEU366C, LEU366D, LEU428C, LEU448D, LEU450D, LYS433D, LYS440D, LYS44C, LYS46C, MET5D, PHE38C, PHE436D, PHE6D, PRO42C, PRO432D, SER365C, SER365D, SER444D, THR41C, THR427C, THR431D, TRP438D, TRP447D, TYR25C, TYR425C, TYR437D, VAL429C, VAL442D, VAL45C, VAL53C
• C-G: ALA226C, ALA226G, ALA308G, ALA316C, ALA316G, ALA321C, ALA321G, ALA332C, ALA332G, ALA343C, ALA343G, ALA380C, ALA380G, ALA386C, ALA386G, ALA389C, ALA389G, ARG230C, ARG230G, ARG231C, ARG231G, ARG302C, ARG302G, ARG340C, ARG340G, ARG388C, ARG388G, ASN301C, ASN301G, ASP235C, ASP235G, ASP337C, ASP337G, ASP344C, ASP344G, ASP377C, ASP377G, ASP392C, ASP392G, ASP449C, ASP449G, CYS239G, GLN385C, GLN385G, GLU315C, GLU315G, GLU329C, GLU329G, GLU333C, GLU333G, GLU391C, GLU391G, GLY320C, GLY320G, GLY393C, GLY393G, HIS382C, HIS382G, HIS4C, HIS4G, ILE317C, ILE317G, ILE330C, ILE330G, ILE384C, ILE384G, ILE390C, ILE390G, ILE394C, ILE394G, ILE3C, ILE3G, LEU339C, LEU339G, LEU383C, LEU448C, LEU448G, LEU450C, LEU450G, LYS323C, LYS323G, LYS345C, LYS345G, MET300C, MET300G, MET319C, MET319G, MET381C, MET381G, MET5C, MET5G, PRO228C, PRO228G, PRO322C, PRO322G, SER299C, SER299G, SER2C, SER2G, SER318C, SER318G, SER387C, SER387G, THR232C, THR232G, TYR229C, TYR229G, TYR331C, TYR331G, TYR336C, TYR336G, TYR341C, TYR341G, TYR378C, TYR378G, VAL227C, VAL227G
• C-M: ALA96C, ALA96M, ARG103C, ARG103M, ARG95C, ARG95M, ASN94C, ASN94M, ASP106C, ASP106M, ASP99C, ASP99M, GLU153C, GLU153M, GLU92C, GLU92M, GLY156C, GLY156M, GLY97C, GLY97M, HIS102C, HIS102M, LEU149C, LEU149M, LEU154C, LEU154M, LEU98C, LEU98M, LYS152C, LYS152M, LYS157C, LYS157M, MET150C, MET150M, TYR100C, TYR100M, TYR101C, TYR101M, VAL85C, VAL85M, VAL93C, VAL93M
• D-F: ALA226F, ALA308F, ALA316D, ALA316F, ALA321D, ALA321F, ALA332D, ALA332F, ALA343D, ALA343F, ALA380D, ALA380F, ALA386D, ALA389D, ALA389F, ARG230D, ARG230F, ARG231D, ARG231F, ARG302D, ARG302F, ARG340D, ARG340F, ARG388D, ARG388F, ASN301D, ASN301F, ASP235D, ASP235F, ASP337D, ASP337F, ASP344D, ASP344F, ASP377D, ASP377F, ASP392D, ASP392F, ASP449D, ASP449F, CYS239F, GLN385D, GLN385F, GLU315D, GLU315F, GLU329D, GLU329F, GLU333D, GLU333F, GLU391D, GLU391F, GLY320D, GLY320F, GLY393D, GLY393F, HIS382D, HIS382F, HIS4D, HIS4F, ILE317D, ILE317F, ILE330D, ILE330F, ILE384D, ILE384F, ILE390D, ILE390F, ILE394D, ILE394F, ILE3D, ILE3F, LEU339D, LEU339F, LEU383D, LEU448D, LEU448F, LEU450D, LEU450F, LYS323D, LYS323F, LYS345D, LYS345F, MET300D, MET300F, MET319D, MET319F, MET381D, MET381F, MET5D, MET5F, PRO228D, PRO228F, PRO322D, PRO322F, SER299D, SER299F, SER2D, SER2F, SER318D, SER318F, SER387D, SER387F, THR232D, THR232F, TYR229D, TYR229F, TYR331D, TYR331F, TYR336D, TYR336F, TYR341D, TYR341F, TYR378D, TYR378F, VAL227D, VAL227F
