1QFW

ternary complex of human chorionic gonadotropin with fv anti alpha subunit and fv anti beta subunit

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 163
  • Norm. En. per Res.: -4.2784
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-132.8602	-20.1375	-544.383	-697.3807	163	47	11	22529	1	29	28
A-L	0.0	0.0	-57.5134	-57.5134	31	0	0	2065	0	0	2
A-H	-7.7362	-26.8247	-81.5625	-116.1234	40	17	0	4183	1	2	1
A-M	-6.284	-10.1064	-19.4311	-35.8214	22	0	0	893	1	8	2
B-L	0.0	-8.9358	-21.2361	-30.1719	18	1	0	1203	0	2	0
B-H	0.0	0.0	-0.0038	-0.0038	2	0	0	4	0	0	0
B-M	0.0	-0.4536	-94.9528	-95.4064	46	5	1	3703	0	9	9
B-I	-18.5407	-33.7804	-87.3206	-139.6417	43	14	0	3577	3	2	2
L-H	0.0	11.2395	-181.15	-169.9105	77	23	3	7913	0	7	10
M-I	-11.4082	2.5772	-217.498	-226.329	95	6	5	8962	0	16	14

Interface residues

• A-B: ALA14B, ALA17B, ALA35B, ALA36A, ALA51B, ALA62A, ALA83B, ALA85B, ALA91B, ARG10B, ARG35A, ARG42A, ARG43B, ARG67A, ARG6B, ARG8B, ARG94B, ARG95B, ASN13B, ASN15A, ASN52A, ASN58B, ASN66A, ASN78A, ASP105B, ASP111B, ASP6A, ASP6A5, ASP99B, CB4.1684646.46604, CB5.41972-28.13542, CB9.95949-5.56934, CYS100B, CYS10A, CYS110B, CYS23B, CYS26B, CYS28A, CYS31A, CYS32A, CYS34B, CYS38B, CYS57B, CYS59A, CYS60A, CYS7A, CYS82A, CYS84A, CYS87A, CYS88B, CYS90B, CYS93B, CYS9B, GLN13A, GLN27A, GLN46B, GLN50A, GLN54B, GLN89B, GLU19B, GLU21B, GLU3B, GLU56A, GLU77A, GLU9A, GLY101B, GLY102B, GLY22B, GLY30A, GLY36B, GLY47B, GLY72A, GLY73A, HIS106B, HIS79A, HIS90A, ILE12B, ILE25A, ILE33B, LEU108B, LEU12A, LEU16B, LEU26A, LEU41A, LEU45B, LEU49B, LEU52B, LEU5B, LEU92B, LYS104B, LYS20B, LYS2B, LYS44A, LYS45A, LYS51A, LYS63A, LYS75A, LYS91A, MET29A, MET41B, MET47A, PHE17A, PHE18A, PHE33A, PHE64B, PHE74A, PRO103B, PRO107B, PRO24B, PRO38A, PRO39B, PRO40A, PRO4B, PRO50B, PRO53B, PRO7B, PRO8A, SER19A, SER34A, SER43A, SER55A, SER57A, SER81B, SER85A, SER92A, SER96B, THR109B, THR11A, THR15B, THR31B, THR32B, THR39A, THR40B, THR42B, THR46A, THR54A, THR58A, THR69A, THR86A, THR97B, THR98B, TYR37A, TYR37B, TYR59B, TYR65A, TYR82B, TYR88A, TYR89A, VAL18B, VAL29B, VAL44B, VAL48B, VAL49A, VAL53A, VAL55B, VAL56B, VAL61A, VAL62B, VAL68A, VAL70A, VAL76A, VAL80B, VAL84B
• A-L: ARG54L, ASN15A, ASN34L, ASP96L, GLN20A, GLN27A, GLN38L, GLN93L, GLN94L, GLU97L, GLY33L, GLY72A, GLY73A, MET101L, MET29A, MET37L, MET71A, PHE17A, PHE18A, PHE36L, PHE74A, PRO16A, SER19A, SER35L, SER95L, TYR100L, TYR102L, TYR53L, TYR98L, VAL70A, VAL76A
• A-H: ALA23A, ARG56H, ARG98H, ARG99H, ASN102H, ASN15A, ASN52H, ASN54H, ASP105H, GLN13A, GLN20A, GLU14A, GLU50H, GLY101H, GLY22A, GLY55H, GLY72A, ILE25A, ILE51H, LEU26A, MET34H, MET71A, PHE17A, PHE18A, PHE29H, PHE74A, PRO16A, PRO21A, PRO24A, PRO52H, SER19A, SER31H, THR30H, THR53H, TRP33H, TRP47H, TYR100H, TYR32H, TYR59H, VAL70A
