1Q3A

crystal structure of the catalytic domain of human matrix metalloproteinase 10

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 54
  • Norm. En. per Res.: -1.9559
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-14.3192	-1.7876	-89.5125	-105.6193	54	4	1	3805	0	18	21
A-C	0.0	-2.4542	-49.9597	-52.4139	40	2	1	2199	0	13	9
B-C	-8.1793	-2.6989	-106.966	-117.8443	67	16	2	5409	0	24	19

Interface residues

• A-B: ALA181A, ALA206A, ALA229A, ALA229B, ALA246A, ASN170B, ASN210A, ASN230A, ASN240A, ASP169B, ASP174B, ASP199A, ASP199B, ASP205A, GLU166B, GLU200A, GLU232A, GLY168B, GLY175A, GLY175B, GLY177A, GLY177B, GLY208A, HIS167B, HIS178A, HIS178B, HIS182B, HIS227B, LEU180A, LEU180B, LEU238A, LEU238B, LEU245A, LYS165B, LYS201A, PHE173B, PRO176A, PRO176B, PRO237A, PRO237B, SER172B, SER179A, SER179B, SER207A, SER228B, SER241A, THR203A, THR209A, THR231A, TYR171B, TYR236A, TYR236B, TYR239A, TYR239B
• A-C: ALA206C, ALA229A, ASN230A, ASN240C, ASP174C, ASP199C, ASP205C, ASP253A, GLU200C, GLY175C, GLY177C, GLY208C, GLY224A, HIS178A, HIS178C, HIS221A, HIS227A, LEU180C, LEU225A, LEU238A, LEU238C, LYS165C, LYS201C, MET105A, PHE226A, PRO106A, PRO176C, PRO185A, PRO237A, SER179A, SER179C, SER207C, SER228A, SER241C, THR203C, THR209C, THR231A, TYR236A, TYR239A, TYR239C
• B-C: ALA181B, ALA181C, ALA183C, ALA206B, ALA229B, ALA229C, ASN170C, ASN210B, ASN230B, ASN240B, ASP169C, ASP174C, ASP193C, ASP205B, GLN247B, GLU166C, GLU218C, GLU232B, GLU244B, GLY168C, GLY175C, GLY177B, GLY177C, GLY208B, HIS167C, HIS178B, HIS178C, HIS182C, HIS195C, HIS221C, HIS227C, ILE194C, LEU180B, LEU180C, LEU190C, LEU238B, LEU238C, LEU245B, LYS165C, LYS201B, MET235C, PHE173C, PHE226C, PHE242B, PRO176B, PRO176C, PRO185C, PRO237B, PRO237C, SER172C, SER179B, SER179C, SER207B, SER228C, SER241B, THR203B, THR209B, THR231B, THR231C, THR243B, TYR171C, TYR184C, TYR191C, TYR236B, TYR236C, TYR239B, TYR239C