1QK4

toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase imp complex

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 40
  • Norm. En. per Res.: -4.5393
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-70.7069	-147.9852	-315.499	-534.1911	139	18	3	13955	9	62	63
A-C	-23.0441	-37.1449	-227.851	-288.04	90	8	3	8815	3	36	35
A-D	-11.3054	-31.5493	-101.795	-144.6497	42	6	3	3754	4	16	18
B-C	-43.1604	-31.9024	-106.51	-181.5728	40	5	3	3626	4	15	18
B-D	-23.569	-31.7284	-216.329	-271.6265	89	6	3	8575	3	35	35
C-D	-57.313	-79.2215	-291.081	-427.6155	134	11	3	12614	6	60	55

Interface residues

• A-B: ALA93A, ALA93B, ARG101A, ARG101B, ARG114A, ARG114B, ARG212A, ARG212B, ARG82A, ARG82B, ASN208A, ASN208B, ASN86A, ASN86B, ASP132A, ASP132B, ASP133A, ASP133B, ASP206A, ASP206B, ASP213A, ASP213B, ASP215A, ASP215B, ASP90A, ASP90B, CYS204A, CYS204B, CYS38A, CYS38B, CYS76A, CYS76B, GLN96A, GLN96B, GLU102A, GLU102B, GLU110A, GLU110B, GLU209A, GLU209B, GLY100A, GLY100B, GLY80A, GLY80B, GLY83A, GLY83B, HIS111A, HIS111B, HIS216A, HIS216B, HIS37A, HIS37B, HIS73A, HIS73B, ILE136A, ILE136B, ILE74A, ILE89A, ILE89B, LEU115A, LEU130A, LEU130B, LEU33A, LEU33B, LEU78A, LEU78B, LEU87A, LEU87B, LEU92A, LEU92B, LYS116A, LYS116B, LYS227A, LYS227B, LYS39A, LYS39B, LYS53A, LYS53B, LYS79A, LYS79B, LYS97A, LYS97B, MET210A, MET210B, PHE108A, PHE108B, PHE109A, PHE109B, PHE137A, PHE137B, PHE207A, PHE211A, PHE211B, PHE214A, PHE214B, PHE228A, PHE228B, PHE32A, PHE32B, PHE68B, PHE85A, PHE85B, PRO106A, PRO106B, PRO107A, PRO107B, PRO35A, PRO35B, PRO36A, PRO36B, PRO40A, PRO40B, SER103A, SER103B, SER104A, SER104B, SER131A, SER131B, SER81B, SER99A, SER99B, THR128A, THR128B, THR94A, THR94B, TYR112A, TYR112B, TYR41A, TYR41B, TYR98A, TYR98B, VAL105A, VAL105B, VAL113A, VAL113B, VAL129A, VAL129B, VAL34A, VAL34B
• A-C: ALA29A, ALA29C, ALA60A, ALA60C, ARG55A, ARG55C, ARG65A, ARG65C, ASN28A, ASN28C, ASP215A, ASP215C, ASP30A, ASP30C, ASP31A, ASP31C, ASP54A, ASP54C, ASP62A, ASP62C, GLU17A, GLU17C, GLU57A, GLU57C, GLY192A, GLY192C, GLY49A, GLY49C, GLY50A, GLY50C, HIS216A, HIS216C, ILE16A, ILE16C, ILE21A, ILE21C, ILE45A, ILE45C, ILE95A, ILE95C, LEU33A, LEU33C, LEU46A, LEU46C, LEU47A, LEU47C, LEU51A, LEU51C, LEU59A, LEU59C, LYS39A, LYS39C, LYS53A, LYS53C, LYS58A, LYS58C, MET19A, MET19C, PHE193A, PHE193C, PHE26A, PHE26C, PHE32A, PHE32C, PRO18A, PRO18C, PRO22A, PRO22C, PRO35A, PRO35C, PRO36A, PRO36C, PRO48A, PRO48C, THR25A, THR25C, TYR20A, TYR20C, TYR27A, TYR27C, TYR61A, TYR61C, TYR91A, TYR91C, VAL34A, VAL34C, VAL52A, VAL52C, VAL56A, VAL56C