• A-M: ALA225M, ASN293M, ASN52A, ASP201M, GLN50A, GLU203M, GLU227M, ILE202M, LEU41A, LYS44A, LYS45A, LYS51A, MET47A, PRO295M, PRO38A, SER226M, THR228M, THR269M, THR39A, TYR292M, VAL49A, VAL53A
• B-L: ARG43B, ARG72L, ASN34L, GLN46B, GLU97L, GLY33L, LEU45B, LEU52B, MET41B, PHE36L, PRO53B, PRO99L, SER31L, SER35L, THR42B, TYR32L, TYR98L, VAL44B
• B-H: ASN102H, LEU45B
• B-M: ALA225M, ALA268M, ALA83B, ARG63B, ARG68B, ARG74B, ASN293M, ASN77B, ASP201M, ASP230M, ASP270M, CYS23B, GLN290M, GLU19B, GLU21B, GLU227M, GLU65B, GLY22B, GLY75B, HIS294M, ILE202M, ILE67B, LYS20B, PHE232M, PHE64B, PRO295M, PRO78B, SER226M, SER231M, SER267M, SER66B, SER81B, SER96B, THR228M, THR269M, THR291M, THR97B, TYR292M, TYR296M, TYR82B, VAL18B, VAL229M, VAL62B, VAL76B, VAL79B, VAL80B
• B-I: ALA302I, ALA303I, ARG272I, ARG298I, ARG68B, ARG74B, ASN253I, ASN77B, ASP233I, CYS23B, CYS72B, GLN299I, GLN304I, GLU21B, GLY22B, GLY255I, GLY300I, GLY71B, GLY75B, ILE251I, LYS20B, LYS265I, MET234I, PHE229I, PHE232I, PRO24B, PRO305I, PRO73B, PRO78B, SER230I, SER231I, SER250I, THR252I, THR256I, THR258I, THR301I, TRP307I, TYR257I, TYR259I, TYR306I, VAL254I, VAL76B, VAL79B
• L-H: ALA97H, ARG54L, ARG98H, ARG99H, ASN102H, ASN61H, ASP105H, ASP1L, ASP96L, CYS92L, CYS96H, GLN109H, GLN38L, GLN39H, GLN42L, GLN43H, GLN46L, GLN6H, GLN6L, GLN93L, GLN94L, GLU46H, GLU50H, GLU59L, GLU62H, GLU97L, GLY101H, GLY105L, GLY106L, GLY107L, GLY108H, GLY110H, GLY42H, GLY44H, GLY45L, GLY49H, HIS35H, ILE48H, ILE52L, LEU45H, LEU4H, LEU50L, LYS38H, LYS43L, LYS49L, MET101L, MET37L, PHE104H, PHE104L, PHE36L, PRO47L, PRO48L, PRO99L, SER103H, SER35L, SER60L, SER95L, THR103L, THR111H, THR89L, TRP107H, TRP33H, TRP36H, TRP39L, TRP47H, TYR100H, TYR100L, TYR102L, TYR106H, TYR40L, TYR53L, TYR59H, TYR60H, TYR91L, TYR95H, VAL37H, VAL93H
• M-I: ALA249I, ALA251M, ALA297I, ALA314I, ARG238I, ARG244I, ARG298I, ASN253M, ASN293M, ASP201M, ASP230M, ASP233I, ASP285M, ASP310I, CYS288M, CYS296I, GLN205I, GLN206M, GLN238M, GLN239I, GLN242M, GLN290M, GLN299I, GLN304I, GLU203M, GLU206I, GLU241M, GLU242I, GLU246I, GLY250M, GLY262I, GLY289M, GLY299M, GLY300I, GLY300M, GLY301M, GLY313I, GLY315I, HIS287M, HIS294M, ILE237I, ILE248M, LEU204I, LEU204M, LEU245I, LEU246M, LEU247M, LEU293I, LYS209M, LYS239M, LYS243I, LYS245M, LYS265I, LYS303M, PHE232M, PHE249M, PHE255M, PHE295I, PHE298M, PHE309I, PRO244M, PRO261I, PRO295M, PRO305I, SER210M, SER231M, SER234M, SER235I, SER243M, SER250I, SER252M, SER256M, SER263I, THR252I, THR258I, THR291M, THR297M, THR301I, THR302M, TRP235M, TRP236I, TRP247I, TRP307I, TRP312I, TYR236M, TYR259I, TYR260I, TYR286M, TYR292M, TYR296M, TYR306I, TYR308I, VAL233M, VAL248I, VAL311I