1Q7L

zn-binding domain of the t347g mutant of human aminoacylase- i

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 219
  • Norm. En. per Res.: -7.9201
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-373.1731	-130.7108	-1230.61	-1734.4938	219	46	42	42444	14	69	69
A-C	0.0	0.0	-114.724	-114.724	63	0	0	4548	0	10	5
A-D	0.0	-7.8782	-59.8714	-67.7496	48	0	4	2582	0	9	5
B-C	0.0	-7.7349	-60.5769	-68.3118	48	0	4	2594	0	9	5
B-D	-14.0046	7.9802	-59.2918	-65.3162	38	6	2	2123	5	12	16
C-D	-325.3992	-92.7024	-1216.66	-1634.7617	216	45	42	41897	9	68	67

Interface residues

• A-B: ALA108A, ALA111A, ALA124A, ALA169A, ALA172A, ALA178A, ALA183A, ALA325B, ALA326B, ALA345B, ALA346B, ALA354B, ALA359B, ALA382B, ALA397B, ALA399B, ALA403B, ALA98A, ARG109A, ARG126A, ARG127A, ARG134A, ARG137A, ARG161A, ARG168A, ARG17A, ARG191A, ARG197A, ARG350B, ARG353B, ARG367B, ARG378B, ARG386B, ARG393B, ASN179A, ASN321B, ASN335B, ASN349B, ASN366B, ASN69A, ASN78A, ASP101A, ASP113A, ASP146A, ASP174A, ASP182A, ASP348B, ASP374B, ASP376B, ASP389B, ASP407B, ASP82A, ASP94A, CYS116A, CYS331B, GLN112A, GLN120A, GLN153A, GLN160A, GLU103A, GLU123A, GLU131A, GLU147A, GLU148A, GLU156A, GLU175A, GLU190A, GLU339B, GLU341B, GLU377B, GLU381B, GLU89A, GLU8A, GLU9A, GLY104A, GLY110A, GLY150A, GLY151A, GLY154A, GLY170A, GLY176A, GLY347B, GLY356B, GLY361B, GLY387B, GLY67A, HIS10A, HIS133A, HIS152A, HIS165A, HIS373B, HIS375B, HIS380B, HIS80A, HIS90A, HIS93A, ILE106A, ILE119A, ILE139A, ILE177A, ILE342B, ILE352B, ILE390B, ILE75A, LEU122A, LEU128A, LEU157A, LEU15A, LEU167A, LEU173A, LEU20A, LEU336B, LEU338B, LEU360B, LEU371B, LEU372B, LEU379B, LEU385B, LEU394B, LEU395B, LEU398B, LEU404B, LEU72A, LEU76A, LEU77A, LYS100A, LYS115A, LYS129A, LYS88A, MET114A, MET141A, MET155A, MET334B, MET343B, MET365B, PHE135A, PHE143A, PHE158A, PHE164A, PHE16A, PHE171A, PHE184A, PHE187A, PHE327B, PHE362B, PHE384B, PHE87A, PHE99A, PRO11A, PRO136A, PRO145A, PRO180A, PRO193A, PRO322B, PRO340B, PRO344B, PRO358B, PRO364B, PRO369B, PRO396B, PRO402B, PRO405B, PRO85A, PRO95A, SER102A, SER118A, SER12A, SER189A, SER192A, SER328B, SER363B, SER400B, SER406B, SER408B, SER73A, SER74A, SER79A, SER92A, THR138A, THR142A, THR14A, THR181A, THR185A, THR337B, THR368B, THR392B, THR68A, THR71A, THR81A, TRP194A, TRP195A, TRP323B, TRP324B, TRP65A, TRP91A, TYR105A, TYR107A, TYR121A, TYR188A, TYR19A, TYR351B, TYR391B, VAL117A, VAL125A, VAL13A, VAL144A, VAL149A, VAL159A, VAL186A, VAL196A, VAL355B, VAL357B, VAL370B, VAL383B, VAL388B, VAL401B, VAL83A, VAL84A, VAL86A
• A-C: ARG197A, ARG197C, ASP146A, ASP146C, ASP82A, ASP82C, GLN153C, GLN26A, GLN26C, GLU147A, GLU147C, GLU148A, GLU148C, GLU156A, GLU156C, GLU190A, GLU190C, GLY150A, GLY150C, HIS152A, HIS152C, HIS90A, HIS90C, ILE177A, ILE177C, LYS28A, LYS28C, PHE187A, PHE187C, PHE87A, PHE87C, PRO180A, PRO180C, PRO193A, PRO193C, PRO27A, PRO27C, PRO29A, PRO29C, PRO85A, PRO85C, SER189A, SER189C, TRP194A, TRP194C, TRP195A, TRP195C, TYR188A, TYR188C, TYR58C, VAL149A, VAL149C, VAL186A, VAL186C, VAL196A, VAL196C, VAL198A, VAL25A, VAL25C, VAL83A, VAL83C, VAL84A, VAL84C