• D-P: ARG95D, ARG95P, ASP99D, ASP99P, GLU153D, GLU153P, HIS102D, HIS102P
• E-F: ALA39E, ARG369F, ARG417E, ARG445F, ASN47E, ASN50E, ASN52E, ASP367F, ASP424E, ASP426E, ASP434F, ASP449F, ASP49E, ASP70F, GLY368F, GLY43E, GLY441F, GLY446F, GLY48E, HIS371F, HIS40E, HIS422E, HIS4F, ILE3F, LEU364E, LEU366E, LEU366F, LEU428E, LEU448F, LEU450F, LYS433F, LYS440F, LYS44E, LYS46E, MET5F, PHE38E, PHE436F, PHE6F, PRO42E, PRO432F, SER2F, SER365E, SER365F, SER444F, THR41E, THR427E, THR431F, TRP438F, TRP447F, TYR25E, TYR425E, TYR437F, VAL429E, VAL442F, VAL45E, VAL53E
• E-G: LEU366E, LEU366G
• E-H: ALA39H, ARG369E, ARG417H, ARG445E, ASN47H, ASN50H, ASN52H, ASP367E, ASP424H, ASP426H, ASP434E, ASP449E, ASP49H, GLY368E, GLY43H, GLY441E, GLY446E, GLY48H, HIS371E, HIS40H, HIS422H, HIS4E, ILE3E, LEU364H, LEU366E, LEU366H, LEU428H, LEU448E, LEU450E, LYS433E, LYS440E, LYS44H, LYS46H, MET5E, PHE38H, PHE436E, PRO42H, PRO432E, SER2E, SER365E, SER365H, SER444E, THR41H, THR427H, THR431E, TRP438E, TRP447E, TYR25H, TYR425H, TYR437E, VAL429H, VAL45H, VAL53H
• F-G: ALA39F, ARG369G, ARG417F, ARG445G, ASN47F, ASN50F, ASN52F, ASP367G, ASP424F, ASP426F, ASP434G, ASP449G, ASP49F, ASP70G, GLY368G, GLY43F, GLY441G, GLY446G, GLY48F, HIS371G, HIS40F, HIS422F, HIS4G, ILE3G, LEU364F, LEU366F, LEU366G, LEU428F, LEU448G, LEU450G, LYS433G, LYS440G, LYS44F, LYS46F, MET5G, PHE38F, PHE436G, PHE6G, PRO42F, PRO432G, SER2G, SER365F, SER365G, SER444G, THR41F, THR427F, THR431G, TRP438G, TRP447G, TYR25F, TYR425F, TYR437G, VAL429F, VAL442G, VAL45F, VAL53F
• F-H: LEU366F, LEU366H
• G-H: ALA39G, ARG369H, ARG417G, ARG445H, ASN47G, ASN50G, ASN52G, ASP367H, ASP424G, ASP426G, ASP434H, ASP449H, ASP49G, GLY368H, GLY43G, GLY441H, GLY446H, GLY48G, HIS371H, HIS40G, HIS422G, HIS4H, ILE3H, LEU364G, LEU366G, LEU366H, LEU428G, LEU448H, LEU450H, LYS433H, LYS440H, LYS44G, LYS46G, MET5H, PHE38G, PHE436H, PHE6H, PRO42G, PRO432H, SER365G, SER365H, SER444H, THR41G, THR427G, THR431H, TRP438H, TRP447H, TYR25G, TYR425G, TYR437H, VAL429G, VAL442H, VAL45G, VAL53G
• I-J: ALA39I, ARG369J, ARG417I, ARG445J, ASN47I, ASN50I, ASN52I, ASP367J, ASP424I, ASP426I, ASP434J, ASP449J, ASP49I, ASP70J, GLY368J, GLY43I, GLY441J, GLY48I, HIS371J, HIS40I, HIS422I, HIS4J, ILE3J, LEU364I, LEU366I, LEU366J, LEU428I, LEU448J, LEU450J, LYS433J, LYS440J, LYS44I, LYS46I, MET5J, PHE38I, PHE436J, PRO42I, PRO432J, SER2J, SER365I, SER365J, SER444J, THR41I, THR427I, TRP438J, TRP447J, TYR25I, TYR425I, TYR437J, VAL429I, VAL45I, VAL53I