• A-D: ALA60A, ALA60D, ALA93A, ALA93D, ARG101A, ARG101D, ARG65A, ARG65D, ASP54A, ASP54D, ASP90A, ASP90D, GLN96A, GLN96D, GLU102A, GLU102D, GLU57A, GLU57D, GLY100A, GLY100D, HIS64A, HIS64D, ILE95A, ILE95D, LEU92A, LEU92D, LYS58A, LYS58D, LYS97A, LYS97D, PHE68A, SER99A, SER99D, THR94A, THR94D, TYR61A, TYR61D, TYR91A, TYR91D, TYR98A, TYR98D, VAL56A
• B-C: ALA60B, ALA60C, ALA93B, ALA93C, ARG101B, ARG101C, ARG65B, ARG65C, ASP54B, ASP54C, ASP90B, ASP90C, GLN96B, GLN96C, GLU102B, GLU102C, GLU57B, GLU57C, GLY100B, GLY100C, HIS64B, HIS64C, ILE95B, ILE95C, LEU92C, LYS58B, LYS58C, LYS97B, LYS97C, PHE68C, SER99B, SER99C, THR94B, THR94C, TYR61B, TYR61C, TYR91B, TYR91C, TYR98B, TYR98C
• B-D: ALA29B, ALA29D, ALA60B, ALA60D, ARG55B, ARG55D, ARG65B, ARG65D, ASN28B, ASN28D, ASP215B, ASP215D, ASP30B, ASP30D, ASP31B, ASP31D, ASP54B, ASP54D, ASP62B, ASP62D, GLU17B, GLU17D, GLU57B, GLU57D, GLY192B, GLY192D, GLY49B, GLY49D, GLY50B, GLY50D, HIS216B, HIS216D, ILE16B, ILE16D, ILE21B, ILE21D, ILE45B, ILE45D, ILE95B, ILE95D, LEU33B, LEU33D, LEU46B, LEU46D, LEU47B, LEU47D, LEU51B, LEU51D, LEU59B, LEU59D, LYS39B, LYS39D, LYS53B, LYS53D, LYS58B, LYS58D, MET19B, MET19D, PHE193B, PHE193D, PHE32B, PHE32D, PRO18B, PRO18D, PRO22B, PRO22D, PRO35B, PRO35D, PRO36B, PRO36D, PRO48B, PRO48D, THR25B, THR25D, TYR20B, TYR20D, TYR27B, TYR27D, TYR61B, TYR61D, TYR91B, TYR91D, VAL217B, VAL34B, VAL34D, VAL52B, VAL52D, VAL56B, VAL56D
• C-D: ALA93C, ALA93D, ARG101C, ARG101D, ARG114C, ARG114D, ARG212C, ARG212D, ARG82C, ARG82D, ASN208C, ASN208D, ASN86C, ASN86D, ASP132C, ASP132D, ASP133C, ASP206C, ASP206D, ASP213C, ASP213D, ASP215C, ASP215D, ASP90C, ASP90D, CYS204C, CYS204D, CYS38C, CYS38D, CYS76C, CYS76D, GLN96C, GLN96D, GLU102C, GLU102D, GLU110C, GLU110D, GLU209C, GLU209D, GLU71C, GLY100C, GLY100D, GLY80C, GLY80D, GLY83C, GLY83D, HIS111C, HIS111D, HIS216C, HIS216D, HIS37C, HIS37D, HIS73C, HIS73D, ILE136C, ILE136D, ILE74C, ILE74D, ILE75D, ILE89C, ILE89D, LEU115C, LEU115D, LEU130D, LEU33C, LEU33D, LEU78C, LEU78D, LEU87C, LEU92C, LEU92D, LYS116C, LYS116D, LYS227C, LYS227D, LYS39C, LYS39D, LYS53C, LYS53D, LYS79C, LYS79D, LYS97C, LYS97D, MET210C, MET210D, PHE108C, PHE108D, PHE109C, PHE109D, PHE137C, PHE137D, PHE207C, PHE207D, PHE211C, PHE211D, PHE214C, PHE214D, PHE228C, PHE228D, PHE32C, PHE32D, PHE68D, PHE85C, PHE85D, PRO106C, PRO106D, PRO107C, PRO107D, PRO35C, PRO35D, PRO36C, PRO36D, PRO40C, PRO40D, SER103C, SER103D, SER104C, SER104D, SER99C, SER99D, THR94C, THR94D, TYR112C, TYR112D, TYR41C, TYR41D, TYR98C, TYR98D, VAL105C, VAL105D, VAL113C, VAL113D, VAL34C, VAL34D