• A-D: ALA178A, ALA183A, ALA345D, ALA346D, ARG109A, ARG350D, ARG378D, ASN179A, ASP374D, GLN26A, GLU147A, GLU148A, GLU339D, GLU341D, GLU89A, GLY150A, GLY151A, HIS152A, HIS373D, HIS375D, HIS90A, ILE177A, ILE342D, LEU338D, LEU371D, LEU372D, LYS88A, MET343D, PHE187A, PHE87A, PRO180A, PRO340D, PRO344D, PRO369D, PRO85A, THR181A, THR185A, TRP194A, TRP324D, TRP91A, TYR351D, VAL149A, VAL186A, VAL25A, VAL370D, VAL83A, VAL84A, VAL86A
• B-C: ALA178C, ALA183C, ALA345B, ALA346B, ARG109C, ARG350B, ARG378B, ASN179C, ASP374B, GLN26C, GLU147C, GLU148C, GLU339B, GLU341B, GLU89C, GLY150C, GLY151C, HIS152C, HIS373B, HIS375B, HIS90C, ILE177C, ILE342B, LEU338B, LEU371B, LEU372B, LYS88C, MET343B, PHE187C, PHE87C, PRO180C, PRO340B, PRO344B, PRO369B, PRO85C, THR181C, THR185C, TRP194C, TRP324B, TRP91C, TYR351B, VAL149C, VAL186C, VAL25C, VAL370B, VAL83C, VAL84C, VAL86C
• B-D: ALA345B, ALA345D, ALA346B, ALA346D, ARG350D, ASP374B, ASP374D, ASP376B, ASP376D, GLU339B, GLU339D, GLU341B, GLU341D, GLU377B, GLU377D, HIS373B, HIS373D, HIS375B, HIS375D, ILE342B, ILE342D, LEU338B, LEU338D, LEU371B, LEU371D, LEU372B, LEU372D, MET343B, MET343D, PRO340B, PRO340D, PRO344B, PRO344D, PRO369B, PRO369D, TYR351B, VAL370B, VAL370D
• C-D: ALA108C, ALA111C, ALA124C, ALA169C, ALA172C, ALA178C, ALA183C, ALA325D, ALA326D, ALA345D, ALA346D, ALA354D, ALA359D, ALA382D, ALA397D, ALA399D, ALA403D, ALA98C, ARG109C, ARG126C, ARG127C, ARG134C, ARG137C, ARG161C, ARG168C, ARG17C, ARG191C, ARG197C, ARG350D, ARG353D, ARG367D, ARG378D, ARG386D, ARG393D, ASN179C, ASN321D, ASN335D, ASN349D, ASN366D, ASN69C, ASN78C, ASP101C, ASP113C, ASP146C, ASP174C, ASP182C, ASP348D, ASP374D, ASP376D, ASP389D, ASP82C, ASP94C, CYS116C, CYS331D, GLN112C, GLN120C, GLN153C, GLN160C, GLU103C, GLU123C, GLU131C, GLU147C, GLU148C, GLU156C, GLU175C, GLU190C, GLU339D, GLU341D, GLU377D, GLU381D, GLU89C, GLU8C, GLU9C, GLY104C, GLY110C, GLY150C, GLY151C, GLY154C, GLY170C, GLY176C, GLY347D, GLY356D, GLY361D, GLY387D, GLY67C, HIS10C, HIS133C, HIS152C, HIS165C, HIS373D, HIS375D, HIS380D, HIS80C, HIS90C, HIS93C, ILE106C, ILE119C, ILE139C, ILE177C, ILE342D, ILE352D, ILE390D, ILE75C, LEU122C, LEU128C, LEU157C, LEU15C, LEU167C, LEU173C, LEU20C, LEU336D, LEU338D, LEU360D, LEU371D, LEU372D, LEU379D, LEU385D, LEU394D, LEU395D, LEU398D, LEU404D, LEU72C, LEU76C, LEU77C, LYS100C, LYS115C, LYS129C, LYS88C, MET114C, MET141C, MET155C, MET334D, MET343D, MET365D, PHE135C, PHE143C, PHE158C, PHE164C, PHE16C, PHE171C, PHE184C, PHE187C, PHE327D, PHE362D, PHE384D, PHE87C, PHE99C, PRO11C, PRO136C, PRO145C, PRO180C, PRO193C, PRO322D, PRO340D, PRO344D, PRO358D, PRO364D, PRO369D, PRO396D, PRO402D, PRO405D, PRO85C, PRO95C, SER102C, SER118C, SER12C, SER189C, SER192C, SER328D, SER363D, SER400D, SER73C, SER74C, SER79C, SER92C, THR138C, THR142C, THR14C, THR181C, THR185C, THR337D, THR368D, THR392D, THR68C, THR71C, THR81C, TRP194C, TRP195C, TRP323D, TRP324D, TRP65C, TRP91C, TYR105C, TYR107C, TYR121C, TYR188C, TYR19C, TYR351D, TYR391D, VAL117C, VAL125C, VAL13C, VAL144C, VAL149C, VAL159C, VAL186C, VAL196C, VAL355D, VAL357D, VAL370D, VAL383D, VAL388D, VAL401D, VAL83C, VAL84C, VAL86C