• I-K: LEU366I, LEU366K
• I-L: ALA39L, ARG369I, ARG445I, ASN47L, ASN50L, ASN52L, ASP367I, ASP424L, ASP426L, ASP434I, ASP449I, ASP49L, GLY368I, GLY43L, GLY441I, GLY446I, GLY48L, HIS371I, HIS40L, HIS422L, HIS4I, ILE3I, LEU364L, LEU366I, LEU366L, LEU428L, LEU448I, LEU450I, LYS433I, LYS440I, LYS44L, LYS46L, MET5I, PHE38L, PHE436I, PRO42L, PRO432I, SER2I, SER365I, SER365L, SER444I, THR41L, THR427L, TRP438I, TRP447I, TYR425L, TYR437I, VAL429L, VAL45L, VAL53L
• I-M: ALA226I, ALA308M, ALA316I, ALA316M, ALA321I, ALA321M, ALA332I, ALA332M, ALA343I, ALA343M, ALA380I, ALA380M, ALA386I, ALA386M, ALA389I, ALA389M, ARG230I, ARG230M, ARG231I, ARG231M, ARG302I, ARG302M, ARG340I, ARG340M, ARG388I, ARG388M, ASN301I, ASN301M, ASP235I, ASP235M, ASP337I, ASP337M, ASP344I, ASP344M, ASP377I, ASP377M, ASP392I, ASP392M, ASP449I, ASP449M, GLN385I, GLN385M, GLU315I, GLU315M, GLU329I, GLU329M, GLU333I, GLU333M, GLU391I, GLU391M, GLY320I, GLY320M, GLY393I, GLY393M, HIS382I, HIS382M, HIS4I, HIS4M, ILE317I, ILE317M, ILE330I, ILE330M, ILE384I, ILE384M, ILE390I, ILE390M, ILE394I, ILE394M, ILE3I, ILE3M, LEU339I, LEU339M, LEU448I, LEU448M, LEU450I, LEU450M, LYS323I, LYS323M, LYS345I, LYS345M, MET300I, MET300M, MET319I, MET319M, MET381I, MET381M, MET5I, MET5M, PRO228I, PRO228M, PRO322I, PRO322M, SER299I, SER299M, SER2I, SER2M, SER318I, SER318M, SER387I, SER387M, THR232I, THR232M, TYR229I, TYR229M, TYR331I, TYR331M, TYR336I, TYR336M, TYR341I, TYR341M, TYR378I, TYR378M, VAL227I, VAL227M
• J-K: ALA39J, ARG369K, ARG445K, ASN47J, ASN50J, ASN52J, ASP367K, ASP424J, ASP426J, ASP434K, ASP449K, ASP49J, GLY368K, GLY43J, GLY441K, GLY446K, GLY48J, HIS371K, HIS40J, HIS422J, HIS4K, ILE3K, LEU364J, LEU366J, LEU366K, LEU428J, LEU448K, LEU450K, LYS433K, LYS440K, LYS44J, LYS46J, MET5K, PHE38J, PHE436K, PHE6K, PRO42J, PRO432K, SER2K, SER365J, SER365K, SER444K, THR41J, THR427J, TRP438K, TRP447K, TYR25J, TYR425J, TYR437K, VAL429J, VAL442K, VAL45J, VAL53J
• J-L: LEU366J, LEU366L
• J-P: ARG230J, ARG230P, ARG231J, ARG231P, ARG302J, ARG302P, ARG340J, ARG340P, ARG388J, ARG388P, ASP235J, ASP235P, ASP344J, ASP344P, ASP392J, ASP392P, GLU333J, GLU333P, GLU391J, GLU391P, TYR229J, TYR229P
• K-L: ALA39K, ARG369L, ARG445L, ASN47K, ASN50K, ASN52K, ASP367L, ASP424K, ASP426K, ASP434L, ASP449L, ASP49K, GLY368L, GLY43K, GLY441L, GLY48K, HIS371L, HIS40K, HIS422K, HIS4L, ILE3L, LEU364K, LEU366K, LEU366L, LEU428K, LEU448L, LEU450L, LYS433L, LYS440L, LYS44K, LYS46K, MET5L, PHE38K, PHE436L, PRO42K, PRO432L, SER2L, SER365K, SER365L, SER444L, THR41K, THR427K, TRP438L, TRP447L, TYR25K, TYR425K, TYR437L, VAL429K, VAL45K, VAL53K
• K-O: ALA316K, ARG230K, ARG230O, ARG231K, ARG231O, ARG302K, ARG302O, ARG340K, ARG340O, ARG388K, ARG388O, ASP235K, ASP235O, ASP344K, ASP344O, ASP392K, ASP392O, GLU315K, GLU333K, GLU333O, GLU391K, GLU391O, GLY320K, HIS4O, ILE317K, ILE3O, LYS323K, MET300K, MET319K, MET5O, SER2O, SER318K, TYR229K, TYR229O
• L-N: ALA308N, ALA316L, ALA316N, ALA321L, ALA321N, ALA332L, ALA332N, ALA343L, ALA343N, ALA380L, ALA380N, ALA386L, ALA386N, ALA389L, ALA389N, ARG230L, ARG230N, ARG231L, ARG231N, ARG302L, ARG302N, ARG340L, ARG340N, ARG388L, ARG388N, ASN301L, ASN301N, ASP235L, ASP235N, ASP337L, ASP337N, ASP344L, ASP344N, ASP377L, ASP377N, ASP392L, ASP392N, ASP449L, ASP449N, CYS239N, GLN385L, GLN385N, GLU315L, GLU315N, GLU329L, GLU329N, GLU333L, GLU333N, GLU391L, GLU391N, GLY320L, GLY320N, GLY393L, GLY393N, HIS382L, HIS382N, HIS4L, HIS4N, ILE317L, ILE317N, ILE330L, ILE330N, ILE384L, ILE384N, ILE390L, ILE390N, ILE394L, ILE394N, ILE3L, ILE3N, LEU339L, LEU339N, LEU383L, LEU448L, LEU448N, LEU450L, LEU450N, LYS323L, LYS323N, LYS345L, LYS345N, MET300L, MET300N, MET319L, MET319N, MET381L, MET381N, MET5L, MET5N, PRO228L, PRO228N, PRO322L, PRO322N, SER299L, SER299N, SER2L, SER2N, SER318L, SER318N, SER387L, SER387N, THR232L, THR232N, TYR229L, TYR229N, TYR331L, TYR331N, TYR336L, TYR336N, TYR341L, TYR341N, TYR378L, TYR378N, VAL227L, VAL227N
• M-N: ALA39M, ARG369N, ARG417M, ARG445N, ASN47M, ASN50M, ASN52M, ASP367N, ASP424M, ASP426M, ASP434N, ASP449N, ASP49M, ASP70N, GLY368N, GLY43M, GLY441N, GLY446N, GLY48M, HIS371N, HIS40M, HIS422M, HIS4N, ILE3N, LEU364M, LEU366M, LEU366N, LEU428M, LEU448N, LEU450N, LYS433N, LYS440N, LYS44M, LYS46M, MET5N, PHE38M, PHE436N, PHE6N, PRO42M, PRO432N, SER2N, SER365M, SER365N, SER444N, THR41M, THR427M, THR431N, TRP438N, TRP447N, TYR25M, TYR425M, TYR437N, VAL429M, VAL442N, VAL45M, VAL53M
• M-P: ARG369M, ARG445M, ASP424P, ASP426P, ASP434M, ASP449M, ASP49P, LYS440M, LYS46P
• N-O: ARG369O, ARG445O, ASP424N, ASP426N, ASP434O, ASP449O, ASP49N, GLY43N, GLY48N, HIS40N, HIS4O, ILE3O, LYS440O, LYS44N, LYS46N, MET5O, PRO42N, SER2O, THR41N, VAL45N
• O-P: ARG369P, ARG445P, ASP424O, ASP426O, ASP434P, ASP449P, ASP49O, LYS440P, LYS46O